CoChat
Sign Up
Cited by 39

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Recent Advances in Nanoplatforms for the Treatment of Osteosarcoma

Wu, Kunzhe, Yu, Beibei, Li, Di, Tian, Yangyang, Liu, Yan, Jiang, Jinlan·2022·Frontiers in Oncology
DOI 10.3389/fonc.2022.805978PMC PMC8885548
Open this paper in CoChat — free account

Abstract

Osteosarcoma (OS) is the most common primary bone tumor in children and young people. Traditional surgical excision combined with chemotherapy presents many limitations, such as resistance and systemic side effects of chemotherapy drugs, postoperative recurrence, and bone defects. Given these limitations, novel therapeutic modalities for OS treatment using nanometer-sized platform-based chemotherapeutic delivery have emerged as a promising alternative therapy. This form of therapy offers multiple advantages, such as accurate delivery of the drug to the tumor site and repair of limited bone defects after tumor resection. In this review, we briefly summarize nanoplatforms, including liposomes, polymeric nanoparticles, inorganic nanoparticles, nanomicelles, dendrimers, nanocapsules, and exosomes. The essential shortcomings involved in these nanoplatforms, such as poor stability, immunogenicity, insufficient circulation, and drug leakage are also discussed, and related solutions are briefly proposed. Finally, the application prospects of nanoplatforms in the treatment of OS are discussed.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3389/fonc.2022.805978

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Figures

Figure 1 Chol-SS-mPEG/HA-L designed for long circulation in vivo followed by receptor-mediated endocytosis and GSH-triggered cytoplasmic DOX release. Reproduced from (10) with permission from J Control Release.
Figure 1 Chol-SS-mPEG/HA-L designed for long circulation in vivo followed by receptor-mediated endocytosis and GSH-triggered cytoplasmic DOX release. Reproduced from (10) with permission from J Control Release.CC BY · PubMed Central
Figure 2 3DP scaffolds containing DMPC and DMPG formed liposomes loated with curcumin. In the presence of a buffer medium or an extracellular medium, liposome released, followed by curcumin released from the liposome. Reproduced from (12) with permission from ACS Appl Mater Interfaces.
Figure 2 3DP scaffolds containing DMPC and DMPG formed liposomes loated with curcumin. In the presence of a buffer medium or an extracellular medium, liposome released, followed by curcumin released from the liposome. Reproduced from (12) with permission from ACS Appl Mater Interfaces.CC BY · PubMed Central
Figure 3 Under 808 nm near-infrared (NIR) irradiation, SP@MX-TOB/GelMA multifunctional implants can effectively kill OS cells in conjunction with photothermal effect. In addition, SP@MX-TOB/GelMA loaded TOB showed good antibacterial properties. More importantly, the multifunctional implant has excellent cellular compatibility and osteogenic ability. Reproduced from (13) with permission from Curr Med Chem.
Figure 3 Under 808 nm near-infrared (NIR) irradiation, SP@MX-TOB/GelMA multifunctional implants can effectively kill OS cells in conjunction with photothermal effect. In addition, SP@MX-TOB/GelMA loaded TOB showed good antibacterial properties. More importantly, the multifunctional implant has excellent cellular compatibility and osteogenic ability. Reproduced from (13) with permission from Curr Med Chem.CC BY · PubMed Central
Figure 4 MCSC scaffolds were composed of M-type ferrite particles and mesoporous calcium silicate microspheres dispersed in chitosan membrane. The scaffolds showed good drug delivery performance under NIR laser irradiation, and the MCSC scaffolds also had excellent ability to promote new bone regeneration. Reproduced from (15) with permission from Sci Rep.
Figure 4 MCSC scaffolds were composed of M-type ferrite particles and mesoporous calcium silicate microspheres dispersed in chitosan membrane. The scaffolds showed good drug delivery performance under NIR laser irradiation, and the MCSC scaffolds also had excellent ability to promote new bone regeneration. Reproduced from (15) with permission from Sci Rep.CC BY · PubMed Central
Figure 5 PEG-GOFA/ICG nanoplatform is absorbed by OS cells through FA receptor-mediated endocytosis. Under NIR irradiation, PEG-GOFA/ICG nanoplatform has CHEMO-PDT synergistic effect to promote intracellular ROS production and release MTH1 inhibitor TH287 to enhance apoptosis induction of OS cells. Reproduced from (16) with permission from Acta Biomater.
Figure 5 PEG-GOFA/ICG nanoplatform is absorbed by OS cells through FA receptor-mediated endocytosis. Under NIR irradiation, PEG-GOFA/ICG nanoplatform has CHEMO-PDT synergistic effect to promote intracellular ROS production and release MTH1 inhibitor TH287 to enhance apoptosis induction of OS cells. Reproduced from (16) with permission from Acta Biomater.CC BY · PubMed Central

