Beyond the GFAP-Astrocyte Protein Markers in the Brain

Glutamate neurotoxicity and diseases of the nervous system

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Neurotoxic reactive astrocytes are induced by activated microglia

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Astrocyte-endothelial interactions at the blood-brain barrier

Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875 · cited 1×

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Zeisel, A., Muñoz-Manchado, A. B., Codeluppi, S., Lönnerberg, P., La Manno, G., Juréus, A., Marques, S., Munguba, H., He, L., Betsholtz, C., et al. (2015) · Science · doi:10.1126/science.aaa1934 · Cited by 3,124

Cellular Scaling Rules for the Brains of Marsupials: Not as “Primitive” as Expected

Santos, S. E. D., Porfírio, J., Cunha, F., Manger, P. R., Tavares, W. C., Pessôa, L. M., Raghanti, M. A., Sherwood, C. C., & Herculano‐Houzel, S. (2017) · Brain Behavior and Evolution · doi:10.1159/000452856 · Cited by 2,652

Single-cell transcriptomic analysis of Alzheimer’s disease

Mathys, H., Davila-Velderrain, J., Peng, Z., Gao, F., Mohammadi, S., Young, J. Z., Menon, M., He, L., Abdurrob, F., Jiang, X., et al. (2019) · Nature · doi:10.1038/s41586-019-1195-2 · Cited by 2,568

Reactive astrocyte nomenclature, definitions, and future directions

Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-020-00783-4 · Cited by 2,513 · cited 3×

Genomic analysis of reactive astrogliosis

Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., & Barres, B. A. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6221-11.2012 · Cited by 2,404

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

Azevedo, F. A. C., Carvalho, L. R. B., Grinberg, L. T., Farfel, J. M., Ferretti, R. E. L., Leite, R. E. P., Filho, W. J., Lent, R., & Herculano‐Houzel, S. (2009) · Journal of Comparative Neurology · doi:10.1002/cne.21974 · Cited by 2,337

Reactive Astrocytes: Production, Function, and Therapeutic Potential

Liddelow, S. A., & Barres, B. A. (2017) · Immunity · doi:10.1016/j.immuni.2017.06.006 · Cited by 2,336

The glymphatic system: a beginner's guide

Jessen, N. A., Munk, A. S. F., Lundgaard, I., & Nedergaard, M. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1581-6 · Cited by 2,075

Localization of neuronal and glial glutamate transporters

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Physiology of Astroglia

Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678

Uniquely Hominid Features of Adult Human Astrocytes

Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4707-08.2009 · Cited by 1,488

Diversity of astrocyte functions and phenotypes in neural circuits

Khakh, B. S., & Sofroniew, M. V. (2015) · Nature Neuroscience · doi:10.1038/nn.4043 · Cited by 1,239

Normal aging induces A1-like astrocyte reactivity

Clarke, L. E., Liddelow, S. A., Chakraborty, C., Münch, A. E., Heiman, M., & Barres, B. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800165115 · Cited by 1,237

GFAP in health and disease

Middeldorp, J., & Hol, E. M. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.01.005 · Cited by 1,080

Overview of General and Discriminating Markers of Differential Microglia Phenotypes

Jurga, A. M., Paleczna, M., & Kuter, K. Z. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00198 · Cited by 1,000

Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system

Hol, E. M., & Pekny, M. (2015) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2015.02.004 · Cited by 917

Overview of complement activation and regulation

Noris, M., & Remuzzi, G. (2013) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2013.08.001 · Cited by 864

Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

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Cell type- and brain region-resolved mouse brain proteome

Sharma, K., Schmitt, S., Bergner, C. G., Tyanova, S., Kannaiyan, N., Manrique-Hoyos, N., Kongi, K., Cantuti, L., Hanisch, U.-K., Philips, M.-A., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4160 · Cited by 785 · cited 4×

