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Scaffolds in tissue engineering bone and cartilage

Hutmacher, Dietmar W.·2000·Biomaterials
DOI 10.1016/s0142-9612(00)00121-6
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Research works printed but not linked: 61

  1. Naughton, 1995, Emerging developments in tissue engineering and cell technology, Tissue Eng, 1(2), 211, 10.1089/ten.1995.1.211 · DOI
  2. Langer, 1993, Tissue engineering, Science, 260, 920, 10.1126/science.8493529 · DOI · Paper page
  3. Hollinger, 1992, Bone regeneration materials for the mandibular and craniofacial complex, Cells Mater, 2, 143
  4. Hutmacher, 1996, A review of material properties of biodegradable and bioresorbable polymers and devices for GTR and GBR applications, Int J Oral Maxillofac Implants, 11, 667
  5. Vert, 1992, Bioresorbability and biocompatibility of aliphatic polyesters, J Mater Sci, 3, 432
  6. Kronenthal, 1975, Biodegradable polymers in medicine and surgery, Polym Sci Technol, 8, 119
  7. Agrawal, 1997, Techniques to control pH in vicinity of biodegrading PLA–PGA implants, J Biomed Mater Res Appl Biomater, 38, 105, 10.1002/(SICI)1097-4636(199722)38:2<105::AID-JBM4>3.0.CO;2-U · doi:10.1002/(sici)1097-4636(199722)38:2<105::aid-jbm4>3.0.co;2-u
  8. Li, 1990, Structure–property relationships in the case of the degradation of massive aliphatic poly(α-hydroxy-acids) in aqueous media. Part 2: degradation of lactide–glycolide PLA37.5:GA25 and PLA75:GA poly(d,l-lactic acid), J Mater Sci: Mater Med, 1, 131, 10.1007/BF00700872 · DOI · Paper page
  9. Li, 1990, Structure–property relationships in the case of the degradation of massive aliphatic poly(α-hydroxy-acids) in aqueous media. Part 3: influence of the morphology of poly(l-lactic acid), J Mater Sci: Mater Med, 1, 198, 10.1007/BF00701077 · DOI · Paper page
  10. Bergsma, 1995, Late tissue response to poly(l-lactide) bone plates and screws, Biomaterials, 16, 25, 10.1016/0142-9612(95)91092-D · DOI · Paper page
  11. Bergsma, 1993, Foreign body reactions to resorbable poly(l-lactide) bone plates and screws used for the fixation of unstable zygomatic fractures, J Maxillofac Surg, 51, 666, 10.1016/S0278-2391(10)80267-8 · DOI · Paper page
  12. Böstmann, 1990, Foreign body reactions to fracture fixation implants of biodegradable synthetic polymers, J Bone Jt Surg, B72, 592, 10.1302/0301-620X.72B4.2199452 · DOI · Paper page
  13. Shikinami, 1998, Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly-l-lactide (PLLA): part I. Basic characteristics, Biomaterials, 20, 859, 10.1016/S0142-9612(98)00241-5 · DOI · Paper page
  14. Thompson, 1996, The effects of dynamic compressive loading on biodegradable implants of 50–50% polylactic acid–polyglycolic acid, Tissue Eng, 2, 61, 10.1089/ten.1996.2.61 · DOI
  15. Dunkelman, 1995, Cartilage production by rabbit articular chondrocytes on polyglycolic acid scaffolds in a closed bioreactor system, Biotechnol Bioeng, 46, 299, 10.1002/bit.260460402 · DOI
  16. Freed, 1994, Biodegradable polymer scaffolds for tissue engineering, Biotechnology, 12, 689, 10.1038/nbt0794-689 · DOI · Paper page
  17. Grande, 1997, Evaluation of matrix scaffolds for tissue engineering of cartilage grafts, J Biomed Mater Res, 34, 211, 10.1002/(SICI)1097-4636(199702)34:2<211::AID-JBM10>3.0.CO;2-L · DOI · Paper page
  18. Martin, 1998, In vitro differentiation of chick embryo bone marrow stromal cells into cartilaginous and bone-like tissues, J Orthop Res, 16, 181, 10.1002/jor.1100160205 · DOI
  19. Puelacher, 1996, Femoral shaft reconstruction using tissue engineered growth of bone, Int J Oral Maxillofac Surg, 25, 223, 10.1016/S0901-5027(96)80035-X · DOI
  20. Ma, 1999, Morphology and mechanical function of long-term in vitro engineered cartilage, J Biomed Mater Res, 44, 217, 10.1002/(SICI)1097-4636(199902)44:2<217::AID-JBM12>3.0.CO;2-6 · DOI
  21. Freed, 1998, Chondrogenesis in a cell–polymer-bioreactor system, Exp Cell Res, 240, 58, 10.1006/excr.1998.4010 · DOI · Paper page
