The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.
Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer
Open accessAbstract
Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer.
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“Dysregulated expression of sealing claudins and increased intestinal permeability contributes to a leaky epithelial barrier and may lead to intestinal infection and bowel symptoms of IBD patients [178,189].”
From Insights of Endocytosis Signaling in Health and Disease (2023) · cites this paper as [189]
In the citing paper
“The endocytosis of TJs and AJs happens similar to the internalization of luminal antigens into the enterocytes, and IBD patients have an increased ability to transcytosis of luminal antigens [189].”
From Insights of Endocytosis Signaling in Health and Disease (2023) · cites this paper as [189]
Citations
Cites
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
Hanauer, S. B., Feagan, B. G., Lichtenstein, G. R., Mayer, L., Schreiber, S., Colombel, J., Rachmilewitz, D., Wolf, D. C., Olson, A. D., Bao, W., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08512-4 · Cited by 4,164
Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis
Rutgeerts, P. J., Sandborn, W. J., Feagan, B. G., Reinisch, W., Olson, A. D., Johanns, J., Travers, S., Rachmilewitz, D., Hanauer, S. B., Lichtenstein, G. R., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050516 · Cited by 3,910
Inflammatory bowel disease: cause and immunobiology
Baumgart, D. C., & Carding, S. R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60750-8 · Cited by 2,147
Intestinal barrier function: molecular regulation and disease pathogenesis
Groschwitz, K. R., & Hogan, S. P. (2009) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.05.038 · Cited by 1,775
Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton
Hartsock, A., & Nelson, W. J. (2007) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.07.012 · Cited by 1,637
Claudin-based tight junctions are crucial for the mammalian epidermal barrier
Furuse, M., Hata, M., Furuse, K., Yoshida, Y., Haratake, A., Sugitani, Y., Noda, T., Kubo, A., & Tsukita, S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110122 · Cited by 1,512
Anderson, C., Boucher, G., Lees, C., Franke, A., D'Amato, M., Taylor, K., Lee, J., Goyette, P., Imieliński, M., Latiano, A., et al. (2011) · Nature Genetics · doi:10.1038/ng.764 · Cited by 1,361
Adenoma–linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
Grivennikov, S. I., Wang, K., Mucida, D., Stewart, C. A., Schnabl, B., Jauch, D., Taniguchi, K., Yu, G.-Y., Österreicher, C. H., Hung, K. E., et al. (2012) · Nature · doi:10.1038/nature11465 · Cited by 1,327
Heller, F., Florian, P., Bojarski, C., Richter, J. F., Christ, M., Hillenbrand, B., Mankertz, J., Gitter, A. H., Bürgel, N., Fromm, M., et al. (2005) · Gastroenterology · doi:10.1016/j.gastro.2005.05.002 · Cited by 1,232
Zeißig, S., Bürgel, N., Günzel, D., Richter, J. F., Mankertz, J., Wahnschaffe, U., Kroesen, A. J., Zeitz, M., Fromm, M., & Schulzke, J. (2006) · Gut · doi:10.1136/gut.2006.094375 · Cited by 1,218
Cited by
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Items 301–400 of 509
Chi, F., Qiu, F., Jin, X., Chen, L., He, G., & Han, S. (2022) · DNA and Cell Biology · doi:10.1089/dna.2021.0866 · Cited by 12
Pathophysiology of colitis-associated colorectal cancer
Neufert, C. F., & Neurath, M. F. (2026) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-026-01197-6 · Cited by 13
TNF-α induces Claudin-1 expression in renal tubules in Alport mice
Iida, M., Ohtomo, S., Wada, N. A., Ueda, O., Tsuboi, Y., Kurata, A., Jishage, K., & Horiba, N. (2022) · PLoS ONE · doi:10.1371/journal.pone.0265081 · Cited by 11
Chiba, T., & Maeda, T. (2023) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b22-00880 · Cited by 12
Xing, D., Zheng, T., Chen, X., & Xie, Z. (2024) · Foods · doi:10.3390/foods13172843 · Cited by 11
Li, Y., Wang, M., Su, J., Zhong, R., Yin, S., Zhao, Z., & Sun, Z. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.111490 · Cited by 11
Gp96 deficiency affects TLR4 functionality and impairs ERK and p38 phosphorylation
