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Cited by 96Intestinal and Peritoneal AdhesionsSurgical Sutures and AdhesivesHernia repair and management

Biomaterials to Prevent Post-Operative Adhesion

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Park, Heekyung, Baek, Seungho, Kang, Hyun, Lee, Donghyun·2020·Materials
DOI 10.3390/ma13143056PMC PMC7412384
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Abstract

Surgery is performed to treat various diseases. During the process, the surgical site is healed through self-healing after surgery. Post-operative or tissue adhesion caused by unnecessary contact with the surgical site occurs during the normal healing process. In addition, it has been frequently found in patients who have undergone surgery, and severe adhesion can cause chronic pain and various complications. Therefore, anti-adhesion barriers have been developed using multiple biomaterials to prevent post-operative adhesion. Typically, anti-adhesion barriers are manufactured and sold in numerous forms, such as gels, solutions, and films, but there are no products that can completely prevent post-operative adhesion. These products are generally applied over the surgical site to physically block adhesion to other sites (organs). Many studies have recently been conducted to increase the anti-adhesion effects through various strategies. This article reviews recent research trends in anti-adhesion barriers.

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  • Electrospun anti-adhesion films can be made from biodegradable polymers and can incorporate drugs by techniques like coaxial (core-shell) electrospinning.

    “Electrospun anti-adhesion films can be made from biodegradable polymers and even incorporate drugs by techniques like coaxial (core–shell) electrospinning [12,271].”

    From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [12]

    Section 2.2.3 (page unavailable) says biodegradable PCL is made into electrospun anti-adhesion barriers and can be combined with a natural polymer in a core–sheath structure. Section 2.1.5 also describes drug-loaded anti-adhesion barriers made by electrospinning. The copy does not establish that drugs are incorporated specifically by coaxial or core–shell electrospinning. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

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Cited by

Sorted by citations

Authors
Park, H., Baek, S., Kang, H., & Lee, D.
Affiliations
  • Chung-Ang University (KR)
  • Chung-Ang University Healthcare System (KR)
Corresponding author
  • Kang, Hyun
  • Lee, Donghyun
ORCID
Venue
Materials
Publisher
MDPI AG
Published
2020-07-08
Volume
13
Issue
14
Pages
3056
ISSN
1996-1944 (ISSN-L)
DOI
10.3390/ma13143056
PMC
PMC7412384
OpenAlex
W3041573594
Cited by
96
References
6
Citations by year
2026: 6 · 2025: 15 · 2024: 32 · 2023: 13 · 2022: 18 · 2021: 11 · 2020: 1
FWCI
2.43
Type
journal article
Language
en
Open access
Licence
Locations
  • Materials (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Chung-Ang University (Chung-Ang University Research Scholarship Grants in 2018)
  • National Research Foundation of Korea (2018R1A2A2A05021467, NRF-2018R1D1A1B07048493)
Topics
  • Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
  • Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
  • Health Sciences › Medicine › Surgery › Hernia repair and management
Keywords
postoperative adhesions, anti-adhesion barrier, biomaterials, surgical wound healing, adhesion prevention

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