Topical PDT in the Treatment of Benign Skin Diseases: Principles and New Applications
Open accessAbstract
Photodynamic therapy (PDT) uses a photosensitizer, light energy, and molecular oxygen to cause cell damage. Cells exposed to the photosensitizer are susceptible to destruction upon light absorption because excitation of the photosensitizing agents leads to the production of reactive oxygen species and, subsequently, direct cytotoxicity. Using the intrinsic cellular heme biosynthetic pathway, topical PDT selectively targets abnormal cells, while preserving normal surrounding tissues. This selective cytotoxic effect is the basis for the use of PDT in antitumor treatment. Clinically, PDT is a widely used therapeutic regimen for oncologic skin conditions such as actinic keratosis, squamous cell carcinoma in situ, and basal cell carcinoma. PDT has been shown, under certain circumstances, to stimulate the immune system and produce antibacterial, and/or regenerative effects while protecting cell viability. Thus, it may be useful for treating benign skin conditions. An increasing number of studies support the idea that PDT may be effective for treating acne vulgaris and several other inflammatory/infective skin diseases, including psoriasis, rosacea, viral warts, and aging-related changes. This review provides an overview of the clinical investigations of PDT and discusses each of the essential aspects of the sequence: its mechanism of action, common photosensitizers, light sources, and clinical applications in dermatology. Of the numerous clinical trials of PDT in dermatology, this review focuses on those studies that have reported remarkable therapeutic benefits following topical PDT for benign skin conditions such as acne vulgaris, viral warts, and photorejuvenation without causing severe side effects.
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For the treatment of acne, the total dose of red light needs to be adjusted for FST.
“For the treatment of acne, the total dose of red light needs to be adjusted for FST as discussed by multiple authors for patients of Asian origin.65,118–120”
From Effect of skin color on optical properties and the implications for medical optical technologies: a review (2024) · cites this paper as [120]
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The present and future role of photodynamic therapy in cancer treatment
Brown, S. B., Brown, E. A., & Walker, I. O. (2004) · The Lancet Oncology · doi:10.1016/s1470-2045(04)01529-3 · Cited by 1,772 · see citing works
Photodynamic therapy with endogenous protoporphyrin
Kennedy, J. C., Pottier, R. H., & Pross, D. C. (1990) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(90)85083-9 · Cited by 1,509 · see citing works
Photoradiation therapy for the treatment of malignant tumors.
Dougherty, T. J., Kaufman, J., Goldfarb, A., Weishaupt, K. R., Boyle, D. G., & Mittleman, A. (1978) · PubMed · Cited by 1,487 · see citing works
Thiboutot, D. M., Gollnick, H. P. M., Bettoli, V., Dréno, B., Kang, S., Leyden, J. J., Shalita, A. R., Lozada, V. T., Berson, D. S., Finlay, A. Y., et al. (2009) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2009.01.019 · Cited by 839 · see citing works
Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy
Nyman, E., & Hynninen, P. H. (2003) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2003.10.002 · Cited by 714 · see citing works
Cell Death Pathways in Photodynamic Therapy of Cancer
Mróz, P., Yaroslavsky, A., Kharkwal, G. B., & Hamblin, M. R. (2011) · Cancers · doi:10.3390/cancers3022516 · Cited by 709 · see citing works
Braathen, L. R., Szeimies, R., Basset‐Séguin, N., Bissonnette, R., Foley, P. A., Pariser, D. M., Roelandts, R., Wennberg, A., & Morton, C. A. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2006.06.006 · Cited by 658 · see citing works
Topical ALA-Photodynamic Therapy for the Treatment of Acne Vulgaris
Hongcharu, W., Taylor, C. R., Aghassi, D., Suthamjariya, K., Anderson, R. R., & Chang, Y. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00046.x · Cited by 527 · see citing works
Szeimies, R. (2002) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(02)00056-7 · Cited by 434 · see citing works
Ashkenazi, H., Malik, Z., Harth, Y., & Nitzan, Y. (2003) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2003.tb00644.x · Cited by 374 · see citing works
Morton, C. A., Szeimies, R. ‐., Sidoroff, A., & Braathen, L. R. (2013) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12031 · Cited by 344 · see citing works
Divaris, D. X. G., Kennedy, J. C., & Pottier, R. (1990) · PubMed · Cited by 321 · see citing works
Pariser, D. M., Lowe, N. J., Stewart, D. M., Jarratt, M. T., Lucky, A. W., Pariser, R. J., & Yamauchi, P. S. (2003) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2003.49 · Cited by 302 · see citing works
James, W. D. (2005) · New England Journal of Medicine · doi:10.1056/nejmcp033487 · Cited by 268 · see citing works
Current evidence and applications of photodynamic therapy in dermatology
Lin, J., & Wan, M. T. (2014) · Clinical, Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s35334 · Cited by 248 · see citing works
Stender, I., Na, R., Fogh, H., Gluud, C. N., & Wulf, H. C. (2000) · The Lancet · doi:10.1016/s0140-6736(00)90013-8 · Cited by 242 · see citing works
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin
Iinuma, S., Farshi, S., Ortel, B., & Hasan, T. (1994) · British Journal of Cancer · doi:10.1038/bjc.1994.244 · Cited by 240 · see citing works
Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate
Wiegell, S. R., & Wulf, H. C. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.12.033 · Cited by 216 · see citing works
Itoh, Y., Ninomiya, Y., Tajima, S., & Ishibashi, A. (2001) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2001.04086.x · Cited by 203 · see citing works
Kawada, A., Aragane, Y., Kameyama, H., Sangen, Y., & Tezuka, T. (2002) · Journal of Dermatological Science · doi:10.1016/s0923-1811(02)00068-3 · Cited by 199 · see citing works
Tarstedt, M., Rosdahl, I., Berne, B., Svanberg, K., & Wennberg, A. (2005) · Acta Dermato-Venereologica · doi:10.1080/00015550510032887 · Cited by 196 · see citing works
Fritsch, C., Homey, B., Stahl, W., Lehmann, P., Ruzicka, T., & Sies, H. (1998) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1998.tb02492.x · Cited by 192 · see citing works
Recent overview of the Mg branch of the tetrapyrrole biosynthesis leading to chlorophylls
Masuda, T. (2008) · Photosynthesis Research · doi:10.1007/s11120-008-9291-4 · Cited by 183 · see citing works
Dirschka, T., Radny, P., Dominicus, R., Mensing, H., Brüning, H., Jenne, L., Karl, L., Sebastian, M., Oster‐Schmidt, C., Klövekorn, W., et al. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10613.x · Cited by 182 · see citing works
Diagnosis and treatment of acne.
