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trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

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Mozaffarian, Dariush, de Oliveira Otto, Marcia C, Lemaitre, Rozenn N, Fretts, Amanda M, Hotamisligil, Gokhan, Tsai, Michael Y, Siscovick, David S, Nettleton, Jennifer A·2013·The American Journal of Clinical Nutrition

DOI 10.3945/ajcn.112.045468PMC PMC3607658

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Abstract

Background Dairy consumption is linked to a lower risk of type 2 diabetes, but constituents responsible for this relation are not established. Emerging evidence suggests that trans-palmitoleate (trans 16:1n-7), a fatty acid in dairy and also partially hydrogenated oils, may be associated with a more favorable metabolic profile and less incident diabetes.Objective We investigated the association of trans-palmitoleate with metabolic risk and incident diabetes in a multiethnic US cohort.Design Phospholipid fatty acids and metabolic risk factors were measured in 2000-2002 among 2617 adults in the Multi-Ethnic Study of Atherosclerosis (MESA), a cohort of white, black, Hispanic, and Chinese Americans. In 2281 participants free of baseline diabetes, we also prospectively assessed the risk of new-onset diabetes (205 cases) from baseline to 2005-2007.Results trans-Palmitoleate concentrations correlated positively with self-reported consumption of whole-fat dairy, butter, margarine, and baked desserts and with other circulating biomarkers of both dairy fat and partially hydrogenated oil consumption, which suggested mixed dietary sources. After multivariable adjustment, trans-palmitoleate concentrations were associated with higher LDL cholesterol (quintile 5 compared with quintile 1: +6.4%; P-trend = 0.005), lower triglycerides (-19.1%; P-trend < 0.001), lower fasting insulin (-9.1%; P-trend = 0.002), and lower systolic blood pressure (-2.4 mm Hg; P-trend = 0.01). In prospective analyses, trans-palmitoleate was independently associated with lower incident diabetes (P-trend = 0.02), including a 48% lower risk in quintile 5 compared with quintile 1 (HR: 0.52; 95% CI: 0.32, 0.85). All findings were similar between men and women and between different race-ethnic subgroups.Conclusions Circulating trans-palmitoleate is associated with higher LDL cholesterol but also with lower triglycerides, fasting insulin, blood pressure, and incident diabetes in a multiethnic US cohort. Our findings support the need for further experimental and dietary intervention studies that target circulating trans-palmitoleate. The MESA trial was registered at clinicaltrials.gov as NCT00005487.

