Sarcopenic obesity: how do we treat it?

Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society Clinical Practice Guideline

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A deletion in the bovine myostatin gene causes the double–muscled phenotype in cattle

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Effects of Human Growth Hormone in Men over 60 Years Old

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Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

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Weight loss, exercise, or both and physical function in obese older adults

Villareal, D. T., Chode, S., Parimi, N., Sinacore, D. R., Hilton, T., Armamento-Villareal, R., Napoli, N., Qualls, C., & Shah, K. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1008234 · Cited by 1,096 · see citing works

Sarcopenic Obesity Predicts Instrumental Activities of Daily Living Disability in the Elderly

Baumgartner, R. N., Wayne, S. J., Waters, D. L., Janssen, I., Gallagher, D., & Morley, J. E. (2004) · Obesity Research · doi:10.1038/oby.2004.250 · Cited by 937 · see citing works

Induction of Cachexia in Mice by Systemically Administered Myostatin

Zimmers, T. A., Davies, M. V., Koniaris, L. G., Haynes, P. A., Esquela‐Kerscher, A., Tomkinson, K. N., McPherron, A. C., Wolfman, N. M., & Lee, S. (2002) · Science · doi:10.1126/science.1069525 · Cited by 908 · see citing works

Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society

Villareal, D. T., Apovian, C. M., Kushner, R. F., & Klein, S. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.923 · Cited by 880 · see citing works

Dietary protein recommendations and the prevention of sarcopenia

Paddon-Jones, D., & Rasmussen, B. B. (2009) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32831cef8b · Cited by 823 · see citing works

Age-related decrease in physical activity and functional fitness among elderly men and women

Milanovic, Z., Jorgić, B., Trajković, N., Sporis, Pantelić, S., & James (2013) · Clinical Interventions in Aging · doi:10.2147/cia.s44112 · Cited by 779 · see citing works

Muscle strength and body mass index as long-term predictors of mortality in initially healthy men

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Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis

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Sarcopenic obesity and inflammation in the InCHIANTI study

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Older Men Are as Responsive as Young Men to the Anabolic Effects of Graded Doses of Testosterone on the Skeletal Muscle

Bhasin, S., Woodhouse, L., Casaburi, R., Singh, A. B., Mac, R. P., Lee, M., Yarasheski, K. E., Sinha-Hikim, I., Dzekov, C., Dzekov, J., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1184 · Cited by 544 · see citing works

Effect of Testosterone Treatment on Body Composition and Muscle Strength in Men Over 65 Years of Age

Snyder, P. J. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.8.2647 · Cited by 531 · see citing works

Achieving Weight and Activity Goals Among Diabetes Prevention Program Lifestyle Participants

The Diabetes Prevention Program Research Group (2004) · Obesity Research · doi:10.1038/oby.2004.179 · Cited by 529 · see citing works

A phase I/IItrial of MYO‐029 in adult subjects with muscular dystrophy

Wagner, K. R., Fleckenstein, J. L., Amato, A. A., Barohn, R. J., Bushby, K., Escolar, D. M., Flanigan, K. M., Pestronk, A., Tawil, R., Wolfe, G. I., et al. (2008) · Annals of Neurology · doi:10.1002/ana.21338 · Cited by 481 · see citing works

Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l’OSteoporose) Study

Rolland, Y., Lauwers-Cances, V., Cristini, C., van Kan, G. A., Janssen, I., Morley, J. E., & Vellas, B. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26950 · Cited by 465 · see citing works

The Response of Muscle Protein Anabolism to Combined Hyperaminoacidemia and Glucose-Induced Hyperinsulinemia Is Impaired in the Elderly¹

Volpi, E., Mittendorfer, B., Rasmussen, B. B., & Wolfe, R. R. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.12.7021 · Cited by 464 · see citing works

Physical frailty and body composition in obese elderly men and women

Villareal, D. T., Banks, M., Siener, C., Sinacore, D. R., & Klein, S. (2004) · Obesity Research · doi:10.1038/oby.2004.111 · Cited by 459 · see citing works

Growth Hormone and Sex Steroid Administration in Healthy Aged Women and Men: A Randomized Controlled Trial

Blackman, M. R. (2002) · JAMA · doi:10.1001/jama.288.18.2282 · Cited by 455 · see citing works

Sarcopenic Obesity: The Confluence of Two Epidemics

Roubenoff, R. (2004) · Obesity Research · doi:10.1038/oby.2004.107 · Cited by 453 · see citing works

Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction.

