Antimicrobial activity of Iberian macroalgae
Open accessAbstract
The antibacterial and antifungal activity of 82 marine macroalgae (18 Chlorophyceae, 25 Phaeophyceae and 39 Rhodophyceae) was studied to evaluate their potential for being used as natural preservatives in the cosmetic industry. The bioactivity was analysed from crude extracts of fresh and lyophilised samples against three Gram-positive bacteria, two Gram-negative bacteria and one yeast using the agar diffusion technique. The samples were collected seasonally from Mediterranean and Atlantic coasts of the Iberian Peninsula. Of the macroalgae analysed, 67% were active against at least one of the six test microorganisms. The highest percentage of active taxa was found in Phaeophyceae (84%), followed by Rhodophyceae (67%) and Chlorophyceae (44%). Nevertheless, red algae had both the highest values and the broadest spectrum of bioactivity. In particular, Bonnemaisonia asparagoides, Bonnemaisonia hamifera, Asparagopsis armata and Falkenbergia rufolanosa (Bonnemaisoniales) were the most active taxa. Bacillus cereus was the most sensitive test microorganism and Pseudomonas aeruginosa was the most resistant. The highest percentages of active taxa from Phaeophyceae and Rhodophyceae were found in autumn, whereas they were found in summer for Chlorophyceae.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The bioactivity of the same seaweed species could vary depending on the geographical zone due to environmental and seasonal parameters.
“In recent years, seaweeds have been recognized as producers of an enormous range of biologically active compounds, but the bioactivity of the same species could vary depending on the geographical zone due to environmental and seasonal parameters [75].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [75]
Algae produce bioactive compounds with rich pharmacological potential as a response to environmental conditions or characteristics such as competition for space, maintenance of unfolded surfaces, and repulsion of predators.
“Algae produce bioactive compounds with rich pharmacological potential. They generate these compounds as a response to environmental conditions or characteristics (competition for space, maintenance of unfolded surfaces, repulsion of predators, etc.) [75].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [75]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Antibacterial and Antifungal Activities of Nine Medicinal Plants from Zaire
Muanza, D. N., Kim, B. W., Euler, K. L., & Williams, L. (1994) · Pharmaceutical Biology · doi:10.3109/13880209409083012 · Cited by 280 · see citing works
Hornsey, I. S., & Hide, D. (1974) · British Phycological Journal · doi:10.1080/00071617400650421 · Cited by 157 · see citing works
Antibiotic Activity of some Marine Algae of Puerto Rico
Burkholder, P. R., Burkholder, L. M., & Almodóvar, L. R. (1960) · Botanica Marina · doi:10.1515/botm.1960.2.1-2.149 · Cited by 150 · see citing works
Antimicrobial activity from marine algae: Results of a large-scale screening programme
Reichelt, J. L., & Borowitzka, M. A. (1984) · Springer eBooks · doi:10.1007/978-94-009-6560-7_26 · Cited by 142 · see citing works
Antibacterial Activity of Indian Seaweed Extracts
Rao, P. S., & Parekh, K. S. (1981) · Botanica Marina · doi:10.1515/botm.1981.24.11.577 · Cited by 120 · see citing works
Antimicrobial activity from marine algae: Results of a large-scale screening programme
Reichelt, J. L., & Borowitzka, M. A. (1984) · Hydrobiologia · doi:10.1007/bf00027657 · Cited by 118 · see citing works
Antimicrobial and Antiviral Activities of Some Marine Algae from Eastern Sicily
