The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Mechanisms of Blood–Brain Barrier Dysfunction in Traumatic Brain Injury
Open accessAbstract
Traumatic brain injuries (TBIs) account for the majority of injury-related deaths in the United States with roughly two million TBIs occurring annually. Due to the spectrum of severity and heterogeneity in TBIs, investigation into the secondary injury is necessary in order to formulate an effective treatment. A mechanical consequence of trauma involves dysregulation of the blood–brain barrier (BBB) which contributes to secondary injury and exposure of peripheral components to the brain parenchyma. Recent studies have shed light on the mechanisms of BBB breakdown in TBI including novel intracellular signaling and cell–cell interactions within the BBB niche. The current review provides an overview of the BBB, novel detection methods for disruption, and the cellular and molecular mechanisms implicated in regulating its stability following TBI.
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Cites
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Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders
Cohen, J., Mathew, A., Dourvetakis, K. D., Sanchez-Guerrero, E., Pangeni, R. P., Gurusamy, N., Aenlle, K. K., Ravindran, G., Twahir, A., Isler, D., et al. (2024) · Cells · doi:10.3390/cells13060511 · Cited by 103
Li, J., Wei, Y., Zhang, C., Bi, R., Qiu, Y., Li, Y., & Hu, B. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15020621 · Cited by 85
Boyko, M., Gruenbaum, B. F., Frank, D., Natanel, D., Negev, S., Azab, A. N., Barsky, G., Knyazer, B., Kofman, O., & Zlotnik, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065897 · Cited by 27
Vargas-Rodríguez, P., Cuenca-Martagón, A., Castillo-González, J., Serrano-Martínez, I., Luque, R. M., Delgado, M., & González-Rey, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814117 · Cited by 25
Cai, M., Chen, S., Du, Y., Li, S., Dong, P., Wang, L., Yang, R., Hu, J., & Zhu, L. (2022) · Journal of Molecular Neuroscience · doi:10.1007/s12031-022-02052-4 · Cited by 4
Metadata
- Authors
- Cash, A., & Theus, M. H.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-05-08
- Volume
- 21
- Issue
- 9
- Pages
- 3344
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3023520239
- Cited by
- 318
- References
- 26
- FWCI
- 9.01
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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