Stat3 Activation Is Responsible for IL-6-Dependent T Cell Proliferation Through Preventing Apoptosis: Generation and Characterization of T Cell-Specific Stat3-Deficient Mice

Cited by (584)

Items 101–200 of 584

1. Hematopoietic Stem Cells Need Two Signals to Prevent Apoptosis; Bcl-2 Can Provide One of These, Kitl/C-KIT Signaling the Other
   Jos Domen, Irving L. Weissman · 2000 · The Journal of Experimental Medicine
2. STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch
   Miho Shiratori‐Hayashi, Keisuke Koga, Hidetoshi Tozaki‐Saitoh, Yuta Kohro, Honami Toyonaga, Yamaguchi Chiharu, Ayumi Hasegawa, Takeshi Nakahara, Junichi Hachisuka, Shizuo Akira et al. · 2015 · Nature Medicine
3. STAT3 in CD4+ T helper cell differentiation and inflammatory diseases
   Charles E. Egwuagu · 2009 · Cytokine
4. IL-27 Limits IL-2 Production during Th1 Differentiation
   Alejandro V. Villarino, Jason Scott Stumhofer, Christiaan J. M. Saris, Robert A. Kastelein, Frédéric J. de Sauvage, Christopher A. Hunter · 2006 · The Journal of Immunology
5. IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis
   R. Nakamura, A. Séne, A. Santeford, A. Gdoura, S. Kubota, Nicole Zapata, R. Apte · 2015 · Nature Communications
6. Interferon α/β Promotes Cell Survival by Activating Nuclear Factor κB through Phosphatidylinositol 3-Kinase and Akt
   Chuan He Yang, Aruna Murti, Susan R. Pfeffer, Jong G. Kim, David B. Donner, Lawrence M. Pfeffer · 2001 · Journal of Biological Chemistry
7. Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation
   Shen, Yuhong, Schlessinger, Karni, Zhu, Xuejun, Meffre, Eric, Quimby, Fred, Levy, David E., Darnell, J. E. · 2004 · Molecular and Cellular Biology
8. Contribution of STAT3 to inflammatory and fibrotic diseases and prospects for its targeting for treatment
   Kasembeli, Moses M., Bharadwaj, Uddalak, Robinson, Prema, Tweardy, David J. · 2018 · International Journal of Molecular Sciences
9. A Novel Method for the Isolation of Skin Resident T Cells from Normal and Diseased Human Skin
   Rachael A. Clark, Benjamin F. Chong, Nina Mirchandani, Kei-ichi Yamanaka, Gëorge F. Murphy, Rebecca K. Dowgiert, Thomas Seth Kupper · 2006 · Journal of Investigative Dermatology
10. STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation
    Dongyao Yan, Hao‐Wei Wang, Robert L. Bowman, Johanna A. Joyce · 2016 · Cell Reports
11. IL-27 inhibits the development of regulatory T cells via STAT3
    Magdalena Huber, Vera Steinwald, Anna Guralnik, Anne Brüstle, P. Kleemann, Christine Rosenplänter, Thomas Decker, Michael D. Lohoff · 2007 · International Immunology
12. IL‐27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1
    Clemens F. Neufert, Christoph Becker, Stefan J. Wirtz, Massimo Claudio Fantini, Benno Weigmann, Peter R. Galle, Markus Friedrich Neurath · 2007 · European Journal of Immunology
13. Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 <i>Trans</i> Signaling in the Local Maintenance of Th17 Cells
    Jones, Gareth W, McLoughlin, Rachel M, Hammond, Victoria J, Parker, Clare R, Williams, John D, Malhotra, Raj, Scheller, Jürgen, Williams, Anwen S, Rose-John, Stefan, Topley, Nicholas et al. · 2010 · The Journal of Immunology
14. Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult
    Ulrich Schweizer, Jenny Margaret Gunnersen, Christoph Karch, Stefan Wiese, Bettina Holtmann, Kiyoshi Takeda, Shizuo Akira, Michael Sendtner · 2002 · The Journal of Cell Biology
15. Antiapoptotic activity ofStat5required during terminal stages of myeloid differentiation
    Matthias Kieslinger, Irina Woldman, Richard Moriggl, Johannes F.-X. Hofmann, Jean‐Christophe Marine, James N. Ihle, Hartmut Beug, Thomas Decker · 2000 · Genes & Development
16. Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases
    Shigetoshi Sano, Keith Syson Chan, John DiGiovanni · 2007 · Journal of Dermatological Science
17. Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis
