Equol: A Bacterial Metabolite from The Daidzein Isoflavone and Its Presumed Beneficial Health Effects

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Glucagon-like peptide 1 in health and disease

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Equol: History, Chemistry, and Formation

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Therapeutic Potential and Mechanisms of Novel Simple O-Substituted Isoflavones against Cerebral Ischemia Reperfusion

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Understanding and harnessing triple-negative breast cancer-related microbiota in oncology

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Soy‐derived isoflavones as chemo‐preventive agents targeting multiple signalling pathways for cancer prevention and therapy

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Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids

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The role of nutrition and gut microbiome in childhood brain development and behavior

Jiang, Y., & Li, Y. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1590172 · Cited by 35

Urinary Equol and Equol‐Predicting Microbial Species Are Favorably Associated With Cardiometabolic Risk Markers in Chinese Adults

Liang, S., Zhang, H., Mo, Y., Li, Y., Zhang, X., Cao, H., Xie, S., Wang, D., Lv, Y., Wu, Y., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.034126 · Cited by 24

Polyphenols and Microbiota Modulation: Insights from Swine and Other Animal Models for Human Therapeutic Strategies

Anghel, A. C., Țăranu, I., Orțan, A., Spinu, S. M., Cudalbeanu, M. D., Rosu, P. M., & Babeanu, N. E. (2024) · Molecules · doi:10.3390/molecules29246026 · Cited by 24

Pomegranate: A Comprehensive Review of Functional Components, Health Benefits, Processing, Food Applications, and Food Safety

Zhang, M., Tang, X., Mao, B., Zhang, Q., Zhao, J., Chen, W., & Cui, S. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c05428 · Cited by 28

Microbiome based precision medicine through integrated multiomics and machine learning

Kumar, A., Xu, C., & Dakal, T. C. (2025) · Microbiological Research · doi:10.1016/j.micres.2025.128384 · Cited by 24

Metabolism of Soy Isoflavones by Intestinal Bacteria: Genome Analysis of an Adlercreutzia equolifaciens Strain That Does Not Produce Equol

Vázquez, L., Flórez, A. B., Redruello, B., & Mayo, B. (2020) · Biomolecules · doi:10.3390/biom10060950 · Cited by 23

Synergistic Activity of Equol and Meropenem against Carbapenem-Resistant Escherichia coli

Kim, H.-R., & Eom, Y.-B. (2021) · Antibiotics · doi:10.3390/antibiotics10020161 · Cited by 19

Heterologous expression of equol biosynthesis genes from Adlercreutzia equolifaciens

Vázquez, L., Flórez, A. B., Rodríguez, J., & Mayo, B. (2021) · FEMS Microbiology Letters · doi:10.1093/femsle/fnab082 · Cited by 22

Integrated multiomic wastewater-based epidemiology can elucidate population-level dietary behaviour and inform public health nutrition assessments

Bowes, D. A., Driver, E. M., Savic, S., Cheng, Q., Whisner, C. M., Krajmalnik‐Brown, R., & Halden, R. U. (2023) · Nature Food · doi:10.1038/s43016-023-00717-w · Cited by 22

Application of recombinant lactic acid bacteria and bifidobacteria able to enrich soy beverage in dihydrodaidzein and dihydrogenistein

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Biocompatible natural deep eutectic solvent-based extraction and cellulolytic enzyme-mediated transformation of Pueraria mirifica isoflavones: a sustainable approach for increasing health-bioactive constituents

Makkliang, F., Siriwarin, B., Yusakul, G., Phaisan, S., Sakdamas, A., Chuphol, N., Putalun, W., & Sakamoto, S. (2021) · Bioresources and Bioprocessing · doi:10.1186/s40643-021-00428-9 · Cited by 20

Trifolium pratense ethanolic extract alters the gut microbiota composition and regulates serum lipid profile in the ovariectomized rats

Quah, Y., Park, N., Lee, E., Lee, K., Chan, J. Y.-L., Ali, M. S., Jang, S.-H., Kim, M., Lee, S., & Park, S. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03486-w · Cited by 20

S-Equol enhances osteoblastic bone formation and prevents bone loss through OPG/RANKL via the PI3K/Akt pathway in streptozotocin-induced diabetic rats

