The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Systematic Review of Anthocyanins and Markers of Cardiovascular Disease
Open accessAbstract
Anthocyanins are dietary flavonoids commonly consumed in the diet, which have been suggested to have a preventative effect on cardiovascular disease (CVD) development among epidemiological studies. We systematically reviewed randomized controlled trials (RCTs) testing the effects of purified anthocyanins and anthocyanin-rich extracts on markers of CVD (triglycerides, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and blood pressure) in both healthy and diseased populations. Eligible studies included RCTs of adults published in English. We searched PubMed, Web of Science Core Collection, and BIOSIS Previews for relevant articles from inception until 1 July 2014. Twelve RCTs representing 10 studies were included in this review. Supplementation with anthocyanins significantly improved LDL cholesterol among diseased individuals or those with elevated biomarkers. Supplementation did not significantly affect other markers of CVD in either healthy individuals or those with elevated markers. No adverse effects of anthocyanins were reported across studies at levels up to 640 mg/day. Limitations of trials in the qualitative analyses include short trial duration and large variability in the dose administered within the trials. Longer-duration trials assessing dose response are needed to adequately determine whether an effect of supplementation exists.
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Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · BMJ · doi:10.1136/bmj.b2700 · Cited by 17,648
The Physical Activity Guidelines for Americans
Piercy, K. L., Troiano, R. P., Ballard, R. M., Carlson, S. A., Fulton, J. E., Galuska, D. A., George, S. M., & Olson, R. D. (2018) · JAMA · doi:10.1001/jama.2018.14854 · Cited by 9,755
Berries: emerging impact on cardiovascular health
Basu, A., Rhone, M., & Lyons, T. J. (2010) · Nutrition Reviews · doi:10.1111/j.1753-4887.2010.00273.x · Cited by 462 · cited 3×
“It is possible that anthocyanins may have the ability to modulate low-grade inflammation, as consumption of anthocyanin-rich foods such as berries have been suggested to affect many inflammatory markers of CVD in vivo [4].”
BackgroundInfluentialFavorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol
Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., & Jula, A. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.2.323 · Cited by 445
Qin, Y., Xia, M., Ma, J., Hao, Y., Liu, J., Mou, H., Cao, L., & Ling, W. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27814 · Cited by 443
Basu, A., Wilkinson, M., Penugonda, K., Simmons, B., Betts, N. M., & Lyons, T. J. (2009) · Nutrition Journal · doi:10.1186/1475-2891-8-43 · Cited by 164
Effect of cranberry extracts on lipid profiles in subjects with type 2 diabetes
Lee, I. T., Chan, Y. C., Lin, C. W., Lee, W. J., & Sheu, W. H. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02588.x · Cited by 150
Cited by
Polyphenols: A concise overview on the chemistry, occurrence, and human health
Durazzo, A., Lucarini, M., Souto, E. B., Cicala, C., Caiazzo, E., Izzo, A. A., Novellino, E., & Santini, A. (2019) · Phytotherapy Research · doi:10.1002/ptr.6419 · Cited by 802
Wallace, T. C., Bailey, R. L., Blumberg, J. B., Burton-Freeman, B., Chen, C.-Y. O., Crowe-White, K. M., Drewnowski, A., Hooshmand, S., Johnson, E., Lewis, R., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1632258 · Cited by 638
Self-citationAnthocyanin food colorant and its application in pH-responsive color change indicator films
Roy, S., & Rhim, J.-W. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1776211 · Cited by 592
Chemistry, Pharmacology and Health Benefits of Anthocyanins
Smeriglio, A., Barreca, D., Bellocco, E., & Trombetta, D. (2016) · Phytotherapy Research · doi:10.1002/ptr.5642 · Cited by 447
Cicero, A. F. G., Colletti, A., Bajraktari, G., Descamps, O., Djuric, D. M., Ezhov, M., Fras, Z., Katsiki, N., Langlois, M., Latkovskis, G., et al. (2017) · Archives of Medical Science · doi:10.5114/aoms.2017.69326 · Cited by 281
Metadata
- Authors
- Wallace, T., Slavin, M., & Frankenfeld, C.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2016-01-09
- Volume
- 8
- Issue
- 1
- Pages
- 32
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2229218795
- Cited by
- 197
- References
- 7
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