    Yuko Kato, Atsushi Iwama, Yuko Tadokoro, Kazuya Shimoda, Mayu Minoguchi, Shizuo Akira, Minoru Tanaka, Atsushi Miyajima, Toshio Kitamura, Hiromitsu Nakauchi · 2005 · The Journal of Experimental Medicine
18. Psychological Stress and the Cutaneous Immune Response: Roles of the HPA Axis and the Sympathetic Nervous System in Atopic Dermatitis and Psoriasis
    Hall, Jessica M. F., Cruser, desAnges, Podawiltz, Alan, Mummert, Diana I., Jones, Harlan, Mummert, Mark E. · 2012 · Dermatology Research and Practice
19. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
    Amanda M. Nelson, Sashank Reddy, Tabetha S. Ratliff, M. Zulfiquer Hossain, Adiya S. Katseff, Amadeus S. Zhu, Emily Chang, S.G. Resnik, Carly Page, Dongwon Kim et al. · 2015 · Cell stem cell
20. Role of Leptin in Cardiovascular Diseases
    Mareike S. Poetsch, Anna Strano, Kaomei Guan · 2020 · Frontiers in Endocrinology
21. Therapeutic Activation of Signal Transducer and Activator of Transcription 3 by Interleukin-11 Ameliorates Cardiac Fibrosis After Myocardial Infarction
    Masanori Obana, Makiko Maeda, Koji Takeda, Akiko Hayama, Tomomi Mohri, Tomomi Yamashita, Yoshikazu Nakaoka, Issei Komuro, Kiyoshi Takeda, Goro Matsumiya et al. · 2010 · Circulation
22. Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways
    Chuen-Miin Leu, Fen-Hwa Wong, Chungming Chang, Shiu-Feng Kathy Huang, Cheng‐Po Hu · 2003 · Oncogene
23. Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide
    Lu Lu, Jiali Dong, Lili Wang, Qing Xia, Dan Zhang, Hye-Jin Kim, Tao Yin, Saijun Fan, Qiang Shen · 2018 · Oncogene
24. Combination of Tumor Necrosis Factor α and Interleukin‐6 Induces Mouse Osteoclast‐like Cells With Bone Resorption Activity Both In Vitro and In Vivo
    K. Yokota, Kojiro Sato, T. Miyazaki, Hideki Kitaura, H. Kayama, F. Miyoshi, Y. Araki, Y. Akiyama, K. Takeda, T. Mimura · 2014 · Arthritis & Rheumatology
25. Inactivation of Signal Transducer and Activator of Transcription 3 in Proopiomelanocortin (Pomc) Neurons Causes Decreased Pomc Expression, Mild Obesity, and Defects in Compensatory Refeeding
    Allison Wanting Xu, Linda Ste. Marie, Christopher B. Kaelin, Gregory S. Barsh · 2006 · Endocrinology
26. Endothelial Cells Require STAT3 for Protection against Endotoxin-induced Inf lammation
    Arihiro Kano, Michael J. Wolfgang, Qian Gao, Joerg J. Jacoby, Gui-Xuan Chai, William R. Hansen, Yoshiki Iwamoto, Jordan S. Pober, Richard Anthony Flavell, Xin-Yuan Fu · 2003 · The Journal of Experimental Medicine
27. In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3
    V H Sommer, Ole Jacob Clemmensen, Ole Nielsen, Mariusz A. Wasik, Paola Lovato, Christine Brender, Kirsten Eriksen, Anders Woetmann, Charlotte G. Kæstel, M H Nissen et al. · 2004 · Leukemia
28. Cutting Edge: IL-10-Independent STAT3 Activation by Toxoplasma gondii Mediates Suppression of IL-12 and TNF-α in Host Macrophages
    Barbara A. Butcher, Leesun Kim, Athanasia D. Panopoulos, Stephanie S. Watowich, Peter J. Murray, Eric Denkers · 2005 · The Journal of Immunology
29. Therapeutic potential of curcumin in digestive diseases
    Pietro Dulbecco · 2013 · World Journal of Gastroenterology
30. Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjögren’s Syndrome-like Autoimmune Disease
    Atsushi Okuma, Katsuaki Hoshino, Tomoyuki Ohba, Sawako Fukushi, Setsuya Aiba, Shizuo Akira, Masao Ono, Tsuneyasu Kaisho, Tatsushi Muta · 2013 · Immunity
31. Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity
    Kiyoshi Hirahara, Atsushi Onodera, Alejandro V. Villarino, Michael Markus Bonelli, Giuseppe Sciumè, Arian D. J. Laurence, Hong‐Wei Sun, Stephen R. Brooks, Golnaz Vahedi, Han‐Yu Shih et al. · 2015 · Immunity
32. Conditional alleles in mice: Practical considerations for tissue‐specific knockouts
    Kin Ming Kwan · 2002 · genesis
33. Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation.
