Neurofunctional underpinnings of audiovisual emotion processing in teens with autism spectrum disorders
Open accessAbstract
Despite successful performance on some audiovisual emotion tasks, hypoactivity has been observed in frontal and temporal integration cortices in individuals with autism spectrum disorders (ASD). Little is understood about the neurofunctional network underlying this ability in individuals with ASD. Research suggests that there may be processing biases in individuals with ASD, based on their ability to obtain meaningful information from the face and/or the voice. This functional magnetic resonance imaging study examined brain activity in teens with ASD (n = 18) and typically developing controls (n = 16) during audiovisual and unimodal emotion processing. Teens with ASD had a significantly lower accuracy when matching an emotional face to an emotion label. However, no differences in accuracy were observed between groups when matching an emotional voice or face-voice pair to an emotion label. In both groups brain activity during audiovisual emotion matching differed significantly from activity during unimodal emotion matching. Between-group analyses of audiovisual processing revealed significantly greater activation in teens with ASD in a parietofrontal network believed to be implicated in attention, goal-directed behaviors, and semantic processing. In contrast, controls showed greater activity in frontal and temporal association cortices during this task. These results suggest that in the absence of engaging integrative emotional networks during audiovisual emotion matching, teens with ASD may have recruited the parietofrontal network as an alternate compensatory system.
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Both adolescents with ASD and typically developing peers show greater activation in multisensory than unisensory conditions.
“Although both teens with ASD and their TD peers showed greater activation in the multisensory condition compared to the unisensory condition”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Doyle-Thomas et al., 2013
In adolescents with ASD, performance is impaired for correctly identifying emotional faces in a visual-only condition.
“teens with ASD were impaired at correctly identifying emotional faces (visual only condition)”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Doyle-Thomas et al., 2013
In adolescents with ASD, performance is intact for face/voice pairs in an audiovisual condition.
“and face/voice pairs (audiovisual condition; Doyle-Thomas et al., 2013)”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Doyle-Thomas et al., 2013
In adolescents with ASD, performance is intact for emotional voices in an auditory-only condition.
“showed intact performance for emotional voices (auditory only condition)”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Doyle-Thomas et al., 2013
Individuals with ASD activate a different network than typically developing individuals during an emotion-labeling task.
“individuals with ASD seemed to activate a different network than the individuals with TD”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Doyle-Thomas et al., 2013
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- Authors
- Doyle-Thomas, K. A. R., Goldberg, J., Szatmari, P., & Hall, G. B. C.
- Affiliations
- St. Joseph’s Healthcare Hamilton (CA)
- McMaster University (CA)
- Corresponding author
- Hall, Geoffrey B.C.
- ORCID
- Hall, Geoffrey B.C.
- Venue
- Frontiers in Psychiatry
- Publisher
- Frontiers Media SA
- Published
- 2013
- Volume
- 4
- Pages
- 48-48
- ISSN
- 1664-0640 (ISSN-L)
- PMC
- PMC3667547
- OpenAlex
- W2150313880
- Cited by
- 25
- References
- 41
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 2 · 2018: 5 · 2017: 3 · 2016: 2 · 2015: 2 · 2014: 3
- FWCI
- 1.28
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Psychiatry (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Keywords
- autism spectrum disorder, emotion recognition, face-voice integration, adolescents, compensatory neural recruitment
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