Feldman, S. R., Careccia, R. E., Barham, K. L., & Hancox, J. G. (2004) · PubMed · Cited by 162 · see citing works
Photodynamic therapy for acne vulgaris: A critical review from basics to clinical practice
Sakamoto, F. H., Lopes, J. D., & Anderson, R. R. (2010) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2009.09.056 · Cited by 150 · see citing works
Gold, M. H., Bradshaw, V. L., Boring, M. M., Bridges, T. M., & Biron, J. A. (2006) · Dermatologic Surgery · doi:10.1111/j.1524-4725.2006.32163.x · Cited by 147 · see citing works
Wiegell, S. R. (2003) · Archives of Dermatology · doi:10.1001/archderm.139.9.1173 · Cited by 142 · see citing works
Photodynamic Therapy for Acne Vulgaris With Topical 5-Aminolevulinic Acid
Itoh, Y., Ninomiya, Y., Tajima, S., & Ishibashi, A. (2000) · Archives of Dermatology · doi:10.1001/archderm.136.9.1093 · Cited by 139 · see citing works
Wang, X. L., Wang, H. W., Wang, H. S., Xu, S., Liao, K. H., & Hillemanns, P. (2004) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2004.06189.x · Cited by 135 · see citing works
Yeung, C. K., Shek, S. Y. N., Bjerring, P., Yu, C. S., Kono, T., & Chan, H. H. L. (2007) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20469 · Cited by 132 · see citing works
Moloney, F. J., & Collins, P. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.07946.x · Cited by 128 · see citing works
Chen, K., Chang, B. Z., Ju, M., Zhang, M., & Gu, H. (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2006.07648.x · Cited by 123 · see citing works
Molecular Effects of Photodynamic Therapy for Photoaging
Orringer, J. S., Hammerberg, C., Hamilton, T. A., Johnson, T. M., Kang, S., Sachs, D. L., Fisher, G. J., & Voorhees, J. J. (2008) · Archives of Dermatology · doi:10.1001/archderm.144.10.1296 · Cited by 117 · see citing works
Kwon, H. H., Lee, J. B., Yoon, J. Y., Park, S. Y., Ryu, H. H., Park, B. M., Kim, Y. J., & Suh, D. H. (2012) · British Journal of Dermatology · doi:10.1111/bjd.12186 · Cited by 115 · see citing works
Rojanamatin, J., & CHOAWAWANICH, P. (2006) · Dermatologic Surgery · doi:10.1111/j.1524-4725.2006.32221.x · Cited by 115 · see citing works
Stender, I., Lock‐Andersen, J., & Wulf, H. C. (1999) · Clinical and Experimental Dermatology · doi:10.1046/j.1365-2230.1999.00441.x · Cited by 113 · see citing works
Photodynamic therapy of primary nonmelanomatous skin tumours of the head and neck
K�bler, A. C., Haase, T., Staff, C., Kahle, B. K., Rheinwald, M., & M�hling, J. (1999) · Lasers in Surgery and Medicine · doi:10.1002/(sici)1096-9101(1999)25:1 · Cited by 111 · see citing works
Current Evidence and Applications of Photodynamic Therapy in Dermatology
(2015) · Journal of the Dermatology Nurses’ Association · doi:10.1097/jdn.0000000000000135 · Cited by 109 · see citing works
Phototherapy and acne vulgaris
Cunliffe, W. J., & Goulden, V. (2000) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2000.03528.x · Cited by 107 · see citing works
Karrer, S., Bosserhoff, A., Weiderer, P., Landthaler, M., & Szeimies, R. (2004) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2004.06209.x · Cited by 106 · see citing works
Goldman, M. P., & Boyce, S. M. (2003) · PubMed · Cited by 106 · see citing works
KUIJPERS, D. I. M., Thissen, M. R. T. M., Thissen, C. A. C. B., & NEUMANN, M. H. A. M. (2006) · PubMed · Cited by 102 · see citing works
Ultrastructural changes seen after ALA‐IPL photorejuvenation: A pilot study
Marmur, E. S., Phelps, R. G., & Goldberg, D. J. (2005) · Journal of Cosmetic and Laser Therapy · doi:10.1080/147641700510037725 · Cited by 97 · see citing works
ROSS, E. V., ROMERO, R., Kollias, N., Crum, C. P., & Anderson, R. R. (1997) · British Journal of Dermatology · doi:10.1046/j.1365-2133.1997.19442059.x · Cited by 83 · see citing works
Borelli, C., Merk, K., Schaller, M., Jacob, K., Vogeser, M., Weindl, G., Berger, U., & Plewig, G. (2006) · Acta Dermato Venereologica · doi:10.2340/00015555-0088 · Cited by 79 · see citing works
Fehr, M. K., Chapman, C. F., Krasieva, T. B., Tromberg, B. J., McCullough, J. L., Berns, M. W., & Tadir, Y. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70332-0 · Cited by 78 · see citing works
Itkin, A., & Gilchrest, B. A. (2004) · Dermatologic Surgery · doi:10.1111/j.1524-4725.2004.30317.x · Cited by 77 · see citing works
Fluorescence from pilosebaceous follicles
Johnsson, A., Kjeldstad, B., & Mel�, T. B. (1987) · Archives of Dermatological Research · doi:10.1007/bf00413256 · Cited by 75 · see citing works
Bissonnette, R., Tremblay, J.-F., Lui, H., Juzenas, P., & Boushira, M. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01827.x · Cited by 71 · see citing works
Photodynamic therapy of cervical intraepithelial neoplasia grades II and III with Photolon®
Istomin, Y. P., Lapzevich, T. P., Chalau, V. N., Shliakhtsin, S. V., & Trukhachova, T. V. (2010) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2010.06.005 · Cited by 70 · see citing works
Diagnosis and treatment of acne.
