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N-Acetylglucosamine: Production and Applications

Open access
Chen, Jeen-Kuan, Shen, Chia-Rui, Liu, Chao-Lin·2010·Marine Drugs

Abstract

N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin, the second most abundant carbohydrate after cellulose. In addition to serving as a component of this homogeneous polysaccharide, GlcNAc is also a basic component of hyaluronic acid and keratin sulfate on the cell surface. In this review, we discuss the industrial production of GlcNAc, using chitin as a substrate, by chemical, enzymatic and biotransformation methods. Also, newly developed methods to obtain GlcNAc using glucose as a substrate in genetically modified microorganisms are introduced. Moreover, GlcNAc has generated interest not only as an underutilized resource but also as a new functional material with high potential in various fields. Here we also take a closer look at the current applications of GlcNAc, and several new and cutting edge approaches in this fascinating area are thoroughly discussed.

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Metadata

Authors
Chen, J.-K., Shen, C.-R., & Liu, C.-L.
Venue
Marine Drugs
Publisher
MDPI AG
Published
2010-09-15
Volume
8
Issue
9
Pages
2493-2516
ISSN
1660-3397 (ISSN-L)
OpenAlex
W2013647096
Cited by
386
References
0
FWCI
5.05
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: N-Acetylglucosamine: Production and Applications. https://app.cochat.ai/papers/10.3390/md8092493
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Chen, J.-K., Shen, C.-R., & Liu, C.-L. (2010). N-Acetylglucosamine: Production and Applications. Marine Drugs. https://doi.org/10.3390/md8092493

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