Xu, Z., Xu, J., Li, S., Cui, H., Zhang, G., Ni, X., & Wang, J. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.986192 · Cited by 20

Dietary Impacts on Gestational Diabetes: Connection between Gut Microbiome and Epigenetic Mechanisms

Bankole, T., Winn, H. N., & Li, Y. (2022) · Nutrients · doi:10.3390/nu14245269 · Cited by 22

Phytoestrogens, novel dietary supplements for breast cancer

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Roles of Phytoestrogen in the Pathophysiology of Intracranial Aneurysm

Yokosuka, K., Rutledge, C., Kamio, Y., Kuwabara, A., Sato, H., Rahmani, R., Purcell, J., Eguchi, S., Baranoski, J. F., Margaryan, T., et al. (2021) · Stroke · doi:10.1161/strokeaha.120.032042 · Cited by 19

Advances in equol production: Sustainable strategies for unlocking soy isoflavone benefits

Ortíz, C., & Manta, B. (2024) · Results in Chemistry · doi:10.1016/j.rechem.2023.101288 · Cited by 19

Enrichment of milk antioxidant activity by dietary supplementation of red clover isoflavone in cows and its improvement on mice intestinal health

Zhang, X., Xiong, Z., Zhang, S., Li, K., Bu, Y., Zheng, N., Zhao, S., & Wang, J. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.138764 · Cited by 20

Naturally occurring hormones in foods and potential health effects

Palacios, O. M., Cortes, H. N., Jenks, B. H., & Maki, K. C. (2020) · Toxicology Research and Application · doi:10.1177/2397847320936281 · Cited by 20

Isolation and identification of a human intestinal bacterium capable of daidzein conversion

Guo, Y., Zhao, L., Fang, X., Zhong, Q., Liang, H., Liang, W., & Wang, L. (2021) · FEMS Microbiology Letters · doi:10.1093/femsle/fnab046 · Cited by 19

Polyphenol-Derived Microbiota Metabolites and Cardiovascular Health: A Concise Review of Human Studies

Pinaffi‐Langley, A. C. D. C., Tarantini, S., Hord, N. G., & Yabluchanskiy, A. (2024) · Antioxidants · doi:10.3390/antiox13121552 · Cited by 24

Occurrence of Polyphenols, Isoflavonoids, and Their Metabolites in Milk Samples from Different Cow Feeding Regimens

Rocchetti, G., Ghilardelli, F., Mosconi, M., Masoero, F., & Gallo, A. (2022) · Dairy · doi:10.3390/dairy3020024 · Cited by 22

High Titer of (S)-Equol Synthesis from Daidzein in Escherichia coli

Deng, H., Gao, S., Zhang, W., Zhang, T., Li, N., & Zhou, J. (2022) · ACS Synthetic Biology · doi:10.1021/acssynbio.2c00378 · Cited by 18

Gut Microbiota-Assisted Synthesis, Cellular Interactions and Synergistic Perspectives of Equol as a Potent Anticancer Isoflavone

Tuli, H. S., Kumar, A., Sak, K., Aggarwal, D., Gupta, D., Kaur, G., Vashishth, K., Dhama, K., Kaur, J., Saini, A. K., et al. (2022) · Pharmaceuticals · doi:10.3390/ph15111418 · Cited by 18

Phytochemicals and Vitamin D for a Healthy Life and Prevention of Diseases

Santa, K., Watanabe, K., Kumazawa, Y., & Nagaoka, I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512167 · Cited by 21

Synthesis of Daidzein and Thiophene Containing Benzoxazine Resin and Its Thermoset and Carbon Material

Yao, Z., Lu, Y., Song, J., & Zhang, K. (2023) · Molecules · doi:10.3390/molecules28135077 · Cited by 17

The role of processing on phenolic bioaccessibility and antioxidant capacity of apple derivatives

Alongi, M., Lanza, U., Gorassini, A., Verardo, G., Comuzzi, C., Anese, M., Manzocco, L., & Nicoli, M. C. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.141402 · Cited by 18

A comprehensive metabolome profiling of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica to explore the medicinal potential of Triphala

