Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer

Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial

Hanauer, S. B., Feagan, B. G., Lichtenstein, G. R., Mayer, L., Schreiber, S., Colombel, J., Rachmilewitz, D., Wolf, D. C., Olson, A. D., Bao, W., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08512-4 · Cited by 4,164

Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis

Rutgeerts, P. J., Sandborn, W. J., Feagan, B. G., Reinisch, W., Olson, A. D., Johanns, J., Travers, S., Rachmilewitz, D., Hanauer, S. B., Lichtenstein, G. R., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050516 · Cited by 3,910

Inflammatory bowel disease: cause and immunobiology

Baumgart, D. C., & Carding, S. R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60750-8 · Cited by 2,147

Intestinal barrier function: molecular regulation and disease pathogenesis

Groschwitz, K. R., & Hogan, S. P. (2009) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.05.038 · Cited by 1,775

Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton

Hartsock, A., & Nelson, W. J. (2007) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.07.012 · Cited by 1,637

Claudin-based tight junctions are crucial for the mammalian epidermal barrier

Furuse, M., Hata, M., Furuse, K., Yoshida, Y., Haratake, A., Sugitani, Y., Noda, T., Kubo, A., & Tsukita, S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110122 · Cited by 1,512

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Anderson, C., Boucher, G., Lees, C., Franke, A., D'Amato, M., Taylor, K., Lee, J., Goyette, P., Imieliński, M., Latiano, A., et al. (2011) · Nature Genetics · doi:10.1038/ng.764 · Cited by 1,361

Adenoma–linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

Grivennikov, S. I., Wang, K., Mucida, D., Stewart, C. A., Schnabl, B., Jauch, D., Taniguchi, K., Yu, G.-Y., Österreicher, C. H., Hung, K. E., et al. (2012) · Nature · doi:10.1038/nature11465 · Cited by 1,327

Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution

Heller, F., Florian, P., Bojarski, C., Richter, J. F., Christ, M., Hillenbrand, B., Mankertz, J., Gitter, A. H., Bürgel, N., Fromm, M., et al. (2005) · Gastroenterology · doi:10.1016/j.gastro.2005.05.002 · Cited by 1,232

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease

Zeißig, S., Bürgel, N., Günzel, D., Richter, J. F., Mankertz, J., Wahnschaffe, U., Kroesen, A. J., Zeitz, M., Fromm, M., & Schulzke, J. (2006) · Gut · doi:10.1136/gut.2006.094375 · Cited by 1,218

Enhancing intestinal health with germinated oats: Bioinformatics and compound profiling insights into a novel approach for managing inflammatory bowel disease

Lee, H. J., Kim, K. J., Park, S.-Y., Choi, K., Pyee, J., Yoo, S., & Kim, J. Y. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.104833 · Cited by 3

A novel lutein-stevioside complex inhibits DSS-induced colitis

Dong, Y., Hao, M., Xu, Y., Feng, L., Li, D., Lian, Y., Wu, D., & Dai, Z. (2025) · Food Production Processing and Nutrition · doi:10.1186/s43014-025-00310-7 · Cited by 4

Mechanisms Underlying the Beneficial Role of Probiotics in Diarrheal Diseases: Host–Microbe Interactions

Kumar, A., Bhat, P., Borthakur, A., Alrefai, W. A., & Dudeja, P. K. (2018) · Springer eBooks · doi:10.1007/978-1-4939-7534-1_5 · Cited by 3

Effect of herb-partitioned moxibustion in improving tight junctions of intestinal epithelium in Crohn disease mediated by TNF-α-NF-κB-MLCK pathway

Yan-ling, G., Wang, Y., Guo, Y., Yi, S., Wang, Y., Zhou, J., Zhao, J., Wu, H., & Shi, Y. (2020) · Journal of Acupuncture and Tuina Science · doi:10.1007/s11726-020-1218-4 · Cited by 3

Copper-mediated shifts in transcriptomic responses of intestines in Bufo gargarizans tadpoles to lead stress

Zhang, S., Chen, A., Jiang, L., Liu, X., & Chai, L. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-25801-3 · Cited by 3

Aggregating gut: on the link between neurodegeneration and bacterial functional amyloidsPreprint

Wojciechowska, A. W., Wojciechowski, J. W., Zielińska, K., Söding, J., Kościółek, T., & Kotulska, M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.26.624671 · Cited by 3

