Cited by 407Plant Stress Responses and ToleranceRedox biology and oxidative stressPlant-Microbe Interactions and Immunity

Regulation of Reactive Oxygen Species during Salt Stress in Plants and Their Crosstalk with Other Signaling Molecules—Current Perspectives and Future Directions

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Kesawat, Mahipal Singh, Satheesh, Neela, Kherawat, Bhagwat Singh, Kumar, Ajay, Kim, Hyun-Uk, Chung, Sang-Min, Kumar, Manu·2023·Plants

Abstract

Salt stress is a severe type of environmental stress. It adversely affects agricultural production worldwide. The overproduction of reactive oxygen species (ROS) is the most frequent phenomenon during salt stress. ROS are extremely reactive and, in high amounts, noxious, leading to destructive processes and causing cellular damage. However, at lower concentrations, ROS function as secondary messengers, playing a critical role as signaling molecules, ensuring regulation of growth and adjustment to multifactorial stresses. Plants contain several enzymatic and non-enzymatic antioxidants that can detoxify ROS. The production of ROS and their scavenging are important aspects of the plant’s normal response to adverse conditions. Recently, this field has attracted immense attention from plant scientists; however, ROS-induced signaling pathways during salt stress remain largely unknown. In this review, we will discuss the critical role of different antioxidants in salt stress tolerance. We also summarize the recent advances on the detrimental effects of ROS, on the antioxidant machinery scavenging ROS under salt stress, and on the crosstalk between ROS and other various signaling molecules, including nitric oxide, hydrogen sulfide, calcium, and phytohormones. Moreover, the utilization of “-omic” approaches to improve the ROS-regulating antioxidant system during the adaptation process to salt stress is also described.

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Crossref · 10.3390/plants12040864

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  • Increased salinity promotes the formation of reactive oxygen species (ROS), which can degrade chlorophyll and damage the photosynthetic machinery.

    “Furthermore, increased salinity levels promote the formation of reactive oxygen species (ROS), which can degrade chlorophyll and damage the photosynthetic machinery46.”

    From Cold plasma technology as a pre-treatment for seed priming enhances germination and reduces salinity stress in Prosopis Koelziana (2025) · cites this paper as [46]

    Section 5 (page unavailable) states that high salinity leads to ROS overproduction and that chloroplast activity is impaired, hindering photosynthesis. The passages do not establish the more specific claim that ROS degrade chlorophyll; Section 2 discusses chlorophyll’s role in ROS formation, not its degradation. (LLM, conf=0.84)

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Research works printed but not linked: 11

  1. [12]Mehla N. Sindhi V. Josula D. Bisht P. Wani S.H. An introduction to antioxidants and their roles in plant stress tolerance Reactive Oxygen Species and Antioxidant Systems in Plants: Role and Regulation under Abiotic Stress Springer Berlin/Heidelberg, Germany 2017 1 23
  2. [16]Hasanuzzaman M. Hossain M.A. Silva J.A. Fujita M. Plant response and tolerance to abiotic oxidative stress: Antioxidant defense is a key factor Crop Stress and Its Management: Perspectives and Strategies Springer Berlin/Heidelberg, Germany 2012 261 315
  3. [45]Maurya A.K. Oxidative stress in crop plants Agronomic Crops Springer Berlin/Heidelberg, Germany 2020 349 380
  4. [65]Scandalios J.G. Regulation and properties of plant catalases Causes of Photooxidative Stress and Amelioration of Defense Systems in Plants CRC Press Boca Raton, FL, USA 2019 275 316
  5. [66]Sharma I. Ahmad P. Catalase: A versatile antioxidant in plants Oxidative Damage to Plants Elsevier Amsterdam, The Netherlands 2014 131 148
  6. [88]Rao A. Reddy A.R. Glutathione reductase: A putative redox regulatory system in plant cells Sulfur Assimilation and Abiotic Stress in Plants Springer Berlin/Heidelberg, Germany 2008 111 147
  7. [95]Yousuf P.Y. Hakeem K.U.R. Chandna R. Ahmad P. Role of glutathione reductase in plant abiotic stress Abiotic Stress Responses in Plants Springer Berlin/Heidelberg, Germany 2012 149 158
  8. [106]Barnes J. Zheng Y. Lyons T. Plant resistance to ozone: The role of ascorbate Air Pollution and Plant Biotechnology Springer Berlin/Heidelberg, Germany 2002 235 252
  9. [144]Andersen O.M. Markham K.R. Flavonoids: Chemistry, Biochemistry and Applications CRC Press Boca Raton, FL, USA 2005
  10. [211]Kesawat M.S. Das B.K. Kumar M. Bhaganagare G.R. An overview on Fe–S protein biogenesis from prokaryotes to eukaryotes Biological Nitrogen Fixation Wiley Online Library Hoboken, NJ, USA 2015 57 74
  11. [245]Iqbal N. Masood A. Khan N.A. Phytohormones in salinity tolerance: Ethylene and gibberellins cross talk Phytohormones and Abiotic Stress Tolerance in Plants Springer Berlin/Heidelberg, Germany 2012 77 98

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Authors
Kesawat, M. S., Satheesh, N., Kherawat, B. S., Kumar, A., Kim, H.-U., Chung, S.-M., & Kumar, M.
Affiliations
  • Sri Sri University (IN)
  • Swami Keshwanand Rajasthan Agricultural University (IN)
  • Banaras Hindu University (IN)
  • Sejong University (KR)
  • Dongguk University (KR)
Corresponding author
Kumar, Manu
Venue
Plants
Publisher
MDPI AG
Published
2023-02-14
Volume
12
Issue
4
Pages
864
ISSN
2223-7747 (ISSN-L)
OpenAlex
W4320917863
Cited by
407
References
270
Citations by year
2026: 132 · 2025: 139 · 2024: 113 · 2023: 22 · 2013: 1
FWCI
9.70
Type
journal article
Language
en
Open access
Locations
  • Plants (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Research Foundation of Korea (NRF-2020R1A2C2008175)
  • Dongguk University Research Fund of 2020–2023 (NRF-2020R1A2C2008175)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant-Microbe Interactions and Immunity
Keywords
reactive oxygen species, salt stress, salt tolerance, antioxidant enzymes, non-enzymatic antioxidants, ROS signaling, nitric oxide, hydrogen sulfide, calcium signaling, plant hormones, oxidative stress, plant stress response, omics approaches

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