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Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications
Open accessAbstract
Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.
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Lin, H., Zhu, C., Shang, T., Zhu, N., Lin, K., Zhang, C., Shao, X., Wang, X., & Duan, H. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00896 · Cited by 10
Metadata
- Authors
- Nguyen, H., Park, J., Kang, S., & Kim, M.
- Venue
- Sensors
- Publisher
- MDPI AG
- Published
- 2015-05-05
- Volume
- 15
- Issue
- 5
- Pages
- 10481-10510
- ISSN
- 1424-8220 (ISSN-L)
- OpenAlex
- W1963256408
- Cited by
- 1,357
- References
- 1
- FWCI
- 39.32
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