Titus, S. J., & Hodge, J. (2012) · PubMed · Cited by 68 · see citing works
Enk, C. D., Nasereddin, A., Alper, R., Dan‐Goor, M., Jaffe, C. L., & Wulf, H. C. (2014) · British Journal of Dermatology · doi:10.1111/bjd.13490 · Cited by 67 · see citing works
Topical aminolevulinic acid‐photodynamic therapy for the treatment of acne vulgaris
Hong, S., & Lee, M. (2005) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2005.00181.x · Cited by 64 · see citing works
Szeimies, R., Schleyer, V., Moll, I., Stocker, M., Landthaler, M., & Karrer, S. (2009) · Dermatologic Surgery · doi:10.1111/j.1524-4725.2009.01125.x · Cited by 62 · see citing works
Liang, J. F., Lu, X. N., Tang, H., Zhang, Z., Fan, J., & Xu, J. H. (2009) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2009.00467.x · Cited by 61 · see citing works
Self-assembled liposomal nanoparticles in photodynamic therapy
Sadasivam, M., Avci, P., Gupta, G. K., Lakshmanan, S., Chandran, R., Huang, Y., Kumar, R., & Hamblin, M. R. (2013) · European Journal of Nanomedicine · doi:10.1515/ejnm-2013-0010 · Cited by 61 · see citing works
Successful treatment of periungual warts using photodynamic therapy: a pilot study
Schroeter, C. A., Kaas, L., Waterval, J. J., Bos, P., & Neumann, H. A. M. (2007) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2007.02081.x · Cited by 60 · see citing works
Jin, Y., Zhang, X., Zhang, B., Kang, H., Du, L., & Li, M. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.02.038 · Cited by 59 · see citing works
Photodynamic therapy for cosmetic applications
Uebelhoer, N. S., & Dover, J. S. (2005) · Dermatologic Therapy · doi:10.1111/j.1529-8019.2005.05023.x · Cited by 58 · see citing works
Ichimura, H., Yamaguchi, S., Kojima, A., Tanaka, T., Niiya, K., Takemori, M., Hasegawa, K., & Nishimura, R. (2003) · International Journal of Clinical Oncology · doi:10.1007/s10147-003-0354-4 · Cited by 57 · see citing works
Hypericin-loaded lipid nanocapsules for photodynamic cancer therapy in vitro
Barras, A., Boussekey, L., Courtade, E., & Boukherroub, R. (2013) · Nanoscale · doi:10.1039/c3nr02724d · Cited by 57 · see citing works
Jang, M. S., Doh, K. ‐., Kang, J. S., Jeon, Y. S., Suh, K. S., & Kim, S. T. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2011.10472.x · Cited by 56 · see citing works
Successful Treatment of Cutaneous Sarcoidosis Using Topical Photodynamic Therapy
Karrer, S. (2002) · Archives of Dermatology · doi:10.1001/archderm.138.5.581 · Cited by 56 · see citing works
Diagnosis and Treatment of Acne
Philpott, J. A. (1955) · Postgraduate Medicine · doi:10.1080/00325481.1955.11711801 · Cited by 56 · see citing works
ROSS, E. V., ROMERO, R., Kollias, N., et al. (1997) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1997.tb01110.x · Cited by 56 · see citing works
Aesthetic effects of topical photodynamic therapy
Kohl, E. A., Torezan, L. A. R., Landthaler, M., & Szeimies, R. (2010) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2010.03625.x · Cited by 55 · see citing works
Photodynamic Therapy and Fluorescence Diagnosis of Skin Cancers
Szeimies, R., & Landthaler, M. (2002) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-642-59410-6_28 · Cited by 54 · see citing works
Babilas, P., Travnik, R., Werner, A., Landthaler, M., & Szeimies, R. (2007) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/j.1610-0387.2007.06555.x · Cited by 52 · see citing works
Casas, A., Perotti, C., Saccoliti, M., Sacca, P., Fukuda, H., & del C Batlle, A. M. (2002) · British Journal of Cancer · doi:10.1038/sj.bjc.6600144 · Cited by 52 · see citing works
Characterisation of liposomes containing aminolevulinic acid and derived esters
Venosa, G. M. D., Bruno, L. H., Batlle, A. M. D. C., Fukuda, H., Tesoriero, M. V. D., Mamone, L. A., Rodríguez, L., MacRobert, A. J., & Casas, A. G. (2008) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2008.03.008 · Cited by 49 · see citing works
Ying, Z., Li, X., & Dang, H. (2013) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12043 · Cited by 46 · see citing works
Efficacy of Topical Aminolevulinic Acid Photodynamic Therapy for the Treatment of Verruca Planae
Lu, Y., Wu, J., He, Y., Yang, H.-Z., & Yang, Y. (2009) · Photomedicine and Laser Surgery · doi:10.1089/pho.2009.2566 · Cited by 45 · see citing works
Successful treatment of topical photodynamic therapy using 5-aminolevulinic acid for plane warts
Mizuki, D., Kaneko, T., & Hanada, K. (2003) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2003.05617.x · Cited by 42 · see citing works
Nucci, V., Torchia, D., & Cappugi, P. (2010) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2009.11.031 · Cited by 42 · see citing works
Combination ALA‐PDT and ablative fractional Er:YAG laser (2,940 nm) on the treatment of severe acne
Yin, R., Lin, L., Yan, X. H., Hao, F., & Hamblin, M. R. (2014) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22219 · Cited by 41 · see citing works
In Vitro Fungicidal Photodynamic Effect of Hypericin on Trichophyton spp
Paz-Cristobal, M. P., Gilaberte, Y., Alejandre, C., Pardo, J., Revillo, M. J., & Rezusta, A. (2014) · Mycopathologia · doi:10.1007/s11046-014-9797-6 · Cited by 41 · see citing works
