The DOI matches its Crossref record; 213 of the 215 references it cites were found in a registry or an index.
Beyond the GFAP-Astrocyte Protein Markers in the Brain
Open accessAbstract
The idea of central nervous system as one-man band favoring neurons is long gone. Now we all are aware that neurons and neuroglia are team players and constant communication between those various cell types is essential to maintain functional efficiency and a quick response to danger. Here, we summarize and discuss known and new markers of astroglial multiple functions, their natural heterogeneity, cellular interactions, aging and disease-induced dysfunctions. This review is focused on newly reported facts regarding astrocytes, which are beyond the old stereotypes. We present an up-to-date list of marker proteins used to identify a broad spectrum of astroglial phenotypes related to the various physiological and pathological nervous system conditions. The aim of this review is to help choose markers that are well-tailored for specific needs of further experimental studies, precisely recognizing differential glial phenotypes, or for diagnostic purposes. We hope it will help to categorize the functional and structural diversity of the astroglial population and ease a clear readout of future experimental results.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Many of the genes whose expression increased the most with age are selectively expressed by astrocytes.49”
From Uncovering the signatures of aging and senescence in the human dorsolateral prefrontal cortex (2026) · cites this paper as [49]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Glutamate neurotoxicity and diseases of the nervous system
Choi, D. W. (1988) · Neuron · doi:10.1016/0896-6273(88)90162-6 · Cited by 8,188
Neurotoxic reactive astrocytes are induced by activated microglia
Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W.-S., Peterson, T. C., et al. (2017) · Nature · doi:10.1038/nature21029 · Cited by 7,971
Astrocyte-endothelial interactions at the blood-brain barrier
Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595
Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875 · cited 1×
“Analysis of transcriptome demonstrated that PDK4 expression is 30 times higher in astrocytes than in neurons [56].”
BackgroundCahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
Zeisel, A., Muñoz-Manchado, A. B., Codeluppi, S., Lönnerberg, P., La Manno, G., Juréus, A., Marques, S., Munguba, H., He, L., Betsholtz, C., et al. (2015) · Science · doi:10.1126/science.aaa1934 · Cited by 3,124
Cellular Scaling Rules for the Brains of Marsupials: Not as “Primitive” as Expected
Santos, S. E. D., Porfírio, J., Cunha, F., Manger, P. R., Tavares, W. C., Pessôa, L. M., Raghanti, M. A., Sherwood, C. C., & Herculano‐Houzel, S. (2017) · Brain Behavior and Evolution · doi:10.1159/000452856 · Cited by 2,652
Single-cell transcriptomic analysis of Alzheimer’s disease
Mathys, H., Davila-Velderrain, J., Peng, Z., Gao, F., Mohammadi, S., Young, J. Z., Menon, M., He, L., Abdurrob, F., Jiang, X., et al. (2019) · Nature · doi:10.1038/s41586-019-1195-2 · Cited by 2,568
Reactive astrocyte nomenclature, definitions, and future directions
Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-020-00783-4 · Cited by 2,513 · cited 3×
“Unfortunately, current knowledge does not allow proposing definitive categorization in this matter yet [97,101].”