Volpi, E., Mittendorfer, B., Wolf, S., & Wolfe, R. R. (1999) · American Journal of Physiology · doi:10.1152/ajpendo.1999.277.3.e513 · Cited by 449 · see citing works

Lack of myostatin results in excessive muscle growth but impaired force generation

Amthor, H., Macharia, R., Navarrete, R., Schuelke, M., Brown, S., Otto, A., Voït, T., Francesco Muntoni, A., Vrbovà, G., Partridge, T. A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604893104 · Cited by 425 · see citing works

Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia

Rieu, I., Balage, M., Sornet, C., Giraudet, C., Pujos, E., Grizard, J., Mosoni, L., & Dardevet, D. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.110742 · Cited by 410 · see citing works

Systematic review: the safety and efficacy of growth hormone in the healthy elderly

Liu, H., Bravata, D. M., Olkin, I., Nayak, S., Roberts, B., Garber, A. M., & Hoffman, A. R. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-2-200701160-00005 · Cited by 370 · see citing works

Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?

Volpi, E., Campbell, W., Dwyer, J., Johnson, M., Jensen, G., Morley, J., & Wolfe, R. (2013) · The journals of gerontology. Series A, Biological sciences and medical sciences · doi:10.1093/gerona/gls229 · Cited by 361 · see citing works

Physical and Performance Measures for the Identification of Mild to Moderate Frailty

Brown, M., Sinacore, D. R., Binder, E. F., & Kohrt, W. M. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.6.m350 · Cited by 351 · see citing works

Prevalence of sarcopenia and sarcopenic obesity in the Korean population based on the fourth Korean National health and nutritional examination surveys

Kim, Y.-S., Lee, Y., Chung, Y.-S., Lee, D.-J., Joo, N.-S., Hong, D., Song, G. E., Kim, H.-J., Choi, Y. J., & Kim, K.-M. (2012) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls071 · Cited by 327 · see citing works

Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

Zhang, L., Rajan, V. R., Lin, E., Hu, Z., Han, H. Q., Zhou, X., Song, Y., Min, H., Wang, X., Du, J., et al. (2011) · The FASEB Journal · doi:10.1096/fj.10-176917 · Cited by 317 · see citing works

Effect of weight loss and exercise on frailty in obese older adults

Villareal, D. T., Banks, M., Sinacore, D. R., Siener, C., & Klein, S. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.8.860 · Cited by 302 · see citing works

Myostatin Knockout Drives Browning of White Adipose Tissue through Activating the AMPK-PGC1α-Fndc5 Pathway in Muscle

Shan, T., Liang, X., Bi, P., & Kuang, S. (2013) · The FASEB Journal · doi:10.1096/fj.12-225755 · Cited by 301 · see citing works

Intramuscular adipose tissue, sarcopenia, and mobility function in older individuals

Marcus, R. L., Addison, O., Dibble, L. E., Foreman, K. B., Morrell, G., & LaStayo, P. (2012) · Journal of Aging Research · doi:10.1155/2012/629637 · Cited by 296 · see citing works

Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting.

Yarasheski, K. E., Bhasin, S., Sinha‐Hikim, I., Pak-Loduca, J., & González-Cadavid, N. F. (2002) · PubMed · Cited by 293 · see citing works

Oxidative capacity of human muscle fiber types: effects of age and training status

Proctor, D. N., Sinning, W. E., Walro, J. M., Sieck, G. C., & Lemon, P. W. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.6.2033 · Cited by 283 · see citing works

Testosterone Deficiency in Men: Systematic Review and Standard Operating Procedures for Diagnosis and Treatment

Buvat, J., Maggi, M., Guay, A. T., & Torres, L. O. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02783.x · Cited by 281 · see citing works

Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin and a Reduced Efficiency of Akt Phosphorylation

Léger, B., Derave, W., Bock, K. D., Hespel, P., & Russell, A. P. (2008) · Rejuvenation Research · doi:10.1089/rej.2007.0588 · Cited by 274 · see citing works

Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons

Lambert, C. P., Wright, N. R., Finck, B. N., & Villareal, D. T. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00006.2008 · Cited by 249 · see citing works

The effect of obesity combined with low muscle strength on decline in mobility in older persons: results from the InCHIANTI Study

Stenholm, S., Alley, D., Bandinelli, S., Griswold, M. E., Koskinen, S., Rantanen, T., Guralnik, J. M., & Ferrucci, L. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.62 · Cited by 248 · see citing works

Aging does not impair the anabolic response to a protein-rich meal

Symons, T. B., Schutzler, S. E., Cocke, T. L., Chinkes, D. L., Wolfe, R. R., & Paddon-Jones, D. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.2.451 · Cited by 240 · see citing works

Exercise attenuates the weight-loss-induced reduction in muscle mass in frail obese older adults

FRIMEL, T. N., SINACORE, D. R., & VILLAREAL, D. T. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31816a85ce · Cited by 230 · see citing works

Aerobic Exercise Overcomes the Age-Related Insulin Resistance of Muscle Protein Metabolism by Improving Endothelial Function and Akt/Mammalian Target of Rapamycin Signaling

Fujita, S., Rasmussen, B. B., Cadenas, J. G., Drummond, M. J., Glynn, E. L., Sattler, F. R., & Volpi, E. (2007) · Diabetes · doi:10.2337/db06-1566 · Cited by 224 · see citing works

Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice

Zhang, C., McFarlane, C., Lokireddy, S., Masuda, S., Ge, X., Gluckman, P. D., Sharma, M., & Kambadur, R. (2012) · Diabetologia · doi:10.1007/s00125-011-2304-4 · Cited by 192 · see citing works

The Cardiometabolic Syndrome and Sarcopenic Obesity in Older Persons

Dominguez, L. J., & Barbagallo, M. (2007) · Journal of the CardioMetabolic Syndrome · doi:10.1111/j.1559-4564.2007.06673.x · Cited by 185 · see citing works

Weight loss in obese adults 65years and older: A review of the controversy

Waters, D. L., Ward, A. L., & Villareal, D. T. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.02.005 · Cited by 177 · see citing works

Effects of an Oral Growth Hormone Secretagogue in Older Adults

White, H. K., Petrie, C. D., Landschulz, W. H., MacLean, D. B., Taylor, A., Lyles, K. W., Wei, J. Y., Hoffman, A. R., Salvatori, R., Ettinger, M. P., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0632 · Cited by 171 · see citing works

Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exercise

Cuthbertson, D. J., Babraj, J., Smith, K., Wilkes, E., Fedele, M. J., Esser, K., & Rennie, M. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00415.2005 · Cited by 166 · see citing works

Loss-of-Function Mutation in Myostatin Reduces Tumor Necrosis Factor α Production and Protects Liver Against Obesity-Induced Insulin Resistance

Wilkes, J. J., Lloyd, D. J., & Gekakis, N. (2009) · Diabetes · doi:10.2337/db08-0245 · Cited by 156 · see citing works

Muscle mitochondrial changes with aging and exercise

Lanza, I. R., & Nair, K. S. (2008) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26717d · Cited by 152 · see citing works

Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance

Busquets, S., Toledo, M., Orpí, M., Massa, D., Porta, M. M., Capdevila, E., Padilla, N., Frailis, V., López-Soriano, F. J., Han, H. Q., et al. (2011) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-011-0049-z · Cited by 141 · see citing works

Effects of Testosterone and Progressive Resistance Exercise in Healthy, Highly Functioning Older Men With Low-Normal Testosterone Levels

Hildreth, K. L., Barry, D. W., Moreau, K. L., Vande Griend, J., Meacham, R. B., Nakamura, T., Wolfe, P., Kohrt, W. M., Ruscin, J. M., Kittelson, J., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-3695 · Cited by 140 · see citing works

Regular Multicomponent Exercise Increases Physical Fitness and Muscle Protein Anabolism in Frail, Obese, Older Adults

Villareal, D. T., Smith, G. I., Sinacore, D. R., Shah, K., & Mittendorfer, B. (2011) · Obesity · doi:10.1038/oby.2010.110 · Cited by 140 · see citing works

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults

Timmerman, K. L., Dhanani, S., Glynn, E. L., Fry, C. S., Drummond, M. J., Jennings, K., Rasmussen, B. B., & Volpi, E. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.020800 · Cited by 138 · see citing works

Hormone Replacement Therapy and Physical Function in Healthy Older Men. Time to Talk Hormones?