Caccamese, S., Azzolina, R., Furnari, G., Cormaci, M., & Grasso, S. (1981) · Botanica Marina · doi:10.1515/botm.1981.24.7.365 · Cited by 114 · see citing works
Pesando, D., & Caram, B. (1984) · Botanica Marina · doi:10.1515/botm.1984.27.8.381 · Cited by 109 · see citing works
Bhosale, S. H., Nagle, V. L., & Jagtap, T. G. (2002) · Marine Biotechnology · doi:10.1007/s10126-001-0087-1 · Cited by 104 · see citing works
Biological Activity of Extracts from Some Mediterranean Macrophytes
Ballesteros, E., Martin, D. J., & Uriz, M. J. (1992) · Botanica Marina · doi:10.1515/botm.1992.35.6.481 · Cited by 99 · see citing works
Fatty acids as antimicrobial substances in brown algae
Rosell, K., & Srivastava, L. M. (1987) · Springer eBooks · doi:10.1007/978-94-009-4057-4_69 · Cited by 94 · see citing works
Biological Activities of Selected Marine Natural Products
König, G. M., Wright, A., Sticher, O., et al. (1994) · Planta Medica · doi:10.1055/s-2006-959565 · Cited by 94 · see citing works
Screening of Some Marine Plants from the Indian Coast for Biological Activity
Naqvi, S. S. W. A., Kamat, S. Y., Fernandes, L., et al. (1981) · Botanica Marina · doi:10.1515/botm.1981.24.1.51 · Cited by 82 · see citing works
Antibiotic activity of lipid-soluble extracts from Caribbean marine algae
Ballantine, D. L., Gerwick, W. H., Vélez, S. M., Alexander, E., & Guevara, P. (1987) · Springer eBooks · doi:10.1007/978-94-009-4057-4_68 · Cited by 78 · see citing works
Antibiotic activity of lipid-soluble extracts from Caribbean marine algae
Ballantine, D. L., Gerwick, W. H., Vélez, S. M., Alexander, E., & Guevara, P. (1987) · Hydrobiologia · doi:10.1007/bf00046168 · Cited by 76 · see citing works
Padmakumar, K., & Ayyakkannu, K. (1997) · Botanica Marina · doi:10.1515/botm.1997.40.1-6.507 · Cited by 73 · see citing works
Report on Antibiotic Activity of Seaweed Extracts*†
Pratt, R., Mautner, H. G., Gardner, G. M., Sha, Y.-H., & Dufrénoy, J. (1951) · Journal of the American Pharmaceutical Association (Scientific ed ) · doi:10.1002/jps.3030401115 · Cited by 64 · see citing works
SHORT COMMUNICATION. Antimicrobial and Antineoplastic Activity in Some South Florida Seaweeds
Hodgson, L. M. (1984) · Botanica Marina · doi:10.1515/botm.1984.27.8.387 · Cited by 56 · see citing works
Antimicrobial and Antiviral Activities of Extracts from Mediterranean Algae
Caccamese, S., Azzolina, R., Furnari, G., et al. (1980) · Botanica Marina · doi:10.1515/bot-1980-230503 · Cited by 56 · see citing works
PRELIMINARY SURVEY OF FUNGISTATIC PROPERTIES OF MARINE ALGAE
Welch, A. M. (1962) · Journal of Bacteriology · doi:10.1128/jb.83.1.97-99.1962 · Cited by 55 · see citing works
Fatty acids as antimicrobial substances in brown algae
Rosell, K., & Srivastava, L. M. (1987) · Hydrobiologia · doi:10.1007/bf00046169 · Cited by 54 · see citing works
Hornsey, I. S., & Hide, D. (1985) · British Phycological Journal · doi:10.1080/00071618500650041 · Cited by 52 · see citing works
Antimicrobial activity of some american algae
G., R. M. P., A., J. G. A., G., S. P., C., A. M., & C., G. M. (1990) · Journal of Ethnopharmacology · doi:10.1016/0378-8741(90)90104-2 · Cited by 49 · see citing works
Antimicrobial and cytotoxic terpenoids from tropical green algae of the family Udoteaceae
Fenical, W., & Paul, V. J. (1984) · Springer eBooks · doi:10.1007/978-94-009-6560-7_20 · Cited by 47 · see citing works
Horikawa, M., Noro, T., & Kamei, Y. (1999) · The Journal of Antibiotics · doi:10.7164/antibiotics.52.186 · Cited by 42 · see citing works
Seaweeds in pharmaceutical studies and applications
Baker, J. T. (1984) · Hydrobiologia · doi:10.1007/bf00027635 · Cited by 42 · see citing works
Seaweeds in pharmaceutical studies and applications