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 5 references

Research works printed but not linked: 100

  1. Corre, 2020, The Osteosarcoma Microenvironment: A Complex But Targetable Ecosystem, Cells, 9, 976, 10.3390/cells9040976 · DOI
  2. Lilienthal, 2020, Targeting Molecular Mechanisms Underlying Treatment Efficacy and Resistance in Osteosarcoma: A Review of Current and Future Strategies, Int J Mol Sci, 21, 6885, 10.3390/ijms21186885 · DOI
  3. Rivera Vargas, 2017, Danger Signals: Chemotherapy Enhancers, Immunol Rev, 280, 10.1111/imr.12581 · DOI
  4. Ritter, 2010, Osteosarcoma, Ann Oncol, 21, 10.1093/annonc/mdq276 · DOI
  5. Gan, 2019, Protein Corona of Metal-Organic Framework Nanoparticals: Study on the Adsorption Behavior of Protein and Cell Interaction, Int J Biol Macromol, 140, 10.1016/j.ijbiomac.2019.08.183 · DOI
  6. Yan, 2021, Peritumoral Microgel Reservoir for Long-Term Light-Controlled Triple-Synergistic Treatment of Osteosarcoma With Single Ultra-Low Dose, Small, 17, 10.1002/smll.202100479 · DOI
  7. Zhu, 2021, 3d-Printed Multifunctional Polyetheretherketone Bone Scaffold for Multimodal Treatment of Osteosarcoma and Osteomyelitis, ACS Appl Mater Interfaces, 13, 10.1021/acsami.1c10898 · DOI
  8. Wang, 2021, Mesoporous Polydopamine-Coated Hydroxyapatite Nano-Composites for ROS-Triggered Nitric Oxide-Enhanced Photothermal Therapy of Osteosarcoma, J Mater Chem B, 9, 10.1039/d1tb01084k · DOI
  9. Lu, 2018, New Directions for Drug Delivery in Cancer Therapy, Mol Pharm, 15, 10.1021/acs.molpharmaceut.8b00860 · DOI
  10. Chi, 2017, Redox-Sensitive and Hyaluronic Acid Functionalized Liposomes for Cytoplasmic Drug Delivery to Osteosarcoma in Animal Models, J Control Release, 10.1016/j.jconrel.2017.06.027 · DOI
  11. Caliskan, 2019, A New Therapeutic Combination for Osteosarcoma: Gemcitabine and Clofazimine Co-Loaded Liposomal Formulation, Int J Pharm, 557, 97, 10.1016/j.ijpharm.2018.12.041 · DOI
  12. Sarkar, 2019, Liposome-Encapsulated Curcumin-Loaded 3d Printed Scaffold for Bone Tissue Engineering, ACS Appl Mater Interfaces, 11, 10.1021/acsami.9b01218 · DOI
  13. Yin, 2020, MXene-Based Hydrogels Endow Polyetheretherketone With Effective Osteogenicity and Combined Treatment of Osteosarcoma and Bacterial Infection, ACS Appl Mater Interfaces, 12, 10.1021/acsami.0c14752 · DOI
  14. Yang, 2018, pH-Responsive Mesoporous ZSM-5 Zeolites/Chitosan Core-Shell Nanodisks Loaded With Doxorubicin Against Osteosarcoma, Mater Sci Eng C Mater Biol Appl, 85, 10.1016/j.msec.2017.12.024 · DOI
  15. Yang, 2018, Magnetic Mesoporous Calcium Sillicate/Chitosan Porous Scaffolds for Enhanced Bone Regeneration and Photothermal-Chemotherapy of Osteosarcoma, Sci Rep, 8, 7345, 10.1038/s41598-018-25595-2 · DOI
  16. Huang, 2020, Delivery of MutT Homolog 1 Inhibitor by Functionalized Graphene Oxide Nanoparticles for Enhanced Chemo-Photodynamic Therapy Triggers Cell Death in Osteosarcoma, Acta Biomater, 109, 10.1016/j.actbio.2020.04.009 · DOI
