Cited by 123Adipokines, Inflammation, and Metabolic DiseasesRetinoids in leukemia and cellular processesAdipose Tissue and Metabolism

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Vitamin A Metabolism and Adipose Tissue Biology

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Frey, Simone K., Vogel, Silke·2011·Nutrients

DOI 10.3390/nu3010027PMC PMC3257733

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Abstract

In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models point to a relationship between vitamin A metabolism and the development of adiposity. Similarly, in vitro studies provide new molecular mechanisms for the function of different forms of vitamin A and retinol- or retinoic acid-binding proteins in adipose tissue.

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Authors: Frey, S. K., & Vogel, S.
Affiliations: Columbia University (US)
Corresponding author: Vogel, Silke
ORCID: Vogel, Silke
Venue: Nutrients
Publisher: MDPI AG
Published: 2011-01-06
Volume: 3
Issue: 1
Pages: 27-39
ISSN: 2072-6643 (ISSN-L)
DOI: 10.3390/nu3010027
PMC: PMC3257733
OpenAlex: W2149014180
Cited by: 123
References: 68
Citations by year: 2026: 5 · 2025: 5 · 2024: 7 · 2023: 9 · 2022: 14 · 2021: 10 · 2020: 11 · 2019: 6 · 2018: 3 · 2017: 7 · 2016: 10 · 2015: 9 · 2014: 13 · 2013: 8 · 2012: 6
FWCI: 1.01
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (vor)
Locations: Nutrients (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Atmosphere (cc-by)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinoids in leukemia and cellular processes
Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Keywords: vitamin A metabolism, adipose tissue, obesity, type 2 diabetes, retinoic acid, retinol, retinol-binding protein, adipose tissue biology, adiposity
MeSH terms: Adipose Tissue, Animals, Tretinoin, Vitamin A, Receptors, Retinoic Acid, Mice, Knockout, Adiposity, Mice, Rats, Retinol-Binding Proteins, Cellular

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