The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease

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α-Synuclein Locus Triplication Causes Parkinson's Disease

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AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease

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Hereditary Early-Onset Parkinson's Disease Caused by Mutations in <i>PINK1</i>

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Mitochondrial diseases in man and mouse

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The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

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The many faces of α-synuclein: from structure and toxicity to therapeutic target

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The mitochondrial basis of aging

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ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease

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Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

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Mitochondrial pathology and apoptotic muscle degeneration in <i>Drosophila parkin</i> mutants

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Clinical Neurology and Epidemiology of the Major Neurodegenerative DiseasesPreprint

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Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

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Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice

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Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

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Measuring In Vivo Mitophagy

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Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

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α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

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Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein*♦

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Positron Emission Tomography in the Study of Aging and Senile Dementia

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Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease

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Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase

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Positron emission tomographic studies of aging and Alzheimer disease.

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Quantitative determination of deleted mitochondrial DNA relative to normal DNA in parkinsonian striatum by a kinetic PCR analysis

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Cytochrome <i>c</i> oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease

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shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease model

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A mitochondrial DNA clone is associated with increased risk for Alzheimer disease.

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Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy

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Role of Mitochondrial Amyloid-β in Alzheimer's Disease

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Modeling Parkinson's Disease in Primates: The MPTP ModelPreprint

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Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD

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Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways.

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Parkinson's disease, pesticides and mitochondrial dysfunction

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Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins

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Mitochondrial DNA mutations in neurodegeneration

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Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells

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Neuronal Calcium Signaling, Mitochondrial Dysfunction, and Alzheimer's Disease

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Decreased medial temporal oxygen metabolism in Alzheimer's disease shown by PET.

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Multiple system atrophy: a clinical and neuropathological perspective

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Systemic Mitochondrial Dysfunction and the Etiology of Alzheimer's Disease and Down Syndrome Dementia

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Mitochondrial respiratory chain activity in the human brain as a function of age

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Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease

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Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease

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Increased risk of dementia in mothers of Alzheimer's disease cases: Evidence for maternal inheritance

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Point mutations of mitochondrial genome in Parkinson's disease

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Aging-induced alterations in gene transcripts and functional activity of mitochondrial oxidative phosphorylation complexes in the heart

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Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease

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Increased fibrillar amyloid-β burden in normal individuals with a family history of late-onset Alzheimer’s

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Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease

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M itochondrial DNA and primary mitochondrial dysfunction in P arkinson's disease

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Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

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Mitochondrial dysfunction in neurodegenerative disorders

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Mitochondria and Brain Disease: A Comprehensive Review of Pathological Mechanisms and Therapeutic Opportunities

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Altered glucose metabolism in Alzheimer's disease: Role of mitochondrial dysfunction and oxidative stress

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The RING finger protein family in health and disease

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The Muscle-Brain Axis and Neurodegenerative Diseases: The Key Role of Mitochondria in Exercise-Induced Neuroprotection

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Mitochondria-Targeted Antioxidants, an Innovative Class of Antioxidant Compounds for Neurodegenerative Diseases: Perspectives and Limitations

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Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases

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In Response to Precision Medicine: Current Subcellular Targeting Strategies for Cancer Therapy

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Mitochondria at Work: New Insights into Regulation and Dysregulation of Cellular Energy Supply and Metabolism

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Mitochondria on the move: Horizontal mitochondrial transfer in disease and health

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New Promising Therapeutic Avenues of Curcumin in Brain Diseases

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Mitochondria Dysfunction and Neuroinflammation in Neurodegeneration: Who Comes First?

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Disentangling Mitochondria in Alzheimer’s Disease

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Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy

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The calcium–iron connection in ferroptosis-mediated neuronal death

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Neuropathological assessment of the Alzheimer spectrum

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Protective Effects of Pioglitazone on Cognitive Impairment and the Underlying Mechanisms: A Review of Literature

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Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies for analysis and therapeutic prospects

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Role of mitochondria in physiological activities, diseases, and therapy

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Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review

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Nano‐Brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits

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Mitochondrial metabolism in neural stem cells and implications for neurodevelopmental and neurodegenerative diseases

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Understanding the Multiple Role of Mitochondria in Parkinson’s Disease and Related Disorders: Lesson From Genetics and Protein–Interaction Network