  17. Zhang, 2016, 3d-Printed Bioceramic Scaffolds With a Fe(3)O(4)/graphene Oxide Nanocomposite Interface for Hyperthermia Therapy of Bone Tumor Cells, J Mater Chem B, 4, 10.1039/c6tb00390g · DOI
  18. Yue, 2016, Bull Serum Albumin Coated Au@Agnanorods as SERS Probes for Ultrasensitive Osteosarcoma Cell Detection, Talanta, 150, 10.1016/j.talanta.2015.12.065 · DOI
  19. Tung, 2020, One-Stop Radiotherapeutic Targeting of Primary and Distant Osteosarcoma to Inhibit Cancer Progression and Metastasis Using 2dg-Grafted Graphene Quantum Dots, Nanoscale, 12, 10.1039/c9nr10823h · DOI
  20. Miao, 2017, Single-Walled Carbon Nanotube: One Specific Inhibitor of Cancer Stem Cells in Osteosarcoma Upon Downregulation of the Tgfβ1 Signaling, Biomaterials, 149, 29, 10.1016/j.biomaterials.2017.09.032 · DOI
  21. Li, 2020, Co-Delivery of Doxorubicin and Paclitaxel by Reduction/pH Dual Responsive Nanocarriers for Osteosarcoma Therapy, Drug Deliv, 27, 10.1080/10717544.2020.1785049 · DOI
  22. Xi, 2019, Dual Targeting Curcumin Loaded Alendronate-Hyaluronan- Octadecanoic Acid Micelles for Improving Osteosarcoma Therapy, Int J Nanomed, 14, 10.2147/ijn.S211981 · DOI
  23. Gonçalves, 2014, Dendrimer-Assisted Formation of Fluorescent Nanogels for Drug Delivery and Intracellular Imaging, Biomacromolecules, 15, 10.1021/bm401400r · DOI
  24. Wang, 2018, Ifosfamide-Loaded Lipid-Core-Nanocapsules to Increase the Anticancer Efficacy in MG63 Osteosarcoma Cells, Saudi J Biol Sci, 25, 10.1016/j.sjbs.2016.12.001 · DOI
  25. Maksimenko, 2003, Oligonucleotides Targeted Against a Junction Oncogene Are Made Efficient by Nanotechnologies, Pharm Res, 20, 10.1023/a:1026122914852 · DOI
  26. Sha, 2020, Exosome-Mediated Hic-5 Regulates Proliferation and Apoptosis of Osteosarcoma via Wnt/β-Catenin Signal Pathway, Aging (Albany NY), 12, 10.18632/aging.103546 · DOI
  27. Niu, 2021, Melatonin and Doxorubicin Co-Delivered via a Functionalized Graphene-Dendrimeric System Enhances Apoptosis of Osteosarcoma Cells, Mater Sci Eng C Mater Biol Appl, 119, 10.1016/j.msec.2020.111554 · DOI
  28. Qiu, 2020, Application of Tumor-Targeting Peptide-Decorated Polypeptide Nanoparticles With Doxorubicin to Treat Osteosarcoma, Drug Deliv, 27, 10.1080/10717544.2020.1856221 · DOI
  29. Li, 2019, Composition Design and Medical Application of Liposomes, Eur J Med Chem, 164, 10.1016/j.ejmech.2019.01.007 · DOI
  30. Torchilin, 2005, Recent Advances With Liposomes as Pharmaceutical Carriers, Nat Rev Drug Discovery, 4, 10.1038/nrd1632 · DOI · Paper page
  31. Mini, 2006, Cellular Pharmacology of Gemcitabine, Ann Oncol, 17, v7, 10.1093/annonc/mdj941 · DOI · Paper page
  32. Mirnejad, 2018, Clofazimine: A Useful Antibiotic for Drug-Resistant Tuberculosis, BioMed Pharmacother, 105, 10.1016/j.biopha.2018.06.023 · DOI
  33. Chen, 2018, Targeted Salinomycin Delivery With EGFR and CD133 Aptamers Based Dual-Ligand Lipid-Polymer Nanoparticles to Both Osteosarcoma Cells and Cancer Stem Cells, Nanomedicine, 14, 10.1016/j.nano.2018.05.015 · DOI