Cosín‐Roger, J., Spalinger, M. R., Ruiz, P. A., Stanzel, C., Terhalle, A., Wolfram, L., Melhem, H., Atrott, K., Lang, S., Frey-Wagner, I. M., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193003 · Cited by 11
Role of Csk in intestinal epithelial barrier function and protection against colitis
Sun, C., Murata, Y., Imada, S., Konno, T., Kotani, T., Saito, Y., Yamada, H., & Matozaki, T. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.08.140 · Cited by 11
Hung, Y.-K., Ho, S., Kuo, C.-Y., & Chen, M. (2021) · International Journal of Medical Sciences · doi:10.7150/ijms.53599 · Cited by 11
Wang, R., Yan, B., Yin, Y., Wang, X., Wu, M., Wen, T., Yin, Q., Wang, Y., Huang, C., & Zhu, Y. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.132441 · Cited by 10
Xu, X., Yuan, J., Zhu, M., Gao, J., Meng, X., Wu, Y., Li, X., Tong, P., & Chen, H. (2024) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70014 · Cited by 10
Ye, Y., Abulizi, A., Zhang, Y., Lu, F., An, Y., Lin, D., Ren, C., Zhang, H., Wang, Y., Chen, D., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062466 · Cited by 13
Hamdan, F. H., Farhadipour, M., Pérez, I., Kossick, K. F., Smith, H., Edwinson, A. L., de Hoyos‐Vega, J. M., Gonzalez, M. M., Chiang, D., Klatt, E. E., et al. (2026) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2026.101774 · Cited by 13
Rocha, B. S., Nunes, C., & Laranjinha, J. A. N. (2016) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2016.10.021 · Cited by 10
Zha, R., Ge, E., Guo, L., Gao, Q., Lin, Q., Zhou, W. P., Jin, X., Xie, W., Yin, H., & Liu, T. (2021) · Fitoterapia · doi:10.1016/j.fitote.2021.104916 · Cited by 10
Bekusova Viktoria, V., Evgeny, L. F., Okorokova, L. S., Natalia, M. K., Alexander, D. N., & Alexander, G. M. (2018) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2018.0016 · Cited by 10
Shi, F., Gao, Y., Han, S., Shi, H., Hou, Q., Gao, Y., Wen, X., Zhu, Z.-Y., Liu, K., Gong, W., et al. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106222 · Cited by 9
Prevalence of bronchiectasis in inflammatory bowel disease: a systematic review and meta-analysis
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Effect of probiotic extracellular vesicles and their applications on health and disease
Wang, G., Wang, Y., Sheng, K., & Wang, Y. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.14123 · Cited by 9
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Côco, L. Z., Belisário, E. D. S., Vasquez, E. C., Pereira, T. D. M. C., Aires, R., & Campagnaro, B. P. (2025) · Pharmacological Reports · doi:10.1007/s43440-025-00724-7 · Cited by 9
Feng, S., Raimi‐Abraham, B. T., & Vllasaliu, D. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.106925 · Cited by 9
Xu, C., Diao, J., Feng, Y., Zhang, S., Sheng, Y., & Wang, C. (2025) · Foods · doi:10.3390/foods14081363 · Cited by 9
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Chen, J., Gou, Z., Huang, Y., Yu, Q., Kim, A. N., Shi, W., & Zhou, Y. (2025) · Pharmaceuticals · doi:10.3390/ph18050695 · Cited by 9
Jing, Y., & Yan, D. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1538733 · Cited by 9
Ude, V. C., Brown, D. M., Maciaszek, K., Stone, V., & Johnston, H. J. (2019) · NanoImpact · doi:10.1016/j.impact.2019.100165 · Cited by 9
Kim, S., Chung, K., Jang, S.-Y., Han, H.-S., Heo, S.-W., Lee, J. K., Kim, H. J., Shin, Y., Ahn, H. S., Lee, S. H., et al. (2023) · Food & Function · doi:10.1039/d3fo01243c · Cited by 9
Normal Ileal Mucus Is Inadequate for Epithelial Protection in Ileal Pouch Mucosa
Knowles, J. P., & Church, J. M. (2024) · Diseases of the Colon & Rectum · doi:10.1097/dcr.0000000000003163 · Cited by 9
Gelmez, E., Jeron, A., & Bruder, D. (2022) · Cellular and Molecular Immunology · doi:10.1038/s41423-021-00817-2 · Cited by 9
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Fang, Y., & Zhan, X. (2022) · Digestion · doi:10.1159/000528084 · Cited by 9
Cui, D., Yang, X., Okuda, S., Ling, Y., Zhang, Z., Liu, Q., Yuan, W., & Yan, F. (2020) · Journal of International Medical Research · doi:10.1177/0300060520951023 · Cited by 9
Bianchimano, P., Iwanowski, K., Smith, E. M., Cantor, A., Leone, P., Bongers, G., Gonzalez, C. G., Yoon, H., Elias, J. E., Weiner, H. L., et al. (2023) · iScience · doi:10.1016/j.isci.2023.108143 · Cited by 8