Wang, J., Xu, J., Chen, J., He, Q., Li, X., Huang, X.-M., Ding, G., & Xu, S. (2009) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-009-1335-2 · Cited by 36 · see citing works
Piffaretti, F. M., Zellweger, M., Kasraee, B., Barge, J., Salomon, D., van den Bergh, H., & Wagnières, G. (2013) · Dermatology · doi:10.1159/000353775 · Cited by 35 · see citing works
Xiang, W., Weingandt, H., Ließmann, F., Klein, S., Stepp, H. G., Baumgartner, R., & Hillemanns, P. (2001) · Photochemistry and Photobiology · doi:10.1562/0031-8655(2001)0740617peibaa2.0.co2 · Cited by 33 · see citing works
Ma, Y., Liu, Y., Wang, Q., Ren, J., & Xiang, L. F. (2015) · The Journal of Dermatology · doi:10.1111/1346-8138.12836 · Cited by 29 · see citing works
Pilot study on photodynamic therapy for acne using indocyanine green and diode laser
Kim, B. J., Lee, H. G., Woo, S. M., Youn, J. I., & Suh, D. H. (2009) · The Journal of Dermatology · doi:10.1111/j.1346-8138.2008.00580.x · Cited by 28 · see citing works
Barge, J., Glanzmann, T. M., Zellweger, M., Salomon, D., van den Bergh, H., & Wagnières, G. (2013) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2013.08.005 · Cited by 26 · see citing works
Applications of Aminolevulinic Acid-Based Photodynamic Therapy in Cosmetic Facial Plastic Practices
Zakhary, K., & Ellis, D. A. F. (2005) · Facial Plastic Surgery · doi:10.1055/s-2005-872411 · Cited by 25 · see citing works
Clinical Aspects of Photodynamic Therapy
Barr, H., Kendall, C. A., Reyes-Goddard, J., & Stone, N. (2002) · Science Progress · doi:10.3184/003685002783238825 · Cited by 23 · see citing works
Shin, H., Kim, J. H., Shim, J., Lee, J. H., Lee, D., Lee, J. H., & Yang, J. M. (2014) · Journal of Dermatological Treatment · doi:10.3109/09546634.2014.933163 · Cited by 22 · see citing works
Chong, W., & Kang, G. Y. M. (2009) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2009.00439.x · Cited by 16 · see citing works
Gold, M. H. (2008) · PubMed · Cited by 14 · see citing works
Pilot study on photodynamic therapy for acne using chlorophyll: Evaluator-blinded, split-face study
Kim, J. E., Hwang, J. I., Lee, J. I., Cho, B. K., & Park, H. J. (2011) · Journal of Dermatological Treatment · doi:10.3109/09546634.2010.514598 · Cited by 14 · see citing works
Self-citationKim, J. E., Kim, S. J., Hwang, J. I., Lee, K. J., Park, H. J., & Cho, B. K. (2011) · Journal of Dermatological Treatment · doi:10.3109/09546634.2010.551534 · Cited by 11 · see citing works
Self-citationNontraditional management of basal cell carcinoma.
Botto, N. C., & Rogers, G. S. (2013) · PubMed · Cited by 11 · see citing works
A mathematical evaluation of dose-dependent PpIX fluorescence kinetics in vivo
Chatelain (2001) · Pure Amsterdam UMC · doi:10.1562/0031-8655(2001)074 · Cited by 6 · see citing works
Gold, M. H., & Pope, A. (2008) · PubMed · Cited by 3 · see citing works
Szeimiesa, R. M., Karrera, S., Radakovic-Fijanb, S., et al. (2002) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2002.119649
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Macrophages During the Fibrotic Process: M2 as Friend and Foe
Braga, T. T., Agudelo, J. S. H., & Câmara, N. O. S. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00602 · Cited by 462 · see citing works
A clinical review of phototherapy for psoriasis
Zhang, P., & Wu, M. X. (2017) · Lasers in Medical Science · doi:10.1007/s10103-017-2360-1 · Cited by 304 · see citing works
Trends and targets in antiviral phototherapy
Wiehe, A., O’Brien, J. M., & Senge, M. O. (2019) · Photochemical & Photobiological Sciences · doi:10.1039/c9pp00211a · Cited by 257 · see citing works
The potential of photodynamic therapy (PDT)—Experimental investigations and clinical use
Oniszczuk, A., Wojtunik‐Kulesza, K. A., Oniszczuk, T., & Kasprzak‐Drozd, K. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.07.058 · Cited by 214 · see citing works
Recent advances in innovative strategies for enhanced cancer photodynamic therapy
Hu, T., Wang, Z., Shen, W., Liang, R., Yan, D., & Wei, M. (2021) · Theranostics · doi:10.7150/thno.54227 · Cited by 210 · see citing works
Hypericin in the Light and in the Dark: Two Sides of the Same Coin
Jendželovská, Z., Jendželovský, R., Kuchárová, B., & Fedoročko, P. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00560 · Cited by 188 · see citing works
Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment
Khorsandi, K., Hosseinzadeh, R., Esfahani, H., Zandsalimi, K., Shahidi, F. K., & Abrahamse, H. (2022) · Inflammation and Regeneration · doi:10.1186/s41232-022-00226-6 · Cited by 184 · see citing works
Soumya, K., More, N., Choppadandi, M., Aishwarya, D. A., Singh, G., & Kapusetti, G. (2023) · Biomedical Technology · doi:10.1016/j.bmt.2023.01.005 · Cited by 136 · see citing works
Photodynamic therapy with nanoparticles to combat microbial infection and resistance
Bekmukhametova, A., Ruprai, H., Hook, J. M., Mawad, D., Houang, J., & Lauto, A. (2020) · Nanoscale · doi:10.1039/d0nr04540c · Cited by 124 · see citing works
