Association between Sarcopenic Obesity, Type 2 Diabetes, and Hypertension in Overweight and Obese Treatment-Seeking Adult Women
Open accessAbstract
The last decade has seen a new condition that describes the coexistence of obesity and sarcopenia, termed sarcopenic obesity (SO). We aimed to assess the prevalence of SO in overweight and obese treatment-seeking adult women and the association with type 2 diabetes, hypertension, and dyslipidemia. A body composition assessment was conducted with an InBody bioimpedance analyser in 154 overweight and obese women referred to the Outpatient Clinic in the Department of Nutrition and Dietetics at Beirut Arab University (BAU) in Lebanon, and 30 normal-weight participants of similar age. The overweight and obese patients were then categorized as being with or without sarcopenia. Thirty-one out of the 154 overweight or obese participants met the criteria for SO and displayed a significantly higher prevalence of type 2 diabetes and hypertension than those without SO. Logistic regression analysis showed that SO increases the odds of having type 2 diabetes and hypertension by nearly 550% (odds ratio = 5.42, 95% confidence interval = 1.37–21.40, p < 0.05) after adjusting for central fat, eating habits, level of physical activity, and smoking. SO affects nearly 20% of treatment-seeking overweight and obese adult women. Moreover, SO seems to be strongly associated with type 2 diabetes and hypertension.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Sarcopenic obesity has been reported in as many as 20% of young women aged 18 years or older seeking obesity treatment.
“which has been reported in as many as 20% of young women (≥18 years of age) seeking obesity treatment.”
From Strategies for minimizing muscle loss during use of incretin‐mimetic drugs for treatment of obesity (2025) · cites this paper as [18]
SO increases the odds of having T2D and hypertension by nearly 550% (OR=5.42, 95% CI: 1.37-21.40, P<0.05).
“Logistic regression analysis showed that SO increases the odds of having T2D and hypertension by nearly 550% [odds ratio (OR) = 5.42, 95% confidence interval (95% CI): 1.37–21.40, P < 0.05].[ 92 ]”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [92]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Toprak, Ö., Kurt, H., Sarı, Y., Şarkış, C., Us, H., & Kırık, A. (2017) · Kidney & Blood Pressure Research · doi:10.1159/000468530 · Cited by 29,769 · see citing works
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Sarcopenia: European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601 · see citing works
The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function
Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481 · see citing works
Health effects of overweight and obesity in 195 countries over 25 years
Collaborators, T. G. 2. O. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1614362 · Cited by 7,918 · see citing works
Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia
Chen, L.-K., Liu, L.-K., Woo, J., Assantachai, P., Auyeung, T.-W., Bahyah, K. S., Chou, M.-Y., Chen, L.-Y., Hsu, P.-S., Krairit, O., et al. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.11.025 · Cited by 4,051 · see citing works
Fielding, R. A., Vellas, B., Evans, W. J., Bhasin, S., Morley, J. E., Newman, A. B., Abellan van Kan, G., Andrieu, S., Bauer, J., Breuille, D., et al. (2011) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2011.01.003 · Cited by 3,256 · see citing works
Studenski, S. A., Peters, K. W., Alley, D. E., Cawthon, P. M., McLean, R. R., Harris, T. B., Ferrucci, L., Guralnik, J. M., Fragala, M. S., Kenny, A. M., et al. (2014) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glu010 · Cited by 2,545 · see citing works
Sarcopenic obesity: definition, cause and consequences
Stenholm, S., Harris, T. B., Rantanen, T., Visser, M., Kritchevsky, S. B., & Ferrucci, L. (2008) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e328312c37d · Cited by 1,070 · see citing works
Bouchard, D. R., Dionne, I. J., & Brochu, M. (2009) · Obesity · doi:10.1038/oby.2009.109 · Cited by 314 · see citing works
Sarcopenia in the elderly: Diagnosis, physiopathology and treatment
Malafarina, V., Úriz‐Otano, F., Iniesta, R. R., & Gil‐Guerrero, L. (2011) · Maturitas · doi:10.1016/j.maturitas.2011.11.012 · Cited by 297 · see citing works
Bredella, M. A., Ghomi, R. H., Thomas, B. J., Torriani, M., Brick, D. J., Gerweck, A. V., Misra, M., Klibanski, A., & Miller, K. K. (2010) · Obesity · doi:10.1038/oby.2010.5 · Cited by 201 · see citing works
Limitations and validation of bioelectrical impedance analysis in morbidly obese patients
Coppini, L. Z., Waitzberg, D. L., & Campos, A. C. L. (2005) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/01.mco.0000165013.54696.64 · Cited by 199 · see citing works
Body Composition Measured by Dual‐energy X‐ray Absorptiometry Half‐body Scans in Obese Adults
Rothney, M. P., Brychta, R. J., Schaefer, E. V., Chen, K. Y., & Skarulis, M. C. (2009) · Obesity · doi:10.1038/oby.2009.14 · Cited by 195 · see citing works
Sarcopenic obesity: how do we treat it?