Giannoulis, M. G., Martin, F. C., Nair, K. S., Umpleby, A. M., & Sonksen, P. (2012) · Endocrine Reviews · doi:10.1210/er.2012-1002 · Cited by 132 · see citing works

Myostatin: more than just a regulator of muscle mass

Argilés, J. M., Orpí, M., Busquets, S., & López-Soriano, F. J. (2012) · Drug Discovery Today · doi:10.1016/j.drudis.2012.02.001 · Cited by 125 · see citing works

Frequent Sequence Variation in the Human Myostatin (GDF8) Gene as a Marker for Analysis of Muscle-Related Phenotypes

Ferrell, R. E., Conte, V., Lawrence, E., Roth, S. M., Hagberg, J. M., & Hurley, B. F. (1999) · Genomics · doi:10.1006/geno.1999.5984 · Cited by 125 · see citing works

DHEA enhances effects of weight training on muscle mass and strength in elderly women and men

Villareal, D. T., & Holloszy, J. O. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00100.2006 · Cited by 116 · see citing works

Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes

Leenders, M., & van Loon, L. J. C. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00443.x · Cited by 112 · see citing works

The Mediating Role of C‐Reactive Protein and Handgrip Strength Between Obesity and Walking Limitation

Stenholm, S., Rantanen, T., Heliövaara, M., & Koskinen, S. V. P. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01567.x · Cited by 108 · see citing works

Dehydroepiandrosterone Supplementation in Elderly Men: A Meta-Analysis Study of Placebo-Controlled Trials

Corona, G., Rastrelli, G., Giagulli, V. A., Sila, A., Sforza, A., Forti, G., Mannucci, E., & Maggi, M. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1358 · Cited by 105 · see citing works

Obesity Affects Nursing‐Care Facility Admission among Whites but Not Blacks

Zizza, C. A., Herring, A., Stevens, J., & Popkin, B. M. (2002) · Obesity Research · doi:10.1038/oby.2002.110 · Cited by 105 · see citing works

Effects of Androgen Therapy on Adipose Tissue and Metabolism in Older Men

Schroeder, E. T., Zheng, L., Ong, M. D., Martinez, C., Flores, C., Stewart, Y., Azen, C. G., & Sattler, F. R. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0784 · Cited by 93 · see citing works

Sarcopenic obesity: satellite cells in the aging muscle

Thornell, L.-E. (2011) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e3283412260 · Cited by 86 · see citing works

Metformin Increases the Novel Adipokine Cartonectin/CTRP3 in Women With Polycystic Ovary Syndrome

Tan, B. K., Chen, J., Hu, J., Amar, O., Mattu, H. S., Adya, R., Patel, V. C., Ramanjaneya, M., Lehnert, H., & Randeva, H. S. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2227 · Cited by 72 · see citing works

Increased Muscle Force Production and Bone Mineral Density in ActRIIB-Fc-Treated Mature Rodents

Chiu, C.-S., Peekhaus, N., Weber, H., Adamski, S., Murray, E. M., Zhang, H. Z., Zhao, J. Z., Ernst, R., Lineberger, J., Huang, L., et al. (2013) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glt030 · Cited by 68 · see citing works

Nutritionally essential amino acids and metabolic signaling in aging

Dillon, E. L. (2012) · Amino Acids · doi:10.1007/s00726-012-1438-0 · Cited by 67 · see citing works

The K153R Polymorphism in the Myostatin Gene and Muscle Power Phenotypes in Young, Non-Athletic Men

Santiago, C., Ruiz, J. R., Rodríguez‐Romo, G., Fiuza‐Luces, C., Yvert, T. P., González‐Freire, M., Gómez‐Gallego, F., Morán, M., & Lucía, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016323 · Cited by 64 · see citing works

