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Hepcidin and Anemia: A Tight Relationship
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“Hepcidin, recognized as a central regulator of iron metabolism, limits intestinal Fe absorption and its release from body stores, primarily from the liver and macrophages56,57.”
From Impact of a single swimming session on inflammatory response and iron homeostasis in adolescent female athletes during the luteal phase (2025) · cites this paper as [56]
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Cites
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
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Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
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Self-citationAngiocrine Bmp2 signaling in murine liver controls normal iron homeostasis
Koch, P.-S., Olsavszky, V., Ulbrich, F., Sticht, C., Demory, A., Leibing, T., Henzler, T., Meyer, M., Zierow, J., Schneider, S., et al. (2017) · Blood · doi:10.1182/blood-2016-07-729822 · Cited by 161
Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6
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Pharmacological Targeting of the Hepcidin/Ferroportin Axis
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A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome
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Self-citationNormalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency
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Cited by
Chaudhary, E., George, F., Saji, A., Dey, S., Ghosh, S., Thomas, T., Kurpad, A. V., Sharma, S., Singh, N., Agarwal, S., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-42709-1 · Cited by 92
Immune Mechanisms in Inflammatory Anemia
Canny, S. P., Orozco, S. L., Thulin, N. K., & Hamerman, J. A. (2023) · Annual Review of Immunology · doi:10.1146/annurev-immunol-101320-125839 · Cited by 65
Girardi, A. C. C., Polidoro, J. Z., Castro, P. C., Pio-Abreu, A., Noronha, I. L., & Drager, L. F. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00143.2024 · Cited by 32
Mydłowska, M., Kasperska, A., Cichoń-Woźniak, J., Dziewiecka, H., Ostapiuk-Karolczuk, J., & Skarpańska-Stejnborn, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-29551-9 · Cited by 2
Metadata
- Authors
- Pagani, A., Nai, A., Silvestri, L., & Camaschella, C.
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2019-10-09
- Volume
- 10
- ISSN
- 1664-042X
- Cited by
- 223
- References
- 17
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