Aryl Hydrocarbon Receptor in Oxidative Stress as a Double Agent and Its Biological and Therapeutic Significance

Free radicals and antioxidants in normal physiological functions and human disease

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Free Radicals in the Physiological Control of Cell Function

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Oxidants, oxidative stress and the biology of ageing

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How mitochondria produce reactive oxygen species

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The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

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Oxidative stress, inflammation, and cancer: How are they linked?

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Oxyl radicals, redox-sensitive signalling cascades and antioxidants

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Oxidative Stress: Harms and Benefits for Human Health

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

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Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

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Regulating Reactive Oxygen Species in Rheumatoid Arthritis: Insights into Cell Signaling Pathways and Nano-Particles as Carriers

Srinivasan, T., Ashok, P., Sairam, V., & Reddy, A. (2024) · Biochemistry · doi:10.5772/intechopen.113191

Immunomodulatory Effect of Nuciferine on Benzo(a)pyrene (B[a]P)-induced Lung Cancer: A Preclinical Model

Li, F., Luan, X., Yao, Y., & Cao, X. (2025) · Pharmacognosy Magazine · doi:10.1177/09731296251318787

Modulation of the effects of a cholesterol-supplemented high-fat diet by aryl hydrocarbon receptor (AHR) activation and/or tryptophan reduction in male mice

Bathina, A. R., Hakanen, J., Raasmaja, A., Lindén, J., Mairinoja, L., Unniappan, S., Pettersson, L., & Pohjanvirta, R. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.102083

Potential protective effects of Pistacia lentiscus L. var. latifolius coss extract against carbon tetrachloride-induced liver injury: Biochemical, histopathological, and computational insights

Ragab, A. E., Afify, S. R. E., Al‐Ashmawy, G. M., & Abo-Saif, M. A. (2025) · Fitoterapia · doi:10.1016/j.fitote.2025.106773

Approach to topical treatment of mild-to-moderate atopic dermatitis: A physician assistant perspective

DiRuggiero, D., Trickett, C., Cheever, E., Dalphon, G., Sangha, A. M., Sturm, D., & Blackburn, T. (2025) · Journal of Dermatology for Physician Assistants · doi:10.1097/jdpa.0000000000000081

The Cellular Effects of Di(2-ethylhexyl) Phthalate in Non-Malignant Colonic Epithelia Involve Oxidative Stress

Bomstein, Z. S., Allred, K. F., & Allred, C. D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311716

Black tea extract exerts a protective effect on diethylnitrosamine-induced hepatic precancerous lesions through the Nrf2 signaling pathway

Wang, X., Hu, Y.-H., Luo, J.-J., & Wang, Y. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.103260

From Nutritional Epidemiology to Clinical Translation: Machine Learning Uncovers Antioxidant-Driven Prevention Strategies for Mitigating Cardiovascular-Arthritis Multimorbidity

Di, J., Song, L., Long, Y., Zhao, Y., Guo, Z., Qin, Y., & 向川 (2025) · Antioxidants and Redox Signaling · doi:10.1177/15230864251401537

Identification of aryl hydrocarbon receptor as a functional target that enhances astrocytic ApoE secretion

Donovan, K. W., Stefan, E., Bajrami, B., Bennion, M., Huff, S., Mustafa, D. N., Su, M.-J., Dragan, S., Sciabola, S., Chou, Y.-Y., et al. (2026) · Cell chemical biology · doi:10.1016/j.chembiol.2025.12.005

Aryl hydrocarbon receptor-mediated transcriptional regulation of HSP70 exacerbates endoplasmic reticulum stress in lupus nephritis

Wen, M., Li, J., Li, Y., Hun, M., Yang, T., Meng, Y., Liu, L., Gong, H., Yu, Y., Zhang, Z., et al. (2026) · Cell & Bioscience · doi:10.1186/s13578-026-01547-6

An Ecofriendly L-Tryptophan Containing UVA-1 Permissive Sunscreen Formulation: A Novel Approach for Inflammatory and Fibrosing Skin Diseases

Noakes, R. (2026) · International Journal of Tryptophan Research · doi:10.1177/11786469261416785

Keratinocytes exposed to Ozone induce a bystander oxinflammatory response in dermal fibroblasts

Sarandy, M. M., Guiotto, A., Ivarsson, J., Pecorelli, A., & Valacchi, G. (2026) · Toxicology · doi:10.1016/j.tox.2026.154447

Ionizing Radiation as a Factor in Neurodegeneration: Current Insights into Pathogenesis and Consequences

Iztleuov, M., Ryzhkin, S., Smagulova, G., Saparbaev, S., Iztleuov, Y. M., Abugaliyeva, N., & Gaydullayeva, A. (2026) · Медицинский журнал Западного Казахстана · doi:10.4103/wkmj.wkmj_24_26

Precision environmental medicine: Integrated multi‐exposure transcriptomics for shared molecular networks in COPD pathogenesis in response to environmental exposure

Rahim, F., Akpınar, G., & Dzhusupov, K. O. (2026) · Precision Medical Sciences · doi:10.1002/prm2.70037

The global research landscape and frontiers of endocrine-disrupting chemicals-induced vascular toxicity: A bibliometric and visualization analysis

Kang, T., Zhang, F., Zheng, J., Yong, X., & Ismail, N. A. (2026) · Eurasian Journal of Medicine and Oncology · doi:10.36922/ejmo026050050

Molecular mechanism of dopaminergic neuron injury induced by PAHs: Regulation of AhR-RORα/Nrf2 axis and α-syn O-GlcNAc modification

Gao, Y., Duan, C., Zheng, X., & Qu, L. (2026) · NeuroToxicology · doi:10.1016/j.neuro.2026.103494