Alhendi, A., & Naser, S. A. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1412800 · Cited by 9
Seo, S.-M., Kim, N. W., Yoo, E., Lee, J.-H., Kang, A.-R., Jeong, H.-B., Shim, W.-Y., Kim, D., Park, Y., Bae, K., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0311310 · Cited by 8
Zhao, M., Zhang, Y., Wu, Y., Li, Y., Liang, S., Yi, H., & Li, G. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.106046 · Cited by 8
Wang, T., Ou, Y., Xiong, W., Luo, L., Xu, Y., Chen, G., Peng, Y., Chen, Y., Zeng, H., Yu, Y., et al. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s519483 · Cited by 8
Yuan, Z., Zhang, Y., Zhang, X., Wang, L., Ling, G., & Zhang, P. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c04341 · Cited by 8
Cao, L., Niu, M., Tang, X., Wang, Y., Hu, X., & Dai, W. (2025) · Scientific Reports · doi:10.1038/s41598-025-12255-5 · Cited by 10
Rahaman, M. M., Wangchuk, P., & Sarker, S. (2025) · Mediators of Inflammation · doi:10.1155/mi/3181200 · Cited by 8
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Zheng, X., Jiang, W., Feng, L., Wu, P., Liu, Y., Jiang, J., Kuang, S., Tang, L. Y., & Zhou, X. (2021) · Aquaculture Research · doi:10.1111/are.15693 · Cited by 8
Thomas, S. S., Cha, Y., & Kim, K. (2022) · Journal of Medicinal Food · doi:10.1089/jmf.2022.k.0071 · Cited by 8
Park, T. G., Kim, Y. R., Park, S.-Y., Choi, K., Kim, K. J., & Kim, J. Y. (2023) · Food Science and Biotechnology · doi:10.1007/s10068-023-01292-3 · Cited by 9
Mehmood, T., Pichyangkura, R., & Muanprasat, C. (2023) · Polymers · doi:10.3390/polym15071681 · Cited by 8
Putra, C., Bello, D., Kelleher, S. L., Tucker, K. L., & Mangano, K. M. (2024) · NanoImpact · doi:10.1016/j.impact.2024.100498 · Cited by 8
Li, X., Fei, Y., Luo, X., Zhang, B., Wang, C., Adiham, A., Wang, L., & Gong, P. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.104886 · Cited by 9
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Lu, J. J., Maimaiti, M., Liu, H., Liu, W., Hui, W. J., Huang, X. L., & Gao, F. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s335293 · Cited by 8
Schälter, F., Frech, M., Dürholz, K., Lucas, S., Sarter, K., Lebon, L., Bieren, J. E., Dubey, L. K., Voehringer, D., Schett, G. A., et al. (2022) · International Journal for Parasitology · doi:10.1016/j.ijpara.2022.04.004 · Cited by 8
Go, E.-J., Ryu, B. R., Gim, G.-J., Shin, Y. R., Kang, M. J., Kim, M. J., Baek, J.-S., & Lim, J. D. (2025) · Pharmaceuticals · doi:10.3390/ph18040475 · Cited by 7
Petit, C., Rozières, A., Boschetti, G., Viret, C., Faure, M., Nancey, S., & Duclaux‐Loras, R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136133 · Cited by 8
Mendonça, R. L. D. S., Kanno, D. T., Campos, F. G., Pereira, G. P., Yoshitani, M. M., Delben, A. G., Pereira, J. A., & Martinez, C. A. R. (2022) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-022-05362-5 · Cited by 7
Monzani, R., Gagliardi, M., Clemente, N., Saverio, V., Pańczyszyn, E., Santoro, C., Yissachar, N., Visciglia, A., Pane, M., Amoruso, A., et al. (2022) · Biology · doi:10.3390/biology11111574 · Cited by 7
Lin, Y., Xie, Z., Li, Z., Yuan, C., Zhang, C., Li, Y., Xie, K., & Wang, K. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105935 · Cited by 7
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Kim, H.-Y., Seo, J. E., Lee, H., Bae, C., Ha, K., & Kim, S. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.946909 · Cited by 7
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Kim, M. S., Kim, Y. D., Kang, S., Kwon, O., Shin, J.-H., & Kim, J. Y. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104775 · Cited by 7
Chernyavskij, D. A., Galkin, I. I., Pavlyuchenkova, A. N., Fedorov, A. V., & Chelombitko, M. A. (2023) · Molecular Biology · doi:10.31857/s0026898423060058 · Cited by 7
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Xu, Y., Fang, M., Chen, Z., Jin, Z., Zhang, T., Yu, L., Ma, F., Lu, Z., Wang, H., Zhang, L., et al. (2025) · Food Research International · doi:10.1016/j.foodres.2025.116537 · Cited by 6
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Broering, M. F., Tocci, S., Sout, N. T., Reutelingsperger, C. P. M., Farsky, S. H. P., Das, S., & Sayed, I. M. (2024) · Stem Cell Reviews and Reports · doi:10.1007/s12015-024-10708-4 · Cited by 6