Fucosylated chondroitin sulfate alleviates colonic barrier dysfunction in Parkinson’s disease via epithelial cell modulation and microecology restoration

Chen, Y., Zhuo, Y., Wan, S., Li, Y., Chen, S., Wang, G., & Wu, N. (2025) · Journal of Functional Foods · doi:10.1016/j.jff.2025.106753 · Cited by 2

Saccharin Supplementation Aggravates High-Fat-Diet-Induced Atherosclerosis through Lipid Metabolism Disorder and Intestinal-Impairment-Induced Endothelial Dysfunction in ApoE–/– Mice

Li, Y., Sun, Y., Wang, X., Liu, M., Luo, Y., Wang, X., & Zhang, H. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c05681 · Cited by 3

Engineering micelles with hydrophilic-lipophilic balance to overcome intestinal barrier for oral therapeutic application

Liu, K., Zhao, P., Chen, Y., Zhang, Y., Jin, J., & Wan, T. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102369 · Cited by 2

Duckweed (Wolffia globosa) improves intestinal epithelial barrier function induced by gut microbial metabolites in vitro

Charoensiddhi, S., Kato, R., Zhang, W., & Smid, S. D. (2025) · Food Chemistry Advances · doi:10.1016/j.focha.2025.101157 · Cited by 2

Akkermansia muciniphila alleviates antibiotic- and LPS-induced oxidative stress via the p38α MAPK–Nrf2 signaling axis

Ye, W.-Y., Feng, C.-X., Su, S.-Q., Wei, S., Mao, Y., Chen, Z., Su, Y., & Shan, Q.-W. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1753421 · Cited by 2

Rhubarb-derived extracellular vesicles co-delivered with dexamethasone via multi-layered assembly nanostrategy for targeted ulcerative colitis therapy

Wang, K., Shen, M., Luo, X., Li, L., Wu, M., Zhang, X., Zhu, H., & Du, Q. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.174750 · Cited by 2

Advanced engineering of microbiome-related therapeutics for targeted treatment of inflammatory bowel diseases

Kim, Y., Park, N., Cheng, X., & Lee, Y. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.114872 · Cited by 3

Multi-strain probiotics combined with fruit-vegetable powders for regulating intestinal inflammation and intestinal epithelial barrier

Lin, P., Hsu, Y.-C., Lin, Y.-K., Lin, Y., Lin, Y.-H., & Chiang, C. (2022) · International Food Research Journal · doi:10.47836/ifrj.29.2.04 · Cited by 2

Tight Junctions in the Inflamed Gut

Encarnacion‐Garcia, M. R., & Nava, P. (2022) · Springer eBooks · doi:10.1007/978-3-030-97204-2_6 · Cited by 2

Role of Synbiotics on Modulation of Inflammation

Verma, B., Ashique, S., Mishra, N., Kumar, N., Tyagi, N., Kumar, S., Ingawale, D. K., Mulgund, S. V., & Namdeo, A. G. (2024) · Springer eBooks · doi:10.1007/978-981-99-5575-6_2 · Cited by 2

Hydrogels of diet-derived electron donors restore epithelial hypoxia and reduce iNOS synthesis to inhibit inflammation-induced overgrowth of facultatively anaerobic bacteria for gut homeostasis

Cheng, S., Wang, H., He, X., Shao, Y., Ma, F., Huang, J., Hu, B., & Liu, Z. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114574 · Cited by 2

Anti-colitic effects of Centella asiatica (L.) Urb. juice via ERK/p38 and NF-κB signaling modulation and the characterization of a key marker compound

Shin, H. Y., Jeong, Y. Y., Kim, J., Shin, K., & Yu, K. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120657 · Cited by 2

Intercellular Network of Junctions of the Gastrointestinal Tract

Welcome, M. O. (2018) · Springer eBooks · doi:10.1007/978-3-319-91056-7_4 · Cited by 2

Principles of Epithelial Transport

Silverthorn, D. U. (2020) · Physiology in health and disease · doi:10.1007/978-3-030-52780-8_2 · Cited by 2

Research Progress of Oral Chinese Medicine in Treating Ulcerative Colitis and Its Pathogenesis

Rui, D. (2021) · Frontiers in Medical Science Research · doi:10.25236/fmsr.2021.030408 · Cited by 2