Hegde, S. N., Lavanya Devi, K., Choudhary, M., Menon, N. S., & Singh, G. (2024) · Scientific Reports · doi:10.1038/s41598-024-80544-6 · Cited by 17

Therapeutic Efficacy of Soy-Derived Bioactives: A Systematic Review of Nutritional Potency, Bioactive Therapeutics, and Clinical Biomarker Modulation

Fatima, Z., Itrat, N., Israr, B., & Ahmad, A. M. R. (2025) · Foods · doi:10.3390/foods14193447 · Cited by 18

Microbial production and transformation of polyphenols

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Gut metabolite S‐equol ameliorates hyperexcitability in entorhinal cortex neurons following Theiler murine encephalomyelitis virus‐induced acute seizures

Gallucci, A., Patel, D. C., Thai, K., Trinh, J., Gude, R., Shukla, D., & Campbell, S. L. (2021) · Epilepsia · doi:10.1111/epi.16979 · Cited by 17

Prospective association of dietary soy and fibre intake with puberty timing: a cohort study among Chinese children

Xiong, J., Xu, Y., Liu, X., Wang, X., Shan, S., Crabbe, M. J. C., Zhao, L., He, F., & Cheng, G. (2022) · BMC Medicine · doi:10.1186/s12916-022-02320-5 · Cited by 17

Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury

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Genistein Inhibits Clostridioides difficile Infection via Estrogen Receptors and Lysine-Deficient Protein Kinase 1

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Fermented soy beverages as vehicle of probiotic lactobacilli strains and source of bioactive isoflavones: A potential double functional effect

de la Bastida, A. R., Peirotén, Á., Langa, S., Rodrı́guez, E., Curiel, J. A., Arqués, J. L., & Landete, J. M. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e14991 · Cited by 16

Association between equol production and metabolic syndrome in Japanese women in their 50s-60s

Takahashi, A., Kokubun, M., Anzai, Y., Kogre, A., Ogata, T., Imaizumi, H., Fujita, M., Hayashi, M., Abe, K., & Ohira, H. (2022) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000002052 · Cited by 15

The Role of Choline, Soy Isoflavones, and Probiotics as Adjuvant Treatments in the Prevention and Management of NAFLD in Postmenopausal Women

DiStefano, J. K. (2023) · Nutrients · doi:10.3390/nu15122670 · Cited by 15

A critical appraisal of geroprotective activities of flavonoids in terms of their bio-accessibility and polypharmacology

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Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey

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The role of gut microbiota metabolites in the regeneration and protection of nervous tissue: a narrative review

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Graphene oxide decorated daidzein as an oral drug to ameliorate the oxidative stress and glucocorticoid-induced osteoporosis in vivo zebrafish model

Priya, P. S., Vaishnavi, S., Pavithra, V., Pachaiappan, R., Kumar, S. B., Almutairi, B. O., Arokiyaraj, S., & Arockiaraj, J. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104278 · Cited by 14

Phenolic compounds in dietary target the regulation of gut microbiota: Role in health and disease

Zhang, Q., Xu, Y., Bukvički, D., Peng, Y., Li, F., Zhang, Q., Yan, J., Lin, S., Liu, S., & Qin, W. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105107 · Cited by 16

An improved whole‐cell biotransformation system for (S)‐equol production

Li, B., Xiao, M., Dong, X., & Huang, Z. (2022) · Food Science & Nutrition · doi:10.1002/fsn3.2840 · Cited by 14

In Silico Molecular Docking and ADMET Analysis for Drug Development of Phytoestrogens Compound with Its Evaluation of Neurodegenerative Diseases

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Associations between Intake of Dietary Flavonoids and 10-Year Incidence of Age-Related Hearing Loss

Gopinath, B., McMahon, C. M., Lewis, J. R., Bondonno, N. P., Bondonno, C. P., Burlutsky, G., Hodgson, J. M., & Mitchell, P. L. R. (2020) · Nutrients · doi:10.3390/nu12113297 · Cited by 14

Effects of soy isoflavones on growth performance, antioxidant capacity, non-specific immunity and lipid metabolism of juvenile Chinese mitten crab, Eriocheir sinensis

He, L., Wang, H., Li, E., Huang, Q., Wang, X., Qiao, F., Qin, C., Qin, J., & Chen, L. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.740470 · Cited by 13

