Two Coiled-Coil Proteins, WEB1 and PMI2, Suppress the Signaling Pathway of Chloroplast Accumulation Response that Is Mediated by Two Phototropin-Interacting Proteins, RPT2 and NCH1, in Seed Plants
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Chloroplast movement is induced by blue light in a broad range of plant species. Weak light induces the chloroplast accumulation response and strong light induces the chloroplast avoidance response. Both responses are essential for efficient photosynthesis and are mediated by phototropin blue-light receptors. J-DOMAIN PROTEIN REQUIRED FOR CHLOROPLAST ACCUMULATION RESPONSE 1 (JAC1) and two coiled-coil domain proteins WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 1 (WEB1) and PLASTID MOVEMENT IMPAIRED 2 (PMI2) are required for phototropin-mediated chloroplast movement. Genetic analysis suggests that JAC1 is essential for the accumulation response and WEB1/PMI2 inhibit the accumulation response through the suppression of JAC1 activity under the strong light. We recently identified two phototropin-interacting proteins, ROOT PHOTOTROPISM 2 (RPT2) and NPH3/RPT2-like (NRL) PROTEIN FOR CHLOROPLAST MOVEMENT 1 (NCH1) as the signaling components involved in chloroplast accumulation response. However, the relationship between RPT2/NCH1, JAC1 and WEB1/PMI2 remained to be determined. Here, we performed genetic analysis between RPT2/NCH1, JAC1, and WEB1/PMI2 to elucidate the signal transduction pathway.
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WEB1/PMI2 inhibit accumulation responses by inhibiting JAC1 activity under high light.
“WEB1/PMI2 inhibited accumulation responses by inhibiting JAC1 activity under high light”
From The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants (2022) · cites this paper as Suetsugu and Wada, 2017
The Results and Discussion says WEB1/PMI2 repress the accumulation-response pathway under strong light and hypothesizes that they do so by suppressing JAC1 function. It also says how WEB1 and PMI2 suppress that pathway remains to be determined, so the claim presents a proposed mechanism as established. (LLM, conf=0.88)
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“Furthermore, WEB1/PMI2 inhibited accumulation responses by inhibiting JAC1 activity under high light (Suetsugu and Wada, 2017).”
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- Authors
- Suetsugu, N., & Wada, M.
- Affiliations
- Kyoto University (JP)
- Tokyo Metropolitan University (JP)
- Corresponding author
- Suetsugu, Noriyuki
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2017-07-08
- Volume
- 18
- Issue
- 7
- Pages
- 1469
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC5535960
- OpenAlex
- W2725293919
- Cited by
- 7
- References
- 17
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2018: 1
- FWCI
- 0.27
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Institutional Repositories DataBase (IRDB) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Kyoto University Research Information Repository (Kyoto University) (submittedVersion, cc-by)
- Funders
- Japan Society for the Promotion of Science (16K14758)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- phototropin, blue light signaling, coiled-coil proteins, Rpt2, signal transduction, chloroplast movement, weak light, seed plants
- MeSH terms
- Carrier Proteins, Chloroplasts, Light, Plant Proteins, Plants, Signal Transduction, Arabidopsis Proteins, Phototropins
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