Antimicrobial, antioxidant properties and chemical composition of seaweeds collected from Saudi Arabia (Red Sea and Arabian Gulf)
Open accessAbstract
The present study demonstrates the antibacterial activity of selected brown and green marine algae collected from Saudi Arabia Red Sea and Arabian Gulf. The methanolic and acetone extracts were tested against gram positive, gram negative bacteria and Candida albicans in an attempt to be used as an alternative to commonly used antibiotics. Both brown seaweed species Sargassum latifolium B and Sargassum platycarpum A methanolic extracts were found to be active against gram positive than gram negative; however, S. latifolium acetone extract gave the highest inhibitory activity against Salmonella sp. On the other hand, Cladophorasocialis organic extract demonstrated higher antibacterial activity than the fresh extract but both C. socialis extracts revealed decreased activity compared to Sargassum extracts. Cladophora methanolic extract showed an obvious effect on methicillin resistant Staphylococcus aureus (MRSA). The present work shows a comparable therapeutic potency of the tested seaweed members Sargassum and Cladophora extracts in treating human microbial pathogens to synthetic chemical antibiotics. A remarkable higher antioxidant DPPH free radical scavenging effect was recorded with Sargassum sp. compared to Cladophora sp. FTIR Infrared Spectrometer analysis together with the high performance liquid chromatography provided a detailed description of the possible functional constituents and the major chemical components present in marine macroalgae particularly in brown seaweeds to be mainly of phenolic nature to which the potent antimicrobial activity is being attributed.
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Seaweed antioxidant capacity in vitro is attributed to the presence of new antioxidant compounds like carotenoids, certain polysaccharides, and polyphenols, which show scavenger activity and can neutralize reactive oxygen species through their own oxidation.
“Different researches have demonstrated seaweed antioxidant capacity in vitro, attributed to the presence of new antioxidant compounds like carotenoids, certain polysaccharides, and polyphenols, which show scavenger activity, being able to neutralize those reactive oxygen species through their own oxidation, since their affinity to those oxidative compounds is very high [56,68,80,81,82,83,84,85].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [81]
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Cites
Oxidative stress and cancer: Have we moved forward?
Halliwell, B. (2007) · Biochemical Journal · doi:10.1042/bj20061131 · Cited by 1,302 · see citing works
Medicinal and pharmaceutical uses of seaweed natural products: A review
Smit, A. J. (2004) · Journal of Applied Phycology · doi:10.1023/b:japh.0000047783.36600.ef · Cited by 806 · see citing works
(1956) · Soil Science Society of America Journal · doi:10.2136/sssaj1956.03615995002000020044x · Cited by 720 · see citing works
Duan, X.-J., Zhang, W.-W., Li, X.-M., & Wang, B.-G. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2004.12.015 · Cited by 628 · see citing works
Screening methods for antibacterial and antiviral agents from higher plants
Berghe, D. A. V., & Vlietinck, A. J. (1991) · Cited by 420 · see citing works
An Assessment of the Antioxidant and Antimicrobial Activity of Six Species of Edible Irish Seaweeds
Cox, S., Abu-Ghannam, N., & Gupta, S. (2010) · PubMed · doi:10.21427/d7hc92 · Cited by 353 · see citing works
del Val, A. G., Platas, G., Basilio, Á., Cabello, A., Gorrochategui, J., Suay, I., Vicente, F., Portillo, E., del Rio, M. J., Reina, G. G.-B., et al. (2001) · International Microbiology · doi:10.1007/s101230100006 · Cited by 299 · see citing works
Antimicrobial activity of Iberian macroalgae
Salvador, N., Gómez Garreta, A., Lavelli, L., & Ribera, M. A. (2007) · Scientia Marina · doi:10.3989/scimar.2007.71n1101 · Cited by 220 · see citing works
Antimicrobial Activities of the Extracts of Marine Algae from the Coast of Urla (İzmir, Turkey)
Kızılkaya, İ. T., Çadırcı, B. H., Ünal, D., & Sukatar, A. (2006) · DergiPark (Istanbul University) · Cited by 214 · see citing works
Antibacterial activities of some marine algae from the Aegean Sea (Turkey)
Taşkın, E., Ozturk, M., Taşkın, E., & Kurt, O. (2007) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2007.000-2439 · Cited by 167 · see citing works
Antimicrobial activity of marine organisms collected off the coast of South East India
Ely, R., Tilvi, S., & Naik, C. G. (2004) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/j.jembe.2004.03.010 · Cited by 166 · see citing works
Evaluation of in vitro antibacterial property of seaweeds of southeast coast of India
M, K., hasamy, & Arunachalam, K. D. (2008) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb08.120 · Cited by 163 · see citing works