  34. Shuai, 2021, Accelerated Degradation of HAP/PLLA Bone Scaffold by PGA Blending Facilitates Bioactivity and Osteoconductivity, Bioact Mater, 6, 490, 10.1016/j.bioactmat.2020.09.001 · DOI
  35. Shuai, 2021, In Situ Synthesis of Hydroxyapatite Nanorods on Graphene Oxide Nanosheets and Their Reinforcement in Biopolymer Scaffold, J Advanced Res, 10.1016/j.jare.2021.03.009 · DOI
  36. Feng, Graphene Oxide-Driven Interfacial Coupling in Laser 3d Printed PEEK/PVA Scaffolds for Bone Regeneration, Virtual Phys Prototyping, 15, 10.1080/17452759.2020.1719457 · DOI
  37. Feng, 2019, Molybdenum Disulfide Nanosheets Embedded With Nanodiamond Particles: Co-Dispersion Nanostructures as Reinforcements for Polymer Scaffolds, Appl Mater Today, 17, 10.1016/j.apmt.2019.08.005 · DOI
  38. Despres, 2019, Mechanisms of the Immune Response Cause by Cationic and Anionic Surface Functionalized Cellulose Nanocrystals Using Cell-Based Assays, Toxicol In Vitro, 55, 10.1016/j.tiv.2018.12.009 · DOI
  39. Villegas, 2018, Nanotechnological Strategies for Protein Delivery, Molecules, 23, 10.3390/molecules23051008 · DOI
  40. Fan, 2021, Analytical Characterization of Liposomes and Other Lipid Nanoparticles for Drug Delivery, J Pharm BioMed Anal, 192, 10.1016/j.jpba.2020.113642 · DOI
  41. Mima, 2017, Ganglioside Inserted Into PEGylated Liposome Attenuates Anti-PEG Immunity, J Control Release, 250, 10.1016/j.jconrel.2017.01.040 · DOI
  42. Wu, 2020, Radioactive Polymeric Nanoparticles for Biomedical Application, Drug Deliv, 27, 10.1080/10717544.2020.1837296 · DOI
  43. Lee, 2017, Stimuli-Responsive Liposomes for Drug Delivery, Wiley Interdiscip Rev Nanomed Nanobiotechnol, 9, 10.1002/wnan.1450 · DOI
  44. Huang, 2017, Hydrogel Scaffolds for Differentiation of Adipose-Derived Stem Cells, Chem Soc Rev, 46, 10.1039/c6cs00052e · DOI
  45. Norouzi, 2016, Injectable Hydrogel-Based Drug Delivery Systems for Local Cancer Therapy, Drug Discovery Today, 21, 10.1016/j.drudis.2016.07.006 · DOI
  46. Hang, 2014, Parosteal Osteosarcoma, Arch Pathol Lab Med, 138, 10.5858/arpa.2013-0030-RS · DOI
  47. Zhao, 2020, Insight Into the Efficiency of Oxygen Introduced Photodynamic Therapy (PDT) and Deep PDT Against Cancers With Various Assembled Nanocarriers, Wiley Interdiscip Rev Nanomed Nanobiotechnol, 12, 10.1002/wnan.1583 · DOI
  48. Zou, 2020, Electrodeposition of Polysaccharide and Protein Hydrogels for Biomedical Applications, Curr Med Chem, 27, 10.2174/0929867326666191212163955 · DOI
  49. Beckett, 2020, Enhancement of the Mechanical Properties of Hydrogels With Continuous Fibrous Reinforcement, ACS Biomater Sci Eng, 6, 10.1021/acsbiomaterials.0c00911 · DOI
  50. Muxika, 2017, Chitosan as a Bioactive Polymer: Processing, Properties and Applications, Int J Biol Macromol, 105, 10.1016/j.ijbiomac.2017.07.087 · DOI
  51. Shafabakhsh, 2020, Chitosan: A Compound for Drug Delivery System in Gastric Cancer-A Review, Carbohydr Polym, 242, 10.1016/j.carbpol.2020.116403 · DOI