Malatesti, N., Munitić, I., & Jurak, I. (2017) · Biophysical Reviews · doi:10.1007/s12551-017-0257-7 · Cited by 120 · see citing works
Liu, F., Li, Z., Cao, B., Wu, J., Wang, Y., Xue, Y., Xu, J., Xue, C., & Tang, Q. J. (2016) · Food Research International · doi:10.1016/j.foodres.2016.07.012 · Cited by 83 · see citing works
de Annunzio, S. R., Costa, N. C. S., Mezzina, R. D., Graminha, M. A. S., & Fontana, C. R. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163861 · Cited by 78 · see citing works
Wang, Y., Fu, S., Lu, Y., Lai, R., Liu, Z., Luo, W., & Xu, Y. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118819 · Cited by 74 · see citing works
Setchfield, K., Gorman, A., Simpson, A. H. R. W., Somekh, M. G., & Wright, A. J. (2024) · Journal of Biomedical Optics · doi:10.1117/1.jbo.29.1.010901 · Cited by 72 · see citing works
Nanoparticle Systems for Cancer Phototherapy: An Overview
Pivetta, T. P., Botteon, C. E. A., Ribeiro, P. A., Marcato, P. D., & Raposo, M. (2021) · Nanomaterials · doi:10.3390/nano11113132 · Cited by 70 · see citing works
Daylight Photodynamic Therapy for Actinic Keratoses
Morton, C. A., & Braathen, L. R. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0360-y · Cited by 65 · see citing works
de Annunzio, S. R., de Freitas, L. M., Blanco, A. L., da Costa, M. M., Carmona‐Vargas, C. C., de Oliveira, K. T., & Fontana, C. R. (2017) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2017.11.035 · Cited by 60 · see citing works
Recent advances in nanoparticle-based targeting tactics for antibacterial photodynamic therapy
Moore, B., del Valle, C. A., Field, R. A., & Marín, M. J. (2022) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-022-00194-3 · Cited by 58 · see citing works
Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals
Hashim, G. M., Shahgolzari, M., Hefferon, K. L., Yavari, A., & Venkataraman, S. (2024) · Bioengineering · doi:10.3390/bioengineering12010007 · Cited by 50 · see citing works
Mohanty, S., Desai, V. M., Jain, R., Agrawal, M., Dubey, S. K., & Singhvi, G. (2024) · RSC Advances · doi:10.1039/d4ra02564d · Cited by 47 · see citing works
Photodynamic therapy for rosacea in Chinese patients
Fan, L., Yin, R., Lan, T., & Hamblin, M. R. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.08.005 · Cited by 43 · see citing works
Photodynamic evaluation of tetracarboxy-phthalocyanines in model systems
Alonso, L., Sampaio, R. N., de Souza, T. F. M., Silva, R. C., Neto, N., Ribeiro, A. O., Alonso, A., & Gonçalves, P. J. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.05.008 · Cited by 42 · see citing works
Photodynamic Therapy Is Effective Against Candida auris Biofilms
Bapat, P. S., & Nobile, C. J. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.713092 · Cited by 36 · see citing works
Immune consequences induced by photodynamic therapy in non-melanoma skin cancers: a review
Yu, X., Zheng, H., Chan, M. T. V., & Wu, W. K. K. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-018-2426-z · Cited by 33 · see citing works
Photophysical properties and therapeutic use of natural photosensitizers
Gonçalves, L. C. P. (2021) · Journal of Photochemistry and Photobiology · doi:10.1016/j.jpap.2021.100052 · Cited by 31 · see citing works
Bapat, P. S., Singh, G., & Nobile, C. J. (2021) · Microorganisms · doi:10.3390/microorganisms9030500 · Cited by 30 · see citing works
Metal complexes of tridentate tripod ligands in medical imaging and therapy
Silva, F., Fernandes, C., Campello, M. P. C., & Paulo, A. (2016) · Polyhedron · doi:10.1016/j.poly.2016.11.040 · Cited by 29 · see citing works
Cai, Q., Yang, L., Chen, J., Yang, H. W., Gao, Z., & Wang, X. (2018) · Mycopathologia · doi:10.1007/s11046-018-0267-4 · Cited by 28 · see citing works
Li, Z., Teng, M., Wang, Y., Wang, Q., Feng, Y., Xiao, Z., Li, C., & Zeng, K. (2021) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12663 · Cited by 25 · see citing works
MAL‐PDT inhibits oral precancerous cells and lesions via autophagic cell death
Wang, Y., Chen, Y.-K., Hu, S. C., Xiao, L., Huang, W., Chi, T., Cheng, K., Wang, Y., & Yuan, S. F. (2019) · Oral Diseases · doi:10.1111/odi.13036 · Cited by 24 · see citing works
Zeng, L., Zou, Q., Huang, P., Xiong, L., Cheng, Y., Chen, Q., Li, Y., He, H., Yi, W., & Wei, W. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111994 · Cited by 23 · see citing works
Shin, H., Kim, J. H., Shim, J., Lee, J. H., Lee, D., Lee, J. H., & Yang, J. M. (2014) · Journal of Dermatological Treatment · doi:10.3109/09546634.2014.933163 · Cited by 22 · see citing works
Shakhova, M. A., Kurakina, D. A., Meller, A., Sapunov, D., Orlinskaya, N. Y., Shakhov, A. V., Khilov, A. V., & Kirillin, M. (2018) · Journal of Biomedical Optics · doi:10.1117/1.jbo.23.9.091412 · Cited by 23 · see citing works
Carbonaceous nanomaterials for phototherapy: a review
Gürbüz, B., Ayan, S., Bozlar, M., & Üstündağ, C. B. (2020) · Emergent Materials · doi:10.1007/s42247-020-00118-w · Cited by 23 · see citing works
Photodynamic therapy for the treatment of complex anal fistula