Irsogladine maleate alters expression of a tight junction protein in portal hypertensive gastropathy

Yokoyama, K., Irie, M., Tsuchiya, N., Yamauchi, E., Kawashima, M., Miyayama, T., Fukuda, H., Yamauchi, R., Umeda, K., Takata, K., et al. (2020) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.15259 · Cited by 1

Protective Effects of Peanut Sprouts from a Smart Farming System on the Barrier Function of Human Epithelial Cells

Kim, D. Y., Kim, S.-S., Choi, E.-J., Kim, H., Kim, D. H., Hong, S. M., Lee, S.-B., & Cho, H. (2024) · Preventive Nutrition and Food Science · doi:10.3746/pnf.2024.29.4.474 · Cited by 1

Guanidinoacetic acid attenuates high-fat diet induced colitis by targeting mitophagy and the gut microbiota in middle-aged mice

Zhao, J., Ji, B., Ji, B., Zhang, W., & Zhao, J. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.106587 · Cited by 1

Gut microbiome and nutritional strategies in gastrointestinal cancers: Clinical implications and therapeutic perspectives

Pacheco-Barcía, V., Méndez, A. M., Hernández-Jiménez, E., Jiménez‐Fonseca, P., Martín, A. J. M., Custodio‐Cabello, S., Palka-Kotlowska, M., Gonzalez-Diaz, I., & Cabezón‐Gutiérrez, L. (2025) · World Journal of Clinical Oncology · doi:10.5306/wjco.v16.i10.107877 · Cited by 1

Lactobacillus rhamnosus CLK101 protects against ulcerative colitis in mice via intestinal barrier repair, microbiota homeostasis maintenance, and inflammatory signaling suppression

Pu, S., Xu, Z., Liu, J., Huang, X., Yang, X., Li, Z., Zhang, Y., Sun, X., & Lin, L. (2025) · Food Quality and Safety · doi:10.1093/fqsafe/fyaf060 · Cited by 1

Hyperglycemia alters the gene and protein expression of CDC42 in small and large intestine of Sprague-Dawley rats

Stojanović, M., Mendoza‐Marí, Y., Rai, V., & Agrawal, D. K. (2026) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05479-6 · Cited by 1

Pharmacological Targeting of PARP‐1‐NLRP3 Inflammasome Pathway in Colitis‐Associated Colorectal Neoplasia: Effects of 3‐aminobenzamide and Olaparib

Singla, S., Pant, R., Кумар, В., Tikoo, K., & Jena, G. (2026) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70698 · Cited by 1

Castl: robust identification of spatially variable genes in spatial transcriptomics via an ensemble-based framework

Yu, Y., Yang, J., HE, P.-A., & Zheng, X. (2026) · Briefings in Bioinformatics · doi:10.1093/bib/bbag074

Crypt-Level Tight Junction Remodeling Is Associated with Disease Course and Clinical Outcomes in Inflammatory Bowel Disease

Tsounis, E. P., Geramoutsou, C., Pastras, P., Aggeletopoulou, I., Bosgana, P., Lourida, T., Διαμαντοπούλου, Γ., Ritsatou, S., Koniaris, E., Mantzaris, G. J., et al. (2026) · Cells · doi:10.3390/cells15080695 · Cited by 1

The role of claudins in the physiology and pathology of the digestive system

Wróbel, A., Kot, G., Malecka-Panas, E. I., Strachowska, M., Jacenik, D., & Mokrowiecka, A. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.153802 · Cited by 1

AKAP12-LMOD1 signaling defines stromal CAF activation and epithelial junction loss in colorectal cancer

Ye, Q.-W., Liu, Y.-J., Xu, G., Chen, Y., & Li, J.-P. (2026) · Scientific Reports · doi:10.1038/s41598-026-44680-5 · Cited by 1

Lactiplantibacillus plantarum as a multifunctional probiotic for inflammatory bowel disease: Mechanisms, synbiotic strategies, and delivery systems

Tao, W., Liu, W., Shi, X., Han, S., Shen, Y., Sun, W., Sha, Y., Wang, G., Chen, Y., & Ying, H. (2026) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2026.06.005 · Cited by 1

Portulaca oleracea L.-derived extracellular vesicle-like particles reprogram intestinal ILCs to alleviate inflammatory bowel disease and colitis-associated colorectal cancer