    T. Miyatsuka, H. Kaneto, T. Shiraiwa, T. Matsuoka, Kaoru Yamamoto, K. Kato, Yumiko Nakamura, S. Akira, K. Takeda, Y. Kajimoto et al. · 2006 · Genes & Development
34. In Active Relapsing-Remitting Multiple Sclerosis, Effector T Cell Resistance to Adaptive T regs Involves IL-6–Mediated Signaling
    Anya Schneider, Sarah Alice Long, Karen M. Cerosaletti, Chester Ni, Peter L. Samuels, Mariko Kita, Jane Hoyt Buckner · 2013 · Science Translational Medicine
35. Signaling by STATs.
    Lionel B. Ivashkiv, Xiaoyu Hu · 2004 · Arthritis Research
36. IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21–producing B helper CD8+ T cells
    Rui Yang, April R. Masters, Karen A. Fortner, Devin Champagne, Natalia Yanguas‐Casás, Daniel J. Silberger, Casey Todd Weaver, Laura Haynes, Mercedes Rincón · 2016 · The Journal of Experimental Medicine
37. Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease
    Rebecca G. Carey, Ingrid Jurickova, Edgar T. Ballard, Erin L. Bonkowski, Xiaonan Han, Huan Xu, Lee A. Denson · 2007 · Inflammatory Bowel Diseases
38. Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
    Paul K. Ziegler, Julia Bollrath, Charles Kisali Pallangyo, Takaji Matsutani, Özge Canli, Tiago De Oliveira, Michaela A. Diamanti, Nina Müller, Jaba Gamrekelashvili, Tracy L. Putoczki et al. · 2018 · Cell
39. Cytokines and JAK–STAT Signaling
    Christian Schindler · 1999 · Experimental Cell Research
40. Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells
    Fornek, Jamie L., Tygrett, Lorraine T., Waldschmidt, Thomas J., Poli, Valeria, Rickert, Robert C., Kansas, Geoffrey S. · 2006 · Blood
41. T cell-intrinsic role of IL-6 signaling in primary and memory responses
    Simone A. Nish, Dominik Schenten, Frank Thomas Wunderlich, Scott D. Pope, Yan Gao, Namiko Hoshi, Shuang Yu, Xiting Yan, Heung Kyu Lee, Lesley Pasman et al. · 2014 · eLife
42. Role of STAT3 and PI 3-Kinase/Akt in Mediating the Survival Actions of Cytokines on Sensory Neurons
    Tonino Alonzi, Gayle Middleton, Sean L. Wyatt, Vladimir L. Buchman, Ulrich A. K. Betz, Werner Müller, Piero Musiani, Valeria Poli, Alun Milward Davies · 2001 · Molecular and Cellular Neuroscience
43. Early Activation of STAT3 Regulates Reactive Astrogliosis Induced by Diverse Forms of Neurotoxicity
    James Patrick O'Callaghan, Kimberly A. Kelly, Reyna L. VanGilder, Michael V. Sofroniew, Diane Bemis Miller · 2014 · PLoS ONE
44. Tissue-Specific Autoregulation of the stat3 Gene and Its Role in Interleukin-6-Induced Survival Signals in T Cells
    Masahiro Narimatsu, Hisoka Maeda, Shousaku Itoh, Toru Atsumi, Takuya Ohtani, Keigo Nishida, Motoyuki Itoh, Daisuke Kamimura, Sung‐Joo Park, Katsunori Mizuno et al. · 2001 · Molecular and Cellular Biology
45. STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5
    Kirsi Paukku, Olli Silvennoinen · 2004 · Cytokine & Growth Factor Reviews
46. Activation of the Signal Transducers and Activators of the Transcription 3 Pathway in Alveolar Epithelial Cells Induces Inflammation and Adenocarcinomas in Mouse Lung
    Yuan Li, Hong Du, Yulin Qin, Jennifer Roberts, Oscar W. Cummings, Cong Yan · 2007 · Cancer Research
47. The model of cytokine release syndrome in CAR T-cell treatment for B-cell non-Hodgkin lymphoma