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

Chai, H., Diaz-Castro, B., Shigetomi, E., Monte, E., Octeau, J. C., Yu, X., Cohn, W., Rajendran, P. S., Vondriska, T. M., Whitelegge, J. P., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.029 · Cited by 769

Aquaporin‐4 facilitates reabsorption of excess fluid in vasogenic brain edema

Papadopoulos, M. C., Manley, G. T., Krishna, S., & Verkman, A. S. (2004) · The FASEB Journal · doi:10.1096/fj.04-1723fje · Cited by 749

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Mathys, H., Adaikkan, C., Gao, F., Young, J. Z., Manet, E., Hemberg, M., De Jager, P. L., Ransohoff, R. M., Regev, A., & Tsai, L.-H. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.09.039 · Cited by 740

Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity

Sofroniew, M. V. (2020) · Trends in Immunology · doi:10.1016/j.it.2020.07.004 · Cited by 721

The aging astrocyte transcriptome from multiple regions of the mouse brain.

Boisvert, M. M., Erikson, G. A., Shokhirev, M. N., & Allen, N. J. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.039 · Cited by 702

The Number of Glutamate Transporter Subtype Molecules at Glutamatergic Synapses: Chemical and Stereological Quantification in Young Adult Rat Brain

Lehre, K. P., & Danbolt, N. C. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-21-08751.1998 · Cited by 691

The Role of Astrocytes in CNS Inflammation

Giovannoni, F., & Quintana, F. J. (2020) · Trends in Immunology · doi:10.1016/j.it.2020.07.007 · Cited by 681

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

Vainchtein, I. D., Chin, G., Cho, F. S., Kelley, K. W., Miller, J. G., Chien, E. C., Liddelow, S. A., Nguyen, P. T., Nakao-Inoue, H., Dorman, L. C., et al. (2018) · Science · doi:10.1126/science.aal3589 · Cited by 657

Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury

Wilhelmsson, U., Bushong, E. A., Price, D. L., Smarr, B. L., Phung, V., Terada, M., Ellisman, M. H., & Pekny, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602841103 · Cited by 643 · cited 2×

Heterogeneity of astrocytic form and function.

Oberheim, N. A., Goldman, S. A., & Nedergaard, M. (2012) · Methods in Molecular Biology · doi:10.1007/978-1-61779-452-0_3 · Cited by 638

Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation

Parri, H. R., Gould, T. M., & Crunelli, V. (2001) · Nature Neuroscience · doi:10.1038/90507 · Cited by 635

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

Nair‐Roberts, R. G., Chatelain-Badie, S. D., Benson, E. M., White‐Cooper, H., Bolam, J. P., & Ungless, M. A. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.046 · Cited by 635

Functional diversity of astrocytes in neural circuit regulation

Haim, L. B., & Rowitch, D. H. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.159 · Cited by 618

S100B in brain damage and neurodegeneration

Rothermundt, M., Peters, M., Prehn, J. H. M., & Arolt, V. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10303 · Cited by 610

Neocortical glial cell numbers in human brains

Pelvig, D. P., Pakkenberg, H., Stark, A. K., & Pakkenberg, B. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.04.013 · Cited by 601

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

Tong, X., Ao, Y., Faas, G. C., Nwaobi, S. E., Xu, J., Haustein, M. D., Anderson, M. A., Mody, I., Olsen, M. L., Sofroniew, M. V., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3691 · Cited by 592

The “quad‐partite” synapse: Microglia‐synapse interactions in the developing and mature CNS

Schafer, D. P., Lehrman, E. K., & Stevens, B. (2013) · Glia · doi:10.1002/glia.22389 · Cited by 570

GFAP Is Necessary for the Integrity of CNS White Matter Architecture and Long-Term Maintenance of Myelination

Liedtke, W., Edelmann, W., Bieri, P. L., Chiu, F.-C., Cowan, N. J., Kucherlapati, R., & Raine, C. S. (1996) · Neuron · doi:10.1016/s0896-6273(00)80194-4 · Cited by 538

Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease

Chinta, S. J., Woods, G., Demaria, M., Rane, A., Zou, Y., McQuade, A., Rajagopalan, S., Limbad, C., Madden, D. T., Campisi, J., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.092 · Cited by 530

Identification of diverse astrocyte populations and their malignant analogs

John Lin, C.-C., Yu, K., Hatcher, A., Huang, T.-W., Lee, H. K., Carlson, J., Weston, M. C., Chen, F., Zhang, Y., Zhu, W., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4493 · Cited by 525

Maturation of astrocyte morphology and the establishment of astrocyte domains during postnatal hippocampal development

Bushong, E. A., Martone, M. E., & Ellisman, M. H. (2004) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2003.12.008 · Cited by 463

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

Priego, N., Zhu, L., Monteiro, C., Mulders, M., Wasilewski, D., Bindeman, W., Doglio, L., Martínez, L., Martínez-Saez, E., Ramón y Cajal, S., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0044-4 · Cited by 452

Astrocytes in physiological aging and Alzheimer’s disease

Rodríguez-Arellano, J. J., Parpura, V., Zorec, R., & Verkhratsky, A. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.01.007 · Cited by 439

Glia: Initiators and progressors of pathology in Parkinson's disease

Halliday, G. M., & Stevens, C. H. (2011) · Movement Disorders · doi:10.1002/mds.23455 · Cited by 436

Segregated Expression of AMPA-Type Glutamate Receptors and Glutamate Transporters Defines Distinct Astrocyte Populations in the Mouse Hippocampus

Matthias, K., Kirchhoff, F., Seifert, G., Hüttmann, K., Matyash, M., Kettenmann, H., & Steinhäuser, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01750.2003 · Cited by 436

Energy Contribution of Octanoate to Intact Rat Brain Metabolism Measured by 13 C Nuclear Magnetic Resonance Spectroscopy

Ebert, D., Haller, R. G., & Walton, M. E. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-13-05928.2003 · Cited by 427

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

Soreq, L., Rose, J., Soreq, E., Hardy, J., Trabzuni, D., Cookson, M. R., Smith, C., Ryten, M., Patani, R., & Ule, J. (2017) · Cell Reports · doi:10.1016/j.celrep.2016.12.011 · Cited by 419

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

Choi, S. S., Lee, H. J., Lim, I., Satoh, J., & Kim, S. U. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092325 · Cited by 411

Thrombospondins: Multifunctional Regulators of Cell Interactions

Adams, J. C. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.25 · Cited by 407

Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct

Miller, R., & RAFF, M. C. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-02-00585.1984 · Cited by 396

Induction of Glial Fibrillary Acidic Protein Expression in Astrocytes by Nitric Oxide

Brahmachari, S., Fung, Y. K., & Pahan, K. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.5480-05.2006 · Cited by 390

The glutamate‐glutamine cycle is not stoichiometric: Fates of glutamate in brain

McKenna, M. C. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21444 · Cited by 385

Astroglial networks scale synaptic activity and plasticity

Pannasch, U., Vargová, L., Reingruber, J., Ezan, P., Holcman, D., Giaume, C., Syková, E., & Rouach, N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016650108 · Cited by 383

Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-β after Vascular Damage

Schachtrup, K., Ryu, J. K., Helmrick, M. J., Vagena, E., Galanakis, D. K., Degen, J. L., Margolis, R. U., & Akassoglou, K. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0137-10.2010 · Cited by 379

SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

Sun, W., Cornwell, A., Li, J., Peng, S., Osorio, M. J., Aalling, N., Wang, S., Benraiss, A., Lou, N., Goldman, S. A., et al. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3199-16.2017 · Cited by 357

Spatial and temporal relationship between monocyte chemoattractant protein‐1 expression and spinal glial activation following peripheral nerve injury

