Cited by 30Coconut Research and ApplicationsFood and Agricultural SciencesPhytochemicals and Antioxidant Activities

Nutritional Profiles, Phytochemical Analysis, Antioxidant Activity and DNA Damage Protection of Makapuno Derived from Thai Aromatic Coconut

Open access
Phonphoem, Wannarat, Sinthuvanich, Chomdao, Aramrak, Attawan, Sirichiewsakul, Suteekarn, Arikit, Siwaret, Yokthongwattana, Chotika·2022·Foods

Abstract

Makapuno is a natural mutant coconut cultivar with jelly-like endosperm. Here, we investigated the nutritional compositions, active ingredients, and antioxidant activities of Makapuno meat and water. The contents of macronutrients, sugars, vitamins, amino acids, and fatty acids were reported. We found that Makapuno meat has higher dietary fiber with lower protein and fat content compared to normal coconut meat. Medium-chain fatty acids were the major fat component of Makapuno meat and water. Phytochemical analysis revealed that while flavonoid content was lower, the total phenolic, alkaloid, and tannin contents of Makapuno meat were comparable with those of mature coconut. However, Makapuno water contained higher alkaloid content when compared to mature and young coconuts. The antioxidant activities, as examined by DPPH, FRAP, and ABTS assays, showed that Makapuno meat and water had antioxidant activities, and Makapuno water exhibited protective activity against DNA damage. Hence, this research provides the nutraceutical importance of Makapuno, which could be used in the food industry.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3390/foods11233912