  22. Reddi, 1987, Biological principles of bone induction, Orthopedic Clinics North America, 18, 207, 10.1016/S0030-5898(20)30384-9 · DOI · Paper page
  23. Brekke, 1996, A rationale delivery of osteoconductive proteins (a review), Tissue Eng, 2, 97, 10.1089/ten.1996.2.97 · doi:10.1089/ten.1996.2.97
  24. Chen CS, Milan Mrksich, Sui Huang, Whitesides GM, Ingber D. Geometric control of cell life and death. Science 1997;276:1425–8. · DOI · Paper page
  25. Ingber, 1997, Tensegrity: the architectural basis of cellular mechanotransduction, Ann Rev Physiol, 59, 575, 10.1146/annurev.physiol.59.1.575 · DOI · Paper page
  26. Freed, 1998, Chondrogenesis in a cell–polymer-bioreactor system, Exp Cell Res, 240, 58, 10.1006/excr.1998.4010 · DOI · Paper page
  27. Vander AJ, Shermann JH, Luciano DS. Human physiology. New York: McGraw-Hill, 1985. p. 341–66.
  28. Lu, 1996, The importance of new processing techniques in tissue engineering, MRS Bull, 11, 28, 10.1557/S088376940003181X · DOI · Paper page
  29. Mikos, 1994, Preparation and characterization of poly(l-lactic acid) foams, Polymer, 35, 1068, 10.1016/0032-3861(94)90953-9 · DOI · Paper page
  30. Mikos, 1993, Laminated three-dimensional biodegradable foams for use in tissue engineering, Biomaterials, 14, 323, 10.1016/0142-9612(93)90049-8 · DOI · Paper page
  31. Widmer, 1998, Manufacture of porous biodegradable polymer conduits by an extrusion process for guided tissue regeneration, Biomaterials, 19, 1945, 10.1016/S0142-9612(98)00099-4 · DOI · Paper page
  32. Tom, 1991, Particle formation with supercritical fluids—a review, J Aerosol Sci, 22, 555, 10.1016/0021-8502(91)90013-8 · DOI · Paper page
  33. Mooney, 1996, Novel approach to fabricate porous sponges of poly(d,l-lactic-co-glycolic acid) without the use of organic solvents, Biomaterials, 17, 1417, 10.1016/0142-9612(96)87284-X · DOI · Paper page
  34. Harris, 1998, Open pore biodegradable matrices formed with gas foaming, J Biomed Mater Res, 42, 396, 10.1002/(SICI)1097-4636(19981205)42:3<396::AID-JBM7>3.0.CO;2-E · DOI · Paper page
  35. Whang, 1995, A novel method to fabricate bioabsorbable scaffolds, Polymers, 36, 837, 10.1016/0032-3861(95)93115-3 · DOI · Paper page
  36. Whang, 1998, Ectopic bone formation via rhBMP-2 delivery from porous bioresorbable polymer scaffolds, J Biomed Mater Res, 42, 491, 10.1002/(SICI)1097-4636(19981215)42:4<491::AID-JBM3>3.0.CO;2-F · DOI · Paper page
  37. Whang, 1999, Engineering bone regeneration with bioabsorbable scaffolds with novel microarchitecture, Tissue Eng, 5, 35, 10.1089/ten.1999.5.35 · DOI · Paper page
  38. Nam, 1999, Porous biodegradable polymeric scaffolds prepared by thermally induced phase separation, J Biomed Mater Res, 47, 8, 10.1002/(SICI)1097-4636(199910)47:1<8::AID-JBM2>3.0.CO;2-L · DOI · Paper page
  39. Zhang, 1999, Poly(α-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology, J Biomed Mater Res, 44, 446, 10.1002/(SICI)1097-4636(19990315)44:4<446::AID-JBM11>3.0.CO;2-F · DOI · Paper page
  40. Schugens, 1996, Polylactide macroporous biodegradable implants for cell transplantation. 2. Preparation of polylactide foams by liquid–liquid phase separation, J Biomed Mater Res, 30, 449, 10.1002/(SICI)1097-4636(199604)30:4<449::AID-JBM3>3.0.CO;2-P · DOI · Paper page
  41. Lo, 1995, Fabrication of controlled release biodegradable foams by phase separation, Tissue Eng, 1, 15, 10.1089/ten.1995.1.15 · DOI · Paper page
  42. Rotter, 1998, Cartilage reconstruction in head and neck surgery: comparison of resorbable polymer scaffolds for tissue engineering of human septal cartilage, J Biomed Mater Res, 42, 347, 10.1002/(SICI)1097-4636(19981205)42:3<347::AID-JBM2>3.0.CO;2-J · DOI · Paper page
  43. Sittinger, 1996, Resorbable polyesters in cartilage engineering: affinity and biocompatibility of polymer fiber structures to chondrocytes, J Biomed Mater Res Appl Biomater, 33, 57, 10.1002/(SICI)1097-4636(199622)33:2<57::AID-JBM1>3.0.CO;2-K · doi:10.1002/(sici)1097-4636(199622)33:2<57::aid-jbm1>3.0.co;2-k
