Cited by 22Eating Disorders and BehaviorsNutrition, Health and Food BehaviorChild Nutrition and Feeding Issues

The Neuropsychological Profile of Severe and Enduring Anorexia Nervosa: A Systematic Review

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Broomfield, Catherine, Stedal, Kristin, Touyz, Stephen·2021·Frontiers in Psychology

Abstract

Characteristics of Severe and Enduring Anorexia Nervosa (SE-AN) are being investigated to differentiate the patients experiencing SE-AN from those at earlier stages of the AN disease. The current systematic review was the first step in exploring neuropsychological functioning as a potentially identifying characteristic for long-term presentations. With a subgroup of AN patients reflecting a unique neuropsychological profile that is proportionate to the quantity of patients that go on to develop SE-AN, it was the aim of this review to assess neuropsychological functioning in the later stage of the disease. In accordance with PRISMA guidelines, a literature search was conducted using four electronic databases (PsycINFO, MEDLINE, Web of Science, and Scopus) for neuropsychological research on AN participants with a seven or more year illness duration. Datasets that met inclusion criteria were screened for SE-AN participants ( N = 166) and neuropsychological data extracted together with potentially confounding variables and information required to conduct a quality assessment. In research investigating decision-making, participants with a SE-AN presentation demonstrated significantly lower functioning compared to healthy controls. There was conflicting evidence for differences in intellectual functioning and set-shifting abilities with no variability indicated in central coherence, memory, attention, reasoning, or processing speed. If findings from this preliminary analysis are confirmed through empirical research, implications include earlier identification of SE-AN patients and more effective treatment development.

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  1. Cohen J. (1969). Statistical Power Analysis in the Behavioural Sciences. New York, NY: Academic Press.
  2. Franko D. L. Murray H. B. Mancuso C. J. Eddy K. T. (2016). Quality of life and psychosocial functioning in severe and enduring anorexia nervosa, in Managing Severe and Enduring Anorexia Nervosa, eds Touyz S. Le Grange D. Lacey J. H. Haypp P. (New York, NY: Routledge), 13– 27.
  3. Utzinger L. M. Haynos A. F. Wonderlich S. A. Crosby R. D. Le Grange D. Hay P.. (2016). Empirical classification of severe and enduring anorexia nervosa: effects on social and emotional functioning, in Poster session presented at: International Conference on Eating Disorders (San Francisco, CA).

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Authors
Broomfield, C., Stedal, K., & Touyz, S.
Affiliations
  • The University of Sydney (AU)
  • Oslo University Hospital (NO)
Corresponding author
Broomfield, Catherine
Venue
Frontiers in Psychology
Published
2021-08-02
Volume
12
Pages
708536-708536
ISSN
1664-1078 (ISSN-L)
OpenAlex
W3191436965
Cited by
22
References
119
Citations by year
2026: 5 · 2025: 4 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 1
FWCI
0.43
Type
journal article
Language
en
Open access
Locations
  • Frontiers in Psychology (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
University of Sydney
Topics
  • Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
  • Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords
severe and enduring anorexia nervosa, neuropsychological performance, decision-making, intellectual functioning, set-shifting, central coherence, memory, attention, processing speed

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