Diao, X., Yamada, K., Shibata, Y., & Imada, C. (2022) · Marine Drugs · doi:10.3390/md20020087 · Cited by 6
Cheng, K., Larabee, S. M., Tolaymat, M., Hanscom, M., Shang, A. C., Schledwitz, A., Hu, S., Drachenberg, C. B., Zhan, M., Chahdi, A., et al. (2021) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00415.2020 · Cited by 6
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Manzini, R., Schwarzfischer, M., Bircher, A., Niechcial, A., Vavricka, S. R., Atrott, K., Lang, S., Scharl, M. M., & Spalinger, M. R. (2021) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaa328 · Cited by 8
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Lee, K., Kumazoe, M., Marugame, Y., Fujimura, Y., & Tachibana, H. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.05.112 · Cited by 5
Eissa, N., Elgazzar, O., Hussein, H. H., Hendy, G. N., Bernstein, C. N., & Ghia, J. (2021) · Biomedicines · doi:10.3390/biomedicines9020134 · Cited by 5
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Song, Y., Zhang, J., Liang, S., Cao, Y., & Wang, Q. (2025) · Journal of Future Foods · doi:10.1016/j.jfutfo.2025.10.014 · Cited by 4
Li, Z., Gu, R., Liu, D., Zhang, Y., Qin, Y., Li, X., Qiao, Y., Li, Z., Guo, J., Wang, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-67034-7 · Cited by 4
Miao, G., Zhang, D. C., Sui, Z., Leng, J., Deng, Y., Gu, X., & Cao, H. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1725084 · Cited by 4
Xie, Q., Xu, H., Yang, X., Chen, Y., & Xu, Z. Z. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.103063 · Cited by 3
Lin, W.-C., Zhang, C., Lei, H., Cao, Z., Gao, X., Yu, W., Li, X., Xiang, Q., Zhang, Z.-W., Pang, S., et al. (2026) · iMeta · doi:10.1002/imt2.70134 · Cited by 4
Tian, Y., Li, X., Wang, X., Pei, S.-T., Pan, H., Cheng, Y., Li, Y., Cao, W.-T., Petersen, J.-D. D., & Zhang, P. (2024) · World Journal of Gastroenterology · doi:10.3748/wjg.v30.i10.1405 · Cited by 4
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Barrett, B. S., Nguyen, D. H. A., Xu, J., Guo, K., Shetty, S., Jones, S. T., Mickens, K. L., Shepard, C., Roers, A., Behrendt, R., et al. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2001389 · Cited by 4
Gao, S.-Y., Wu, X., Zhang, Y., Li, K., Wang, L.-T., & Liu, G. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.12.008 · Cited by 4
do Nascimento, R. D. P., Alves, M. D. R., Noguera, N. H., Lima, D. C., & Maróstica, M. R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99111-7.00014-3 · Cited by 3
Alhendi, A., & Naser, S. A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1562100 · Cited by 4
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Metadata
- Authors
- Landy, J., Ronde, E., English, N., Clark, S. K., Hart, A. L., Knight, S. C., Ciclitira, P. J., & Al-Hassi, H. O.
- Affiliations
- St Mark's Hospital (GB)
- St Thomas' Hospital (GB)
- Corresponding author
- Ciclitira, Paul J
- Venue
- World Journal of Gastroenterology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2016
- Volume
- 22
- Issue
- 11
- Pages
- 3117
- ISSN
- 1007-9327 (ISSN-L)
- PMC
- PMC4789987
- OpenAlex
- W2330707041
- Cited by
- 507
- References
- 103
- Citations by year
- 2026: 38 · 2025: 56 · 2024: 65 · 2023: 60 · 2022: 65 · 2021: 69 · 2020: 49 · 2019: 39 · 2018: 39 · 2017: 20 · 2016: 7
- FWCI
- 4.68
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- World Journal of Gastroenterology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Spiral (Imperial College London) (submittedVersion, other-oa)
- Funders
- Biotechnology and Biological Sciences Research Council
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Keywords
- tight junctions, inflammatory bowel disease, inflammatory bowel disease-associated colorectal cancer, claudins, intestinal epithelial barrier, paracellular permeability, intestinal inflammation, pathogenesis
- MeSH terms
- Animals, Anti-Inflammatory Agents, Colitis, Ulcerative, Colon, Crohn Disease, Humans, Intestinal Mucosa, Permeability, Colorectal Neoplasms, Inflammation Mediators, Tight Junctions, Pouchitis, Claudins
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