Antonio Arroyo, S., Moya, P., Rodríguez-Prieto, M. Á., Alcaide, M. J., Aguilar, M.-D.-M., Bellon, M. C., Pérez-Vázquez, M. T., Candela, F. J. C., & Calpena, R. (2017) · Techniques in Coloproctology · doi:10.1007/s10151-016-1571-y · Cited by 22 · see citing works
Photodynamic Therapy for Photodamage, Actinic Keratosis, and Acne in the Cosmetic Practice
Moy, L. S., Frost, D., & Moy, S. (2019) · Facial Plastic Surgery Clinics of North America · doi:10.1016/j.fsc.2019.09.012 · Cited by 22 · see citing works
Ebani, P. R., Stefanello, L. B., Kuhn, B. L., Frizzo, C. P., Burgo, T. A. L., Kloster, C. L., & Villetti, M. A. (2021) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2021.116874 · Cited by 22 · see citing works
ALA‐PDT alleviates the psoriasis by inhibiting JAK signalling pathway
Fei, Y., Zheng, X., Fang, F., Zhang, J., Zhou, B., & Chen, X. (2019) · Experimental Dermatology · doi:10.1111/exd.14017 · Cited by 21 · see citing works
Huang, K., Xie, Y., Li, M., Liu, D., Su, J., Li, F., Deng, B., Li, J., Shi, W., Zhang, J., et al. (2020) · Lasers in Surgery and Medicine · doi:10.1002/lsm.23212 · Cited by 21 · see citing works
Kirillin, M., Kurakina, D. A., Khilov, A. V., Orlova, A., Shakhova, M. A., Orlinskaya, N. Y., & Sergeeva, E. A. (2020) · Biomedical Optics Express · doi:10.1364/boe.411518 · Cited by 20 · see citing works
Kurokawa, H., Ito, H., & Matsui, H. (2019) · Cells · doi:10.3390/cells8080918 · Cited by 20 · see citing works
An insight into photodynamic therapy towards treating major dermatological conditions
Dey, A., Singhvi, G., Puri, A., Kesharwani, P., & Dubey, S. K. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.103751 · Cited by 19 · see citing works
On the population of triplet states of 2-seleno-thymine
Valverde, D., Mai, S., de Araújo, A. V. S., Canuto, S., González, L., & Borin, A. C. (2021) · Physical Chemistry Chemical Physics · doi:10.1039/d1cp00041a · Cited by 18 · see citing works
Hur, G., Ryu, A., Kim, Y., & Lee, M. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14050968 · Cited by 18 · see citing works
Novel Chemotherapeutic Agents - The Contribution of Scorpionates
Andrade, M. A., & Martins, L. M. D. R. S. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180914104237 · Cited by 17 · see citing works
Ayaz, F., Demirbağ, B., & Ocakoğlu, K. (2020) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2020.102034 · Cited by 15 · see citing works
Fiber Lasers and Their Medical Applications
Gursel, A. T. (2018) · InTech eBooks · doi:10.5772/intechopen.76610 · Cited by 14 · see citing works
Photodynamic Therapy for the Treatment of Complex Anal Fistula
Antonio Arroyo, S., Sánchez‐Guillén, L., Parra, P. A., García‐Catalá, L., Ros, E. P., Márquez, M. F., Riera, C. N., Barber, X., & Simó, M. R. (2019) · Lasers in Surgery and Medicine · doi:10.1002/lsm.23162 · Cited by 14 · see citing works
Effects of high and low level 1265 nm laser irradiation on HCT116 cancer cells
Khokhlova, A. V., Золотовский, И. О., Stoliarov, D. A., Vorsina, S., Pogodina, E., Liamina, D., Fotiadi, A. A., Sokolovski, S. G., Saenko, Y., & Урихаевич, Р. Э. (2019) · Mechanisms of Photobiomodulation Therapy · doi:10.1117/12.2509529 · Cited by 14 · see citing works
Barbosa, M. I. F., Parra, G. G., Corrêa, R. S., Sampaio, R. N., Magno, L. N., Silva, R. C., Doriguetto, A. C., Ellena, J., Neto, N., Batista, A. A., et al. (2017) · Journal of Photochemistry and Photobiology A Chemistry · doi:10.1016/j.jphotochem.2017.01.028 · Cited by 14 · see citing works
Photodynamic therapy, a promising treatment approach for cutaneous infectious granulomas
Yang, Z., Liu, C., Xiong, H., & Shi, D. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.102952 · Cited by 13 · see citing works
Wu, C., Qiu, X., He, C., & Ci, C. (2022) · BioMed Research International · doi:10.1155/2022/1220889 · Cited by 13 · see citing works
Towards dosimetry for photodynamic diagnosis with the low-level dose of photosensitizer
Buzalewicz, I., Hołowacz, I., Ulatowska-Jarża, A., & Podbielska, H. (2017) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2017.06.007 · Cited by 13 · see citing works
Cui, Z., Zhang, M., Geng, S., Niu, X., Wang, X., Zhu, Y., Ye, F., & Liu, C. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.749106 · Cited by 12 · see citing works
Photomodulation Approaches to Overcome Antimicrobial Resistance
Sarabando, S. N., Palmeira, A., Sousa, E., Faustino, M. A. F., & Monteiro, C. J. P. (2023) · Pharmaceuticals · doi:10.3390/ph16050682 · Cited by 12 · see citing works
The application of medical scale in the treatment of plantar warts: analysis and prospect
Huang, K., Li, M., Xiao, Y., Wu, L., Li, Y., Yang, Y., Shi, G., Yu, N., Liu, D., Su, J., et al. (2020) · Journal of Dermatological Treatment · doi:10.1080/09546634.2020.1781757 · Cited by 12 · see citing works
Huang, K., Li, Y., Zeng, W., Jiang, Z., Zhu, W., Chen, M., Deng, B., Su, J., & Zhao, S. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.05.040 · Cited by 12 · see citing works
Song, W., Zhang, J., Gao, N., Tan, W., Wang, G., & Gao, L. (2019) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2019.03.002 · Cited by 11 · see citing works
