Microalgae as sources of carotenoids

Guedes, Ana Catarina; Amaro, Helena M.; Malcata, Francisco Xavier

doi:10.3390/md9040625

Cited by 639Algal biology and biofuel productionSeaweed-derived Bioactive CompoundsPlant biochemistry and biosynthesis

Microalgae as sources of carotenoids

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Guedes, Ana Catarina, Amaro, Helena M., Malcata, Francisco Xavier·2011·Marine Drugs

DOI 10.3390/md9040625PMC PMC3124977

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Abstract

Marine microalgae constitute a natural source of a variety of drugs for pharmaceutical, food and cosmetic applications-which encompass carotenoids, among others. A growing body of experimental evidence has confirmed that these compounds can play important roles in prevention (and even treatment) of human diseases and health conditions, e.g., cancer, cardiovascular problems, atherosclerosis, rheumatoid arthritis, muscular dystrophy, cataracts and some neurological disorders. The underlying features that may account for such favorable biological activities are their intrinsic antioxidant, anti-inflammatory and antitumoral features. In this invited review, the most important issues regarding synthesis of carotenoids by microalgae are described and discussed-from both physiological and processing points of view. Current gaps of knowledge, as well as technological opportunities in the near future relating to this growing field of interest, are also put forward in a critical manner.

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Fucoxanthin has antioxidant, anti-obesity, and antidiabetic properties and can be used in cosmetics, pharmaceuticals, and nutraceuticals.
“For example, fucoxanthin has gained high attention due to its antioxidant, anti‐obesity, and antidiabetic properties, possible to be used in cosmetics, pharmaceuticals, and nutraceuticals (Guedes et al., 2011; Fung et al., 2013; Maeda et al., 2018).”
From Perspectives of fluorescence spectroscopy for online monitoring in microalgae industry (2022) · cites this paper as Guedes et al., 2011
The Cellular Location and Function section identifies fucoxanthin as a carotenoid produced by brown algae or diatoms. Practical Applications describes antioxidant properties and food and health uses for microalgal carotenoids generally, while the Introduction mentions pharmaceutical and cosmetic markets for microalgal products. Neither section attributes antioxidant, anti-obesity, or antidiabetic properties—or the listed uses—specifically to fucoxanthin. (LLM, conf=0.86)
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Primary carotenoids associated with growth are degraded under stress.
“Although studies have shown that nutrient deprivation can increase carotenoid production [66,67], it is also known that the primary carotenoids which are associated with growth are degraded under stress [68,69].”
From Response to nutrient variation on lipid productivity in green microalgae captured using second derivative FTIR and Raman spectroscopy (2022) · cites this paper as [69]

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[50]Guerin M Huntley ME Olaizola M Haematococcus astaxanthin: applications for human health and nutrition Trends Biotechnol 2003 21 210 216 12727382
[78]Fernández-Sevilla JM Acién-Fernández FG Pérez-Parra J Magán-Cañadas JJ Granado-Lorencio F Olmedilla B Large-scale production of high-content lutein extracts from S almeriensis Proceedings of 11th International Conference on Applied Phycology Galway, Ireland 21–26 June 2008
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Authors: Guedes, A. C., Amaro, H. M., & Malcata, F. X.
Affiliations: Universidade do Porto (PT)
Instituto Superior da Maia (PT)
Corresponding author: Malcata, Francisco Xavier
ORCID: Amaro, Helena M.
Malcata, Francisco Xavier
Venue: Marine Drugs
Publisher: MDPI AG
Published: 2011-04-20
Volume: 9
Issue: 4
Pages: 625-644
ISSN: 1660-3397 (ISSN-L)
DOI: 10.3390/md9040625
PMC: PMC3124977
OpenAlex: W2168964174
Cited by: 639
References: 89
Citations by year: 2026: 27 · 2025: 38 · 2024: 40 · 2023: 50 · 2022: 55 · 2021: 72 · 2020: 77 · 2019: 55 · 2018: 45 · 2017: 29 · 2016: 36 · 2015: 46 · 2014: 31 · 2013: 25 · 2012: 12
FWCI: 1.18
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (vor)
Locations: Marine Drugs (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: European Social Fund
Topics: Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
Keywords: microalgae, carotenoids, marine microalgae, carotenoid biosynthesis, antioxidant activity, anti-inflammatory activity, anticancer activity, disease prevention, pharmaceutical applications, food applications, cosmetic applications
MeSH terms: Animals, Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Carotenoids, Humans, Microalgae

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