Zhang, J., & Koninck, Y. D. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03746.x · Cited by 345

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

Faideau, M., Kim, J., Cormier, K., Gilmore, R., Welch, M. J., Aurégan, G., Dufour, N., Guillermier, M., Brouillet, E., Hantraye, P., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq212 · Cited by 343

Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code

Hochstim, C., Deneen, B., Lukaszewicz, A., Zhou, Q., & Anderson, D. J. (2008) · Cell · doi:10.1016/j.cell.2008.02.046 · Cited by 331

The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease

Mirza, B., Hadberg, H., Thomsen, P., & Moos, T. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00455-8 · Cited by 327

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

Lanjakornsiripan, D., Pior, B., Kawaguchi, D., Furutachi, S., Tahara, T., Katsuyama, Y., Suzuki, Y., Fukazawa, Y., & Gotoh, Y. (2018) · Nature Communications · doi:10.1038/s41467-018-03940-3 · Cited by 324

Variations in Promoter Activity Reveal a Differential Expression and Physiology of Glutamate Transporters by Glia in the Developing and Mature CNS

Regan, M. R., Huang, Y. H., Kim, Y., Dykes‐Hoberg, M., Jin, L., Watkins, A. M., Bergles, D. E., & Rothstein, J. D. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0790-07.2007 · Cited by 314

Cytokines: Powerful Regulators of Glial Cell Activation

John, G. R., Lee, S. C., & Brosnan, C. F. (2003) · The Neuroscientist · doi:10.1177/1073858402239587 · Cited by 312

Astroglial heterogeneity closely reflects the neuronal-defined anatomy of the adult murine CNS

Emsley, J. G., & Macklis, J. D. (2006) · Neuron Glia Biology · doi:10.1017/s1740925x06000202 · Cited by 304

Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

Itoh, Y., Esaki, T., Shimoji, K., Cook, M., Law, M. J., Kaufman, E., & Sokoloff, L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0831078100 · Cited by 297

GAT-3, a High-Affinity GABA Plasma Membrane Transporter, Is Localized to Astrocytic Processes, and It Is Not Confined to the Vicinity of GABAergic Synapses in the Cerebral Cortex

Minelli, A., Debiasi, S., Brecha, N. C., Vitellaro‐Zuccarello, L., & Conti, F. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-19-06255.1996 · Cited by 295

Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism

Chao, C. C., Hu, S., Sheng, W. S., Bu, D.-F., Bukrinsky, M., & Peterson, P. K. (1996) · Glia · doi:10.1002/(sici)1098-1136(199603)16:3 · Cited by 273

Spatial and temporal activation of spinal glial cells: Role of gliopathy in central neuropathic pain following spinal cord injury in rats

Gwak, Y. S., Kang, J., Unabia, G. C., & Hulsebosch, C. E. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.10.010 · Cited by 270

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

Farmer, W. T., Abrahamsson, T., Chierzi, S., Lui, C. G., Zaelzer, C. A., Jones, E. V., Bally, B. P., Chen, G. G., Théroux, J., Peng, J., et al. (2016) · Science · doi:10.1126/science.aab3103 · Cited by 270

Gliotransmitter Release from Astrocytes: Functional, Developmental, and Pathological Implications in the Brain

Harada, K., Kamiya, T., & Tsuboi, T. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00499 · Cited by 267

Molecular signals of plasticity at the tetrapartite synapse

Dityatev, A., & Rusakov, D. A. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.12.006 · Cited by 267

Molecular comparison of GLT1 + and ALDH1L1 + astrocytes in vivo in astroglial reporter mice

Yang, Y., Vidensky, S., Jin, L., Jie, C., Lorenzini, I., Frankl, M., & Rothstein, J. D. (2010) · Glia · doi:10.1002/glia.21089 · Cited by 264