  52. Prati, 2015, Calcium Silicate Bioactive Cements: Biological Perspectives and Clinical Applications, Dent Mater, 31, 10.1016/j.dental.2015.01.004 · DOI
  53. Li, 2016, Magnetic Properties of Strontium Hexaferrite Nanostructures Measured With Magnetic Force Microscopy, Sci Rep, 6, 10.1038/srep25985 · DOI
  54. Wang, 2020, Chitosan Derivatives and Their Application in Biomedicine, Int J Mol Sci, 21, 10.3390/ijms21020487 · DOI
  55. Liu, 2020, Effects of Chitosan Oligosaccharide on Plasma and Hepatic Lipid Metabolism and Liver Histomorphology in Normal Sprague-Dawley Rats, Mar Drugs, 18, 10.3390/md18080408 · DOI
  56. Sekhon, 2010, Inorganic Nanomedicine–Part 2, Nanomedicine, 6, 10.1016/j.nano.2010.04.003 · DOI
  57. Erathodiyil, 2011, Functionalization of Inorganic Nanoparticles for Bioimaging Applications, Acc Chem Res, 44, 10.1021/ar2000327 · DOI
  58. Adhikari, 2020, Correction: Manganese Neurotoxicity: Nano-Oxide Compensates for Ion-Damage in Mammals, Biomater Sci, 8, 10.1039/d0bm90070b · DOI
  59. Zhao, 2020, Advances in Template Prepared Nano-Oxides and Their Applications: Polluted Water Treatment, Energy, Sensing and Biomedical Drug Delivery, Chem Rec, 20, 10.1002/tcr.201900093 · DOI
  60. Shi, 2020, Near-Infrared Laser-Induced Phase-Shifted Nanoparticles for US/MRI-Guided Therapy for Breast Cancer, Colloids Surf B Biointerfaces, 196, 10.1016/j.colsurfb.2020.111278 · DOI
  61. Wang, 2017, Super-Light Cu@Ni Nanowires/Graphene Oxide Composites for Significantly Enhanced Microwave Absorption Performance, Sci Rep, 7, 1584, 10.1038/s41598-017-01529-2 · DOI
  62. Xiong, 2016, Magnetic Core-Shell Silica Nanoparticles With Large Radial Mesopores for siRNA Delivery, Small, 12, 10.1002/smll.201600531 · DOI
  63. Puiu, 2021, Anti-Cancer Nanopowders and MAPLE-Fabricated Thin Films Based on SPIONs Surface Modified With Paclitaxel Loaded β-Cyclodextrin, Pharmaceutics, 13, 1356, 10.3390/pharmaceutics13091356 · DOI
  64. Gisbert-Garzarán, 2020, Mesoporous Silica Nanoparticles for Targeting Subcellular Organelles, Int J Mol Sci, 21, 9696, 10.3390/ijms21249696 · DOI
  65. Lu, 2018, Enhancing Osteosarcoma Killing and CT Imaging Using Ultrahigh Drug Loading and NIR-Responsive Bismuth Sulfide@Mesoporous Silica Nanoparticles, Adv Healthc Mater, 7, 10.1002/adhm.201800602 · DOI
  66. Hu, 2021, Amplification of Oxidative Stress With Lycorine and Gold-Based Nanocomposites for Synergistic Cascade Cancer Therapy, J Nanobiotechnol, 19, 221, 10.1186/s12951-021-00933-1 · DOI
  67. Nuthalapati, 2020, Highly Sensitive, Scalable Reduced Graphene Oxide With Palladium Nano-Composite as Strain Sensor, Nanotechnology, 31, 10.1088/1361-6528/ab4855 · DOI
  68. Zhuang, 2019, Three-Dimensional-Printed Bioceramic Scaffolds With Osteogenic Activity for Simultaneous Photo/Magnetothermal Therapy of Bone Tumors, ACS Biomater Sci Eng, 5, 10.1021/acsbiomaterials.9b01095 · DOI