Enhanced anti-aging effect of nicotinamide mononucleotide encapsulated with reactive oxygen species responsive nanoparticles with liver and mitochondrial targeting abilities

Sun, S., Zhang, L., Fei, S., & Tan, M. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.153372 · Cited by 13

Preparation of a Lactobacillus rhamnosus ATCC 7469 microencapsulated-lactulose synbiotic and its effect on equol production

Wang, X., Ma, Y., Liu, Y., Zhang, J., Jiang, W., Fang, X., & Wang, L. (2024) · Food & Function · doi:10.1039/d4fo02690j · Cited by 13

Association of equol producing status with aortic calcification in middle-aged Japanese men: The ERA JUMP study

Zhang, X., Fujiyoshi, A., Ahuja, V., Vishnu, A., Barinas‐Mitchell, E., Kadota, A., Miura, K., Edmundowicz, D., Ueshima, H., & Sekikawa, A. M. (2022) · International Journal of Cardiology · doi:10.1016/j.ijcard.2022.01.065 · Cited by 13

Development of the first fermented soy beverages enriched in equol and 5-hydroxy-equol

Langa, S., de la Bastida, A. R., Peirotén, Á., Curiel, J. A., & Landete, J. M. (2022) · LWT · doi:10.1016/j.lwt.2022.113899 · Cited by 13

Urinary phytoestrogens and the risk of uterine leiomyomata in US women

Yang, F., & Chen, Y. (2023) · BMC Women s Health · doi:10.1186/s12905-023-02381-5 · Cited by 13

Soy-Derived Equol Induces Antioxidant Activity in Zebrafish in an Nrf2-Independent Manner

Watanabe, A., Muraki, K., Tamaoki, J., & Kobayashi, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23095243 · Cited by 12

The gut-derived metabolites as mediators of the effect of healthy nutrition on the brain

Leyrolle, Q., Prado-Perez, L., & Layé, S. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1155533 · Cited by 13

Equol, a metabolite of gut microbiota, attenuates liver steatosis via the SIRT1/HNF4α pathway in NAFLD mice

Luo, Z., Yang, L., He, J., Han, Y., Rong, X., Luo, D., & Guo, J. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105640 · Cited by 12

The dietary intervention of synbiotic preparation promotes the bioconversion of soy isoflavones to equol and its metabolic mechanism

Wang, X., Ma, Y., Wu, X., Chen, B., Fang, X., Zhong, Q., Liao, Z., Wang, J., & Wang, L. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105784 · Cited by 12

Characterization and stabilization of GluLm and its application to deglycosylate dietary flavonoids and lignans

Curiel, J. A., de la Bastida, A. R., Langa, S., Peirotén, Á., & Landete, J. M. (2024) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12956-9 · Cited by 12

Menopause Hot Flashes and Molecular Mechanisms Modulated by Food-Derived Nutrients

Forma, E., Urbańska, K., & Bryś, M. (2024) · Nutrients · doi:10.3390/nu16050655 · Cited by 12

Equol promotes the in vitro maturation of porcine oocytes by activating the NRF2/KEAP1 signaling pathway

Xiao, S. J., Peng, K., Chen, R., Liu, X., Zhou, B., He, R., Yan, Y., Wan, R., Yin, Y., Lu, S., et al. (2024) · Theriogenology · doi:10.1016/j.theriogenology.2024.11.015 · Cited by 12

The Influence of the Probiotics, Ketogenic Diets, and Gut Microbiota on Epilepsy and Epileptic Models: A Comprehensive Review

Shirzadi, P., Farokh, P., Meinagh, S. O., Izadi-Jorshari, G., Hajikarimloo, B., Mohammadi, G., Parvardeh, S., & Nassiri‐Asl, M. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04993-4 · Cited by 12

Daidzein promotes milk synthesis and proliferation of mammary epithelial cells via the estrogen receptor α-dependent NFκB1 activation

Yu, M., Qi, H., & Gao, X. (2020) · Animal Biotechnology · doi:10.1080/10495398.2020.1763376 · Cited by 12