  44. Puelacher, 1996, Femoral shaft reconstruction using tissue engineered growth of bone, Int J Oral Maxillofac Surg, 25, 223, 10.1016/S0901-5027(96)80035-X · DOI
  45. Freed, 1998, Culture of organized cell communities, Adv Drug Deliver Rev, 33, 15, 10.1016/S0169-409X(98)00017-9 · DOI · Paper page
  46. Hutmacher DW, Burdet E, Schantz TJ, Robotic micro-assembly fabrication of three-dimensional bioresorbable scaffolds for tissue engineering, in press.
  47. Sachs, 1992, Three-dimensional printing, J Eng Industry, 114, 481, 10.1115/1.2900701 · DOI · Paper page
  48. Cima, 1991, Tissue engineering by cell transplantation using degradable polymer substrates, J Biomech Eng, 113, 143, 10.1115/1.2891228 · DOI · Paper page
  49. Park, 1998, Integration of surface modification and 3-D fabrication techniques to prepare patterned poly(l-lactide) substrates allowing regionally selective cell adhesion, J Biomater Sci Polym Ed, 9, 89, 10.1163/156856298X00451 · DOI · Paper page
  50. Wu, 1996, Solid free-form fabrication of drug delivery devices, J Contr Rel, 40, 77, 10.1016/0168-3659(95)00173-5 · DOI · Paper page
  51. Giordano, 1996, Mechanical properties of dense polylactic acid structures fabricated by three-dimensional printing, J Biomater Sci Polym Ed, 8, 63, 10.1163/156856297X00588 · DOI · Paper page
  52. Agarwala, 1996, Structural quality of parts processed by fused deposition, Rapid Prototyping J, 2, 4, 10.1108/13552549610732034 · DOI · Paper page
  53. Gray IV, 1998, Effects of processing conditions on short TCLP fiber reinforced FDM parts, Rapid Prototyping J, 1, 14, 10.1108/13552549810197514 · DOI · Paper page
  54. Buckwalter JA, Mankin, HJ, Articular cartilage. Part II: degeneration and osteoarthrosis, repair, regeneration, and transplantation. J Bone Jt Surg 1997;A79(4):612–32. · DOI · Paper page
  55. Newman, 1998, Articular cartilage repair, Amer J Sports Med, 26, 309, 10.1177/03635465980260022701 · DOI · Paper page
  56. Glowacki, 1998, Induced chondroblastic differentiation of human fibroblasts by three-dimensional culture with demineralized bone matrix, Mater Sci Eng, C6, 199, 10.1016/S0928-4931(98)00051-4 · doi:10.1016/s0928-4931(98)00051-4
  57. de Chalain, 1999, Bioengineering of elastic cartilage with aggregated porcine and human auricular chondrocytes and hydrogels containing alginate, collagen, and κ-elastin, J Biomed Mater Res, 44, 280, 10.1002/(SICI)1097-4636(19990305)44:3<280::AID-JBM6>3.0.CO;2-H · DOI
  58. Lee, 1998, Treatment of growth arrest by transfer of cultured chondrocytes into physeal defects, J Paediatric Orthoped, 18, 155, 10.1097/01241398-199803000-00005 · doi:10.1097/01241398-199803000-00005
  59. ten Koppel, 1998, Efficacy of perichondrium and a trabecular demineralized bone matrix for generating cartilage, Plast Reconstruct Surg, 102, 2012, 10.1097/00006534-199811000-00031 · doi:10.1097/00006534-199811000-00031
  60. Bruns, 1998, Autologous perichondral tissue for meniscal replacement, J Bone Jt Surg—British Volume, 80, 918, 10.1302/0301-620X.80B5.8023 · doi:10.1302/0301-620x.80b5.8023
  61. Hutmacher DW, Zein I, Teoh SH, Ng KW, Schantz JT, Leahy JC. Design and fabrication of a 3D scaffold for tissue engineering bone. In: Agrawal CM, Parr JE, Lin ST, editors. Synthetic bioabsorbable polymers for implants, STP 1396. American Society for Testing and Materials, West Conshohocken, PA, 2000. p. 52–67. · doi:10.1520/stp15307s

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Metadata

Authors
Hutmacher, D. W.
Venue
Biomaterials
Publisher
Elsevier BV
Published
2000-12
Volume
21
Issue
24
Pages
2529-2543
ISSN
0142-9612 (ISSN-L)
DOI
10.1016/s0142-9612(00)00121-6
OpenAlex
W2124195334
Cited by
4,994
References
2
FWCI
45.81
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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Hutmacher, D. W. (2000). Scaffolds in tissue engineering bone and cartilage. Biomaterials. https://doi.org/10.1016/s0142-9612(00)00121-6

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