BackgroundGenomic analysis of reactive astrogliosis
Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., & Barres, B. A. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6221-11.2012 · Cited by 2,404
Cited by
Sorted by citations
GFAP as a Potential Biomarker for Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Kim, K. Y., Shin, K. Y., & Chang, K.-A. (2023) · Cells · doi:10.3390/cells12091309 · Cited by 309
Calcium signaling in astrocytes and gliotransmitter release
Goenaga, J. G., Araque, A., Kofuji, P., & Chao, D. H. M. (2023) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2023.1138577 · Cited by 160
Astrocytes in Chronic Pain: Cellular and Molecular Mechanisms
Lu, H.-J., & Gao, Y.-J. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-022-00961-3 · Cited by 118
Scalfari, A., Traboulsee, A. L., Oh, J., Airas, L. M., Bittner, S., Calabrese, M., García‐Domínguez, J. M., Granziera, C., Greenberg, B. M., Hellwig, K., et al. (2024) · Annals of Neurology · doi:10.1002/ana.27034 · Cited by 107
Astrocyte-Mediated Neuroinflammation in Neurological Conditions
Zhao, Y., Huang, Y., Cao, Y., & Yang, J. H. (2024) · Biomolecules · doi:10.3390/biom14101204 · Cited by 106
Heneka, M. T., Gauthier, S. G., Chandekar, S. A., Hahn-Pedersen, J. H., Bentsen, M. A., & Zetterberg, H. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02939-9 · Cited by 97
Guardia, G. S., Custers, E., de Lange, A., Clijncke, E., Geenen, B., Gutierrez, J., Küsters, B., Claassen, J. A. H. R., de Leeuw, F., Wiesmann, M., et al. (2023) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01497-3 · Cited by 72
Molecular Mechanisms Underlying Neuroinflammation Elicited by Occupational Injuries and Toxicants
Pathak, D., & Sriram, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032272 · Cited by 72
The Similar and Distinct Roles of Satellite Glial Cells and Spinal Astrocytes in Neuropathic Pain
McGinnis, A., & Ji, R. (2023) · Cells · doi:10.3390/cells12060965 · Cited by 67
Guise, A. J., Misal, S. A., Carson, R. H., Chu, J.-H., Boekweg, H., Watt, D. V. D., Welsh, N. C., Truong, T., Liang, Y., Xu, S., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2023.113636 · Cited by 63
Marcellus, K. A., Bugiel, S., Nunnikhoven, A., Curran, I. H., & Gill, S. (2024) · Nanomaterials · doi:10.3390/nano14050429 · Cited by 58
Hubbard, W. B., Velmurugan, G. V., Brown, E., & Sullivan, P. G. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01395-8 · Cited by 51
Prefrontal cortex astroglia modulate anhedonia-like behavior
Codeluppi-Arrowsmith, S. A., Xu, M., Bansal, Y., Lepack, A. E., Duric, V., Chow, M., Muir, J., Bagot, R. C., Licznerski, P., Wilber, S. L., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02246-1 · Cited by 45
Neurodegenerative Diseases: Unraveling the Heterogeneity of Astrocytes
Santiago-Balmaseda, A., Aguirre-Orozco, A., Valenzuela-Arzeta, I. E., Villegas-Rojas, M. M., Pérez‐Segura, I., Jiménez-Barrios, N., Hurtado-Robles, E., Rodríguez-Hernández, L. D., Rivera-German, E. R., Guerra‐Crespo, M., et al. (2024) · Cells · doi:10.3390/cells13110921 · Cited by 43
Microglia-induced neuroinflammation in hippocampal neurogenesis following traumatic brain injury
Navabi, S. P., Badreh, F., Shooshtari, M. K., Hajipour, S., Vastegani, S. M., & Khoshnam, S. E. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35869 · Cited by 42
Yang, R., Yang, J., Li, Z., Su, R., Zou, L., Li, L., Xu, X., Li, G., Liu, S., Liang, S., et al. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03023-x · Cited by 39
High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy
Pai, B., Tomé-García, J., Cheng, W. S., Nudelman, G., Beaumont, K. G., Ghatan, S., Panov, F. E., Caballero, E., Sarpong, K., Marcuse, L. V., et al. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01453-1 · Cited by 38
Brain Metabolism in Health and Neurodegeneration: The Interplay Among Neurons and Astrocytes
Shichkova, P., Coggan, J. S., Markram, H., & Keller, D. X. (2024) · Cells · doi:10.3390/cells13201714 · Cited by 39
A 3D Bioprinted Human Neurovascular Unit Model of Glioblastoma Tumor Growth
Tung, Y., Chen, Y., Derr, K., Wilson, K. M., Song, M. J., & Ferrer, M. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202302831 · Cited by 34
Geng, Y., Qiu, L., Cheng, Y., Li, J., Ma, Y., Zhao, C., Cai, Y., Zhang, X., Chen, J., Pan, Y., et al. (2024) · Advanced Science · doi:10.1002/advs.202309517 · Cited by 33
Xu, Y., Wang, S., Feng, Q., Xia, J., Li, Y., Li, H., & Wang, J. (2024) · Nature Communications · doi:10.1038/s41467-024-51891-9 · Cited by 35
Distribution Patterns of Astrocyte Populations in the Human Cortex
Forrest, S. L., Kim, J. H., Crockford, D. R., Huynh, K., Cheong, R., Knott, S., Kane, M. A., Ittner, L. M., Halliday, G. M., & Kril, J. J. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03700-2 · Cited by 34
王学文, Kang, J., Li, X., Wu, P., Huang, Y., Huang, Y., Feng, J., & Feng, J. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118016 · Cited by 30
Role of Glial Cells in Neuronal Function, Mood Disorders, and Drug Addiction
Tizabi, Y., Getachew, B., Hauser, S. R., Tsytsarev, V., Manhães, A. C., & da Silva, V. D. A. (2024) · Brain Sciences · doi:10.3390/brainsci14060558 · Cited by 27
Astrocytes and Alpha-Synuclein: Friend or Foe?