Nicoletti, V., Palermo, G., Prete, E. D., Mancuso, M., & Ceravolo, R. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.636506 · Cited by 72 · see citing works

The potential role of mitochondria in the microbiota-gut-brain axis: Implications for brain health

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Pharmacological approaches to enhance mitochondrial biogenesis: focus on PGC-1Α, AMPK, and SIRT1 in cellular health

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AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma

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Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome

Panagaki, T., Lozano‐Montes, L., Janickova, L., Zuhra, K., Szabo, M. P., Majtán, T., Rainer, G., Maréchal, D., Hérault, Y., & Szabó, C. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102233 · Cited by 64 · see citing works

Mitochondria in brain diseases: Bridging structural-mechanistic insights into precision-targeted therapies

Liao, J., He, W., Li, L., Wang, J., Gong, L., Zhang, Q., & Lin, Z. (2025) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100016 · Cited by 62 · see citing works

Mitophagy in aging and longevity

Guo, J., & Chiang, W. (2021) · IUBMB Life · doi:10.1002/iub.2585 · Cited by 58 · see citing works

Pathological and Therapeutic Advances in Parkinson’s Disease: Mitochondria in the Interplay

Naren, P., Cholkar, A., Kamble, S., Khan, S. S., Srivastava, S., Madan, J., Mehra, N. K., Tiwari, V., Singh, S. B., & Khatri, D. K. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220682 · Cited by 57 · see citing works

Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

Choudhury, D., Rong, N., Kumar, H. V. S., Swedick, S., Samuel, R. Z., Mehrotra, P., Toftegaard, J., Rajabian, N., Thiyagarajan, R., Podder, A. K., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113738 · Cited by 56 · see citing works

Fine Particulate Matter Triggers α‐Synuclein Fibrillization and Parkinson‐like Neurodegeneration

Yuan, X., Yang, Y., Liu, C., Tian, Y., Xia, D., Liu, Z., Pan, L., Xiong, M., Xiong, J., Meng, L., et al. (2022) · Movement Disorders · doi:10.1002/mds.29181 · Cited by 55 · see citing works

BDNF-TrkB Signaling in Mitochondria: Implications for Neurodegenerative Diseases

Soman, S. K., Swain, M., & Dagda, R. K. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04357-4 · Cited by 54 · see citing works

Mitochondria transplantation transiently rescues cerebellar neurodegeneration improving mitochondrial function and reducing mitophagy in mice

Li, S., Zheng, Q., Zheng, J., Zhang, J., Liu, H., Tie, J.-J., Zhang, K.-L., Wu, F., Li, X.-D., Zhang, S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-58189-4 · Cited by 51 · see citing works

Understanding the contributions of VPS35 and the retromer in neurodegenerative disease

Williams, E. T., Chen, X., Otero, P. A., & Moore, D. J. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105768 · Cited by 49 · see citing works

Sphingolipids in neurodegenerative diseases

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Role of Phytonutrients in the Prevention and Treatment of Chronic Diseases: A Concrete Review

Tufail, T., Fatima, S., Ain, H. B. U., Ikram, A., Noreen, S., Ребезов, М. Б., AL-Farga, A. M., Saleh, R. A., & Shariati, M. A. (2025) · ACS Omega · doi:10.1021/acsomega.4c02927 · Cited by 49 · see citing works

From mitochondrial dysfunction to neuroinflammation in Parkinson’s disease: Pathogenesis and mitochondrial therapeutic approaches

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Is there a special relationship between complex I activity and nigral neuronal loss in Parkinson’s disease? A critical reappraisal

Subrahmanian, N., & LaVoie, M. J. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147434 · Cited by 48 · see citing works

CNS Delivery of Nucleic Acid Therapeutics: Beyond the Blood–Brain Barrier and Towards Specific Cellular Targeting

D’souza, A. A., Nozohouri, S., Bleier, B. S., & Amiji, M. M. (2022) · Pharmaceutical Research · doi:10.1007/s11095-022-03433-5 · Cited by 47 · see citing works

Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunction

Jia, D., Tian, Z., & Wang, R. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102087 · Cited by 47 · see citing works