    Jianshu Wei, Yang Liu, Chunmeng Wang, Yajing Zhang, Chuan Tong, Guanghai Dai, Wei Wang, John E. J. Rasko, Jan Joseph Melenhorst, Wenbin Qian et al. · 2020 · Signal Transduction and Targeted Therapy
48. CD8+ T Cells in Facioscapulohumeral Muscular Dystrophy Patients with Inflammatory Features at Muscle MRI
    Giovanni Frisullo, Roberto Frusciante, Viviana Nociti, Giorgio A. Tasca, Rosaria Renna, Raffaele Iorio, Agata Katia Patanella, Elisabetta Iannaccone, Alessandro Marti, Monica Rossi et al. · 2010 · Journal of Clinical Immunology
49. Essential Role of STAT3 in Body Weight and Glucose Homeostasis
    Yunxia Cui, Lu Huang, Florent Elefteriou, Guoqing Yang, John Michael Shelton, Jerald E. Giles, Orhan K. Öz, Tiffany Pourbahrami, Christopher Y. Lu, James A. Richardson et al. · 2003 · Molecular and Cellular Biology
50. Notch-Hes1 pathway is required for the development of IL-17–producing γδ T cells
    Kensuke Shibata, Hisakata Yamada, Tetsuya Sato, Takashi Dejima, Masataka Nakamura, Tomokatsu Ikawa, Hiromitsu Hara, Sho Yamasaki, Ryoichiro Kageyama, Yoichiro Iwakura et al. · 2011 · Blood
51. Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation
    Garima Garg, Andreas Muschaweckh, Helena Domínguez Moreno, Ajithkumar Vasanthakumar, Stefan Floess, Gildas Lepennetier, Rupert Oellinger, Yifan Zhan, Tommy Regen, Michael Hiltensperger et al. · 2019 · Cell Reports
52. Inhibition of IL-6 and IL-10 Signaling and Stat Activation by Inflammatory and Stress Pathways
    Simi T. Ahmed, Lionel B. Ivashkiv · 2000 · The Journal of Immunology
53. Interleukin-13 drives metabolic conditioning of muscle to endurance exercise
    Knudsen, Nelson H., Stanya, Kristopher J., Hyde, Alexander L., Chalom, Mayer M., Alexander, Ryan K., Liou, Yae-Huei, Starost, Kyle A., Gangl, Matthew R., Jacobi, David, Liu, Sihao et al. · 2020 · Science
54. Specific ablation of Stat3β distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock
    Yoo, Joo-Yeon, Huso, David L., Nathans, Daniel, Desiderio, Stephen · 2002 · Cell
55. Signal transducer and activator of transcription 3 activation is required for Asp816 mutant c-Kit–mediated cytokine-independent survival and proliferation in human leukemia cells
    Zhi-Qiang Ning, Jin Li, Robert John Arceci · 2001 · Blood
56. Airway Epithelial STAT3 Is Required for Allergic Inflammation in a Murine Model of Asthma
    Marina Simeone, Mariano Severgnini, Powen Tu, Robert Homer, Thomas J. Mariani, Lauren E. Cohn, Amy R. Simon · 2007 · The Journal of Immunology
57. Bone morphogenetic protein-2 induces apoptosis in human myeloma cells with modulation of STAT3
    Chiharu Kawamura, Masahiro Kizaki, Kenji Yamato, Hideo Uchida, Yumi Fukuchi, Yutaka Hattori, Takeyoshi Koseki, Tatsuji Nishihara, Yasuo Ikeda · 2000 · Blood
58. A cre recombinase transgene with mosaic, widespread tamoxifen‐inducible action
    Caiying Guo, Wen‐Yi Yang, Corrinne G. Lobe · 2002 · genesis
59. IL-27 Suppresses CD28-Medicated IL-2 Production through Suppressor of Cytokine Signaling 3
    Toshiyuki Owaki, Masayuki Asakawa, Sadahiro Kamiya, Kiyoshi Takeda, Fumio Fukai, Junichiro Mizuguchi, Takayuki Yoshimoto · 2006 · The Journal of Immunology
60. Janus kinase 3 (Jak3) is essential for common cytokine receptor γ chain (γc)-dependent signaling: comparative analysis of γc, Jak3, and γc and Jak3 double-deficient mice
