The DOI matches its Crossref record; 170 of the 170 references it cites were found in a registry or an index.
Biological Activities of Stilbenoids
Open accessAbstract
Stilbenoids are a group of naturally occurring phenolic compounds found in various plant species. They share a common backbone structure known as stilbene, but differ in the nature and position of substituents. Stilbenoids are classified as phytoalexins, which are antimicrobial compounds produced de novo in plants to protect against fungal infection and toxins. In this review, the biological effects of stilbenoids such as resveratrol, pterostilbene, gnetol and piceatannol are discussed. Stilbenoids exert various biological activities ranging from cardioprotection, neuroprotection, anti-diabetic properties, depigmentation, anti-inflammation, cancer prevention and treatment. The results presented cover a myriad of models, from cell culture to animal studies as well as clinical human trials. Although positive results were obtained in most cell culture and animal studies, further human studies are needed to substantiate beneficial effects of stilbenoids. Resveratrol remains the most widely studied stilbenoid. However, there is limited information regarding the potential of less common stilbenoids. Therefore, further research is warranted to evaluate the salutary effects of various stilbenoids.
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2 retracted
Pharmacological preconditioning with resveratrol: role of nitric oxide
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RetractedResveratrol improves health and survival of mice on a high-calorie diet
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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
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HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
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Cited by
Teka, T., Zhang, L., Ge, X., Li, Y., Han, L., & Yan, X. (2022) · Phytochemistry · doi:10.1016/j.phytochem.2022.113128 · Cited by 216
Engineering cyanobacteria for the production of aromatic natural products
Gu, F., Li, C., Zheng, H., & Ni, J. (2024) · Blue Biotechnology · doi:10.1186/s44315-024-00002-w · Cited by 9
Metadata
- Authors
- Akinwumi, B., Bordun, K.-A., & Anderson, H.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2018-03-09
- Volume
- 19
- Issue
- 3
- Pages
- 792
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2793327795
- Cited by
- 373
- References
- 170
- FWCI
- 16.60
- Type
- journal article
- Language
- en
- Open access
- gold
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- Akinwumi, B., Bordun, K.-A., & Anderson, H. (2018). Biological Activities of Stilbenoids. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms19030792
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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