Liquid crystalline lipid nanoparticles for combined delivery of curcumin, fish oil and BDNF: In vitro neuroprotective potential in a cellular model of tunicamycin-induced endoplasmic reticulum stress

Rakotoarisoa, M., Angelov, B., Drechsler, M., Nicolas, V., Bizien, T., Gorshkova, Y. E., Deng, Y., & Angelova, A. (2022) · Smart Materials in Medicine · doi:10.1016/j.smaim.2022.03.001 · Cited by 46 · see citing works

Role of Mitochondrial Dysfunctions in Neurodegenerative Disorders: Advances in Mitochondrial Biology

Kathiresan, D. S., Balasubramani, R., Marudhachalam, K., Jaiswal, P., Ramesh, N., Suruthi, G. S., Moorthi, P. V., & Vijayan, M. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04469-x · Cited by 46 · see citing works

New Insights into Mitochondria in Health and Diseases

Li, Y., Zhang, H., Yu, C., Dong, X., Yang, F., Wang, M., Wen, Z., Su, M., Li, B., & Yang, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189975 · Cited by 46 · see citing works

Neuropathology of the Alzheimer's continuum: an update

Jellinger, K. A. (2020) · Free Neuropathology · doi:10.17879/freeneuropathology-2020-3050 · Cited by 45 · see citing works

Contribution of Mitochondrial Dysfunction Combined with NLRP3 Inflammasome Activation in Selected Neurodegenerative Diseases

Litwiniuk, A., Baranowska-Bik, A., Domańska, A., Kalisz, M., & Bik, W. (2021) · Pharmaceuticals · doi:10.3390/ph14121221 · Cited by 45 · see citing works

DDHD2 provides a flux of saturated fatty acids for neuronal energy and function

Saber, S. H., Yak, N., Yong, X. L. H., Bong, Y. T., Leeson, H. C., Dai, C.-Y., Binder, T., Lu, S., Purushothaman, R., Lenaerts, A.-S., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01367-x · Cited by 43 · see citing works

Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD

Iba, M., Kim, C., Kwon, S., Szabo, M. P., Horan-Portelance, L., Peer, C. J., Figg, W. D., Reed, X., Ding, J., Lee, S., et al. (2023) · Science Translational Medicine · doi:10.1126/scitranslmed.abq6089 · Cited by 42 · see citing works

Decoding metabolic signatures in Alzheimer’s disease: a mitochondrial perspective

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The Potentiality of Natural Products and Herbal Medicine as Novel Medications for Parkinson’s Disease: A Promising Therapeutic Approach

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Redox Homeostasis, Gut Microbiota, and Epigenetics in Neurodegenerative Diseases: A Systematic Review

Munteanu, C., Galaction, A., Turnea, M. A., Blendea, C. D., Rotariu, M., & Poştaru, M. (2024) · Antioxidants · doi:10.3390/antiox13091062 · Cited by 41 · see citing works

Mitochondria‐Targeted Molecular Tools in Precise Tumor Therapy

Wang, X., Tang, Y., & Li, Q. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202511230 · Cited by 40 · see citing works

The Emerging Roles of E3 Ligases and DUBs in Neurodegenerative Diseases

Liu, N., Lin, M., & Wang, Y. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03063-3 · Cited by 39 · see citing works

Role of the mtDNA Mutations and Mitophagy in Inflammaging

Dabravolski, S. A., Nikiforov, N. G., Zhuravlev, A. D., Orekhov, N. A., Grechko, A. V., & Orekhov, A. N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031323 · Cited by 38 · see citing works

Teaghrelin protected dopaminergic neurons in MPTP ‐induced Parkinson's disease animal model by promoting PINK1 /Parkin‐mediated mitophagy and AMPK / SIRT1 / PGC1 ‐α‐mediated mitochondrial biogenesis

Jhuo, C., Chen, C., Tzen, J. T. C., & Chen, W. (2024) · Environmental Toxicology · doi:10.1002/tox.24275 · Cited by 37 · see citing works

Nitric oxide and dopamine metabolism converge via mitochondrial dysfunction in the mechanisms of neurodegeneration in Parkinson's disease

Nunes, C., & Laranjinha, J. A. N. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108877 · Cited by 37 · see citing works

