Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease

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Memantine prodrug as a new agent for Alzheimer’s Disease

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7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer’s Disease Treatment — Synthesis, Biological Evaluation and Molecular Modeling Studies

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Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140—A Multitarget Compound for Alzheimer’s Disease

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A Spectrum of Topics for 2019: Advances in Neuroinflammation, Oxidative Stress, Obesity, Diabetes Mellitus, Cardiovascular Disease, Autism, Exosomes, and Central Nervous System Diseases.

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Basic information about memantine and its treatment of Alzheimer's disease and other clinical applications

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Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

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Memantine: Updating a rare success story in pro-cognitive therapeutics

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Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases

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Alzheimer's disease: The role of proteins in formation, mechanisms, and new therapeutic approaches

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Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis

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Therapeutic Options in Alzheimer’s Disease: From Classic Acetylcholinesterase Inhibitors to Multi-Target Drugs with Pleiotropic Activity

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Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors

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Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease

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Analysis of skeletal diversity of multi-target directed ligands (MTDLs) targeting Alzheimer's disease

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Memantine protects the cultured rat hippocampal neurons treated by NMDA and amyloid β1–42

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Memantine-Derived Schiff Bases as Transdermal Prodrug Candidates

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Donepezil and Memantine Derivatives for Dual-Function and Prodrug Applications in Alzheimer’s Disease

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Prodrug Therapies for Infectious and Neurodegenerative Diseases

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Computational Identification and Functional Analysis of Potentially Pathogenic nsSNPs in the NLRP3 Gene Linked to Alzheimer’s Disease

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Attenuation of Vanadium-Induced Neurotoxicity in Rat Hippocampal Slices (In Vitro) and Mice (In Vivo) by ZA-II-05, a Novel NMDA-Receptor Antagonist

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Alzheimer’s disease: a jigsaw puzzle comprised of different types of programmed cell death pieces

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Hybridization of Aminoadamantanes with Cinnamic Acid Analogues and Elucidation of Their Antioxidant Profile

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Combined Effects of Donepezil and Memantine on Behavioral and Psychological Symptoms, Cognitive Function, and Daily Living Abilities in Patients With Alzheimer’s Disease

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The Bidirectional Mechanism of Uric Acid Levels on Alzheimer’s Disease: A Narrative Review

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Available Treatment Modules for Brain Disorders

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Molecular insights into P2X signalling cascades in acute kidney injury

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Calcium Modulating Effect of Polycyclic Cages: A Suitable Therapeutic Approach Against Excitotoxic-induced Neurodegeneration

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Safety and efficacy of rivastigmine and memantine combined for treatment of patients with Alzheimer’s disease: a retrospective study

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Unfavorable effects of memantine on the skeletal system in female rats

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In Silico and In Vivo Evaluation of a New Derivative from Memantine and Sinapic Acid (N-Sinapoyl-memantine) as a Candidate for the Management of Alzheimer’s Disease

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Role of GSK-3 Inhibition in Alzheimer’s Disease Therapy

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Exploring prodrug approaches for Alzheimer’s treatment: an overview

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Linking structure to activity in Ni(II) complexes with {NiN₂O₄} geometry via spectroscopic analysis

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Memantine: A look ahead. Insights into structure, syntheses, receptor binding mechanisms, drug hybrids and formulations, and potential repurposing

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From pathology to precision therapy: Contemporary and emerging strategies in Alzheimer's disease treatment

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Unlocking Neurodegeneration: Scaffold-Derived Blockers of MAO-B and AChE inspired by Bryophyllum pinnatum: A Structural ExplorationPreprint

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New directions of research in the pharmacotherapy of Alzheimer’s disease

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Polypharmacology in Clinical Applications: Neurological Polypharmacology

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Protective effects of resveratrol on nerves in rats with Alzheimer?s disease

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A technology-aided program to support positive occupation in people with advanced Alzheimer’s disease: A pilot study

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Design, Synthesis, and Neurotrophic Effect of Arg-Glu-Arg-Met-Ser-(3,5)-Dimethyladamantan-1-Amine In Vitro Evaluations as a Potential NMDAR Antagonist

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Modern approaches to pharmacotherapy of Alzheimer's disease

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Alzheimer's disease - a review of medicinal substances and their derivatives

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Prodrugs for neurodegenerative diseases

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Efficacy of combination therapy with Donepezil and Memantine in Alzheimer and mixed dementia: A comparative study

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Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights

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Radiofrequency electromagnetic fields in Alzheimer’s therapy: emerging evidence and future prospects

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Rational design of B, Ge, Mg, and Si-decorated Al₁₂N₁₂ nanocages from composite density functional theory insight: toward efficient memantine nanocarrier design for Alzheimer’s therapy

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Memantine and its analogs: Potential applications in cancer therapy

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Effects of adjunctive memantine on executive function and global cognition in bipolar disorder (BD): A randomized, double-blind, placebo-controlled clinical trial

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BindingDB Entry 50014711: Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease.

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BindingDB Entry 50013796: Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.

BindingDB (2022) · UC San Diego · doi:10.7270/q2pc365g

Recent Advances in Medicinal Chemistry of Memantine Against Alzheimer's Disease

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Multi-target Design Strategies in the Context of Alzheimer’s Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces

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NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy

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Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer’s Disease

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