Bouchonville, M. F., & Villareal, D. T. (2013) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/01.med.0000433071.11466.7f · Cited by 141 · see citing works
Limitation of a cross-sectional study.
Solem, R. C. (2015) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2015.05.006 · Cited by 141 · see citing works
Johnson Stoklossa, C. A., Sharma, A. M., Forhan, M., Siervo, M., Padwal, R. S., & Prado, C. M. (2017) · Journal of Nutrition and Metabolism · doi:10.1155/2017/7307618 · Cited by 121 · see citing works
Sarcopenic obesity and metabolic syndrome in adult Caucasian subjects
Poggiogalle, E., Lubrano, C., Sergi, G., Coin, A., Gnessi, L., Mariani, S., Lenzi, A., & Donini, L. M. (2016) · The Journal of nutrition, health and aging · doi:10.1007/s12603-015-0638-1 · Cited by 106 · see citing works
Assessing inflammatory status in cardiovascular disease
Tousoulis, D., Antoniades, C., & Stefanadis, C. (2007) · Heart · doi:10.1136/hrt.2006.088211 · Cited by 77 · see citing works
Physical performance measures in screening for reduced lean body mass in adult females with obesity
El Ghoch, M., Rossi, A. P., Calugi, S., Rubele, S., Soave, F., Zamboni, M., Chignola, E., Mazzali, G., Bazzani, P. V., & Dalle Grave, R. (2018) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2018.06.008 · Cited by 26 · see citing works
Sarcopenic Obesity: Definition, Health Consequences and Clinical Management
Ghoch, M. E., Calugi, S., & Grave, R. D. (2018) · The Open Nutrition Journal · doi:10.2174/1874288201812010070 · Cited by 26 · see citing works
The effect of sarcopenic obesity on cardiovascular disease and all-cause mortality in older people
Atkins, J. L., & Wannamethee, S. G. (2015) · Reviews in Clinical Gerontology · doi:10.1017/s0959259815000076 · Cited by 18 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review
Li, C., Yu, K., Shyh‐Chang, N., Jiang, Z., Liu, T., Ma, S., Luo, L., Guang, L., Liang, K., Ma, W., et al. (2022) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12901 · Cited by 626 · see citing works
Strategies for minimizing muscle loss during use of incretin‐mimetic drugs for treatment of obesity
Mechanick, J. I., Butsch, W. S., Christensen, S. M., Hamdy, O., Li, Z., Prado, C. M., & Heymsfield, S. B. (2025) · Obesity Reviews · doi:10.1111/obr.13841 · Cited by 149 · see citing works
Khadra, D., Itani, L., Tannir, H., Kreidieh, D., Masri, D. E., & Ghoch, M. E. (2019) · World Journal of Diabetes · doi:10.4239/wjd.v10.i5.311 · Cited by 130 · see citing works
Self-citationon behalf of the Special Interest Groups of Systematic Reviews and Meta-Analysis for Healthy Ageing, D., Veronese, N., Pizzol, D., Demurtas, J., Soysal, P., Smith, L., Sieber, C. C., Strandberg, T. E., Bourdel‐Marchasson, I., Sinclair, A. J., et al. (2019) · European Geriatric Medicine · doi:10.1007/s41999-019-00216-x · Cited by 79 · see citing works