Role of PITRM1 in Mitochondrial Dysfunction and Neurodegeneration

Brunetti, D., Catania, A., Viscomi, C. F., Deleidi, M., Bindoff, L. A., Ghezzi, D., & Zeviani, M. (2021) · Biomedicines · doi:10.3390/biomedicines9070833 · Cited by 37 · see citing works

Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity

Pamies, D., Wiersma, D., Katt, M. E., Zhao, L., Burtscher, J., Harris, G., Smirnova, L., Searson, P. C., Härtung, T., & Högberg, H. T. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105719 · Cited by 37 · see citing works

Thymol as a Potential Neuroprotective Agent: Mechanisms, Efficacy, and Future Prospects

Peng, X., Zhang, X., Sharma, G., & Dai, C. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06461 · Cited by 36 · see citing works

C. elegans as a model to study mitochondrial biology and disease

Onraet, T., & Zuryn, S. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.04.006 · Cited by 36 · see citing works

The multifaceted role of quercetin derived from its mitochondrial mechanism

Carrillo-Garmendia, A., Pérez, L. A. M., & Regalado‐González, C. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04833-w · Cited by 35 · see citing works

Mitochondria and Other Organelles in Neural Development and Their Potential as Therapeutic Targets in Neurodegenerative Diseases

Zhang, S., Zhao, J., Quan, Z., Li, H., & Qing, H. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.853911 · Cited by 35 · see citing works

Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming

Wang, D., Gu, X. Q., Ma, X., Chen, J., Zhang, Q., Yu, Z., Li, J., Meng, H., Tan, X., Tang, Y., et al. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.07.014 · Cited by 35 · see citing works

Upregulated ECM genes and increased synaptic activity in Parkinson’s human DA neurons with PINK1/ PRKN mutations

Tripathi, U., Rosh, I., Ezer, R. B., Nayak, R., Hussein, Y., Choudhary, A., Djamus, J., Manole, A., Houlden, H., Gage, F. H., et al. (2024) · npj Parkinson s Disease · doi:10.1038/s41531-024-00715-0 · Cited by 34 · see citing works

Alzheimer’s Disease: Exploring Pathophysiological Hypotheses and the Role of Machine Learning in Drug Discovery

Dominguez-Gortaire, J. A., Ruiz, A., Porto-Pazos, A. B., Rodríguez, S., & Cedrón, F. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031004 · Cited by 34 · see citing works

Exploring Stressors: Impact on Cellular Organelles and Implications for Cellular Functions

Zayani, Z., Matinahmadi, A., Tavakolpournegari, A., & Bidooki, S. H. (2025) · Stresses · doi:10.3390/stresses5020026 · Cited by 34 · see citing works

'Fly-ing' from rare to common neurodegenerative disease mechanisms

Ma, M., Moulton, M. J., Lu, S., & Bellen, H. J. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.03.018 · Cited by 34 · see citing works

Boosting mitochondrial health to counteract neurodegeneration

Burtscher, J., Romani, M., Bernardo, G., Popa, T., Ziviani, E., Hummel, F. C., Sorrentino, V., & Millet, G. P. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2022.102289 · Cited by 34 · see citing works

Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing

Jagtap, Y. A., Kumar, P., Kinger, S., Dubey, A. R., Choudhary, A., Gutti, R. K., Singh, S., Jha, H. C., Poluri, K. M., & Mishra, A. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1146564 · Cited by 33 · see citing works

Mitochondrial Complex I and β-Amyloid Peptide Interplay in Alzheimer’s Disease: A Critical Review of New and Old Little Regarded Findings

Atlante, A., & Valenti, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115951 · Cited by 32 · see citing works

Advanced nano delivery system for stem cell therapy for Alzheimer's disease

Pan, Y., Li, L., Cao, N., Liao, J., Chen, H., & Zhang, M. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122852 · Cited by 32 · see citing works

Intermittent fasting and neurodegenerative diseases: Molecular mechanisms and therapeutic potential

Lv, R., Liu, B., Jiang, Z., Zhou, R., Liu, X., Lu, T., Bao, Y., Huang, C., Zou, G., Zhang, Z., et al. (2024) · Metabolism · doi:10.1016/j.metabol.2024.156104 · Cited by 32 · see citing works