Production of Bovine Equol-Enriched Milk: A Review

Křížová, L., Křešťáková, V., Dadáková, K., & Kašparovský, T. (2021) · Animals · doi:10.3390/ani11030735 · Cited by 12

The Modulatory Effect of Cyclocarya paliurus Flavonoids on Intestinal Microbiota and Hypothalamus Clock Genes in a Circadian Rhythm Disorder Mouse Model

Sun, Y., Ho, C., Liu, Y., Zhan, S., Wu, Z., Zheng, X., & Zhang, X. (2022) · Nutrients · doi:10.3390/nu14112308 · Cited by 12

Cross-sectional association of equol producing status with aortic calcification in Japanese men aged 40–79 years

Zhang, X., Fujiyoshi, A., Kadota, A., Kondo, K., Torii, S., Okami, Y., Hisamatsu, T., Yano, Y., Barinas‐Mitchell, E., Magnani, J. W., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-24659-8 · Cited by 12

BRD9 Inhibition by Natural Polyphenols Targets DNA Damage/Repair and Apoptosis in Human Colon Cancer Cells

Kapoor, S., Damiani, E., Wang, S., Dharmanand, R., Tripathi, C., Perez, J. E. T., Dashwood, W. M., Rajendran, P., & Dashwood, R. H. (2022) · Nutrients · doi:10.3390/nu14204317 · Cited by 12

The phytoestrogenic potential of flavonoid glycosides from Selaginella moellendorffii via ERα-dependent signaling pathway

Yuan, S., Li, Z., Huang, W., Chen, K., & Li, J. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116174 · Cited by 11

Effects of different strains fermentation on the sensory and nutritional properties of soy‐based yogurt

Xu, X., Yan, Y., Xu, J., Yuan, Z., Li, J., Wang, S., Yang, L., Liu, J., Liu, H., & Zhu, D. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12941 · Cited by 11

Gut microbial change after administration of Lacticaseibacillus paracasei AO356 is associated with anti-obesity in a mouse model

Song, E., Lee, E., Kim, Y. I., Shin, D., Eom, J.-E., Shin, H. S., Lee, S., & Nam, Y. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1224636 · Cited by 12

Role of the intestinal microbiota and diet in the onset and progression of colorectal and breast cancers and the interconnection between both types of tumours

Ruiz-Saavedra, S., Zapico, A., González, S., Salazar, N., & Reyes‐Gavilán, C. G. D. L. (2023) · Microbiome Research Reports · doi:10.20517/mrr.2023.36 · Cited by 12

Potential of using an engineered indole lactic acid producing Escherichia coli Nissle 1917 in a murine model of colitis

Dimopoulou, C. D., Guerra, P. R., Mortensen, M. S., Kristensen, K. A., Pedersen, M., Bahl, M. I., Sommer, M., Licht, T. R., & Laursen, M. F. (2024) · Scientific Reports · doi:10.1038/s41598-024-68412-9 · Cited by 11

Anaerobic phloroglucinol degradation by Clostridium scatologenes

Zhou, Y., Wei, Y., Jiang, L., Jiao, X., & Zhang, Y. (2023) · mBio · doi:10.1128/mbio.01099-23 · Cited by 14

Fish as the lesser-known counterpart to mammalian models to explore the biofunctionality of polyphenols

Abdelhafiz, Y. A., Gora, A. H., Rehman, S., Chowdhury, S., Park, Y., Bisa, S., Verlhac-Trichet, V., Fernandes, J. M. O., Sørensen, M., & Kiron, V. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105654 · Cited by 11

Phenolic Compounds and Derivatives in Ruminant Meat and Milk: A Systematic Review

Ahsin, M., Matarneh, S. K., Thornton, K. J., Kronberg, S. L., Amir, M., & van Vliet, S. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c06118 · Cited by 10

Sex-Specific Diet–Microbiota Interactions in Ageing: Implications for Healthy Longevity

Hernández-Acosta, J., Tovar, A. R., & Torres, N. (2025) · Nutrients · doi:10.3390/nu17243833 · Cited by 10

Synergistic Effects of Polyphenols and Gut Microbiota–Derived Metabolites on Inflammation and Metabolic Syndrome: A Review