Zhong, H., Liu, Z., Zhao, Z., Yao, S., 宁德阳, Qiao, H., & Yu, H. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.07.044 · Cited by 1

Expression of apical junction complex proteins in colorectal mucosa of miniature dachshunds with inflammatory colorectal polyps

Yokoyama, N., Ohta, H., Kagawa, Y., LEELA-ARPORN, R., Dermlim, A., Nisa, K., Morita, T., Osuga, T., Sasaki, N., Morishita, K., et al. (2017) · Journal of Veterinary Medical Science · doi:10.1292/jvms.16-0479 · Cited by 1

Safe intake of an oral supplement containing carbohydrates and whey protein shortly before sedation to gastroscopy; a double blind, randomized trial.

de Aguilar-Nascimento, J. E., Caporossi, C., Metelo, J. S., Tanajura, G., Canevari-de-Oliveira, M., & Costa, R. D. C. (2014) · Nutrición Hospitalaria · doi:10.20960/nh.04451 · Cited by 13

Is the microbiome the cause of irritable bowel syndrome and inflammatory bowel disease? Lessons to consider from odontology

Andersson, O. P. (2023) · International Journal of Colorectal Disease · doi:10.1007/s00384-023-04406-9 · Cited by 3

Tight Junction Proteins as Emerging Drug Targets: Expanding the Horizons from Inflammation to Cancer

Garimella, S. V., Roy, R., Gampa, S. C., & Pandrangi, S. L. (2023) · Springer eBooks · doi:10.1007/978-981-99-2415-8_5 · Cited by 1

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

Huang, X., Li, H., Cheng, F., Wang, L., Cao, G., Wang, L., & Shi, L. (2023) · Animal Research and One Health · doi:10.1002/aro2.39 · Cited by 1

Comparative analysis of bisphenol A effects on HT-29 cell line and mouse intestinal organoids

Jang, E., & Ahn, C. (2024) · Journal of Biomedical Translational Research · doi:10.12729/jbtr.2024.25.3.107 · Cited by 1

Real meat shows good performance in maintaining colonic barrier function at a recommended amount of intake in mice

Xie, Y., Cai, L., Ibeogu, I. H., Zhou, G., & Li, C. (2024) · Food Frontiers · doi:10.1002/fft2.497 · Cited by 1

Nutritional Status, Diet, and Intestinal Permeability of Mexican Children with Autism Spectrum Disorders

Pedroza-García, K. A., Anaya‐Loyola, M. A., Ronquillo, D., Caamaño, M. D. C., Masuoka‐Ito, D., Palacios, J. R., & Rosado, J. L. (2024) · Gastroenterology Insights · doi:10.3390/gastroent15040064 · Cited by 1

Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis

Sun, Y., Pan, W., Zhang, J., Cui, Y., Wang, H., Ru, G., & Chen, L. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4271 · Cited by 1

Hesteetako hanturazko gaixotasuna: patogenia, tratamenduak eta mikrobiotan oinarritutako biomarkatzaileak

Peña‐Cearra, A., Fullaondo, A., & Abecia, L. (2022) · EKAIA Euskal Herriko Unibertsitateko Zientzi eta Teknologi Aldizkaria · doi:10.1387/ekaia.23519

Trace aminergic regulation of gastrointestinal inflammation

Gwilt, K. B. (2019) · Digital Repository Service (Northeastern University) · doi:10.17760/d20317947 · Cited by 1

Genetic variation of tight junction structures in intestinal inflammation

Norén, E. (2016) · Figshare

The Cellular Function of USP22 and its Role in Tissue Maintenance and Tumor Formation

Kosinsky, R. L. (2018) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-6724

Developing models of the small intestine

Dosh, R. H. (2018) · Sheffield Hallam University · doi:10.7190/shu-thesis-00131

Harnessing patient-derived organoids and microfluidics to investigate cholinergic regulation of the epithelial barrier

Hosic, S. (2019) · Digital Repository Service (Northeastern University) · doi:10.17760/d20317949

An in vitro investigation of biochemical and molecular markers of nanomaterial toxicity to the intestine

Ude, V. C. (2018)

Defective intestinal repair after short-term high fat diet due to loss of efferocytosisPreprint