The evolution of Alzheimer’s disease: From mitochondria to microglia

Yang, F., Liang, Y., Wang, X., Wang, J.-T., Gao, W., Ye, Q.-Y., Li, X., Yu, Y., & Li, H. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102838 · Cited by 32 · see citing works

The complex effects of miR-146a in the pathogenesis of Alzheimer’s disease

Long, Y., Liu, J., Wang, Y., Guo, H.-D., & Cui, G.-H. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01566 · Cited by 31 · see citing works

Interaction between resveratrol and SIRT1: role in neurodegenerative diseases

Zhu, L., Yang, M., Fan, L., Yan, Q., Zhang, L., Mu, P., & Lu, F. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03319-w · Cited by 31 · see citing works

Exploring glycolytic enzymes in disease: potential biomarkers and therapeutic targets in neurodegeneration, cancer and parasitic infections

Rojas-Pirela, M., Andrade-Alviárez, D., Rojas, V., Marcos, M., Salete-Granado, D., Chacón-Arnaude, M., Pérez-Nieto, M. Á., Kemmerling, U., Concepción, J. L., Michels, P. A. M., et al. (2025) · Open Biology · doi:10.1098/rsob.240239 · Cited by 31 · see citing works

Mitochondrial Ataxias: Molecular Classification and Clinical Heterogeneity

Lopriore, P., Ricciarini, V., Siciliano, G., Mancuso, M., & Montano, V. (2022) · Neurology International · doi:10.3390/neurolint14020028 · Cited by 31 · see citing works

Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms

Liu, C., Liu, Z., Fang, Y., Liao, Z., Zhang, Z., Yuan, X., Yu, T., Yang, Y., Xiong, M., Zhang, X., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107696 · Cited by 31 · see citing works

Peripheral Mitochondrial Dysfunction: A Potential Contributor to the Development of Metabolic Disorders and Alzheimer’s Disease

Sultana, M. A., Hia, R. A., Akinsiku, O., & Hegde, V. K. (2023) · Biology · doi:10.3390/biology12071019 · Cited by 31 · see citing works

Potential Retinal Biomarkers in Alzheimer’s Disease

García-Bermúdez, M. Y., Vohra, R., Freude, K., van Wijngaarden, P., Martin, K. R. G., Thomsen, M. S., Aldana, B. I., & Kolko, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115834 · Cited by 30 · see citing works

Alpha-Synuclein Effects on Mitochondrial Quality Control in Parkinson’s Disease

Shen, L., & Dettmer, U. (2024) · Biomolecules · doi:10.3390/biom14121649 · Cited by 30 · see citing works

Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson’s Disease Pathology

Yuan, X., Yang, Y., Xia, D., Meng, L., He, M., Liu, C., & Zhang, Z. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.807988 · Cited by 30 · see citing works

Mitochondria Have Made a Long Evolutionary Path from Ancient Bacteria Immigrants within Eukaryotic Cells to Essential Cellular Hosts and Key Players in Human Health and Disease

Atlante, A., & Valenti, D. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45050283 · Cited by 30 · see citing works

Ubiquitin E3 ligases assisted technologies in protein degradation: Sharing pathways in neurodegenerative disorders and cancer

Kaushik, A., Parashar, S., Ambasta, R. K., & Kumar, P. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102279 · Cited by 28 · see citing works

Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice

Bobkova, N. V., Zhdanova, D., Belosludtseva, N. V., Penkov, N. V., & Mironova, G. D. (2021) · Experimental Biology and Medicine · doi:10.1177/15353702211056866 · Cited by 28 · see citing works

From the Structural and (Dys)Function of ATP Synthase to Deficiency in Age-Related Diseases

Garone, C., Pietra, A., & Nesci, S. (2022) · Life · doi:10.3390/life12030401 · Cited by 28 · see citing works

Mitochondrial Toxicant-Induced Neuronal Apoptosis in Parkinson’s Disease: What We Know so Far

Sivagurunathan, N., Gnanasekaran, P., & Latchoumycandane, C. (2023) · Degenerative Neurological and Neuromuscular Disease · doi:10.2147/dnnd.s361526 · Cited by 28 · see citing works

The interplay between mitochondrial dysfunction and NLRP3 inflammasome in multiple sclerosis: Therapeutic implications and animal model studies