Measuring Muscle Mass and Strength in Obesity: a Review of Various Methods
Sizoo, D., de Heide, L. J. M., Emous, M., van Zutphen, T., Navis, G., & van Beek, A. P. (2021) · Obesity Surgery · doi:10.1007/s11695-020-05082-2 · Cited by 77 · see citing works
Khazem, S., Itani, L., Kreidieh, D., Masri, D. E., Tannir, H., Citarella, R., & Ghoch, M. E. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15122754 · Cited by 47 · see citing works
Self-citationProkopidis, K., Daly, R. M., & Suetta, C. (2025) · The Journal of nutrition, health and aging · doi:10.1016/j.jnha.2025.100652 · Cited by 40 · see citing works
Ghoch, M. E., & Fakhoury, R. (2019) · Journal of Population Therapeutics and Clinical Pharmacology · doi:10.15586/jptcp.v26i2.599 · Cited by 40 · see citing works
Understanding Sarcopenic Obesity in Terms of Definition and Health Consequences: A Clinical Review
Nezameddin, R., Itani, L., Kreidieh, D., Masri, D. E., Tannir, H., & Ghoch, M. E. (2020) · Current Diabetes Reviews · doi:10.2174/1573399816666200109091449 · Cited by 38 · see citing works
Self-citationMusculoskeletal effects of obesity and bariatric surgery – a narrative review
de Holanda, N. C. P., Crispim, N., Carlos, I. D. L., Moura, T., Nóbrega, E., & Bandeira, F. A. F. (2022) · Archives of Endocrinology and Metabolism · doi:10.20945/2359-3997000000551 · Cited by 33 · see citing works
Lee, J. K., Park, Y. S., Kim, K., Oh, T. J., & Chang, W. (2021) · Obesity Surgery · doi:10.1007/s11695-021-05569-6 · Cited by 27 · see citing works
Tak, Y. J., Kim, Y. J., Lee, J. G., Yi, Y.-H., Cho, Y. H., Kang, G.-H., & Lee, S. Y. (2019) · Marine Drugs · doi:10.3390/md17030157 · Cited by 25 · see citing works
Rasaei, N., Kashavarz, S. A., Yekaninejad, M. S., & Mirzaei, K. (2019) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2019.06.023 · Cited by 24 · see citing works
The Risk of Sarcopenia among Adults with Normal-Weight Obesity in a Nutritional Management Setting
LORENZO, A. D., Pellegrini, M., Gualtieri, P., Itani, L., Ghoch, M. E., & Renzo, L. D. (2022) · Nutrients · doi:10.3390/nu14245295 · Cited by 22 · see citing works
Self-citationKreidieh, D., Itani, L., El Masri, D., Tannir, H., & El Ghoch, M. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00022 · Cited by 21 · see citing works
Self-citationBaalbaki, R., Itani, L., Kebbi, L. E., Dehni, R., Abbas, N., Farsakouri, R., Awad, D., Tannir, H., Kreidieh, D., Masri, D. E., et al. (2019) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd6020023 · Cited by 17 · see citing works
Self-citationYogesh, M., Patel, M., Makwana, H., & Kalariya, H. (2024) · Clinical Diabetes and Endocrinology · doi:10.1186/s40842-024-00179-4 · Cited by 16 · see citing works
Tannir, H., Kreidieh, D., Itani, L., Masri, D. E., & Ghoch, M. E. (2019) · Current Diabetes Reviews · doi:10.2174/1573399815666191030092138 · Cited by 16 · see citing works
