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Cited by 615

The DOI matches its Crossref record; 181 of the 181 references it cites were found in a registry or an index.

Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis

Open access
Molnar, Vilim, Matišić, Vid, Kodvanj, Ivan, Bjelica, Roko, Jeleč, Željko, Hudetz, Damir, Rod, Eduard, Čukelj, Fabijan, Vrdoljak, Trpimir, Vidović, Dinko, Starešinić, Mario, Sabalić, Srećko, Dobričić, Borut, Petrović, Tadija, Antičević, Darko, Borić, Igor, Košir, Rok, Zmrzljak, Uršula Prosenc, Primorac, Dragan·2021·International Journal of Molecular Sciences

Abstract

Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The pathogenesis of this degenerative process is not completely understood; however, a low-grade inflammation leading to an imbalance between anabolic and katabolic processes is a well-established factor. The complex network of cytokines regulating these processes and cell communication has a central role in the development and progression of osteoarthritis. Concentrations of both proinflammatory and anti-inflammatory cytokines were found to be altered depending on the osteoarthritis stage and activity. In this review, we analyzed individual cytokines involved in the immune processes with an emphasis on their function in osteoarthritis.

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Metadata

Authors
Molnar, V., Matišić, V., Kodvanj, I., Bjelica, R., Jeleč, Ž., Hudetz, D., Rod, E., Čukelj, F., Vrdoljak, T., Vidović, D., Starešinić, M., Sabalić, S., Dobričić, B., Petrović, T., Antičević, D., Borić, I., Košir, R., Zmrzljak, U. P., & Primorac, D.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2021-08-26
Volume
22
Issue
17
Pages
9208
ISSN
1422-0067 (ISSN-L)
OpenAlex
W3193501355
Cited by
615
References
181
FWCI
53.56
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis. https://app.cochat.ai/papers/10.3390/ijms22179208
The paper
Molnar, V., Matišić, V., Kodvanj, I., Bjelica, R., Jeleč, Ž., Hudetz, D., Rod, E., Čukelj, F., Vrdoljak, T., Vidović, D., Starešinić, M., Sabalić, S., Dobričić, B., Petrović, T., Antičević, D., Borić, I., Košir, R., Zmrzljak, U. P., & Primorac, D. (2021). Cytokines and Chemokines Involved in Osteoarthritis Pathogenesis. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22179208

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.