  69. Su, 2020, Graphene Oxide Coated Titanium Surfaces With Osteoimmunomodulatory Role to Enhance Osteogenesis, Mater Sci Eng C Mater Biol Appl, 113, 10.1016/j.msec.2020.110983 · DOI
  70. Kim, 2020, Engineered Metal Oxide Nanomaterials Inhibit Corneal Epithelial Wound Healing In Vitro and In Vivo, NanoImpact, 17, 10.1016/j.impact.2019.100198 · DOI
  71. Sun, 2020, Recent Progress of SERS Optical Nanosensors for miRNA Analysis, J Mater Chem B, 8, 10.1039/d0tb00280a · DOI
  72. Fu, 2014, Mechanisms of Nanotoxicity: Generation of Reactive Oxygen Species, J Food Drug Anal, 22, 64, 10.1016/j.jfda.2014.01.005 · DOI
  73. Nassar, 2016, Cancer Stem Cells: Basic Concepts and Therapeutic Implications, Annu Rev Pathol, 11, 47, 10.1146/annurev-pathol-012615-044438 · DOI
  74. Shi, 2019, LncRNA AFAP1-AS1 Promotes Tumorigenesis and Epithelial-Mesenchymal Transition of Osteosarcoma Through RhoC/ROCK1/p38MAPK/Twist1 Signaling Pathway, J Exp Clin Cancer Res, 38, 375, 10.1186/s13046-019-1363-0 · DOI
  75. Li, 2019, FGF-Induced LHX9 Regulates the Progression and Metastasis of Osteosarcoma via FRS2/TGF-β/β-Catenin Pathway, Cell Div, 14, 10.1186/s13008-019-0056-6 · DOI
  76. Negri, 2020, Carbon Nanotubes in Biomedicine, Top Curr Chem (Cham), 378, 15, 10.1007/s41061-019-0278-8 · DOI
  77. Zhang, 2017, Bioinspired “Active” Stealth Magneto-Nanomicelles for Theranostics Combining Efficient MRI and Enhanced Drug Delivery, ACS Appl Mater Interfaces, 9, 10.1021/acsami.7b10086 · DOI
  78. Li, 2020, Polyion Complex Micelles for Protein Delivery Benefit From Flexible Hydrophobic Spacers in the Binding Group, Macromol Rapid Commun, 41, 10.1002/marc.202000208 · DOI
  79. Chauhan, 2018, Dendrimers for Drug Delivery, Molecules, 23, 10.3390/molecules23040938 · DOI
  80. Palmerston Mendes, 2017, Dendrimers as Nanocarriers for Nucleic Acid and Drug Delivery in Cancer Therapy, Molecules, 22, 10.3390/molecules22091401 · DOI · Paper page
  81. Ziemba, 2012, Influence of Dendrimers on Red Blood Cells, Cell Mol Biol Lett, 17, 21, 10.2478/s11658-011-0033-9 · DOI
  82. Bertero, 2014, Surface Functionalisation Regulates Polyamidoamine Dendrimer Toxicity on Blood-Brain Barrier Cells and the Modulation of Key Inflammatory Receptors on Microglia, Nanotoxicology, 8, 10.3109/17435390.2013.765054 · DOI
  83. Liu, 2021, Dendronized Arm Snowflake Polymer as a Highly Branched Scaffold for Cellular Imaging and Delivery, Biomacromolecules, 22, 10.1021/acs.biomac.1c00631 · DOI
  84. Somiya, 2015, Development of a Virus-Mimicking Nanocarrier for Drug Delivery Systems: The Bio-Nanocapsule, Adv Drug Delivery Rev, 95, 77, 10.1016/j.addr.2015.10.003 · DOI
  85. Zalupski, 1988, Ifosfamide, J Natl Cancer Inst, 80, 10.1093/jnci/80.8.556 · DOI
  86. Bennett, 2019, Therapeutic Antisense Oligonucleotides Are Coming of Age, Annu Rev Med, 70, 10.1146/annurev-med-041217-010829 · DOI
  87. Zhang, 2019, Exosomes in Cancer Development, Metastasis, and Immunity, Biochim Biophys Acta Rev Cancer, 1871, 10.1016/j.bbcan.2019.04.004 · DOI · Paper page
