The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery
Open accessAbstract
Transdermal delivery systems have gained much interest in recent years owing to their advantages compared to conventional oral and parenteral delivery systems. They are noninvasive and self-administered delivery systems that can improve patient compliance and provide a controlled release of the therapeutic agents. The greatest challenge of transdermal delivery systems is the barrier function of the skin’s outermost layer. Molecules with molecular weights greater than 500 Da and ionized compounds generally do not pass through the skin. Therefore, only a limited number of drugs are capable of being administered by this route. Encapsulating the drugs in transfersomes are one of the potential approaches to overcome this problem. They have a bilayered structure that facilitates the encapsulation of lipophilic and hydrophilic, as well as amphiphilic, drug with higher permeation efficiencies compared to conventional liposomes. Transfersomes are elastic in nature, which can deform and squeeze themselves as an intact vesicle through narrow pores that are significantly smaller than its size. This review aims to describe the concept of transfersomes, the mechanism of action, different methods of preparation and characterization and factors affecting the properties of transfersomes, along with their recent applications in the transdermal administration of drugs.
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Clinical translation of nanomedicines: Challenges, opportunities, and keys
Younis, M. A., Tawfeek, H. M., Abdellatif, A. A. H., Abdel-Aleem, J. A., & Harashima, H. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114083 · Cited by 462
Advancements in nanoparticle-based treatment approaches for skin cancer therapy
Zeng, L., Gowda, B. H. J., Ahmed, M. G., Abourehab, M. A. S., Chen, Z.-S., Zhang, C., Li, J., & Kesharwani, P. (2023) · Molecular Cancer · doi:10.1186/s12943-022-01708-4 · Cited by 365
Recent Formulation Advances of Mangiferin
Barakat, S., Nasr, M., Ahmed, R. F., Badawy, S., & Mortada, N. (2022) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-022-00297-z · Cited by 28
Food Peptides for the Nutricosmetic Industry
Dini, I., & Mancusi, A. (2023) · Antioxidants · doi:10.3390/antiox12040788 · Cited by 28
Opatha, S. A. T., Chutoprapat, R., Khankaew, P., Titapiwatanakun, V., Ruksiriwanich, W., & Boonpisuttinant, K. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.123738 · Cited by 25
Self-citation
Metadata
- Authors
- Opatha, S. A. T., Titapiwatanakun, V., & Chutoprapat, R.
- Venue
- Pharmaceutics
- Publisher
- MDPI AG
- Published
- 2020-09-09
- Volume
- 12
- Issue
- 9
- Pages
- 855
- ISSN
- 1999-4923 (ISSN-L)
- OpenAlex
- W3083987393
- Cited by
- 537
- References
- 83
- FWCI
- 19.45
- Type
- journal article
- Language
- en
- Open access
- gold
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- Opatha, S. A. T., Titapiwatanakun, V., & Chutoprapat, R. (2020). Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery. Pharmaceutics. https://doi.org/10.3390/pharmaceutics12090855
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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