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 47

  1. [1]Moumita C. Adinpunya M. The antioxidant and antimicrobial properties of the methanolic extract from Cocos nucifera mesocarp Food Chem. 2008 107 994 999 10.1016/j.foodchem.2007.08.083 · DOI
  2. [3]Tuyekar S.T. Tawade B.S. Singh K.S. Wagh V.S. Vidhate P.K. Yevale R.P. Gaikwad S. Kale M. An Overview on Coconut Water: As A Multipurpose Nutrition Int. J. Pharm. Sci. Rev. Res. 2021 68 63 70 10.47583/ijpsrr.2021.v68i02.010 · DOI · Paper page
  3. [4]Bhagya D. Prema L. Rajamohan T. Therapeutic effects of tender coconut water on oxidative stress in fructose fed insulin resistant hypertensive rats Asian Pac. J. Trop. Med. 2012 5 270 276 10.1016/S1995-7645(12)60038-8 22449517 · DOI · Paper page
  4. [5]Gandhi M. Aggarwal M. Puri S. Singla S.K. Prophylactic effect of coconut water (Cocos nucifera L.) on ethylene glycol induced nephrocalcinosis in male wistar rat Int. Braz. J. Urol. 2013 39 108 117 10.1590/S1677-5538.IBJU.2013.01.14 23489503 · DOI · Paper page
  5. [6]Loki A. Rajamohan T. Hepatoprotective and antioxidant effect of tender coconut water on carbon tetrachloride induced liver injury in rats Indian J. Biochem. Biophys. 2003 40 354 357 22900330
  6. [7]Rao S. Najam R. Coconut water of different maturity stages ameliorates inflammatory processes in model of inflammation J. Intercul. Ethnopharmacol. 2016 5 244 249 10.5455/jice.20160402120142 PMC4927129 27366350 · DOI · Paper page
  7. [8]Salil G. Nevin K.G. Rajamohan T. Coconut kernel-derived proteins enhance hypolipidemic and antioxidant activity in alloxan-induced diabetic rats Int. J. Food Sci. Nutr. 2012 64 327 332 10.3109/09637486.2012.738646 23113582 · DOI
  8. [9]Nguyen Q.T. Bandupriya H.D.D. Foale M. Adkins S.W. Biology, propagation and utilization of elite coconut varieties (makapuno and aromatics) Plant Physiol. Biochem. 2016 109 579 589 10.1016/j.plaphy.2016.11.003 27838599 · DOI
  9. [10]Luengwilai K. Beckles D.M. Pluemjit O. Siriphanich J. Postharvest quality and storage life of ‘Makapuno’ coconut (Co-cos nucifera L.) Sci. Hortic. 2014 175 105e110 10.1016/j.scienta.2014.06.005 · DOI
  10. [11]Sukendah H. Volkaert H. Sudarsono S. Isolation and analysis of DNA fragment of genes related to Kopyor trait in coconut plant Indones J. Biotechnol. 2009 14 1169 1178 10.22146/ijbiotech.7814 · DOI
  11. [13]Tansakul A. Chaisawang P. Thermophysical properties of coconut milk J. Food Eng. 2006 73 276 280 10.1016/j.jfoodeng.2005.01.035 · DOI
  12. [15]Leorna M. Israel K.A. The influence of maturity of VMAC5 (Cocos nucifera L. ‘makapuno’) on its physicochemical, proxi-mate composition and fatty acid profile IOP Conf. Ser. Earth Environ. Sci. 2018 102 012098 10.1088/1755-1315/102/1/012098 · DOI
  13. [16]Chen Z. Chen B. Yao S. High-performance liquid chromatography/electrospray ionization-mass spectrometry for simultaneous determination of taurine and 10 water-soluble vitamins in multivitamin tablets Anal. Chim. Acta 2006 569 169 175 10.1016/j.aca.2006.03.099 · DOI
  14. [17]DeVries J.W. Egberg D.C. Heroff J.C. Concurrent analysis of vitamin A and vitamin E by reversed phase high performance liquid chromatography Liquid Chromatographic Analysis of Food and Beverages Academic Press Cambridge, MA, USA 1979 477 497 10.1016/B978-0-12-169002-1.50016-2 · DOI
  15. [19]Çevikkalp S.A. Löker G.B. Yaman M. Amoutzopoulos B. A simplified HPLC method for determination of tryptophan in some cereals and legumes Food Chem. 2016 193 26 29 10.1016/j.foodchem.2015.02.108 26433283 · DOI
  16. [20]Attard E. A Rapid microtitre plate Folin-Ciocalteu method for the assessment of polyphenols Open Life Sci. 2013 48 48 53 10.2478/s11535-012-0107-3 · DOI
  17. [21]Chandra S. Khan S. Avula B. Lata H. Yang M.H. ElSohly M.A. Khan I.A. Assessment of total phenolic and flavonoid content, antioxidant properties, and yield of aeroponically and conventionally grown leafy vegetables and fruit crops: A comparative study Evid.-Based Complement Altern. Med. 2014 2014 1 9 10.1155/2014/253875 PMC3980857 24782905 · DOI
