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Cited by 328

The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.

Marine Collagen as A Promising Biomaterial for Biomedical Applications

Open access
Lim, Ye-Seon, Ok, Ye-Jin, Hwang, Seon-Yeong, Kwak, Jong-Young, Yoon, Sik·2019·Marine Drugs

Abstract

This review focuses on the expanding role of marine collagen (MC)-based scaffolds for biomedical applications. A scaffold—a three-dimensional (3D) structure fabricated from biomaterials—is a key supporting element for cell attachment, growth, and maintenance in 3D cell culture and tissue engineering. The mechanical and biological properties of the scaffolds influence cell morphology, behavior, and function. MC, collagen derived from marine organisms, offers advantages over mammalian collagen due to its biocompatibility, biodegradability, easy extractability, water solubility, safety, low immunogenicity, and low production costs. In recent years, the use of MC as an increasingly valuable scaffold biomaterial has drawn considerable attention from biomedical researchers. The characteristics, isolation, physical, and biochemical properties of MC are discussed as an understanding of MC in optimizing the subsequent modification and the chemistries behind important tissue engineering applications. The latest technologies behind scaffold processing are assessed and the biomedical applications of MC and MC-based scaffolds, including tissue engineering and regeneration, wound dressing, drug delivery, and therapeutic approach for diseases, especially those associated with metabolic disturbances such as obesity and diabetes, are discussed. Despite all the challenges, MC holds great promise as a biomaterial for developing medical products and therapeutics.

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Metadata

Authors
Lim, Y.-S., Ok, Y.-J., Hwang, S.-Y., Kwak, J.-Y., & Yoon, S.
Venue
Marine Drugs
Publisher
MDPI AG
Published
2019-08-10
Volume
17
Issue
8
Pages
467
ISSN
1660-3397 (ISSN-L)
OpenAlex
W2967753885
Cited by
328
References
144
FWCI
8.28
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Marine Collagen as A Promising Biomaterial for Biomedical Applications. https://app.cochat.ai/papers/10.3390/md17080467
The paper
Lim, Y.-S., Ok, Y.-J., Hwang, S.-Y., Kwak, J.-Y., & Yoon, S. (2019). Marine Collagen as A Promising Biomaterial for Biomedical Applications. Marine Drugs. https://doi.org/10.3390/md17080467

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.