Ozoran, H., & Srinivasan, R. (2023) · Journal of Parkinson s Disease · doi:10.3233/jpd-230284 · Cited by 28
Paidlewar, M., Kumari, S., Dhapola, R., Sharma, P., & HariKrishnaReddy, D. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112940 · Cited by 27
Bansal, Y., Codeluppi-Arrowsmith, S. A., & Banasr, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126357 · Cited by 25
PI3K/AKT pathway: A potential therapeutic target in cerebral ischemia-reperfusion injury
Han, Y., Sun, Y., Peng, S., Tang, T., Zhang, B., Yu, R., Sun, X., Guo, S., Ma, L., Li, P., et al. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177505 · Cited by 27
Blood-brain barrier biomarkers
Zapata-Acevedo, J. F., Mantilla-Galindo, A., Vargas-Sánchez, K., & González-Reyes, R. E. (2024) · Advances in clinical chemistry · doi:10.1016/bs.acc.2024.04.004 · Cited by 23
Dinkel, L., Hummel, S., Zenatti, V., Malara, M., Tillmann, Y., Colombo, A., Monasor, L. S., Suh, J. H., Logan, T., Roth, S., et al. (2024) · Science Translational Medicine · doi:10.1126/scitranslmed.adl4616 · Cited by 22
The rise of astrocytes: are they guardians or troublemakers of the brain disorder?
Kim, H. Y., Kim, S., Akaydin, A. N., Kim, S. S., Hyeon, S. J., Lee, J.-H., & Ryu, H. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-025-01627-6 · Cited by 28
Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations
Hua, L. H., Solomon, A. J., Tenembaum, S. N., Scalfari, A., Rovira, À., Rostasy, K. M., Newsome, S. D., Marrie, R. A., Magyari, M., Kantarci, O. H., et al. (2024) · JAMA Neurology · doi:10.1001/jamaneurol.2024.3062 · Cited by 23
Kim, S., Oh, H., Choi, S. H., Yoo, Y.-E., Noh, Y. W., Cho, Y., Im, G. H., Lee, C., Oh, Y., Yang, E., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111398 · Cited by 21
Astroglial Cells: Emerging Therapeutic Targets in the Management of Traumatic Brain Injury
Czyżewski, W., Mazurek, M., Sakwa, L., Szymoniuk, M., Pham, J., Pasierb, B., Litak, J., Czyżewska, E., Turek, M., Piotrowski, B., et al. (2024) · Cells · doi:10.3390/cells13020148 · Cited by 22
Spatiotemporal dynamics of 5-HT6 receptor ciliary localization during mouse brain development
Dupuy, V., Prieur, M., Pizzoccaro, A., Margarido, C., Valjent, E., Bockaert, J., Bouschet, T., Marin, P., & Chaumont-Dubel, S. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105949 · Cited by 19
Mantecón‐Oria, M., Tapia, O., Lafarga, M., Berciano, M. T., Munuera, J., Villar-Rodil, S., Paredes, J. I., Rivero, M. J., Diban, N., & Urtiaga, A. M. (2022) · Scientific Reports · doi:10.1038/s41598-022-17697-9 · Cited by 20
Oh, H., & Kim, W. (2023) · Scientific Reports · doi:10.1038/s41598-023-49740-8 · Cited by 19
The janus face of astrocytes in multiple sclerosis: Balancing protection and pathology
Abulaban, A. A., Al-Kuraishy, H. M., Al-Gareeb, A. I., Albuhadily, A. K., Shokr, M. M., Alexiou, A. T., Papadakis, M., & Batiha, G. E. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111356 · Cited by 20
Baassiri, M. G. E., Rahal, S. S., Fulton, W. B., Sodhi, C. P., Hackam, D. J., & Nasr, I. W. (2023) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000003887 · Cited by 18
Are cytoskeleton changes observed in astrocytes functionally linked to aging?