  18. [22]Leite L. Dourado L. Laboratory activities, science education and problem-solveing skills Procedia Soc. Behav. Sci. 2013 106 1677 1686 10.1016/j.sbspro.2013.12.190 · DOI
  19. [23]Fazel S. Hamidreza M. Rouhollah G. Mohammadreza V. Spectrophotometric determination of total alkaloids in some Iranian medicinal plants J. Appl. Hortic. 2010 12 69 70 10.37855/jah.2010.v12i01.15 · DOI
  20. [24]Herald T. Gadgil P. Tilley M. High-throughput micro plate assays for screening flavonoid content and DPPH-scavenging activity in sorghum bran and flour J. Sci. Food Agric. 2012 92 2326 2331 10.1002/jsfa.5633 22419130 · DOI
  21. [25]Bolanos de la Torre A.A. Henderson T. Nigam P.S. Owusu-Apenten R.K. A universally calibrated microplate ferric reducing antioxidant power (FRAP) assay for foods and applications to Manuka honey Food Chem. 2015 174 119 123 10.1016/j.foodchem.2014.11.009 25529660 · DOI
  22. [26]Thaipong K. Boonprakob U. Crosby K. Cisneros-Zevallos L. Byrne D.H. Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts J. Food. Compos. Anal. 2010 19 669 675 10.1016/j.jfca.2006.01.003 · DOI
  23. [27]Aruoma O.I. Methodological considerations for characterizing potential antioxidant actions of bioactive components in plant foods Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis Elsevier Amsterdam, The Netherlands 2003 523 9 20 10.1016/S0027-510700317-2 12628499 · DOI
  24. [28]Santoso U. Kubo K. Ota T. Tadokoro T. Maekawa A. Nutrient composition of kopyor coconuts (Cocos nucifera L.) Food Chem. 1996 57 299 304 10.1016/0308-8146(95)00237-5 · DOI · Paper page
  25. [29]Ngampeerapong C. Chavasit V. Nutritional and bioactive compounds in coconut meat of different sources: Thailand, Indonesia and Vietnam CMU J. Nat Sci. 2019 18 562 573 10.12982/CMUJNS.2019.0037 · DOI · Paper page
  26. [31]Trinidad T.P. Valdez D.H. Loyola A.S. Mallillin A.C. Askali F.C. Castillo J.C. Masa D.B. Glycaemic index of different coconut (Cocos nucifera)-flour products in normal and diabetic subjects Br. J. Nutr. 2003 90 551 556 10.1079/BJN2003944 13129460 · DOI
  27. [32]Trinidad T.P. Mallillin A.C. Valdez D.H. Loyola A.S. Askali-Mercado F.C. Castillo J.C. Encabo R.R. Masa D.B. Maglaya A.S. Chua M.T. Dietary fiber from coconut flour: A functional food Innov. Food Sci. Emerg. Technol. 2006 7 309 317 10.1016/j.ifset.2004.04.003 · DOI
  28. [33]Abbasiliasi S. Tan S.J. Bello B. Ibrahim T.A.T. Tam J.T. Ariff A. Mustafa S. Prebiotic efficacy of coconut kernel cake’s soluble crude polysaccharides on growth rates and acidifying property of probiotic lactic acid bacteria in vitro Biotechnol. Biotechnol. Equip. 2019 33 1216 1227 10.1080/13102818.2019.1649603 · DOI
  29. [34]Hanafi F.N.A. Kamaruding N.A. Shaharuddin S. Influence of coconut residue dietary fiber on physicochemical, probiotic (Lactobacillus plantarum ATCC 8014) survivability and sensory attributes of probiotic ice cream Lebensm. -Wiss. Technol. 2022 154 112725 10.1016/j.lwt.2021.112725 · DOI
  30. [35]Huang L. Gao L. Chen C. Role of medium-chain fatty acids in healthy metabolism: A clinical perspective Trends Endocrinol. Metab. 2021 32 351 366 10.1016/j.tem.2021.03.002 33832826 · DOI
  31. [36]Labarthe F. Gélinas R. Des Rosiers C. Medium-chain fatty acids as metabolic therapy in cardiac disease Cardiovasc. Drugs Ther. 2008 22 97 106 10.1007/s10557-008-6084-0 18253821 · DOI
  32. [37]Zhou S. Wang Y. Jiang Y. Zhang Z. Sun X. Yu L.L. Dietary intake of structured lipids with different contents of medium-chain fatty acids on obesity prevention in C57BL/6J mice J. Food Sci. 2017 82 1968 1977 10.1111/1750-3841.13789 28631820 · DOI
  33. [38]DiNicolantonio J.J. O’Keefe J.H. Good fats versus bad fats: A comparison of fatty acids in the promotion of insulin resistance, inflammation, and obesity Mol. Med. 2017 114 303 307 PMC6140086 30228616
  34. [39]Budreviciute A. Damiati S. Sabir D.K. Onder K. Schuller-Goetzburg P. Plakys G. Katileviciute A. Khoja S. Kodzius R. Management and prevention strategies for non-communicable diseases (NCDs) and their risk factors Front. Public Health 2020 8 574111 10.3389/fpubh.2020.574111 33324597 PMC7726193 · DOI
