The DOI matches its Crossref record; 211 of the 211 references it cites were found in a registry or an index.
Alternative and Efficient Extraction Methods for Marine-Derived Compounds
Open accessAbstract
Marine ecosystems cover more than 70% of the globe's surface. These habitats are occupied by a great diversity of marine organisms that produce highly structural diverse metabolites as a defense mechanism. In the last decades, these metabolites have been extracted and isolated in order to test them in different bioassays and assess their potential to fight human diseases. Since traditional extraction techniques are both solvent- and time-consuming, this review emphasizes alternative extraction techniques, such as supercritical fluid extraction, pressurized solvent extraction, microwave-assisted extraction, ultrasound-assisted extraction, pulsed electric field-assisted extraction, enzyme-assisted extraction, and extraction with switchable solvents and ionic liquids, applied in the search for marine compounds. Only studies published in the 21st century are considered.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Those reviews showed the application of novel methods for extraction of bioactive compounds from both microalgae and macroalgae, but either of these reviews provided information only for one type of marine algae. However, microalgae were more mentioned than macroalgae because there are more available data in the literature about their bioactive compounds, as well as their potential for being imple”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [30]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Green Chemistry: Theory and Practice
Anastas, P. T., & Warner, J. C. (1998) · Medical Entomology and Zoology · Cited by 8,599
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,880
Springer Science+Business Media
Технология (2013) · Betascript Publishing eBooks · Cited by 3,087
Green Extraction of Natural Products: Concept and Principles
Chemat, F., Vian, M. A., & Cravotto, G. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms13078615 · Cited by 1,904
Haematococcus astaxanthin: applications for human health and nutrition
Guerin, M., Huntley, M. E., & Olaizola, M. (2003) · Trends in Biotechnology · doi:10.1016/s0167-7799(03)00078-7 · Cited by 1,495
Converti, A., Casazza, A. A., Ortiz, E. Y., Perego, P., & Del Borghi, M. (2009) · Chemical Engineering and Processing: Process Intensification · doi:10.1016/j.cep.2009.03.006 · Cited by 1,466
Reversible nonpolar-to-polar solvent
Jessop, P. G., Heldebrant, D. J., Li, X., Eckert, C. A., & Liotta, C. L. (2005) · Nature · doi:10.1038/4361102a · Cited by 973
Kaufmann, B., & Christen, P. (2002) · Phytochemical Analysis · doi:10.1002/pca.631 · Cited by 831
Inhibition of actin polymerization by latrunculin A
Coué, M., Brenner, S. L., Spector, I., & Korn, E. D. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)81513-2 · Cited by 824
Evolution and Diversity of Plant Cell Walls: From Algae to Flowering Plants
Popper, Z. A., Michel, G., Hervé, C., Domozych, D. S., Willats, W. G. T., Tuohy, M. G., Kloareg, B., & Stengel, D. B. (2011) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042110-103809 · Cited by 760
Research works printed but not linked: 2
- Hickey, A.J., and Ganderton, D. (2009). Pharmaceutical Process Engineering, CRC Press; Taylor and Francis Group. [2nd ed.].
- Rocha-Santos, T., and Duarte, A.C. (2014). Analysis of Marine Samples in Search of Bioactive Compounds, Elsevier.
Cited by
Sorted by citations
Carotenoid extraction methods: A review of recent developments
Saini, R. K., & Keum, Y.-S. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2017.07.099 · Cited by 857
Advances in Lipid Extraction Methods—A Review
Saini, R. K., Prasad, P., Shang, X., & Keum, Y.-S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413643 · Cited by 479
Marine Peptides: Bioactivities and Applications
Cheung, R. C. F., Ng, T. B., & Wong, J. H. (2015) · Marine Drugs · doi:10.3390/md13074006 · Cited by 398
Shannon, E., & Abu‐Ghannam, N. (2016) · Marine Drugs · doi:10.3390/md14040081 · Cited by 405
Chandra, R., Iqbal, H. M. N., Vishal, G., Lee, H., & Nagra, S. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.01.104 · Cited by 326
Metadata
- Authors
- Grosso, C., Valentão, P., Ferreres, F., & Andrade, P.
- Affiliations
- Universidade do Porto (PT)
- REQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, no. 228, Porto 4050-313, Portugal
- Centro de Edafología y Biología Aplicada del Segura (ES)
- Corresponding author
- Andrade, Paula
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2015-05-21
- Volume
- 13
- Issue
- 5
- Pages
- 3182-3230
- ISSN
- 1660-3397 (ISSN-L)
- PMC
- PMC4446625
- OpenAlex
- W1506732456
- Cited by
- 248
- References
- 211
- Citations by year
- 2026: 17 · 2025: 38 · 2024: 29 · 2023: 18 · 2022: 27 · 2021: 29 · 2020: 26 · 2019: 15 · 2018: 17 · 2017: 23 · 2016: 8 · 2015: 1
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Marine Drugs (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by-nc-sa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Strong
- European Commission (Pest-C/EQB/LA0006/2013, NORTE-07-0124 FEDER-000069)
- CYTED Ciencia y Tecnología para el Desarrollo (112RT0460)
- Fundação para a Ciência e a Tecnologia (COMPETE, NORTE-07-0124-FEDER-000069, PEst-C/EQB/LA0006/2013, IF/01332/2014)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Keywords
- marine natural products, extraction methods, supercritical fluid extraction, accelerated solvent extraction, microwave-assisted extraction, ultrasound-assisted extraction, enzymatic extraction, switchable solvents, ionic liquids, marine metabolites, bioactive compounds
- MeSH terms
- Animals, Biological Products, Humans, Marine Biology, Microwaves, Solvents, Chromatography, Supercritical Fluid, Aquatic Organisms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