Antimicrobial potential of selected brown seaweeds from Vedalai coastal waters, Gulf of Mannar
Manivannan, K., Devi, G. K., Anantharaman, P., & Balasubramanian, T. (2011) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/s2221-1691(11)60007-5 · Cited by 143 · see citing works
Alberto, M. R., Farías, M. E., & Manca de Nadra, M. C. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0101915 · Cited by 140 · see citing works
Influence of phenolic compounds on the physiology of OEnococcus oeni from wine
Reguant, C., Bordons, A., Arola, L., & Rozés, N. (2000) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2000.01075.x · Cited by 139 · see citing works
Dietary flavonoids: effects on endothelial function and blood pressure
Hodgson, J. M., & Croft, K. D. (2006) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.2675 · Cited by 121 · see citing works
Chakraborty, K., Lipton, A. P., Raj, R., & Vijayan, K. K. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.09.019 · Cited by 115 · see citing works
Zhang, W., Duan, X., Huang, H., Zhang, Y., & Wang, B. (2006) · Journal of Applied Phycology · doi:10.1007/s10811-006-9115-x · Cited by 105 · see citing works
Screening for antibacterial activities in some marine algae from the red sea (Hurghada, Egypt)
Salem, W. M. (2011) · African Journal of Microbiology Research · doi:10.5897/ajmr11.390 · Cited by 101 · see citing works
Manilal, A., Sujith, S., Kiran, G. S., Selvin, J., Shakir, C., Gandhimathi, R., & Lipton, A. P. (2009) · Annals of Microbiology · doi:10.1007/bf03178319 · Cited by 82 · see citing works
Radical-scavenging activity of Aegean Sea marine algae
Nahas, R., Abatis, D., ANAGNOSTOPOULOU, M., Kefalas, P., Vagias, C., & Roussis, V. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.05.036 · Cited by 71 · see citing works
Moraes-de-Souza, R. A., Oldoni, T. L. C., Regitano-D’Arce, M. A. B., et al. (2008) · Ciencia y Tecnologia Alimentaria · doi:10.1080/11358120809487626 · Cited by 70 · see citing works
Antioxidant activity and phenolic composition of herbal infusions consumed in Brazil
Moraes-de-Souza, R. A., Oldoni, T. L. C., Regitano-D’Arce, M. A. B., et al. (2008) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · Cited by 57 · see citing works
Vlachos, A., Critchley, A. T., & Holy, A. T. V. (2000) · Time to knit · doi:10.1016/s0967-0653(98)82258-8 · Cited by 57 · see citing works
Yan, S. W., & Rahmat, A. B. (2010) · Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) · Cited by 49 · see citing works
Pharmacological investigation of Ocimum gratissimum in rodents
Aziba, P. I., Bass, D., & Elegbe, Y. (1999) · Phytotherapy Research · doi:10.1002/(sici)1099-1573(199908/09)13:5 · Cited by 48 · see citing works
Rao, P. P. S., Rao, P. S., & Karmarkar, S. M. (1986) · Botanica Marina · doi:10.1515/botm.1986.29.6.503 · Cited by 31 · see citing works
Screening of Marine Algae from Brazilian Northeastern Coast for Antimicrobial Activity
de Campos‐Takaki, G. M., Diu, M. B. S., Koening, M. L., et al. (1988) · Botanica Marina · doi:10.1515/botm.1988.31.5.375 · Cited by 31 · see citing works
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The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value
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Rashedy, S. H., Abd El Hafez, M. S. M., Dar, M. A., Cotas, J., & Pereira, L. (2021) · Applied Sciences · doi:10.3390/app11146290 · Cited by 135 · see citing works
Prasedya, E. S., Frediansyah, A., Martyasari, N. W. R., Ilhami, B. K., Abidin, A. S., Padmi, H., Fahrurrozi, Juanssilfero, A. B., Widyastuti, S., & Sunarwidhi, A. L. (2021) · Scientific Reports · doi:10.1038/s41598-021-95769-y · Cited by 118 · see citing works
Omar, H., Al-Judaibi, A., & El-Gendy, A. (2018) · International Journal of Pharmacology · doi:10.3923/ijp.2018.572.583 · Cited by 31 · see citing works
- Authors
- Moubayed, N. M. S., Al Houri, H. J., Al Khulaifi, M. M., & Al Farraj, D. A.
- Affiliations
- King Saud University (SA)
- Corresponding author
- Moubayed, Nadine M.S.
- Venue
- Saudi Journal of Biological Sciences
- Publisher
- Elsevier BV
- Published
- 2017-01
- Volume
- 24
- Issue
- 1
- Pages
- 162-169
- ISSN
- 1319-562X (ISSN-L)
- PMC
- PMC5198981
- OpenAlex
- W2439920887
- Cited by
- 145
- References
- 28
- Citations by year
- 2026: 8 · 2025: 9 · 2024: 10 · 2023: 20 · 2022: 20 · 2021: 27 · 2020: 22 · 2019: 15 · 2018: 8 · 2017: 6
- FWCI
- 13.91
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Saudi Journal of Biological Sciences (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- King Saud University
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
- Keywords
- seaweed, brown algae, green algae, antibacterial activity, antioxidant activity, Candida albicans, Salmonella, methicillin-resistant Staphylococcus aureus, phenolic compounds, DPPH radical scavenging, antibiotic alternatives, Red Sea, Persian Gulf
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