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Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423
Antihyperlipidemic and Biochemical Activities of Mcy Protein in Streptozotocin Induced Diabetic Rats
Marella, S., Maddirela, D. R., Badri, K. R., Kumar, M. V. J., & Chippada, A. R. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373954 · Cited by 5,938
Multi-Ethnic Study of Atherosclerosis: Objectives and Design
Bild, D. E. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf113 · Cited by 3,942
Methods for Trend Estimation from Summarized Dose-Response Data, with Applications to Meta-Analysis
Greenland, S., & Longnecker, M. P. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116237 · Cited by 2,353
Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism
Cao, H., Gerhold, K. A., Mayers, J. R., Wiest, M. M., Watkins, S. M., & Hotamışlıgil, G. S. (2008) · Cell · doi:10.1016/j.cell.2008.07.048 · Cited by 1,174
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Maedler, K., Oberholzer, J., Bucher, P., Spinas, G. A., & Donath, M. Y. (2003) · Diabetes · doi:10.2337/diabetes.52.3.726 · Cited by 552
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Erbay, E., Babaev, V. R., Mayers, J. R., Makowski, L., Charles, K. N., Snitow, M. E., Fazio, S., Wiest, M. M., Watkins, S. M., Linton, M. F., et al. (2009) · Nature Medicine · doi:10.1038/nm.2067 · Cited by 490
Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA)
Nettleton, J. A., Steffen, L. M., Mayer-Davis, E. J., Jenny, N. S., Jiang, R., Herrington, D. M., & Jacobs, D. R. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.6.1369 · Cited by 484
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Guillocheau, É., Legrand, P., & Rioux, V. (2019) · Biochimie · doi:10.1016/j.biochi.2019.12.004 · Cited by 33
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Sawh, M. C., Wallace, M., Shapiro, E. M., Goyal, N. P., Newton, K. P., Yu, E. L., Bross, C., Durelle, J., Knott, C. J., Gangoiti, J. A., et al. (2020) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000003040 · Cited by 31
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Jacobs, S., Schiller, K., Jansen, E. H. J. M., Fritsche, A., Weikert, C., di Giuseppe, R., Boeing, H., Schulze, M. B., & Kröger, J. (2014) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2014.18 · Cited by 30
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Chen, G., Li, Y., Zeng, F., Deng, G., Liang, J., Wang, J., Su, Y., Chen, Y., Mao, L., Liu, Z., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1784839 · Cited by 17
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Zou, Q., Wei, T., Zhang, N., Xian, N., Weng, C., Deng, Z., & Li, J. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c01097 · Cited by 16
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Cubillos, L., Campo, Y. E. D., Harbi, K., Keyserling, T. C., Samuel‐Hodge, C. D., & Reuland, D. S. (2017) · The Science of Diabetes Self-Management and Care · doi:10.1177/0145721717706030 · Cited by 14
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Koba, S., Takao, T., Shimizu, F., Ogawa, M., Ishii, Y., Yokota, Y., Furuyama, F., Tsunoda, F., Shoji, M., Harris, W. S., et al. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.02.025 · Cited by 13
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Luo, C., Liu, H., Wang, X., Xia, L., Huang, H., Peng, X., Xia, C., & Liu, L. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab102 · Cited by 13
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Scherf, B. D. (1961) · American Heart Journal · doi:10.1016/0002-8703(61)90564-6 · Cited by 13
High-Fat Dairy Products May Decrease the Risk of Chronic Kidney Disease Incidence: A Long-Term Prospective Cohort Study
Gaeini, Z., Bahadoran, Z., Mirmiran, P., Feyzi, Z., & Azizi, F. (2022) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2022.10.003 · Cited by 12
Individual Fatty Acids in Cardiometabolic Disease
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Dietary Fatty Acids and the Metabolic Syndrome: A Personalized Nutrition Approach
O'Connor, S. E., & Rudkowska, I. (2018) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2018.07.004 · Cited by 13
Trans -palmitoleic acid, a dairy fat biomarker, stimulates insulin secretion and activates G protein-coupled receptors with a different mechanism from the cis isomer
Korkus, E., Szustak, M., Madaj, R., Chworoś, A., Drzazga, A. K., Koziołkiewicz, M., Dąbrowski, G., Czaplicki, S., Konopka, I., & Gendaszewska‐Darmach, E. (2023) · Food & Function · doi:10.1039/d2fo03412c · Cited by 11
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Muñoz‐Alvarez, K. Y., Gutiérrez‐Aguilar, R., & Frigolet, M. E. (2024) · Nutrition Bulletin · doi:10.1111/nbu.12657 · Cited by 11
Comparing the simultaneous determination of cis- and trans-palmitoleic acid in fish oil using HPLC and GC
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Ahmadi, E., Abdollahzad, H., Pasdar, Y., Rezaeian, S., Moludi, J., Nachvak, S. M., & Mostafai, R. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s247412 · Cited by 11
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Matthan, N. R., Lovato, L., Petersen, K. S., Kris‐Etherton, P. M., Sabaté, J., Rajaram, S., Li, Z., Reboussin, D. M., & Lichtenstein, A. H. (2024) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2024.08.002 · Cited by 10
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Guan, B., Sun, Y., Liu, X., Zhong, C., Li, D., Shan, X., Hui, X., Lu, C., Huo, Y., Sun, R., et al. (2024) · Food Chemistry X · doi:10.1016/j.fochx.2024.101375 · Cited by 9
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DA, G. D. H. (2014) · Primary Health Care Open Access · doi:10.4172/2167-1079.1000161 · Cited by 6
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Authors: Mozaffarian, D., de Oliveira Otto, M. C., Lemaitre, R. N., Fretts, A. M., Hotamisligil, G., Tsai, M. Y., Siscovick, D. S., & Nettleton, J. A.
Affiliations: Harvard University (US)
University of Washington (US)
University of Minnesota (US)
The University of Texas Health Science Center at Houston (US)
ORCID: Mozaffarian, Dariush
Fretts, Amanda M
Tsai, Michael Y
Siscovick, David S
Venue: The American Journal of Clinical Nutrition
Publisher: Elsevier BV
Published: 2013-04
Volume: 97
Issue: 4
Pages: 854-861
ISSN: 0002-9165 (ISSN-L)
DOI: 10.3945/ajcn.112.045468
PMC: PMC3607658
OpenAlex: W2151042915
Cited by: 270
References: 29
Citations by year: 2026: 9 · 2025: 4 · 2024: 12 · 2023: 15 · 2022: 26 · 2021: 20 · 2020: 27 · 2019: 32 · 2018: 21 · 2017: 24 · 2016: 26 · 2015: 27 · 2014: 19 · 2013: 6
FWCI: 24.13
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3612 d)
Locations: American Journal of Clinical Nutrition (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01hc095169-003, n01hc95159-40-0-1)
National Heart, Lung, and Blood Institute (N01 HC-95159, R01HL085710, N01 HC95169)
National Institute of Diabetes and Digestive and Kidney Diseases (K01DK082729)
National Center for Research Resources (RR024156)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
Keywords: trans-palmitoleic acid, milk fat, type 2 diabetes, new-onset diabetes, partially hydrogenated oils, LDL cholesterol, triglycerides, fasting insulin, blood pressure, phospholipid fatty acids, dairy consumption, metabolic risk, Multi-Ethnic Study of Atherosclerosis, racial and ethnic differences, dietary biomarkers, butter, margarine
MeSH terms: Aged, Blood Pressure, Dairy Products, Diabetes Mellitus, Diet, Dietary Fats, Ethnicity, Fatty Acids, Monounsaturated, Female, Humans, Hydrogenation, Insulin, Lipids, Cholesterol, LDL, Male, Middle Aged, Phospholipids, Prospective Studies, Risk Factors, Triglycerides, United States, Biomarkers, Trans Fatty Acids, Atherosclerosis

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trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

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