    Kotaro Suzuki, Hiroshi Nakajima, Yasushi Saito, Takashi Saito, Warren J. Leonard, Itsuo Iwamoto · 2000 · International Immunology
61. STAT3 negatively regulates thyroid tumorigenesis
    Joana Pinto Couto, Laura Daly, Ana Paula de Almeida, Jeffrey A. Knauf, James A. Fagin, Manuel A. Sobrinho-Simões, Jorge Pereira Lima, Valdemar Máximo, Paula Soares, David C. Lyden et al. · 2012 · Proceedings of the National Academy of Sciences
62. Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
    Bola S. Hanna, Laura Llaó Cid, Murat Iskar, Philipp M. Roessner, Lara C. Klett, John Wong, Yashna Paul, Nikolaos Ioannou, Selcen Öztürk, Norman L. Mack et al. · 2021 · Immunity
63. Role of STAT3 in inflammatory bowel disease
    Ken Sugimoto · 2008 · World Journal of Gastroenterology
64. Crucial role of the interleukin‐6/interleukin‐17 cytokine axis in the induction of arthritis by glucose‐6‐phosphate isomerase
    Keiichi Iwanami, Isao Matsumoto, Yoko Tanaka-Watanabe, Asuka Inoue, Masahiko Mihara, Yoshiyuki Ohsugi, Mizuko Mamura, Daisuke Goto, Satoshi Ito, Akito Tsutsumi et al. · 2008 · Arthritis & Rheumatism
65. Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries
    Sun, Daniel, Moore, Sara, Jakobs, Tatjana C. · 2017 · Journal of Experimental Medicine
66. STAT signaling in mammary gland differentiation, cell survival and tumorigenesis
    Svasti Haricharan, Yi Li · 2013 · Molecular and Cellular Endocrinology
67. Cytokines and STAT Signaling
    Christian Schindler, Inga Strehlow · 1999 · Advances in pharmacology
68. Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex
    Takeshi Yoshimatsu, Daichi Kawaguchi, Koji Oishi, Kiyoshi Takeda, Shizuo Akira, Norihisa Masuyama, Yukiko Gotoh · 2006 · Development
69. Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling
    Hiroki Suemoto, Yasuteru Muragaki, Katsuhiro Nishioka, Misako Sato, Akira Ooshima, Shunji Itoh, Ikuji Hatamura, Michitaka Ozaki, Attila Braun, Erika Gustafsson et al. · 2007 · Developmental Biology
70. Deletion of Stat3 Blocks Mammary Gland Involution and Extends Functional Competence of the Secretory Epithelium in the Absence of Lactogenic Stimuli
    Robin C. Humphreys, Brian Bierie, Ling Zhao, Regina Raz, David E. Levy, Lothar G. Hennighausen · 2002 · Endocrinology
71. Interleukin-6 Signal Transduction and Lymphocyte Function
    Friedemann Horn, Christian Henze, Katja Heidrich · 2000 · Immunobiology
72. Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning
    SMITH, R, SULEMAN, N, LACERDA, L, OPIE, L, AKIRA, S, CHIEN, K, SACK, M · 2004 · Cardiovascular Research
73. Stat-3 is required for pulmonary homeostasis during hyperoxia
    Hokuto, Isamu, Ikegami, Machiko, Yoshida, Mitsuhiro, Takeda, Kiyoshi, Akira, Shizuo, Perl, Anne-Karina T., Hull, William M., Wert, Susan E., Whitsett, Jeffrey A. · 2004 · Journal of Clinical Investigation
74. TAB2 Is Essential for Prevention of Apoptosis in Fetal Liver but Not for Interleukin-1 Signaling
    Hideki Sanjo, Kiyoshi Takeda, Tohru Tsujimura, Jun Ninomiya‐Tsuji, Kunihiro Matsumoto, Shizuo Akira · 2003 · Molecular and Cellular Biology
75. Neuronal STAT3 activation is essential for CNTF- and inflammatory stimulation-induced CNS axon regeneration
    Marco Leibinger, Anastasia Andreadaki, H Diekmann, Dietmar Fischer · 2013 · Cell Death and Disease
76. Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival
