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Cited by 1,357

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Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications

Open access
Nguyen, Hoang, Park, Jeho, Kang, Sebyung, Kim, Moonil·2015·Sensors

Abstract

Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.

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Metadata

Authors
Nguyen, H., Park, J., Kang, S., & Kim, M.
Venue
Sensors
Publisher
MDPI AG
Published
2015-05-05
Volume
15
Issue
5
Pages
10481-10510
ISSN
1424-8220 (ISSN-L)
OpenAlex
W1963256408
Cited by
1,357
References
1
FWCI
39.32
Type
journal article
Language
en
Open access
gold

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