Villablanca, C., Vidal, R. L., & González-Billault, C. E. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.03.007 · Cited by 19
Ferguson, B. J., & Gresshoff, P. M. (2009) · Cited by 18
BML-281 promotes neuronal differentiation by modulating Wnt/Ca2+ and Wnt/PCP signaling pathway
Choi, J., Gang, S., Ramalingam, M., Hwang, J., Jeong, H., Yoo, J., Cho, H., Kim, B. C., Jang, S., Jeong, H., et al. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04857-2 · Cited by 17
Veje, M., Griška, V., Pakalnienė, J., Mickienė, A., Bremell, D., Zetterberg, H., Blennow, K., Lindquist, L., & Studahl, M. (2023) · European Journal of Neurology · doi:10.1111/ene.15978 · Cited by 16
Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells
Ciarpella, F., Zamfir, R. G., Campanelli, A., Pedrotti, G., Chio, M. D., Bottani, E., & Decimo, I. (2023) · STAR Protocols · doi:10.1016/j.xpro.2023.102413 · Cited by 17
Schenck, J. K., Karl, M. T., Paredes, C. C., Bastin, A., Pushkarsky, T., Břicháček, B., Miller, R. H., & Bukrinsky, M. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03124-5 · Cited by 16
The Dual Role of Astrocytes in CNS Homeostasis and Dysfunction
Tiwari, A., Rout, S., Deep, P., Sahu, C., & Samal, P. K. (2025) · Neuroglia · doi:10.3390/neuroglia6040038 · Cited by 18
Levy-Myers, R., Daudelin, D., Na, C. H., & Sockanathan, S. (2023) · Science Advances · doi:10.1126/sciadv.adg2067 · Cited by 15
Engineering circuits of human iPSC-derived neurons and rat primary glia
Girardin, S., Ihle, S. J., Menghini, A., Krubner, M., Tognola, L., Duru, J., Fruh, I., Fruh, I., Müller, M., & Vörös, J. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1103437 · Cited by 12
Behroozi, Z., Rahimi, B., Motamednezhad, A., Ghadaksaz, A., Hormozi‐Moghaddam, Z., Moshiri, A., Jafarpour, M., Hajimirzaei, P., Ataie, A., & Janzadeh, A. (2024) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-023-00501-6 · Cited by 14
Ortiz, C., Pearson, A., McCartan, R., Roche, S., Carothers, N., Browning, M., Perez, S. E., He, B., Ginsberg, S. D., MULLAN, M. J., et al. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03117-4 · Cited by 14
Neuronal differentiation requires BRAT1 complex to remove REST from chromatin
Dokaneheifard, S., Santos, H. G. D., Valencia, M. G., Harikumar, A., Edupuganti, R. R., & Shiekhattar, R. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2318740121 · Cited by 13
Hashemi, P., Mardani, P., Raz, Z. E., Saedi, A., Fatahi, E., Izapanah, E., & Ahmadi, S. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04407-x · Cited by 14
Lanciotti, A., Brignone, M. S., Macioce, P., Visentin, S., & Ambrosini, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010274 · Cited by 14
Diminished LC3-Associated Phagocytosis by Huntington’s Disease Striatal Astrocytes
Wakida, N. M., Lau, A., Nguyen, J., Cruz, G. M. S., Fote, G., Steffan, J. S., Thompson, L. M., & Berns, M. W. (2022) · Journal of Huntington s Disease · doi:10.3233/jhd-210502 · Cited by 17
Vogtmann, R., Burk, L. V., Serdar, M., Kimmig, R., Bendix, I., & Gellhaus, A. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3024032 · Cited by 15
Yang, M., Jia, M., Cai, M., Feng, X., Huang, L., & Yang, J. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06840-9 · Cited by 16