Self-citationKumari, M., & Khanna, A. (2022) · Annals of Geriatric Medicine and Research · doi:10.4235/agmr.22.0081 · Cited by 16 · see citing works
Adiposity is inversely associated with strength in older adults with type 2 diabetes mellitus
Barrett, M., McClure, R., & Villani, A. M. (2020) · European Geriatric Medicine · doi:10.1007/s41999-020-00309-y · Cited by 15 · see citing works
Godziuk, K., Woodhouse, L. J., Prado, C. M. M., & Forhan, M. A. (2020) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2020.08.005 · Cited by 15 · see citing works
Yoo, T. K., Rhim, H. C., Lee, Y., Yoon, K. J., & Park, C. (2022) · Scientific Reports · doi:10.1038/s41598-022-16401-1 · Cited by 15 · see citing works
de Sá-Caputo, D. D. C., Sonza, A., Coelho-Oliveira, A. C., Pessanha-Freitas, J., dos Reis, A. S., Francisca-Santos, A., dos Anjos, E. M., Paineiras-Domingos, L. L., Guerra, T. D. R. B., Franco, A. D. S., et al. (2021) · Biology · doi:10.3390/biology10111209 · Cited by 15 · see citing works
Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19
Mayoral, L. P.-C., Matias‐Cervantes, C. A., Pérez‐Campos, E., Díaz, C. R., Barrios, L. Á. L., Pina-Canseco, M. D. S., Cruz, M. M., Mayoral, E. P., Solórzano-Mata, C. J., Canales, F. J. R., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158277 · Cited by 14 · see citing works
Luo, Y., Shu, L., Wang, Y., Zhao, X., Han, M., Liu, Y., Xu, Y. J., & Han, B. (2025) · International Journal of Obesity · doi:10.1038/s41366-025-01909-z · Cited by 13 · see citing works
The Association between Sarcopenic Obesity and DXA-Derived Visceral Adipose Tissue (VAT) in Adults
LORENZO, A. D., Itani, L., Ghoch, M. E., Frank, G., Santis, G. L. D., Gualtieri, P., & Renzo, L. D. (2024) · Nutrients · doi:10.3390/nu16111645 · Cited by 13 · see citing works
Self-citationMyostatin as a plausible biomarker for early stage of sarcopenic obesity
Ishibashi, C., Nakanishi, K., Nishida, M., Shinomiya, H., Shinzawa, M., Kanayama, D., Yamamoto, R., Kudo, T., Nagatomo, I., & Yamauchi‐Takihara, K. (2024) · Scientific Reports · doi:10.1038/s41598-024-79534-5 · Cited by 13 · see citing works
Kjønigsen, L. J., Harneshaug, M., Fløtten, A., Karterud, L. K., Petterson, K., Skjolde, G., Eggesbø, H. B., Weedon‐Fekjær, H., Henriksen, H. B., & Lauritzen, P. M. (2019) · European Radiology Experimental · doi:10.1186/s41747-019-0122-5 · Cited by 13 · see citing works
Itani, L., Kreidieh, D., Masri, D. E., Tannir, H., & Ghoch, M. E. (2020) · Current Diabetes Reviews · doi:10.2174/1573399816666200211102057 · Cited by 13 · see citing works
Self-citationPellegrini, M., Itani, L., Rossi, A. P., Kreidieh, D., El Masri, D., Tannir, H., & El Ghoch, M. (2022) · Healthcare · doi:10.3390/healthcare10102042 · Cited by 11 · see citing works
“In addition, SO seems to be a prevalent phenotype among females seeking weight management treatment [9].”
