The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Pollen Food Allergy Syndrome in Allergic March
Abstract
The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS at 13 years old (at 5 years, Cry j 1: adjusted odds ratio aOR, 2.74; 95% confidence interval CI, 1.53–4.91; Fel d 1: aOR, 2.61; 95% CI, 1.31–5.19; at 9 years, Cry j 1: adjusted odds ratio aOR, 4.28; 95% confidence interval CI, 1.98–9.25; Fel d 1: aOR, 2.40; 95% CI, 1.33–4.32). In particular, sensitization to Bet v 1 at ages 5 and 9 years was associated with a strong risk of PFAS at the age of 13 years (at 5 years: aOR, 10.6; 95% CI, 2.64–42.5; at 9 years: aOR, 9.1; 95% CI, 4.71–17.6). PFAS risk by age 13 years was increased by any allergic symptom at 5 or 9 years, a combination of wheezing, eczema, and rhinitis, and Bet v 1 sensitization. Our findings suggest that PFAS may be associated with allergic march.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“as the development of PFAS often follows prolonged sensitization to pollen allergens over time [61].”
From Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges (2024) · cites this paper as [61]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The atopic march and atopic multimorbidity: many trajectories, many pathways
Paller, A. S., Spergel, J. M., Mina-Osorio, P., & Irvine, A. D. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.11.006 · Cited by 464 · cited 1×
“Several studies have suggested that the mechanisms underlying the development of atopic comorbidities could involve an impaired cutaneous barrier, resulting in cutaneous sensitization, thereby leading to a systemic Th2-dominant immune response to cutaneous inflammation [9,11].”
BackgroundHill, D. A., Grundmeier, R. W., Ram, G., & Spergel, J. M. (2016) · BMC Pediatrics · doi:10.1186/s12887-016-0673-z · Cited by 243
Influence of antibiotic use in early childhood on asthma and allergic diseases at age 5
Yamamoto-Hanada, K., Yang, L., Narita, M., Saito, H., & Ohya, Y. (2017) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2017.05.013 · Cited by 129
Self-citationEpidemiological study of oral allergy syndrome in birch pollen dispersal-free regions
Osawa, Y., Ito, Y., Takahashi, N., Sugimoto, C., Kohno, Y., Mori, S., Morikawa, T., Kato, Y., Okamoto, M., Kanno, M., et al. (2020) · Allergology International · doi:10.1016/j.alit.2019.09.008 · Cited by 31
Research works printed but not linked: 24
- Amlot, 1987, Oral allergy syndrome (OAS): Symptoms of IgE-mediated hypersensitivity to foods, Clin. Allergy, 17, 33, 10.1111/j.1365-2222.1987.tb02317.x · DOI
- Lessof, 1996, Pollen-food allergy syndrome, J. Allergy Clin. Immunol., 98, 239, 10.1016/S0091-6749(96)70252-X · DOI
- Carlson, 2019, Pollen food allergy syndrome (PFAS): A review of current available literature, Ann. Allergy Asthma Immunol., 123, 359, 10.1016/j.anai.2019.07.022 · DOI · Paper page
- Matricardi, 2016, EAACI molecular allergology User’s guide, Pediatr. Allergy Immunol., 27, 1, 10.1111/pai.12563 · DOI · Paper page
- Zelniker, 2011, Birch pollen-related food allergy: Clinical aspects and role of allergen-specific IgE and IgG4 antibodies, J. Allergy Clin. Immunol., 127, 616, 10.1016/j.jaci.2010.10.027 · DOI
- Ciprandi, 2016, Birch allergy and oral allergy syndrome: The practical relevance of serum immunoglobulin E to Bet v 1, Allergy Asthma Proc., 37, 43, 10.2500/aap.2016.37.3914 · DOI · Paper page
- Kiguchi, T., Yamamoto-Hanada, K., Saito-Abe, M., Sato, M., Irahara, M., Ogita, H., Miyagi, Y., Inuzuka, Y., Toyokuni, K., and Nishimura, K. (2021). Pollen-food allergy syndrome and component sensitization in adolescents: A Japanese population-based study. PLoS ONE, 16. · DOI · Paper page
- Hill, 2018, The atopic march: Critical evidence and clinical relevance, Ann. Allergy Asthma Immunol., 120, 131, 10.1016/j.anai.2017.10.037 · DOI