Role of astrocytes in the pathogenesis of perinatal brain injury
Li, L., Cui, X., Zhu, B., Zhou, L., Guo, Y., Liu, T., & Shi, Y. (2025) · Molecular Medicine · doi:10.1186/s10020-025-01328-w · Cited by 16
Piavchenko, G. A., Soldatov, V. O., Venediktov, A. A., Kartashkina, N. L., Novikova, N. S., Gorbunova, M., Boronikhina, T. V., Yatskovskiy, A. N., Meglinski, I. V., & Kuznetsov, S. L. (2022) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2022.940993 · Cited by 13
Park, B., & Choi, G. E. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102786 · Cited by 13
Soubannier, V., Chaineau, M., Gursu, L., Haghi, G., Franco-Flores, A. K., Rouleau, G. A., Durcan, T. M., & Stifani, S. (2022) · Cells · doi:10.3390/cells11030399 · Cited by 12
Astrocytes in the Neuropathology of Bipolar Disorder: Review of Current Evidence
Dai, N., Jones, B. D. M., & Husain, M. I. (2022) · Brain Sciences · doi:10.3390/brainsci12111513 · Cited by 15
Short-term biological variation of serum glial fibrillary acidic protein
Christensen, S. H., Hviid, C. V. B., Madsen, A. T., Parkner, T., & Winther‐Larsen, A. (2022) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2022-0480 · Cited by 14
Therapeutic Properties of Ayahuasca Components in Ischemia/Reperfusion Injury of the Eye
Szilágyi, A., Takács, B., Szekeres, R., Tarjányi, V., Bombicz, M., Priksz, D., Kovacs, A. I., Juhász, B., Frecska, E., Szilvássy, Z., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10050997 · Cited by 13
Utilization of ethanolamine phosphate phospholyase as a unique astrocytic marker
Tsujioka, H., & Yamashita, T. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1097512 · Cited by 11
Dalenogare, D. P., de Araújo, D. S. M., Landini, L., Titiz, M., Siena, G. D., Logu, F. D., Geppetti, P., Nassini, R., & Trevisan, G. (2023) · Cells · doi:10.3390/cells12111511 · Cited by 13
Verma, H., Kaur, S., Kaur, S., Gangwar, P., Dhiman, M., & Mantha, A. K. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04053-3 · Cited by 11
Rathee, S., Sen, D., Pandey, V., & Jain, S. (2024) · Current Drug Targets · doi:10.2174/0113894501320096240627071400 · Cited by 16
Roll, L., Lessmann, K., Brüstle, O., & Faissner, A. (2022) · Cells · doi:10.3390/cells11050760 · Cited by 13
Cortical Pathology in Vanishing White Matter
Man, J. H. K., van Gelder, C. A. G. H., Breur, M., Okkes, D., Molenaar, D., van der Sluis, S., Abbink, T. E. M., Altelaar, M. A. F., van der Knaap, M. S., & Bugiani, M. (2022) · Cells · doi:10.3390/cells11223581 · Cited by 11
Specific Methyl-CpG Configurations Define Cell Identity through Gene Expression Regulation
Improda, T., Morgera, V., Vitale, M., Chiariotti, L., Passaro, F., Feola, A., Porcellini, A., Cuomo, M., & Pezone, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24129951 · Cited by 11
Bayat, H., Mirahmadi, M., Azarshin, Z., Ohadi, H., Delbari, A., & Ohadi, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-52675-3 · Cited by 11
Hepatic ketogenesis is not required for starvation adaptation in mice
Feola, K. C., Venable, A. H., Broomfield, T., Villegas, M., Fu, X., Burgess, S. C., & Huen, S. C. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.101967 · Cited by 11
Nölle, A., van Dijken, I., Waelti, C. M., Calini, D., Bryois, J., Lezan, E., Golling, S., Augustin, A., Foo, L. C., & Hoozemans, J. J. M. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.772011 · Cited by 10