Single-nucleus RNA-seq identifies Huntington disease astrocyte states

Al-Dalahmah, O., Sosunov, A. A., Shaik, A., Ofori, K., Liu, Y., Vonsattel, J. P., Adorjan, I., Menon, V., & Goldman, J. E. (2020) · Acta Neuropathologica Communications · doi:10.1186/s40478-020-0880-6 · Cited by 264

Bioenergetics and redox adaptations of astrocytes to neuronal activity

Bolaños, J. P. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13486 · Cited by 262

Exocytotic Release of ATP from Cultured Astrocytes

Pangršič, T., Potokar, M., Stenovec, M., Kreft, M., Fabbretti, E., Nistri, A., Pryazhnikov, E., Khiroug, L. S., Giniatullin, R. A., & Zorec, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700290200 · Cited by 245

Molecular and Functional Properties of Regional Astrocytes in the Adult Brain

Morel, L., Chiang, M. S. R., Higashimori, H., Shoneye, T., Iyer, L. K., Yelick, J., Tai, A., & Yang, Y. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3956-16.2017 · Cited by 243

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome‐wide expression analysis

Götz, M., Sirko, S., Beckers, J., & Irmler, M. (2015) · Glia · doi:10.1002/glia.22850 · Cited by 237

Analysis of Astroglial K+ Channel Expression in the Developing Hippocampus Reveals a Predominant Role of the Kir4.1 Subunit

Seifert, G., Hüttmann, K., Binder, D. K., Hartmann, C. J., Wyczynski, A., Neusch, C., & Steinhäuser, C. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3790-08.2009 · Cited by 236

Interleukin-10, interleukin-4, and transforming growth factor-? differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells

Ledeboer, A., Brev�, J. J. P., Poole, S., Tilders, F. J. H., & van Dam, A. (2000) · Glia · doi:10.1002/(sici)1098-1136(200004)30:2 · Cited by 233

Phenotypic Polarization of Activated Astrocytes: The Critical Role of Lipocalin-2 in the Classical Inflammatory Activation of Astrocytes

Jang, E., Kim, J., Lee, S., Kim, J., Seo, J.-W., Jin, M., Lee, M., Jang, I., Lee, W., & Suk, K. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301637 · Cited by 230

Immune reactive cells in senile plaques and cognitive decline in Alzheimer’s disease

Vehmas, A. K., Kawas, C. H., Stewart, W. F., & Troncoso, J. C. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00090-8 · Cited by 230

Astrocytic GABA transporter activity modulates excitatory neurotransmission

Boddum, K., Jensen, T. P., Magloire, V., Kristiansen, U., Rusakov, D. A., Pavlov, I., & Walker, M. C. (2016) · Nature Communications · doi:10.1038/ncomms13572 · Cited by 222

Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain

Rafiki, A., Boulland, J., Halestrap, A. P., Ottersen, O. P., & Bergersen, L. H. (2003) · Neuroscience · doi:10.1016/j.neuroscience.2003.08.040 · Cited by 221

The effects of microglia‐ and astrocyte‐derived factors on neurogenesis in health and disease

Araki, T., Ikegaya, Y., & Koyama, R. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14969 · Cited by 220

MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation

Fricker, M., Neher, J. J., Zhao, J.-W., Théry, C., Tolkovsky, A. M., & Brown, G. C. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.4837-11.2012 · Cited by 218

3-Phosphoglycerate Dehydrogenase, a Key Enzyme forl-Serine Biosynthesis, Is Preferentially Expressed in the Radial Glia/Astrocyte Lineage and Olfactory Ensheathing Glia in the Mouse Brain

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Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

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Molecular imaging of nestin in neuroinflammatory conditions reveals marked signal induction in activated microglia

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Expression and localization of the iron–siderophore binding protein lipocalin 2 in the normal rat brain and after kainate-induced excitotoxicity

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The Role of Tenascin-C in Tissue Injury and Repair After Stroke

Okada, T., & Suzuki, H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.607587 · Cited by 57

Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes

Campbell, S. C., Muñoz‐Ballester, C., Chaunsali, L., Mills, W. A., Yang, J. H., Sontheimer, H. W., & Robel, S. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.104628 · Cited by 50

Astrocytic Cx43 and Cx30 differentially modulate adult neurogenesis in mice

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S100B Transgenic Mice Develop Features of Parkinson's Disease

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Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development

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In Vitro and In Vivo Activation of Astrocytes by Amyloid-β is Potentiated by Pro-Oxidant Agents

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Role of Astroglial Hemichannels and Pannexons in Memory and Neurodegenerative Diseases

Orellana, J. A., Retamal, M. A., Moraga‐Amaro, R., & Stehberg, J. (2016) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2016.00026 · Cited by 44

Brain Region-Specific Gene Signatures Revealed by Distinct Astrocyte Subpopulations Unveil Links to Glioma and Neurodegenerative Diseases

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Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory

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Adult Spinal Cord Radial Glia Display a Unique Progenitor Phenotype

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Matrix Metalloproteinases, Neural Extracellular Matrix, and Central Nervous System Pathology

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Disrupted function of lactate transporter MCT1 , but not MCT4 , in Schwann cells affects the maintenance of motor end‐plate innervation

Bouçanova, F., Pollmeier, G., Sándor, K., Morado-Urbina, C. E., Nijssen, J., Médard, J., Bartesaghi, L., Pellerin, L., Svensson, C. I., Hedlund, E., et al. (2020) · Glia · doi:10.1002/glia.23889 · Cited by 38

Developmental expression of Kir4.1 in astrocytes and oligodendrocytes of rat somatosensory cortex and hippocampus

Moroni, R. F., Inverardi, F., Regondi, M. C., Pennacchio, P., & Frassoni, C. (2015) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2015.09.004 · Cited by 37

GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson’s Disease and Lewy Body Dementia

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Astroglial Integrins in the Development and Regulation of Neurovascular Units

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Cell-Penetrating Mx1 Enhances Anti-Viral Resistance against Mucosal Influenza Viral Infection

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Mechanical elongation of astrocyte processes to create living scaffolds for nervous system regeneration

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EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes

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Temporal relationship between aquaporin-4 and glial fibrillary acidic protein in cerebellum of neonate and adult rats administered a BBB disrupting spider venom

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Glutamine Supplementation Ameliorates Chronic Stress-induced Reductions in Glutamate and Glutamine Transporters in the Mouse Prefrontal Cortex

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GFAP as a Potential Biomarker for Alzheimer’s Disease: A Systematic Review and Meta-Analysis

Kim, K. Y., Shin, K. Y., & Chang, K.-A. (2023) · Cells · doi:10.3390/cells12091309 · Cited by 309

Calcium signaling in astrocytes and gliotransmitter release

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Astrocytes in Chronic Pain: Cellular and Molecular Mechanisms

Lu, H.-J., & Gao, Y.-J. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-022-00961-3 · Cited by 118

Smouldering‐Associated Worsening in Multiple Sclerosis: An International Consensus Statement on Definition, Biology, Clinical Implications, and Future Directions

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Astrocyte-Mediated Neuroinflammation in Neurological Conditions

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Astrocyte Activation Markers

Gorina, Y. V., Salmina, A. B., Erofeev, A. I., Gerasimov, E., Bolshakova, A. V., Balaban, P. M., Борисович, Б. И., & Власова, О. Л. (2022) · Biochemistry (Moscow) · doi:10.1134/s0006297922090012 · Cited by 21

Astrocyte phenotypes: Emphasis on potential markers in neuroinflammation.

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ASTROCYTE MARKER ENZYMES

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Markers of Central Nervous System Glia and Neurons In Vivo During Normal and Pathological Conditions

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Neurodegenerative Diseases: Unraveling the Heterogeneity of Astrocytes

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