Rakhra, G., Malhotra, R., Prasad, P., Sahu, J. K., Rakhra, G., Khan, T. U., Khan, M. U., & Rastogi, S. (2026) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70360 · Cited by 11

Gut Microbial Metabotypes Shape Polyphenol Bioactivity: Toward Precision Nutrition Strategies for Human Health

Perrone, P., & D’Angelo, S. (2026) · Nutrients · doi:10.3390/nu18142396 · Cited by 12

Equol-based epoxy resin as an ideal substitute for the diglycidyl ether of bisphenol A (DGEBA)

Xue, K., Wu, Q., Zhang, P., Song, Z., Liu, H., Chai, M., Guo, X., Li, S., & Liu, L. (2024) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2024.110856 · Cited by 10

A Narrative Review: Immunometabolic Interactions of Host–Gut Microbiota and Botanical Active Ingredients in Gastrointestinal Cancers

Li, S., Feng, W., Wu, J., Cui, H., Wang, Y., Liang, T., An, J., Chen, W., Guo, Z., & Lei, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25169096 · Cited by 10

Effect of Fermented Soy Beverage on Equol Production by Fecal Microbiota

de la Bastida, A. R., Langa, S., Curiel, J. A., Peirotén, Á., & Landete, J. M. (2024) · Foods · doi:10.3390/foods13172758 · Cited by 10

Analysis of the biotransformation mechanism of soy isoflavones via equol-producing HMA mice model

Wu, X., Zhao, L., Ma, Y., Liang, W., Fang, X., Liao, Z., Zhong, Q., Wang, J., & Wang, L. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105274 · Cited by 10

Physiological relevance of food antioxidants

Cömert, E. D., & Gökmen, V. (2020) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2020.03.002 · Cited by 11

The Oxidation of Equol by Tyrosinase Produces a Unique Di-ortho-Quinone: Possible Implications for Melanocyte Toxicity

Tanaka, H., Ito, S., Ojika, M., Nishimaki‐Mogami, T., Kondo, K., & Wakamatsu, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179145 · Cited by 10

Strategies to achieve significant physiological concentrations of bioactive phytoestrogens in plasma

Langa, S., & Landete, J. M. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1971946 · Cited by 10

Health Effects of Drinking Water Produced from Deep Sea Water: A Randomized Double-Blind Controlled Trial

Takeuchi, H., Yoshikane, Y., Takenaka, H., Kimura, A., Islam, J. M., Matsuda, R., Okamoto, A., Hashimoto, Y., Yano, R., Yamaguchi, K., et al. (2022) · Nutrients · doi:10.3390/nu14030581 · Cited by 9

Systems biology approaches to identify potential targets and inhibitors of the intestinal microbiota to treat depression

Teng, F., Lü, Z., Gao, F., Liang, J., Li, J., Tian, X., Wang, X., Guan, H., & Wang, J. (2023) · Scientific Reports · doi:10.1038/s41598-023-38444-8 · Cited by 9

Isoflavones Effects on Vascular and Endothelial Outcomes: How Is the Gut Microbiota Involved?

Laudani, S., Godos, J., Romano, G. L., Gozzo, L., Domenico, F. D., Azpíroz, I. D., Diaz, R. M., Giampieri, F., Quiles, J. L., Battino, M. A., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17020236 · Cited by 10

Maternal probiotic exposure enhances CD8 T cell protective neonatal immunity and modulates offspring metabolome to control influenza virus infection

Valentin, C., Rodrigues, P. B., Verce, M., Delbauve, S., Palombara, L. L., Demaret, F., Allard, J., Salmon, I. J., Cani, P. D., Köhler, A., et al. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2442526 · Cited by 10

Gut microbiota associated with equol production in school-age children

Wada, K., Suda, W., Ueno, T., Masuoka, H., Yamakawa, M., Nakashima, Y., Sugino, M., Mori, T., Uchiyama, S., Sumoto, Y., et al. (2025) · European Journal of Nutrition · doi:10.1007/s00394-025-03625-w · Cited by 10

Pharmacotherapeutic potential of daidzein: insights into mechanisms and clinical relevance

Chinchu Praisthy, L. J., Kushwah, R., Dubey, S., Kumar, V., & Jain, S. (2025) · Inflammopharmacology · doi:10.1007/s10787-025-01891-y · Cited by 9