Topical 5-aminolevulinic acid photodynamic therapy for recalcitrant facial flat warts
Zhang, W., Zhao, J., Gao, T., Li, F., Wang, W., Zeng, X., & Li, Q. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103934 · Cited by 10 · see citing works
Effects of curcumin‐based photodynamic method on protein degradation of oysters
Lu, N., Wang, Z., Zhang, X., Liu, F., Gao, Y., Li, Z., Xue, C., & Tang, Q. (2021) · International Journal of Food Science & Technology · doi:10.1111/ijfs.15029 · Cited by 9 · see citing works
Pradeep, M., & Franklin, G. (2022) · Industrial Crops and Products · doi:10.1016/j.indcrop.2022.114876 · Cited by 9 · see citing works
Hu, C., Luo, X., Jiang, C., Lei, S., & Sun, Y. (2023) · Dermatologic Surgery · doi:10.1097/dss.0000000000003784 · Cited by 9 · see citing works
Recent Patents in anti-wart Treatment
Shahid, S. K. (2020) · Pharmaceutical Patent Analyst · doi:10.4155/ppa-2019-0028 · Cited by 9 · see citing works
AlGhamdi, A. S., Qamar, Z., AlSheikh, R., Hinai, M. T. A. A., Abdul, N. S., Aljoghaiman, E. A., & Ali, S. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.103258 · Cited by 9 · see citing works
Photoactivated cell-killing amino-based flavylium compounds
Oliveira, H., Araújo, P., Pereira, A. R., Mateus, N. F. D. C. B., de Freitas, V. A. P., Oliveira, J., & Fernandes, I. (2021) · Scientific Reports · doi:10.1038/s41598-021-01485-y · Cited by 7 · see citing works
Zhang, W., Wu, S., Wang, X., Pan, W., & Yan, Z. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.102819 · Cited by 7 · see citing works
Phototoxic Potential of Different DNA Intercalators for Skin Cancer Therapy: In Vitro Screening
Pivetta, T. P., Vieira, T., Silva, J. A. M. D. C., Ribeiro, P. A., & Raposo, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065602 · Cited by 7 · see citing works
Nunes, I. P. F., de Jesus, R. S., Almeida, J. A., Costa, W. L. R., Malta, M., Soares, L. G. P., de Almeida, P. F., & Pinheiro, A. L. B. (2024) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2024.112943 · Cited by 6 · see citing works
Karbasi, M., Varzandeh, M., Karbasi, M., Mobarakeh, A. I., Falahati, M., & Hamblin, M. R. (2024) · Nano-Structures & Nano-Objects · doi:10.1016/j.nanoso.2024.101315 · Cited by 6 · see citing works
Recent Advances in Combination Therapy of YAP Inhibitors with Physical Anti-Cancer Strategies
Zhou, J., Yu, C., Yang, W., Jiang, N., Li, S., Liu, Y., & Zhu, X. (2025) · Biomolecules · doi:10.3390/biom15070945 · Cited by 6 · see citing works
Applications of photodynamic therapy in keratitis
Anwar, A., Khan, N. A., Alharbi, A. M., Alhazmi, A. S., & Siddiqui, R. (2024) · International Ophthalmology · doi:10.1007/s10792-024-03062-4 · Cited by 5 · see citing works
Scarabello, A., Pulvirenti, C., Adebanjo, G. A. R., Parisella, F. R., Chello, C., & Tammaro, A. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.102794 · Cited by 5 · see citing works
Pereira, F., de Annunzio, S. R., Lopes, T. D. A., de Oliveira, K. T., Cilli, E. M., Barbugli, P. A., & Fontana, C. R. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.103104 · Cited by 5 · see citing works
Differential Photosensitivity of Fibroblasts Obtained from Normal Skin and Hypertrophic Scar Tissues
Kusumoto, J., Akashi, M., Terashi, H., & Sakakibara, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042126 · Cited by 5 · see citing works
Ryu, A., & Lee, M. (2019) · Molecular & Cellular Toxicology · doi:10.1007/s13273-019-0030-z · Cited by 5 · see citing works
Nanocarriers for Photodynamic Therapy Intended to Cutaneous Tumors
Pierre, M. B. R. (2021) · Current Drug Targets · doi:10.2174/1389450122999210101230743 · Cited by 5 · see citing works
The Innate Immune System and Fever under Redox Control: A Narrative Review
Szőke, H., Bókkon, I., David, M. W., Vagedes, J., Kiss, Á., Kovács, Z., Fekete, F., Kocsis, T., Szijjártó, L., Adam, D., et al. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220203122239 · Cited by 5 · see citing works
Antitumor immune responses induced by photodynamic and sonodynamic therapy: a narrative review
Chen, H., & Dai, Z. (2020) · Journal of Bio-X Research · doi:10.1097/jbr.0000000000000080 · Cited by 4 · see citing works
Yu, W., Fu, J., Chen, Y., Mu, Y., Jin, Q., Wang, Y., & Ji, J. (2025) · Materials Horizons · doi:10.1039/d5mh00253b · Cited by 4 · see citing works
From reactive oxygen to cancer cell death: the science behind photodynamic therapy
Gheybi, E., Hosseinzadeh, P., Tayebi-Khorrami, V., Rostami, M., & Soukhtanloo, M. (2025) · Lasers in Medical Science · doi:10.1007/s10103-025-04707-1 · Cited by 4 · see citing works
Tampa, M. Ş., Sârbu, M. I., Mitran, M. I., Mitran, C. I., Dumitru, A., Benea, V., & Georgescu, S. R. (2016) · Journal of Mind and Medical Sciences · doi:10.22543/2392-7674.1038 · Cited by 4 · see citing works
Hally, C., Rodríguez-Amigo, B., Bresolí‐Obach, R., Planas, O., Nos, J., Boix‐Garriga, E., Ruiz‐González, R., & Nonell, S. (2018) · Royal Society of Chemistry eBooks · doi:10.1039/9781788010597-00086 · Cited by 4 · see citing works
Photodynamic therapy for recalcitrant plantar warts: Case reports and a literature review.