  88. Gong, 2018, Exosomal miR-675 From Metastatic Osteosarcoma Promotes Cell Migration and Invasion by Targeting Caln1, Biochem Biophys Res Commun, 500, 10.1016/j.bbrc.2018.04.016 · DOI
  89. Maroto, 2017, Effects of Storage Temperature on Airway Exosome Integrity for Diagnostic and Functional Analyses, J Extracell Vesicles, 6, 10.1080/20013078.2017.1359478 · DOI · Paper page
  90. Danhier, 2010, To Exploit the Tumor Microenvironment: Passive and Active Tumor Targeting of Nanocarriers for Anti-Cancer Drug Delivery, J Control Release, 148, 10.1016/j.jconrel.2010.08.027 · DOI
  91. Donahue, 2019, Concepts of Nanoparticle Cellular Uptake, Intracellular Trafficking, and Kinetics in Nanomedicine, Adv Drug Delivery Rev, 143, 68, 10.1016/j.addr.2019.04.008 · DOI
  92. Amreddy, 2018, Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery, Adv Cancer Res, 137, 10.1016/bs.acr.2017.11.003 · DOI
  93. González-Fernández, 2017, Doxorubicin and Edelfosine Lipid Nanoparticles Are Effective Acting Synergistically Against Drug-Resistant Osteosarcoma Cancer Cells, Cancer Lett, 388, 10.1016/j.canlet.2016.12.012 · DOI
  94. Kaldybekov, 2019, Maleimide-Functionalised PLGA-PEG Nanoparticles as Mucoadhesive Carriers for Intravesical Drug Delivery, Eur J Pharm Biopharm, 143, 24, 10.1016/j.ejpb.2019.08.007 · DOI
  95. Amin, 2018, Untemplated Resveratrol-Mediated Polydopamine Nanocapsule Formation, ACS Appl Mater Interfaces, 10, 10.1021/acsami.8b14128 · DOI
  96. Li, 2017, Cancer Drug Delivery in the Nano Era: An Overview and Perspectives (Review), Oncol Rep, 38, 10.3892/or.2017.5718 · DOI
  97. Fodjo, 2017, Selective Synthesis of Fe(3)O(4)Au (X) Ag (Y) Nanomaterials and Their Potential Applications in Catalysis and Nanomedicine, Chem Cent J, 11, 58, 10.1186/s13065-017-0288-y · DOI
  98. Piscatelli, 2021, Complex Factors and Challenges That Affect the Pharmacology, Safety and Efficacy of Nanocarrier Drug Delivery Systems, Pharmaceutics, 13, 114, 10.3390/pharmaceutics13010114 · DOI
  99. Wang, 2020, Recent Advances of Drug Delivery Nanocarriers in Osteosarcoma Treatment, J Cancer, 11, 69, 10.7150/jca.36588 · DOI
  100. Kim, 2021, Recent Advances in Exosome-Based Drug Delivery for Cancer Therapy, Cancers (Basel), 13, 4435, 10.3390/cancers13174435 · DOI · Paper page

Cited by

Sorted by citations

See all 39

Metadata

Authors
Wu, K., Yu, B., Li, D., Tian, Y., Liu, Y., & Jiang, J.
Venue
Frontiers in Oncology
Publisher
Frontiers Media SA
Published
2022-02-15
Volume
12
ISSN
2234-943X
DOI
10.3389/fonc.2022.805978
PMC
PMC8885548
Cited by
39
References
5
Licence
creativecommons.org/licenses/by/4.0/ (vor)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Recent Advances in Nanoplatforms for the Treatment of Osteosarcoma. https://app.cochat.ai/papers/10.3389/fonc.2022.805978
The paper
Wu, K., Yu, B., Li, D., Tian, Y., Liu, Y., & Jiang, J. (2022). Recent Advances in Nanoplatforms for the Treatment of Osteosarcoma. Frontiers in Oncology. https://doi.org/10.3389/fonc.2022.805978