Hill, A. A., Kim, M., Zegarra-Ruiz, D. F., Song, H. W., Renfroe, M. C., Major, A. M., Wu, W.-J. H., Norwood, K., & Diehl, G. E. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/790220

ARE THEY ALSO MIND COLONIZERS? EXPLORING THE ASSOCIATION BETWEEN GUT MICROBIOTA AND DEPRESSION

Ayeni, F. A., & Fadeyi, T. E. (2020) · FUDMA Journal of Sciences · doi:10.33003/fjs-2020-0402-24

Inflammatory Pathways and In Vivo Studies of Inflammatory Bowel Disease

Ribeiro, D., Freitas, M., de Oliveira, J. M. P. F., Corvo, M. L., Carvalho, F. D., & Fernandes, E. G. R. (2021) · Advances in medical diagnosis, treatment, and care (AMDTC) book series · doi:10.4018/978-1-7998-3580-6.ch001

Molecular investigation of tight junction proteins related to the small intestines

Ebangwese, S. E. (2020) · Syracuse University Libraries (Syracuse University)

Role of human gastrointestinal organoids in discovery and translational medicine

Calor, A. K., van Weissenbruch, M. M., & Senger, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821269-1.00010-2

Fatty acids from natural resources in inflammatory gastrointestinal diseases with specific focus on inflammatory bowel disease

Talar, M., Tarasiuk, A., Sałaga, M., & Fichna, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823482-2.00004-2

Papel da barreira epitelial intestinal na patogênese do diabetes melito tipo 2 experimental

de Oliveira, R. B. (2018) · doi:10.47749/t/unicamp.2018.1097423

Dendronan

Huang, X., Cui, S. W., & Phillips, G. O. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820104-6.00020-6

Dysfunction of transfer RNA modifications in inflammatory bowel diseasePreprint

Zhang, J., Zhang, Y., Xia, Y., & Sun, J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.18.492467

The role of the Glucocorticoid Receptor in intestinal inflammation and tumorigenesis in a murine model of colitis and colitis-associated colorectal cancer

Muzzi, C. (2022) · doi:10.53846/goediss-9400

Is the Microbiome the cause of Irritable Bowel Syndrome and Inflammatory Bowel Disease? Lessons to consider from odontologyPreprint

Andersson, O. (2022) · doi:10.31219/osf.io/mb7gw

The Effects of Different Histone Deacetylase Inhibitors on Hypoxia-induced Intestinal Epithelial Barrier Dysfunction and a Preliminary Exploration of the MechanismsPreprint

Chu, X., Di, C., Chen, S., Alam, H. B., & Chang, Z. (2022) · Research Square · doi:10.21203/rs.3.rs-2176731/v1

The role of Cdc42 Rho GTPase in the cystic fibrosis intestinal epithelial barrier

Woode, R. A. (2022) · MOspace Institutional Repository (University of Missouri) · doi:10.32469/10355/94269

Paneth and Paneth-like cells undergoing necroptosis fuel intestinal epithelial cell proliferation following IFN-γ stimulationPreprint

Encarnacion‐Garcia, M. R., la Torre‐Baez, R. D., Hernandez‐Cueto, M. A., Velázquez‐Villegas, L. A., Candelario‐Martínez, A., Horta‐López, P. H., Montoya‐García, A., Jaimes‐Ortega, G. A., Lopez-Bailon, L. U., Piedra-Quintero, Z. L., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.13.540666

Research Progress of PLEKHA Protein Family in Cancer

赵, 改. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.1351120

BMSC cells alleviate liver injury induced by ulcerative colitis via repairing the intestinal-liver barrier and activating hepatocyte growth factor

Deng, Z., Meng, Y., Zhao, L., Luo, W., Zhang, J., Hu, J., Jiang, H., & Zhang, Q. (2023) · Cellular and Molecular Biology · doi:10.14715/cmb/2022.69.2.4

Polyphenols from foxtail millet improve non-alcoholic fatty liver disease by regulating intestinal floraPreprint

Israr, G., An, Y., Qiao, Q., He, S., & Li, Z. (2024) · Research Square · doi:10.21203/rs.3.rs-4089478/v1

Additional file 3 of Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Zhou, L., Zhu, L., Wu, X., Hu, S., Zhang, S., Ning, M., Yu, J. Q., & Chen, M. (2023) · Figshare · doi:10.6084/m9.figshare.23884295