Zhang, Y., Wu, S., & Zeng, Y. (2024) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2024.104087 · Cited by 4 · see citing works
Xie, K., Cheng, M., He, B., Li, W., & Zhong, W. (2024) · Indian Journal of Dermatology · doi:10.4103/ijd.ijd_524_22 · Cited by 3 · see citing works
Pecourneau, J., Losantos, R., Gansmüller, A., Parant, S., Bernhard, Y., Mourer, M., Monari, A., & Pasc, A. (2022) · Journal of Photochemistry and Photobiology A Chemistry · doi:10.1016/j.jphotochem.2023.114583 · Cited by 3 · see citing works
Serra-Guillén, C., Llombart, B., & Sanmartín, O. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13092658 · Cited by 3 · see citing works
Photodynamic therapy in cosmetics
Dey, A., Kesharwani, P., & Dubey, S. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85595-2.00016-5 · Cited by 3 · see citing works
Chota, A., George, B. P. A., & Abrahamse, H. (2023) · Translational Biophotonics: Diagnostics and Therapeutics · doi:10.1117/12.2675917 · Cited by 3 · see citing works
Photosensitizing Properties of the Topical Retinoid Drug Adapalene
Soler-Orenes, J. A., Rodríguez‐Muñiz, G. M., Hernández‐Gil, J., Miranda, M. A., Andreu, I., & Lhiaubet‐Vallet, V. (2024) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.4c00384 · Cited by 3 · see citing works
Topical aminolevulinic acid–photodynamic therapy in the treatment of keratoacanthoma: A case report
Lv, T., Miao, F., Wu, M., Nie, S., Li, S., Wang, X., & Wang, H. (2018) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2018.06.005 · Cited by 3 · see citing works
Haag, R., Gurow, O., Mack, M., Moisel, J., & Heßling, M. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18010072 · Cited by 2 · see citing works
Feng, X., Fan, H., Zhou, L., Zhao, Z., Mu, Y., Sun, X., & Chen, Y. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.102872 · Cited by 2 · see citing works
Lima, A. C. V. D. O., Holanda, V. M., Mazza, M. R., Oliveira, G. D. F. S., Fantini, M. C. D. A., Oliveira, C. L. P., Sousa, E. H. S., de Araújo, T. G., Eloy, J. O., & Petrilli, R. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.127226 · Cited by 2 · see citing works
Han, L., Jiang, Y., & Wan, M. (2024) · Journal of Dermatological Treatment · doi:10.1080/09546634.2024.2368066 · Cited by 2 · see citing works
Thala, K., Machina, A., Parveen, S., & Ramana, L. N. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.114301 · Cited by 2 · see citing works
Wang, F., Li, L., & Xu, S. (2025) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2025.104583 · Cited by 2 · see citing works
Kadbhane, A. S., Dahikar, S. B., & Bhutada, S. A. (2025) · Asian Journal of Research in Pharmaceutical Sciences · doi:10.52711/2231-5659.2025.00023 · Cited by 2 · see citing works
Curcumin and Nanocurcumin in the Treatment of Photodynamic Therapy for Skincare
(2022) · Letters in Applied NanoBioScience · doi:10.33263/lianbs124.092 · Cited by 2 · see citing works
Anatomically Adjustable Device for Large-Area Photodynamic Therapy
Fujita, A. K. L., Chianfrone, D. J., Moreira, V. S., Zanchin, A. L., de Menezes, P. F. C., & Bagnato, V. S. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.93917 · Cited by 2 · see citing works
Recent Advances in Cobalt Derived Complexes as Potential Therapeutic Agents
Malik, M. A., Dar, O. A., & Hashmi, A. A. (2020) · doi:10.1002/9781119640868.ch5 · Cited by 2 · see citing works
- Authors
- Kim, M., Jung, H., & Park, H.
- Affiliations
- The Catholic University of Korea Yeouido St. Mary's Hospital (KR)
- Corresponding author
- Park, Hyun
- ORCID
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2015-09-25
- Volume
- 16
- Issue
- 10
- Pages
- 23259-23278
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC4632697
- OpenAlex
- W2155002081
- Cited by
- 133
- References
- 96
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 15 · 2023: 8 · 2022: 15 · 2021: 16 · 2020: 11 · 2019: 14 · 2018: 14 · 2017: 7 · 2016: 8 · 2015: 1 · 2014: 1
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- National Research Foundation
- National Research Foundation of Korea (2012046972)
- Ministry of Education, Science and Technology (2012046972)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Health Sciences › Medicine › Epidemiology › Nonmelanoma Skin Cancer Studies
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Keywords
- photodynamic therapy, topical photodynamic therapy, benign skin disease, photosensitizers, reactive oxygen species, heme biosynthesis, acne, viral warts, photorejuvenation, psoriasis, rosacea, actinic keratosis, Bowen's disease, basal cell carcinoma, light sources, immunostimulation
- MeSH terms
- Administration, Cutaneous, Female, Humans, Male, Photochemotherapy, Skin Diseases, Photosensitizing Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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