Gut microbial modulation of 3-hydroxyanthranilic acid and dopaminergic signalling influences attention in obesity

Castells‐Nobau, A., Fumagalli, A., del Castillo-Izquierdo, Á., Rosell-Díaz, M., de la Vega-Correa, L., Samulenaite, S., Motger‐Albertí, A., Arnoriaga‐Rodríguez, M., Garre‐Olmo, J., Puig, J., et al. (2025) · Gut · doi:10.1136/gutjnl-2025-336391 · Cited by 9

Equol: A Microbiota Metabolite Able to Alleviate the Negative Effects of Zearalenone during In Vitro Culture of Ovine Preantral Follicles

Silva, T. E. S., de Brito, D. C. C., de Sá, N. A. R., da Silva, R. F., Ferreira, A. C. A., da Silva, J. Y. G., Guedes, M. I. F., Rodrigues, A. P. R., dos Santos, R. R., & Figueiredo, J. R. (2019) · Toxins · doi:10.3390/toxins11110652 · Cited by 9

Isoflavones of Soy: Chemistry and Health Benefits

Mir, R. H., Sabreen, S., Mohi-ud-din, R., Wani, T. U., Jaleel, A., Jan, R., Banday, N., Maqbool, M., Mohi-ud-din, I., Mir, B. I., et al. (2022) · Springer eBooks · doi:10.1007/978-981-16-4880-9_13 · Cited by 10

Anti-bacterial and Anti-biofilm Effects of Equol on Yersinia enterocolitica

Kim, H., Han, M.-S., & Eom, Y. (2022) · Indian Journal of Microbiology · doi:10.1007/s12088-022-01020-1 · Cited by 9

Feeding Soy Protein Concentrates with Low and High Isoflavones Alters 9 and 18 Weeks Serum Isoflavones and Inflammatory Protein Levels in Lean and Obese Zucker Rats

Li, W., Twaddle, N. C., Spray, B. J., Nounamo, B., Monzavi‐Karbassi, B., & Hakkak, R. (2023) · Journal of Medicinal Food · doi:10.1089/jmf.2022.0100 · Cited by 11

The Metabolites and Mechanism Analysis of Genistin against Hyperlipidemia via the UHPLC-Q-Exactive Orbitrap Mass Spectrometer and Metabolomics

Li, Z., Dong, W., Li, Y., Liu, X., Wang, H., Dai, L., Zhang, J., & Wang, S. (2023) · Molecules · doi:10.3390/molecules28052242 · Cited by 9

Anti-Menopausal Effect of Soybean Germ Extract and Lactobacillus gasseri in the Ovariectomized Rat Model

Lee, S., Lim, T.-J., Yun, E. J., Kim, K. H., & Lim, S. (2023) · Nutrients · doi:10.3390/nu15204485 · Cited by 11

The effects of esketamine on the intestinal microenvironment and intestinal microbiota in mice

Zhang, Y., Ma, W., Lin, H., Gu, X., & Xie, H. (2023) · Human & Experimental Toxicology · doi:10.1177/09603271231211894 · Cited by 9

Metabolism of dietary soy isoflavones to equol by human intestinal microflora – implications for health

Yuan, J., Wang, J., & Liu, X. (2007) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200600262 · Cited by 325

Bioconversion of Isoflavones into Bioactive Equol: State of the Art

Lopes, D. B., de Ávila, A. R. A., de Queirós, L. D., Macedo, J. A., & Macêdo, G. A. (2016) · Recent Patents on Food Nutrition & Agriculture · doi:10.2174/2212798408666160620090519 · Cited by 8

Advances in equol production: Sustainable strategies for unlocking soy isoflavone benefits

Ortíz, C., & Manta, B. (2024) · Results in Chemistry · doi:10.1016/j.rechem.2023.101288 · Cited by 19

Is equol production beneficial to health?

Magee, P. J. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s0029665110003940 · Cited by 49

Transformation of Daidzein to Equol and Its Bioactivity

Uehara, M., Ishimi, Y., Katsumata, S.-I., & Suzuki, K. (2008) · ACS symposium series · doi:10.1021/bk-2008-0993.ch008 · Cited by 2