Shadab, A., Abbasi‐Kolli, M., Saharkhiz, M., Ahadi, S. H., Shokouhi, B., & Nahand, J. S. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116673 · Cited by 27 · see citing works

Crosstalk between the DNA damage response and cellular senescence drives aging and age-related diseases

Ahmad, A., Braden, A. A., Khan, S., Xiao, J., & Khan, M. M. (2024) · Seminars in Immunopathology · doi:10.1007/s00281-024-01016-7 · Cited by 27 · see citing works

Mitochondrial RNA , a new trigger of the innate immune system

Grochowska, J., Czerwińska, J., Borowski, L. S., & Szczęsny, R. J. (2021) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1690 · Cited by 27 · see citing works

Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

Miedema, S. S. M., Mol, M. O., Koopmans, F., Hondius, D., van Nierop, P., Menden, K., Mestdagh, C. F. D. V., van Rooij, J., Ganz, A. B., Paliukhovich, I., et al. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01387-8 · Cited by 27 · see citing works

Mitochondrial Complex I, a Possible Sensible Site of cAMP Pathway in Aging

Signorile, A., & Rasmo, D. D. (2023) · Antioxidants · doi:10.3390/antiox12020221 · Cited by 27 · see citing works

Latest assessment methods for mitochondrial homeostasis in cognitive diseases

You, W., Li, Y., Liu, K., Mi, X., Li, Y., Guo, X., & Li, Z. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.382222 · Cited by 27 · see citing works

Super-resolution microscopies, technological breakthrough to decipher mitochondrial structure and dynamic.

Teixeira, P., Galland, R., & Chevrollier, A. (2024) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2024.01.006 · Cited by 26 · see citing works

TRPV4 Channel in Neurological Disease: from Molecular Mechanisms to Therapeutic Potential

Zhang, F., Mehta, H., Choudhary, H. H., Islam, R., & Hanafy, K. A. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04518-5 · Cited by 26 · see citing works

Citicoline/Coenzyme Q10/Vitamin B3 Fixed Combination Exerts Synergistic Protective Effects on Neuronal Cells Exposed to Oxidative Stress

Mastropasqua, L., Agnifili, L., Ferrante, C., Sacchi, M., Figus, M., Rossi, G. C. M., Brescia, L., Aloia, R., & Orlando, G. (2022) · Nutrients · doi:10.3390/nu14142963 · Cited by 26 · see citing works

Mitochondrial Medicine: A Promising Therapeutic Option Against Various Neurodegenerative Disorders

Almikhlafi, M. A., Karami, M. M., Jana, A., Alqurashi, T. M. A., Majrashi, M., Alghamdi, B. S. A., & Ashraf, G. M. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220830112408 · Cited by 26 · see citing works

The mechanisms of mitochondrial abnormalities that contribute to sleep disorders and related neurodegenerative diseases

Zhang, W., Liu, D., Yuan, M., & Zhu, L. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102307 · Cited by 25 · see citing works

The yin and yang of mitochondrial Ca2+ signaling in cell physiology and pathology

Filadi, R., & Greotti, E. (2020) · Cell Calcium · doi:10.1016/j.ceca.2020.102321 · Cited by 25 · see citing works

Recurrent non-severe hypoglycemia aggravates cognitive decline in diabetes and induces mitochondrial dysfunction in cultured astrocytes

Gao, R., Ren, L., Zhou, Y., Wang, L., Xie, Y., Zhang, M., Liu, X., Ke, S., Wu, K., Zheng, J., et al. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111192 · Cited by 25 · see citing works

Mitochondria Dysfunction and Neurodegenerative Disorders: Cause or Consequence

Morais, V. A., & Strooper, B. D. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100345 · Cited by 111 · see citing works

Mitochondrial dysfunction: A notable contributor to the progression of Alzheimer's and Parkinson's disease

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Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration

McInnes, J. (2013) · Translational Neurodegeneration · doi:10.1186/2047-9158-2-12 · Cited by 64 · see citing works

A mitochondrial etiology of Alzheimer and Parkinson disease

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Mitochondria in the pathophysiology of Alzheimer s and Parkinson s diseases

Onyango, I. G. (2017) · Frontiers in Bioscience · doi:10.2741/4521 · Cited by 107 · see citing works