Neural lineage differentiation of human pluripotent stem cells: Advances in disease modeling
Yan, Y.-W., Qian, E. S., Woodard, L. E., & Bejoy, J. (2023) · World Journal of Stem Cells · doi:10.4252/wjsc.v15.i6.530 · Cited by 11
Comparison of two protocols for the generation of iPSC-derived human astrocytes
Mulica, P., Venegas, C., Landoulsi, Z., Badanjak, K., Delcambre, S., Tziortziou, M., Hezzaz, S., Ghelfi, J., Smajić, S., Schwamborn, J. C., et al. (2023) · Biological Procedures Online · doi:10.1186/s12575-023-00218-x · Cited by 10
Shen, K., Shi, Y., Wang, X., & Leung, S. W. S. (2024) · Aging and Disease · doi:10.14336/ad.202.0424 · Cited by 12
Role of tunneling nanotubes in neuroglia
Xu, W., Yang, X., Zheng, H., Chen, C., & Yuan, J. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-01129 · Cited by 11
A human neuron Alzheimer’s disease model reveals barriers to senolytic translatability
Walton, C. C., Wang, E. Y., Lee, S., Siebrand, C. J., Bergo, N. J., Mayeri, Z., & Andersen, J. K. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01822-7 · Cited by 10
STORIES: learning cell fate landscapes from spatial transcriptomics using optimal transport
Huizing, G.-J., Samaran, J., Capocefalo, D., Audit, A., Gabriel Peyré, A., & Cantini, L. (2025) · Nature Methods · doi:10.1038/s41592-025-02855-4 · Cited by 19
Clickable Biomaterials for Modulating Neuroinflammation
Cornelison, R. C., & Fadel, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158496 · Cited by 10
Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain
Hasegawa, H., & Kondo, M. (2023) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b23-00140 · Cited by 9
Tuning a Bioengineered Hydrogel for Studying Astrocyte Reactivity in Glioblastoma
DePalma, T. J., Hisey, C. L., Hughes, K., Fraas, D., Tawfik, M., Scharenberg, J., Wiggins, S., Nguyen, K. T., Hansford, D. J., Reátegui, E., et al. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.09.048 · Cited by 10
Identifying similar populations across independent single cell studies without data integration
González-Velasco, Ó., Simon, M., Yilmaz, R., Parlato, R., Weishaupt, J. H., Imbusch, C. D., & Brors, B. (2025) · NAR Genomics and Bioinformatics · doi:10.1093/nargab/lqaf042 · Cited by 10
Baraka, S. M., Hussien, Y. A., Ahmed-Farid, O. A.-H., Hassan, A. M., & Saleh, D. O. (2026) · Scientific Reports · doi:10.1038/s41598-025-34650-8 · Cited by 9
Liu, Y., Peng, J., Leng, Q., Tian, Y., Wu, X., & Tan, R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065206 · Cited by 9
Mukherjee, S., Tarale, P., & Sarkar, D. K. (2023) · Cells · doi:10.3390/cells12182323 · Cited by 9
Metabolic disorders exacerbate the formation of glial scar after stroke
Clain, J., Couret, D., Bringart, M., Lecadieu, A., Meilhac, O., d’Hellencourt, C. L., & Diotel, N. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16325 · Cited by 9
Effects of voluntary and forced physical exercise on the retinal health of aging Wistar rats
Szilágyi, A., Takács, B., Szekeres, R., Tarjányi, V., Nagy, D., Priksz, D., Bombicz, M., Kiss, R., Szabó, A. M., Lehoczki, A., et al. (2024) · GeroScience · doi:10.1007/s11357-024-01208-x · Cited by 10