- Leung, 2014, Deciphering the complexities of atopic dermatitis: Shifting paradigms in treatment approaches, J. Allergy Clin. Immunol., 134, 769, 10.1016/j.jaci.2014.08.008 · DOI
- Tran, 2018, Predicting the atopic march: Results from the Canadian Healthy Infant Longitudinal Development study, J. Allergy Clin. Immunol., 141, 601, 10.1016/j.jaci.2017.08.024 · DOI
- Belgrave, D.C., Granell, R., Simpson, A., Guiver, J., Bishop, C., Buchan, I., Henderson, A.J., and Custovic, A. (2014). Developmental profiles of eczema, wheeze, and rhinitis: Two population-based birth cohort studies. PLoS Med., 11. · DOI
- Borres, 2020, IgE responses to multiple allergen components among school-aged children in a general population birth cohort in Tokyo, World Allergy Organ. J., 13, 100105, 10.1016/j.waojou.2020.100105 · DOI
- Yang, 2018, Phenotypes of childhood wheeze in Japanese children: A group-based trajectory analysis, Pediatr Allergy Immunol., 29, 606, 10.1111/pai.12917 · DOI
- Koseki, 2019, Effect of filaggrin loss-of-function mutations on atopic dermatitis in young age: A longitudinal birth cohort study, J. Hum. Genet., 64, 911, 10.1038/s10038-019-0628-y · DOI
- Irahara, M., Yamamoto-Hanada, K., Yang, L., Saito-Abe, M., Sato, M., Inuzuka, Y., Toyokuni, K., Nishimura, K., Ishikawa, F., and Miyaji, Y. (2020). Impact of swimming school attendance in 3-year-old children with wheeze and rhinitis at age 5 years: A prospective birth cohort study in Tokyo. PLoS ONE, 15. · DOI
- Hamilton, 2020, Advances in IgE testing for diagnosis of allergic disease, J. Allergy Clin. Immunol. Pract., 8, 2495, 10.1016/j.jaip.2020.07.021 · DOI
- Martínez-Aranguren, R., Lizaso, M.T., Goikoetxea, M.J., García, B.E., Cabrera-Freitag, P., Trellez, O., and Sanz, M.L. (2014). Is the determination of specific IgE against components using ISAC 112 a reproducible technique?. PLoS ONE, 9. · DOI
- Hauser, 2010, Panallergens and their impact on the allergic patient, Allergy Asthma Clin. Immunol., 6, 1, 10.1186/1710-1492-6-1 · DOI · Paper page
- Asher, 1995, International study of asthma and allergies in childhood (ISAAC): Rationale and methods, Eur. Respir. J., 8, 483, 10.1183/09031936.95.08030483 · DOI · Paper page
- Weiland, 2004, Phase II of the international study of asthma and allergies in childhood (ISAAC II): Rationale and methods, Eur. Respir. J., 24, 406, 10.1183/09031936.04.00090303 · DOI · Paper page
- Ellwood, 2005, The international study of asthma and allergies in childhood (ISAAC): Phase three rationale and methods, Int. J. Tuberc. Lung Dis., 9, 10
- Marrs, 2019, Dog ownership at three months of age is associated with protection against food allergy, Allergy, 74, 2212, 10.1111/all.13868 · DOI
- Gao, 2020, Effect of exposure to cats and dogs on the risk of asthma and allergic rhinitis: A systematic review and meta-analysis, Am. J. Rhinol. Allergy, 34, 703, 10.1177/1945892420932487 · DOI
- Pawankar, 2014, Allergic diseases and asthma: A global public health concern and a call to action, World Allergy Organ. J., 7, 12, 10.1186/1939-4551-7-12 · DOI
Cited by
Sorted by citations
Kato, Y., Morikawa, T., & Fujieda, S. (2025) · Allergology International · doi:10.1016/j.alit.2024.08.007 · Cited by 45
Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges
Haidar, L., Bănărescu, C. F., Uța, C., Moldovan, S. I., Zimbru, E.-L., Zimbru, R.-I., Ciurariu, E., Georgescu, M., & Panaitescu, C. (2024) · Applied Sciences · doi:10.3390/app15010066 · Cited by 21
Metadata
- Authors
- Yasudo, H., Yamamoto-Hanada, K., Yang, L., Saito-Abe, M., Sato, M., Miyaji, Y., Shimada, M., Hirai, S., Toyokuni, K., Ishikawa, F., Inuzuka, Y., Kabashima, S., Fukuie, T., & Ohya, Y.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2022-06-27
- Volume
- 14
- Issue
- 13
- Pages
- 2658
- ISSN
- 2072-6643
- PMC
- PMC9268136
- Cited by
- 15
- References
- 4
- Language
- en
- Funders
- National Center for Child Health and Development (26-1)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