  35. [41]Tan T.-C. Cheng L.-H. Bhat R. Rusul G. Easa A.M. Composition, physicochemical properties and thermal inactivation kinetics of polyphenol oxidase and peroxidase from coconut (Cocos nucifera) water obtained from immature, mature and overly-mature coconut Food Chem. 2014 142 121 128 10.1016/j.foodchem.2013.07.040 24001821 · DOI · Paper page
  36. [42]Mahmood T. Anwar F. Abbas M. Saari N. Effect of maturity on phenolics (phenolic acids and flavonoids) profile of strawberry cultivars and mulberry species from Pakistan Int. J. Mol. Sci. 2012 13 4591 4607 10.3390/ijms13044591 22605997 PMC3344233 · DOI
  37. [43]Grosso G. Dietary antioxidants and prevention of non-communicable diseases Antioxidants 2018 7 94 10.3390/antiox7070094 30029504 PMC6071097 · DOI
  38. [44]Setiawan B. Azra J.M. Nasution Z. Sulaeman A. Estuningsih S. Development of freeze-dried coconut drink and its nutrient content, sensory profile, and shelf life J. Culin Sci. Technol. 2022 10.1080/15428052.2022.2079578 · DOI
  39. [45]Shen N. Wang T. Gan Q. Liu S. Wang L. Jin B. Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity Food Chem. 2022 383 132531 10.1016/j.foodchem.2022.132531 35413752 · DOI
  40. [46]Pisoschi A.M. Pop A. Cimpeanu C. Predoi G. Antioxidant capacity determination in plants and plant-derived products: A review Oxid. Med. Cell Longev. 2016 2016 9130976 10.1155/2016/9130976 28044094 PMC5164913 · DOI
  41. [48]Karunasiri A.N. Gunawardane M. Senanayake C.M. Jayathilaka N. Seneviratne K.N. Antioxidant and nutritional properties of domestic and commercial coconut milk preparations Int. J. Food Sci. 2020 2020 3489605 10.1155/2020/3489605 32832538 PMC7422486 · DOI · Paper page
  42. [49]Li Y. Zheng Y. Zhang Y. Xu J. Gao G. Antioxidant activity of coconut (Cocos nucifera L.) protein fractions Molecules 2018 23 707 10.3390/molecules23030707 29558429 PMC6017440 · DOI
  43. [50]Olatunde O.O. Benjakul S. Vongkamjan K. Amnuaikit T. Liposomal encapsulated ethanolic coconut husk extract: Antioxidant and antibacterial properties J. Food Sci. 2019 84 3664 3673 10.1111/1750-3841.14853 31724746 · DOI
  44. [51]Asgha M.T. Yusof Y.A. Mokhtar M.N. Ya’acob M.E. Mohd G.H. Chang L.S. Manaf Y.N. Coconut (Cocos nucifera L.) sap as a potential source of sugar: Antioxidant and nutritional properties Food Sci. Nutr. 2019 8 1777 1787 10.1002/fsn3.1191 32328243 PMC7174220 · DOI
  45. [52]Santos J.L. Bispo V.S. Filho A.B. Pinto I.F. Dantas L.S. Vasconcelos D.F. Abreu F.F. Melo D.A. Matos I.A. Freitas F.P. Evaluation of chemical constituents and antioxidant activity of coconut water (Cocus nucifera L.) and caffeic acid in cell culture An. Acad. Bras. Cienc. 2013 85 1235 1247 10.1590/0001-37652013105312 24141413 · DOI · Paper page
  46. [53]Gulcin İ. Antioxidants and antioxidant methods: An updated overview Arch. Toxicol. 2020 94 651 715 10.1007/s00204-020-02689-3 32180036 · DOI · Paper page
  47. [54]Tiwari P.M. Role of flavonoids in DNA damage and carcinogenesis prevention J. Carcinog. Mutagen. 2017 8 4 10.4172/2157-2518.1000297 · DOI

Cited by

Sorted by citations

Authors
Phonphoem, W., Sinthuvanich, C., Aramrak, A., Sirichiewsakul, S., Arikit, S., & Yokthongwattana, C.
Affiliations
Kasetsart University (TH)
Corresponding author
Yokthongwattana, Chotika
Venue
Foods
Publisher
MDPI AG
Published
2022-12-04
Volume
11
Issue
23
Pages
3912
ISSN
2304-8158 (ISSN-L)
OpenAlex
W4311287228
Cited by
30
References
1
Citations by year
2026: 4 · 2025: 10 · 2024: 9 · 2023: 7
FWCI
2.05
Type
journal article
Language
en
Open access
Locations
  • Foods (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Kasetsart University Research and Development Institute (KURDI) (FF (KU) 10.65)
Topics
  • Physical Sciences › Chemistry › Inorganic Chemistry › Coconut Research and Applications
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
coconut meat, coconut water, nutritional composition, phytochemicals, antioxidant activity, DNA damage protection, medium-chain fatty acids, dietary fiber, phenolic compounds, flavonoids, nutraceuticals

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review