Baker, J. T. (1984) · Springer eBooks · doi:10.1007/978-94-009-6560-7_4 · Cited by 41 · see citing works
Martí, R., Uriz, M., & Turón, X. (2004) · Marine Ecology Progress Series · doi:10.3354/meps282073 · Cited by 37 · see citing works
Kumar, K. A., & Rengasamy, R. (2000) · Botanica Marina · doi:10.1515/bot.2000.042 · Cited by 37 · see citing works
Antibiotic (Fungicidal) Action from Extracts of Some Seaweeds
Khaleafa, A. F., Kharboush, M. A. M., Metwalli, A. A., Mohsen, A., & Serwi., A. (1975) · Botanica Marina · doi:10.1515/botm.1975.18.3.163 · Cited by 36 · see citing works
Melo, V. M. M., MEDEIROS, D. A. D. F., Rios, D. A. M., et al. (1997) · Botanica Marina · doi:10.1515/botm.1997.40.1-6.281 · Cited by 35 · see citing works
Antifungal and antibacterial screening of Dictyotales from the French Mediterranean coast
Moreau, J., Pesando, D., & Caram, B. (1984) · Hydrobiologia · doi:10.1007/bf00027737 · Cited by 34 · see citing works
Antifungal and antibacterial screening of Dictyotales from the French Mediterranean coast
Moreau, J., Pesando, D., & Caram, B. (1984) · Springer eBooks · doi:10.1007/978-94-009-6560-7_106 · Cited by 32 · see citing works
Antimicrobial activity of extracts from some Canary species of Phaeophyta and Chlorophyta
Febles, C. I., Arias, Á., Hardisson, A., et al. (1995) · Phytotherapy Research · doi:10.1002/ptr.2650090517 · Cited by 32 · see citing works
Rao, P. P. S., Rao, P. S., & Karmarkar, S. M. (1986) · Botanica Marina · doi:10.1515/botm.1986.29.6.503 · Cited by 31 · see citing works
Screening of Marine Algae from Brazilian Northeastern Coast for Antimicrobial Activity
de Campos‐Takaki, G. M., Diu, M. B. S., Koening, M. L., et al. (1988) · Botanica Marina · doi:10.1515/botm.1988.31.5.375 · Cited by 31 · see citing works
(2000) · Time to knit · doi:10.1016/s0967-0653(98)82260-6 · Cited by 31 · see citing works
Centeno, P. O. R., & Ballantine, D. L. (1999) · Journal of Applied Phycology · doi:10.1023/a:1008113108834 · Cited by 29 · see citing works
Screening of Argentine marine algae for antimicrobial activity
Espeche, M. E., Fraile, E. R., & Mayer, A. M. S. (1984) · Springer eBooks · doi:10.1007/978-94-009-6560-7_107 · Cited by 20 · see citing works
Antibacterial and antifungal activities of marine algae from karachi seashore of pakistan
Usmanghani, K., Shameel, M., Sualeh, M., Khan, K., & Mahmood, Z. (1984) · Fitoterapia · Cited by 16 · see citing works
Screening for antimicrobial activities in marine algae from the Qingdao coast, China
Jing-wen, M., & Wei-ci, T. (1984) · Springer eBooks · doi:10.1007/978-94-009-6560-7_105 · Cited by 12 · see citing works
Screening for antimicrobial activities in marine algae from the Qingdao coast, China
Jing-wen, M., & Wei-ci, T. (1984) · Hydrobiologia · doi:10.1007/bf00027736 · Cited by 11 · see citing works
Screening of Argentine marine algae for antimicrobial activity
Espeche, M. E., Fraile, E. R., & Mayer, A. M. S. (1984) · Hydrobiologia · doi:10.1007/bf00027738 · Cited by 10 · see citing works
ANTIMIKROBIELLE INHALTSSTOFFE IN ALGEN
Glombitza, K. ‐. (1970) · Planta Medica · doi:10.1055/s-0028-1099779 · Cited by 9 · see citing works
Sobre la actividad antibiotica de ciertas especies de algas del Mediterraneo
Golobardes, M. D. S., Mariné, M. D. L. C. H., & Camba, J. A. S. (1982) · Cited by 3 · see citing works
Soler, N. S., Siguán, M. A. R., & Garreta, A. G. (2006) · Complutensian Scientific Journals (Complutense University of Madrid) · doi:10.5209/bocm.7120 · Cited by 2 · see citing works
(2000) · Time to knit · doi:10.1016/s0967-0653(98)85211-3 · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- Chesters, C.G. and J.A. Stott. -1956. Production of antibiotic sub- stances by seaweeds. Proc. Int. Seaweed Symp., 2: 49-54.