Ligand-specific duality of aryl hydrocarbon receptor signaling in cognitive health: from environmental neurotoxicity to microbiome-mediated neuroprotection

Tian, C., Yang, S., Zhang, X., & Yan, H. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1823961

Metabolism-Driven Modulation by the Human Microbiota: Implications for Cancer Therapy and Emerging Strategies

Gouveia, L., Serpa, J., & Mendes, C. (2026) · Advances in experimental medicine and biology · doi:10.1007/978-3-032-12166-0_3

Pharmacogenomics and Personalized Medicine: Applications in Environmental Toxicology

Kumar, V., Sharma, S., Arulsamy, S., Wadhwa, P. K., & Kalra, R. (2026) · Springer eBooks · doi:10.1007/978-3-032-28619-2_12

Food preservative tBHQ modulates Th17/Treg balance through AHR/NRF2 xenosensors and increases the sensitivity of T cells to activation stimuli

Palczert, Z., Németh, K., Fekete, N., Pállinger, É., Márta, B.-K., Petschner, P., Buzás, E. I., Csala, M., & Tamási, V. (2026) · Current Research in Toxicology · doi:10.1016/j.crtox.2026.100314

Distinct DNA hydroxymethylation landscape and mitochondrial DNA rearrangement signatures induced by single- and multi-fraction alpha particle radiation in lung fibroblasts

Vera-Chang, M. N., Danforth, J. M., Stuart, M., Brand, M., Goodarzi, A. A., & Richardson, R. B. (2026) · Current Zoology · doi:10.1093/eep/dvag020

Environmental and genetic interactions in autism spectrum disorder: a literature review with a focus on air pollution

Ayyan, M., Salameh, H., Alladaboina, S., Ayoub, S., Subai, A., Naimi, H. A., Khan, A. S., Yousef, M., Pal, M., & Châari, A. (2026) · Environmental Health · doi:10.1186/s12940-026-01321-8

Systemic redox switching of transcription factors: A context-sensitive framework for cell fate decisions

Dimova, E. Y., & Kietzmann, T. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104348

Acute toxic effects and molecular mechanisms of combined pollution by microplastics and petroleum on Tegillarca granosa in intertidal sediments based on biochemical indicators, histopathology, DNA damage and gene expression

Pan, Y., Xia, C., Chai, X., Yang, J., Qian, J., Zhou, K., & Qian, W. (2026) · Environmental Research · doi:10.1016/j.envres.2026.125479

Naphthenic acids induce developmental cardiotoxicity in marine medaka (Oryzias melastigma) embryos through an AhR-associated oxidative stress cascade

Chu, J., Cui, S., Zhang, Y., Kong, Q., Zhou, Y., Wang, Y., Xia, Y., & Zhang, H. (2026) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2026.101549

Aryl hydrocarbon receptor (AhR) regulates organic dust and organic dust-associated bacterial extracellular vesicles-induced airway inflammation via ROS-dependent NFκB and STAT3 activation

Meganathan, V., Kusampudi, S., Stenhouse, M., & Boggaram, V. (2026) · Respiratory Research · doi:10.1186/s12931-026-03908-8

Aryl Hydrocarbon Receptor (Ahr) Pathway Drives TBBPA Induced Cartilage Development DefectsPreprint

Pathirajage, K. S., Sharma, S., Johnson, T., Sarker, A., & Dasgupta, S. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.07.749921

Burdock (Arctium lappa L.) Root Extract Induces Transcriptional Signatures Associated with Metal Homeostasis and Lipid Metabolism in Human Keratinocytes

Bender, C., Suarez, C. G., Habarta, A., Blainski, A., Ruggiero, A., & Stornaiuolo, M. (2026) · Metabolites · doi:10.3390/metabo16100707

2,8-Dihydroxyquinoline ameliorates oligoasthenozoospermia by inhibiting MAPK14-mediated spermatogonial ferroptosis

Fu, W., Wu, S., Yongting, Y., Lin, M., Duan, M., Wu, W., & 游旭军 (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12786-8

Evaluation of Hepatotoxic and Nephrotoxic Effects of Hexachlorobenzene, DDT , and p,p′‐ DDE in Rats

Keshim, K., Erdogan, C. S., Yaba, A., Sümer, E., & Yılmaz, B. (2026) · Environmental Toxicology · doi:10.1002/tox.70200

Para-Phenylenediamine Activates AhR and Nrf2 Pathways With Asymmetric Nrf2-to-AhR Crosstalk in HaCaT Keratinocytes

Lee, J. J., Cho, K., Jeong, K., Woo, S., Byun, J. Y., Choi, Y. W., Roh, J. Y., & Choi, H. Y. (2026) · Annals of Dermatology · doi:10.5021/ad.26.121

Benzene and cigarette smoke co-exposure exacerbates hematotoxicity involving the AhR–NLRP3 signaling pathway

Han, L., Liu, B., Xu, Z., Yang, X., Ning, Q., Jia, Q., He, J., & Wang, Y. (2026) · Toxicology Reports · doi:10.1016/j.toxrep.2026.102361

Induction of cellular oxidative stress by aryl hydrocarbon receptor activation

Dalton, T. P., Puga, A., & Shertzer, H. G. (2002) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(02)00067-4 · Cited by 188

Antioxidant Functions of the Aryl Hydrocarbon Receptor

Dietrich, C. (2016) · Stem Cells International · doi:10.1155/2016/7943495 · Cited by 148

Influence of oxidative stress on aryl hydrocarbon receptor signaling

Mohammadi‐Bardbori, A. (2013) · Figshare · Cited by 2

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

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An introduction to the molecular basics of aryl hydrocarbon receptor biology

Abel, J., & Haarmann‐Stemmann, T. (2010) · Biological Chemistry · doi:10.1515/bc.2010.128 · Cited by 309