Additional file 2 of Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Zhou, L., Zhu, L., Wu, X., Hu, S., Zhang, S., Ning, M., Yu, J. Q., & Chen, M. (2023) · Figshare · doi:10.6084/m9.figshare.23884292

Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression Patterns

Magnusson, M. K., Bas‐Forsberg, A., Verveda, A., Sapnara, M., Lorent, J., Savolainen, O. I., Wettergren, Y., Strid, H., Simrén, M., & Öhman, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189886

Zonula occludens proteins and their impact on the cancer microenvironment

Kim, M.-H., & Cha, H. (2024) · Kosin Medical Journal · doi:10.7180/kmj.24.136

Investigating the Effects of Inhaled Diesel Exhaust Particles on Gut Microbiome, Intestinal Integrity, Systemic Inflammation, and Biomarkers of Cardiovascular Disease in Wildtype Mice

Phillippi, D. (2021) · doi:10.12794/metadc1873801

The effects of supplemental brewers yeast on postprandial amino acid concentrations in healthy adult sled dogs

Rummell, L. M., Templeman, J. R., Cargo-Froom, C. L., & Shoveller, A. K. K. (2025) · Journal of Animal Science · doi:10.1093/jas/skaf180

The Quasipaa spinosa skin peptide GFGFGGF prevents dextran sodium sulfate‐induced colitis by improving the intestinal barrier and gut microbiota

Su, Y., Gao, Y., Zhang, L., Zhang, Z., Li, G., Zhou, C., Su, D., Li, J., & Wu, D. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.70025

Utilizing the Therapeutic Potential of Stem Cells in Celiac Disease

Thakkar, S. (2025) · International journal of high school research · doi:10.36838/v7i7.64

A Localized GTEx Database and Its Potential Applications in Biomedical Research

Churakov, G. A., BELYAKOV, M., Sall, T. S., & Орлов, С. В. (2025) · Molecular Biology · doi:10.1134/s0026893325700293

The Potential Role of Microalgal Antioxidant Molecules on the Microbiota–Gut Axis in Inflammatory Bowel Diseases

Radice, R. P., Iannelli, V., Padula, F., Fabrizio, V. D., Δρόσος, Μ., Scopa, A., & Martelli, G. (2025) · Biomolecules · doi:10.3390/biom15111535

Additional file 1 of Bacillus licheniformis PF9 improves barrier function and alleviates inflammatory responses against enterotoxigenic Escherichia coli F4 infection in the porcine intestinal epithelial cells

Li, Q., Li, L., Chen, Y., Yu, C., Azevedo, P. A., Gong, J., & Yang, C. (2022) · Figshare · doi:10.6084/m9.figshare.20267777

Additional file 4 of Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Zhou, L., Zhu, L., Wu, X., Hu, S., Zhang, S., Ning, M., Yu, J., & Chen, M. (2023) · Figshare · doi:10.6084/m9.figshare.23884301

Additional file 5 of F. prausnitzii-derived extracellular vesicles attenuate experimental colitis by regulating intestinal homeostasis in mice

Ye, L., Wang, Y., Xiao, F., Wang, X., Li, X., Cao, R., Zhang, J., & Zhang, T. (2024) · Figshare · doi:10.6084/m9.figshare.26640304

Additional file 2 of F. prausnitzii-derived extracellular vesicles attenuate experimental colitis by regulating intestinal homeostasis in mice

Ye, L., Wang, Y., Xiao, F., Wang, X., Li, X., Cao, R., Zhang, J., & Zhang, T. (2024) · Figshare · doi:10.6084/m9.figshare.24572132

Additional file 1 of F. prausnitzii-derived extracellular vesicles attenuate experimental colitis by regulating intestinal homeostasis in mice

Ye, L., Wang, Y., Xiao, F., Wang, X., Li, X., Cao, R., Zhang, J., & Zhang, T. (2023) · Figshare · doi:10.6084/m9.figshare.24571846

Additional file 4 of F. prausnitzii-derived extracellular vesicles attenuate experimental colitis by regulating intestinal homeostasis in mice

Ye, L., Wang, Y., Xiao, F., Wang, X., Li, X., Cao, R., Zhang, J., & Zhang, T. (2024) · Figshare · doi:10.6084/m9.figshare.26640301

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