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Cited by 138Nutritional Studies and DietCardiovascular Health and Risk FactorsNutrition, Genetics, and Disease

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Dietary patterns and incident cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis

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Nettleton, Jennifer A, Polak, Joseph F, Tracy, Russell, Burke, Gregory L, Jacobs, David R·2009·The American Journal of Clinical Nutrition
DOI 10.3945/ajcn.2009.27597PMC PMC2728647
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Abstract

Background Empirically derived dietary patterns show strong cross-sectional associations with cardiovascular disease (CVD) risk factors in the Multi-Ethnic Study of Atherosclerosis (MESA).Objective We investigated associations between dietary patterns and risk of incident CVD in 5316 men and women.Design White, black, Hispanic, and Chinese adults aged 45-84 y and free of CVD and diabetes completed food-frequency questionnaires at baseline. Dietary patterns were derived by using principal components analysis. Incident CVD events (n = 207) identified over a median of 4.6 y were verified by death certificates and medical records.Results The Fats and Processed Meat dietary pattern was associated with a greater risk (hazard ratio quintile 5 compared with quintile 1: 1.82; 95% CI: 0.99, 3.35), and the Whole Grains and Fruit dietary pattern was associated with a lower risk (0.54; 0.33, 0.91) of CVD after adjustment for demographic and lifestyle confounders. Associations between CVD and the Whole Grains and Fruit dietary pattern remained strong after adjustment for waist circumference, blood pressure, lipids, or inflammatory markers.Conclusions Data from this multiethnic cohort reinforce findings from predominantly white cohorts, ie, that "healthy" and "unhealthy" dietary patterns empirically exist and that these patterns are important lifestyle predictors of CVD incidence.

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Metadata

Authors
Nettleton, J. A., Polak, J. F., Tracy, R., Burke, G. L., & Jacobs, D. R.
Affiliations
University of Vermont (US)
Corresponding author
Nettleton, Jennifer A
ORCID
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
2009-09
Volume
90
Issue
3
Pages
647-654
ISSN
0002-9165 (ISSN-L)
DOI
10.3945/ajcn.2009.27597
PMC
PMC2728647
OpenAlex
W2160611992
Cited by
138
References
16
Citations by year
2026: 7 · 2025: 5 · 2024: 4 · 2023: 8 · 2022: 4 · 2021: 4 · 2020: 9 · 2019: 4 · 2018: 4 · 2017: 10 · 2016: 10 · 2015: 14 · 2014: 11 · 2013: 16 · 2012: 11
FWCI
9.37
Type
journal article
Language
en
Open access
Licence
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (n01hc95164-17-0-1, n01hc95165-34-0-1, n01hc95161-24-0-1, n01hc95166-21-0-1, n01hc95162-31-0-1, n01hc95160-18-0-1, n01hc95163-22-0-1, n01hc95159-40-0-1)
  • National Heart, Lung, and Blood Institute (N01 HC-95159, N01-HC-95160, (N01-HC-95163, N01 HC-95161, N01 HC95165, N01HC95164, N01‐HC‐95166, N01-HC-95159 through N01-HC-95166, N01 HC-95162)
  • National Center for Research Resources (N01-HC-95166, N01-HC-95159, M01RR000645, M01 RR00645)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Nutrition, Genetics, and Disease
Keywords
dietary habits, cardiovascular disease incidence, healthy eating, unhealthy diet, Multi-Ethnic Study of Atherosclerosis, multi-ethnic cohort, cardiovascular risk factors
MeSH terms
Animals, Black or African American, Cardiovascular Diseases, Edible Grain, Diet, Diet Surveys, Dietary Fats, Female, Fruit, Hispanic or Latino, Humans, Male, Meat, Middle Aged, Risk Factors, United States, Health Behavior, Incidence, White People, Asian People, Atherosclerosis

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