    David Duval, Béatrice Reinhardt, Claude Kédinger, Hélène Bœuf · 2000 · The FASEB Journal
77. STAT3 Activation Regulates Growth, Inflammation, and Vascularization in a Mouse Model of Gastric Tumorigenesis
    Louise M. Judd, Karin Bredin, Anastasia Kalantzis, Brendan John Jenkins, Matthias Ernst, Andrew S. Giraud · 2006 · Gastroenterology
78. Pathogenesis of myeloproliferative neoplasms
    Radek C. Skoda, Adrian Duek, Jean Grisouard · 2015 · Experimental Hematology
79. Signal transducer and activator of transcription‐3 ( Stat3 ) plays a critical role in implantation via progesterone receptor in uterus
    Jae Hee Lee, Tae Hoon Kim, Seo Jin Oh, Jung‐Yoon Yoo, Shizuo Akira, Bon Jeong Ku, John P. Lydon, Jae‐Wook Jeong · 2013 · The FASEB Journal
80. STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection
    Qinli Sun, Xiaohong Zhao, Ruifeng Li, Dingfeng Liu, Birui Pan, Bowen Xie, Xinxin Chi, Dongli Cai, Peng Wei, Wei Xu et al. · 2023 · The Journal of Experimental Medicine
81. New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation
    Lai Wei, Arian D. J. Laurence, John J. O’Shea · 2008 · Seminars in Cell and Developmental Biology
82. Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity
    Benjamin Knier, Michael Hiltensperger, Christopher Sie, Lilian Aly, Gildas Lepennetier, Thomas Engleitner, Garima Garg, Andreas Muschaweckh, Meike Mitsdoerffer, Uwe Koedel et al. · 2018 · Nature Immunology
83. LIF signaling in stem cells and development
    Kento Onishi, Peter W. Zandstra · 2015 · Development
84. Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist
    Lyudmila G. Burdelya, Craig M. Brackett, Bojidar Kojouharov, Ilya I. Gitlin, Katerina I. Leonova, Anatoli S. Gleiberman, Semra Aygun‐Sunar, Jean M. Veith, Christopher Johnson, Gary J. Haderski et al. · 2013 · Proceedings of the National Academy of Sciences
85. The activity of JAK-STAT pathways in rheumatoid arthritis: constitutive activation of STAT3 correlates with interleukin 6 levels
    Pia Isomäki, Ilkka Junttila, Krista-Liisa Vidqvist, Markku M. Korpela, Olli Silvennoinen · 2014 · Lara D. Veeken
86. STAT3 Regulates Uterine Epithelial Remodeling and Epithelial-Stromal Crosstalk During Implantation
    Sandeep Pawar, Elina Starosvetsky, Grant D. Orvis, Richard R. Behringer, Indrani C. Bagchi, Milan K. Bagchi · 2013 · Molecular Endocrinology
87. Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells
    Hanako Daino, Itaru Matsumura, Koji Takada, Junko Odajima, Hirokazu Tanaka, Shuji Ueda, Hirohiko Shibayama, Hirokazu Ikeda, Masahiko Hibi, Takashi Machii et al. · 2000 · Blood
88. STAT3 Protein Promotes T-cell Survival and Inhibits Interleukin-2 Production through Up-regulation of Class O Forkhead Transcription Factors
    Hyun‐Mee Oh, Cheng‐Rong Yu, Nady Golestaneh, Ahjoku Amadi‐Obi, Yun Sang Lee, Amarachi C. Eseonu, Rashid M. Mahdi, Charles E. Egwuagu · 2011 · Journal of Biological Chemistry
89. Signal Transducers and Activators of Transcription 3 Signaling Pathway
    Alessandro Musso, Patrizia Dentelli, Alessandra Carlino, Luigi Chiusa, Alessandro Repici, Andreas Sturm, Claudio Fiocchi, Mario Rizzetto, Luigi Pegoraro, Carla Sategna-Guidetti et al. · 2005 · Inflammatory Bowel Diseases
90. A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver
    Inverso, Donato, Shi, Jingjing, Lee, Ki Hong, Jakab, Moritz, Ben-Moshe, