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The multiple roles of fatty acid handling proteins in brain
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FABP7-dependent trafficking is required for biosynthesis of eCBs from PUFAs and for their delivery to nuclear PPARs for regulation of gene transcription.
“FABP7-dependent trafficking is required for biosynthesis of eCBs from PUFAs, and for their delivery to nuclear PPARs for regulation of gene transcription53–56.”
From Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel (2025) · cites this paper as [56]
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The blood-brain barrier/neurovascular unit in health and disease
Hawkins, B. T., & Davis, T. P. (2005) · Pharmacological Reviews · doi:10.1124/pr.57.2.4 · Cited by 2,661
Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40
Itoh, Y., Kawamata, Y., Harada, M., Kobayashi, M., Fujii, R., Fukusumi, S., Ogi, K., Hosoya, M., Tanaka, Y., Uejima, H., et al. (2003) · Nature · doi:10.1038/nature01478 · Cited by 1,538
Stewart, C. R., Stuart, L. M., Wilkinson, K., van Gils, J. M., Deng, J., Halle, A., Rayner, K. J., Boyer, L., Zhong, R., Frazier, W. A., et al. (2010) · Nature Immunology · doi:10.1038/ni.1836 · Cited by 1,513
Obici, S., Feng, Z., Arduini, A., Conti, R., & Rossetti, L. (2003) · Nature Medicine · doi:10.1038/nm873 · Cited by 548
Obesity and Hypertriglyceridemia Produce Cognitive Impairment
Farr, S. A., Yamada, K. A., Butterfield, D. A., Abdul, H. M., Xu, L., Miller, N. E., Banks, W. A., & Morley, J. E. (2008) · Endocrinology · doi:10.1210/en.2007-1722 · Cited by 382
Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing
Le Foll, C., Irani, B. G., Magnan, C., Dunn-Meynell, A. A., & Levin, B. E. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00223.2009 · Cited by 159 · cited 3×
“…et al., 2009). www.frontiersin.org September 2012 | Volume 3 | Article 385 | 3 In addition, studies suggest that hypothalamic FA sensitive neurons are dependent on the metabolic state and display different responses during fasting versus overfed state (Le Foll et al., 2009; Migrenne et al., 2011).”
BackgroundPark, L., Wang, G., Zhou, P., Zhou, J., Pitstick, R., Previti, M. L., Younkin, L., Younkin, S. G., Van Nostrand, W. E., Cho, S., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015413108 · Cited by 156
Fatty Acid Binding Protein: Localization and Functional Significance in the Brain
Owada, Y. (2008) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.214.213 · Cited by 122
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Metadata
- Authors
- Moullé, V. S. F., Cansell, C., Luquet, S., & Cruciani-Guglielmacci, C.
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2012
- Volume
- 3
- ISSN
- 1664-042X
- PMC
- PMC3460233
- Cited by
- 49
- References
- 8
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