The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism

Jackson, M. F., Luong, D., Vang, D. D., Garikipati, D. K., Stanton, J. B., Nelson, O. L., & Rodgers, B. D. (2012) · Journal of Endocrinology · doi:10.1530/joe-11-0455 · Cited by 64 · see citing works

Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO‐029

Krivickas, L. S., Walsh, R. J., & Amato, A. A. (2008) · Muscle & Nerve · doi:10.1002/mus.21200 · Cited by 62 · see citing works

Serum sex steroid hormones and frailty in older American men of the Third National Health and Nutrition Examination Survey (NHANES III)

Eichholzer, M., Barbir, A., Basaria, S. S., Dobs, A. S., Feinleib, M., Güallar, E., Menke, A., Nelson, W. G., Rifai, N., Platz, E. A., et al. (2012) · The Aging Male · doi:10.3109/13685538.2012.705366 · Cited by 62 · see citing works

Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia

Der‐Torossian, H., Wysong, A. S., Shadfar, S., Willis, M. S., McDunn, J. E., & Couch, M. E. (2013) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-012-0101-7 · Cited by 58 · see citing works

Resistance Training Leads to Clinically Meaningful Improvements in Control of Glycemia and Muscular Strength in Untrained Middle-aged Patients with type 2 Diabetes Mellitus

Hussain, M., Hameed, U. A., Manzar, M. D., Raza, S., & Shareef, M. Y. (2012) · North American Journal of Medical Sciences · doi:10.4103/1947-2714.99507 · Cited by 55 · see citing works

Associations of insulin‐like growth factor‐I and its binding proteins and testosterone with frailty in older men

Yeap, B. B., Paul Chubb, S. A., Lopez, D., Ho, K. K. Y., Hankey, G. J., & Flicker, L. (2013) · Clinical Endocrinology · doi:10.1111/cen.12052 · Cited by 53 · see citing works

Greater weight loss with increasing age in the weight loss maintenance trial

Svetkey, L. P., Clark, J. M., Funk, K., Corsino, L., Batch, B. C., Hollis, J. F., Appel, L. J., Brantley, P. J., Loria, C. M., Champagne, C. M., et al. (2014) · Obesity · doi:10.1002/oby.20506 · Cited by 53 · see citing works

Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated

McMahon, G. E., Morse, C. I., Burden, A., Winwood, K. L., & Onambélé-Pearson, G. L. (2013) · Muscle & Nerve · doi:10.1002/mus.23884 · Cited by 52 · see citing works

The Prevalence of Presarcopenia in Asian Indian Individuals With and Without Type 2 Diabetes

Anbalagan, V. P., Venkataraman, V., Pradeepa, R., Deepa, M., Anjana, R. M., & Mohan, V. (2013) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2013.0068 · Cited by 50 · see citing works

Metabolic Effects of a Growth Hormone-Releasing Factor in Obese Subjects with Reduced Growth Hormone Secretion: A Randomized Controlled Trial

Makimura, H., Feldpausch, M. N., Rope, A. M., Hemphill, L., Torriani, M., Lee, H., & Grinspoon, S. K. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2794 · Cited by 49 · see citing works

Lack of myostatin impairs mechanical performance and ATP cost of contraction in exercising mouse gastrocnemius muscle in vivo

Giannesini, B., Vilmen, C., Amthor, H., Bernard, M., & Bendahan, D. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00651.2012 · Cited by 47 · see citing works

Treatment with oxandrolone and the durability of effects in older men

Schroeder, E. T., Zheng, L., Yarasheski, K. E., Qian, D., Stewart, Y., Flores, C., Martinez, C., Terk, M. R., & Sattler, F. R. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00808.2003 · Cited by 40 · see citing works

Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis

Nakatani, M., Kokubo, M., Ohsawa, Y., Sunada, Y., & Tsuchida, K. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00430.2010 · Cited by 34 · see citing works

Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle

Siegel, M. P., Wilbur, T. K., Mathis, M., Shankland, E. G., Trieu, A., Harper, M., & Marcinek, D. J. (2012) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2012.08.002 · Cited by 34 · see citing works

The K153R variant in the myostatin gene and sarcopenia at the end of the human lifespan

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The beneficial effect of myostatin deficiency on maximal muscle force and power is attenuated with age

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