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Carotenoids from Marine Microalgae: A Valuable Natural Source for the Prevention of Chronic Diseases
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Epidemiological studies have shown a relation between antioxidants and the prevention of several chronic diseases. Microalgae are a potential novel source of bioactive molecules, including a wide range of different carotenoids that can be used as nutraceuticals, food supplements and novel food products. The objective of this review is (i) to update the research that has been carried out on the most known carotenoids produced by marine microalgae, including reporting on their high potentialities to produce other less known important compounds; (ii) to compile the work that has been done in order to establish some relationship between carotenoids and oxidative protection and treatment; (iii) to summarize the association of oxidative stress and the various reactive species including free radicals with several human diseases; and (iv) to provide evidence of the potential of carotenoids from marine microalgae to be used as therapeutics to treat or prevent these oxidative stress-related diseases.
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“Among these, astaxanthin from H. pluvialis is particularly potent, showing antioxidant activity thousands of times stronger than vitamin C and significantly outperforming β-carotene and vitamin E in neutralising singlet oxygen and lipid radicals [46].”
From Microalgae Bioactives for Functional Food Innovation and Health Promotion (2025) · cites this paper as [46]
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Metadata
- Authors
- Raposo, M., De Morais, A., & De Morais, R.
- Affiliations
- Universidade Católica Portuguesa (PT)
- CBQF—Centro de Biotecnologia e Química Fina—Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa/Porto, Rua Arquiteto Lobão Vital, Porto 4202-401, Portugal
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2015-08-14
- Volume
- 13
- Issue
- 8
- Pages
- 5128-5155
- ISSN
- 1660-3397 (ISSN-L)
- PMC
- PMC4557017
- OpenAlex
- W1495693701
- Cited by
- 228
- References
- 170
- Citations by year
- 2026: 12 · 2025: 26 · 2024: 23 · 2023: 25 · 2022: 29 · 2021: 31 · 2020: 23 · 2019: 26 · 2018: 18 · 2017: 11 · 2016: 4
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Marine Drugs (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by)
- Funders
- Fundação para a Ciência e a Tecnologia (OE/EQB/LA0016/2013, PEst-OE/EQB/LA0016/2013)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Keywords
- carotenoids, marine microalgae, antioxidants, oxidative stress, free radicals, reactive oxygen species, chronic disease prevention, nutraceuticals, dietary supplements, novel foods
- MeSH terms
- Animals, Antioxidants, Biological Products, Carotenoids, Chronic Disease, Humans, Oxidative Stress, Microalgae
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