Auricchio, A., Baroni, S., Jahromi, B. R., Gris, A. V., Sturiale, C. L., Ceccarelli, G. M., Obersnel, M., Menna, G., Martinelli, R., Napoli, G., et al. (2024) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2024.06.003 · Cited by 9
Mast, N., Li, Y., & Pikuleva, I. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147669 · Cited by 10
Regulation of sleep quantity and intensity by long and short isoforms of SLEEPY kinase
Xu, J., Zhou, R., Wang, G., Guo, Y., Gao, X., Zhou, S., Ma, C., Chen, L., Shi, B., Wang, H., et al. (2022) · SLEEP · doi:10.1093/sleep/zsac198 · Cited by 12
Castillo-González, J., Buscemi, L., Vargas-Rodríguez, P., Serrano-Martínez, I., Forte‐Lago, I., Caro, M., Price, M., Hernández‐Cortés, P., Hirt, L., & González‐Rey, E. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107501 · Cited by 8
Lao, D., Gong, Z., Li, T., Mo, X., & Huang, W. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04270-1 · Cited by 8
Humpel, C. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1540150 · Cited by 8
van Hijfte, L., Geurts, M., de Heer, I. J., Ghisai, S. A., Balcioglu, H. E., Hoogstrate, Y., Vallentgoed, W., Head, R., Luning, R., van den Bosch, T. P. P., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56441-5 · Cited by 8
Sun, L. V., Xu, M., Zhou, C., Cao, S.-D., Zhang, X., Guan, S.-Q., Sang, W.-X., & Li, X. (2025) · World Journal of Psychiatry · doi:10.5498/wjp.v15.i6.103661 · Cited by 8
Do astrocytes act as immune cells after pediatric TBI?
Panchenko, P. E., Hippauf, L., Konsman, J. P., & Badaut, J. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106231 · Cited by 9
Dowling, P., Trollet, C., Négroni, E., Swandulla, D., & Ohlendieck, K. (2024) · Proteomes · doi:10.3390/proteomes12010004 · Cited by 10
Terzo, S., Amato, A., Calvi, P., Giardina, M., Nuzzo, D., Picone, P., Piccionello, A. P., Amata, S., Giardina, I. C., Massaro, A. S., et al. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-02039 · Cited by 8
Wang, J., Du, K., Liu, C., Chen, X., Ban, W., Zhu, G., & Yang, J. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1428907 · Cited by 8
Metadata
- Authors
- Jurga, A. M., Paleczna, M., Kadluczka, J., & Kuter, K. Z.
- Affiliations
- Maj Institute of Pharmacology (PL)
- Department of Neuropsychopharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Kraków, Poland
- Corresponding author
- Kuter, Katarzyna Z.
- Venue
- Biomolecules
- Publisher
- MDPI AG
- Published
- 2021-09-14
- Volume
- 11
- Issue
- 9
- Pages
- 1361
- ISSN
- 2218-273X (ISSN-L)
- PMC
- PMC8468264
- OpenAlex
- W3201129361
- Cited by
- 319
- References
- 215
- Citations by year
- 2026: 58 · 2025: 85 · 2024: 85 · 2023: 50 · 2022: 37 · 2021: 3
- FWCI
- 5.17
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Biomolecules (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk (OPUS14 2017/27/B/NZ7/00289)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- astrocytes, astrocyte markers, glial fibrillary acidic protein, glial heterogeneity, glial phenotype, astrocyte-neuron interaction, glial cells, aging, neurodegenerative diseases, diagnostic biomarkers, central nervous system
- MeSH terms
- Aging, Animals, Astrocytes, Brain, Cell Communication, Glial Fibrillary Acidic Protein, Humans, Biomarkers
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