- Della Pietà, F., L. Panizzi, P.L. Cioni, F. Cinelli and I. Morelli. - 1996. Attività antimicrobica di estratti di Caulerpa taxifolia su batteri e micetti terrestri. In: M.A. Ribera, E. Ballesteros, C.F. Boudouresque, A. Gómez and V. Gravez (eds.). Second International Workshop on Caulerpa taxifolia, pp. 261-264. Publ. Univ. Barcelona, Barcelona.
- Pesando, D. -1990. Antibacterial and antifungal activities of marine algae. In: I. Akatsuka (ed.), Introduction to Applied Phycology, pp. 3-26. SPB Academic Publishing, The Hague.
Cited by
Sorted by citations
The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value
Gomez-Zavaglia, A., Prieto Lage, M. A., Jimenez-Lopez, C., Mejuto, J. C., & Simal-Gandara, J. (2019) · Antioxidants · doi:10.3390/antiox8090406 · Cited by 280 · see citing works
Moubayed, N. M. S., Al Houri, H. J., Al Khulaifi, M. M., & Al Farraj, D. A. (2017) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2016.05.018 · Cited by 145 · see citing works
New Insights into the Culture Method and Antibacterial Potential of Gracilaria gracilis
Capillo, G., Savoca, S., Costa, R., Sanfilippo, M., Rizzo, C., Lo Giudice, A., Albergamo, A., Rando, R., Bartolomeo, G., Spanò, N., et al. (2018) · Marine Drugs · doi:10.3390/md16120492 · Cited by 79 · see citing works
- Authors
- Salvador, N., Gómez Garreta, A., Lavelli, L., & Ribera, M. A.
- Affiliations
- Universitat de Barcelona (ES)
- Venue
- Scientia Marina
- Publisher
- Editorial CSIC
- Published
- 2007-03-30
- Volume
- 71
- Issue
- 1
- Pages
- 101-114
- ISSN
- 0214-8358 (ISSN-L)
- 1886-8134
- OpenAlex
- W2108894176
- Cited by
- 220
- References
- 47
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 9 · 2023: 10 · 2022: 18 · 2021: 18 · 2020: 16 · 2019: 12 · 2018: 16 · 2017: 11 · 2016: 14 · 2015: 14 · 2014: 10 · 2013: 10 · 2012: 14
- FWCI
- 12.55
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Scientia Marina (publishedVersion, cc-by)
- Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona) (publishedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- RECERCAT (Consorci de Serveis Universitaris de Catalunya) (submittedVersion, cc-by-nc)
- Funders
- Universitat de Barcelona
- Università di Pisa
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Keywords
- seaweed, antimicrobial activity, antibacterial activity, antifungal activity, natural preservatives, cosmetic preservatives, Iberian Peninsula, brown algae, red algae, Chlorophyceae, Bonnemaisonia, Asparagopsis armata, seasonal variation, Bacillus cereus, Pseudomonas aeruginosa, crude extract
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