BackgroundInfluentialSelf-citationCarvalho, N., Martins, V. J. B., Filho, J. M., Bandeira, F. A. F., Pimenta, F. C. F., & Alves, J. L. D. B. (2019) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s213643 · Cited by 10 · see citing works
Masri, D. E., Itani, L., Tannir, H., Kreidieh, D., & Ghoch, M. E. (2021) · Clinics and Practice · doi:10.3390/clinpract11030069 · Cited by 8 · see citing works
Self-citationLORENZO, A. D., Itani, L., Gualtieri, P., Pellegrini, M., Ghoch, M. E., & Renzo, L. D. (2023) · Life · doi:10.3390/life14010021 · Cited by 8 · see citing works
Self-citationKreidieh, D., Itani, L., Tannir, H., Masri, D. E., & Ghoch, M. E. (2020) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd7010005 · Cited by 8 · see citing works
Self-citationGhoch, M. E., & Pellegrini, M. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.962895 · Cited by 6 · see citing works
Sarkopene Adipositas und Inflammation
Norman, K., & Herder, C. (2019) · Der Diabetologe · doi:10.1007/s11428-019-0456-x · Cited by 5 · see citing works
Itani, L., Tannir, H., Kreidieh, D., Masri, D. E., & Ghoch, M. E. (2020) · Journal of Population Therapeutics and Clinical Pharmacology · doi:10.15586/jptcp.v27i1.653 · Cited by 5 · see citing works
Self-citationGhoch, M. E., Rossi, A. P., Verde, L., Barrea, L., Muscogiuri, G., Savastano, S., & Colao, A. (2022) · Panminerva Medica · doi:10.23736/s0031-0808.22.04784-x · Cited by 4 · see citing works
Masri, D. E., Kreidieh, D., Tannir, H., Itani, L., & Ghoch, M. E. (2018) · Reports — Medical Cases Images and Videos · doi:10.3390/reports1030021 · Cited by 4 · see citing works
Self-citationAndreoli, B., Mantovani, A., & Andreoli, C. (2020) · Journal of Clinical and Translational Endocrinology Case Reports · doi:10.1016/j.jecr.2020.100061 · Cited by 4 · see citing works
Sasaki, H. (2019) · Food and Nutrition Sciences · doi:10.4236/fns.2019.109075 · Cited by 3 · see citing works
Marine Natural Products and Obesity
Urbatzka, R., & Vasconcelos, V. M. (2019) · MDPI eBooks · doi:10.3390/books978-3-03921-192-0 · Cited by 1 · see citing works
Nutrition, Genetics, and Cardiovascular Disease
Ghoch, M. E., & Shamieh, S. E. (2020) · MDPI eBooks · doi:10.3390/books978-3-03943-241-7
Sizoo, D. (2024) · doi:10.33612/diss.992833908
Grippa, P. C., Quesada, K. R., Barboza, G. D. O., Marvulle, M. E. G., Candido, D., Machado, N. M., Laurindo, L. F., Araújo, A. C., de Lima, E. P., Guiguer, É. L., et al. (2026) · Medicina · doi:10.3390/medicina62010182
Li, X., Zhao, Y., Liu, J., Wen, Z., Chen, Y., & Xie, W. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1881526
- Authors
- Kreidieh, D., Itani, L., El Masri, D., Tannir, H., Citarella, R., & El Ghoch, M.
- Affiliations
- Beirut Arab University (LB)
- Department of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, P.O. Box 11-5020 Riad El Solh, Beirut 11072809, Lebanon
- CTR Centre of Rehabilitation Therapy, 42124 Reggio Emilia, Italy
- Venue
- Journal of Cardiovascular Development and Disease
- Publisher
- MDPI AG
- Published
- 2018-10-20
- Volume
- 5
- Issue
- 4
- Pages
- 51
- ISSN
- 2308-3425 (ISSN-L)
- PMC
- PMC6306700
- OpenAlex
- W2896321133
- Cited by
- 46
- References
- 23
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2023: 1 · 2022: 9 · 2021: 3 · 2020: 10 · 2019: 12 · 2018: 2
- FWCI
- 4.64
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Journal of Cardiovascular Development and Disease (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Keywords
- sarcopenic obesity, sarcopenia, type 2 diabetes, hypertension, dyslipidemia, obesity, overweight women, body composition, bioimpedance, prevalence, comorbidities
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review