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Lipid Production from Nannochloropsis
Open accessAbstract
Microalgae are sunlight-driven green cell factories for the production of potential bioactive products and biofuels. Nannochloropsis represents a genus of marine microalgae with high photosynthetic efficiency and can convert carbon dioxide to storage lipids mainly in the form of triacylglycerols and to the ω-3 long-chain polyunsaturated fatty acid eicosapentaenoic acid (EPA). Recently, Nannochloropsis has received ever-increasing interests of both research and public communities. This review aims to provide an overview of biology and biotechnological potential of Nannochloropsis, with the emphasis on lipid production. The path forward for the further exploration of Nannochloropsis for lipid production with respect to both challenges and opportunities is also discussed.
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“Genetic engineering plays a potentially pivotal role in advancing algal biofuels, aiming to tailor microalgal strains for an enhanced production of specific fuel precursors or even a direct synthesis of molecules like biodiesel, butanol, gasoline components, methane, ethanol, or jet fuel [165].”
From Biofuels, E-Fuels, and Waste-Derived Fuels: Advances, Challenges, and Future Directions (2025) · cites this paper as [165]
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“While specific quantitative comparisons of CO 2 -to-lipid conversion efficiencies between genetically modified strains (e.g., Nannochloropsis gaditana) and their wild-type counterparts require further consolidated data, research confirms the high lipid accumulation potential of species like N. gaditana (e.g., reaching 0.32 g/L lipid yield under specific enriched CO 2 lab conditions) and the focus”
From Biofuels, E-Fuels, and Waste-Derived Fuels: Advances, Challenges, and Future Directions (2025) · cites this paper as [165]
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“Simultaneously with an increase in lipid content, nitrogen starvation can decrease PUFA production, which is valuable for biodiesel production [1, 17–19].”
From Nitrogen and phosphorus stress as a tool to induce lipid production in microalgae (2023) · cites this paper as [17]
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Metadata
- Authors
- Ma, X.-N., Chen, T.-P., Yang, B., Liu, J., & Chen, F.
- Affiliations
- Institute for Food and Bioresource Engineering, College of Engineering, Peking University, Beijing 100871, China
- Peking University (CN)
- Corresponding author
- Liu, Jin
- Chen, Feng
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2016-03-25
- Volume
- 14
- Issue
- 4
- Pages
- 61
- ISSN
- 1660-3397 (ISSN-L)
- PMC
- PMC4849066
- OpenAlex
- W2309000102
- Cited by
- 394
- References
- 104
- Citations by year
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- FWCI
- 1.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Marine Drugs (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (31471717, 31571807)
- Peking University
- Ocean Public Welfare Scientific Research Project (201505032)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- Nannochloropsis, microalgae, lipid production, triglycerides, eicosapentaenoic acid, omega-3 fatty acids, biofuels, photosynthetic efficiency, CO2 conversion, microalgal biotechnology
- MeSH terms
- Animals, Biotechnology, Humans, Lipids, Triglycerides, Eicosapentaenoic Acid, Fatty Acids, Omega-3, Stramenopiles, Microalgae
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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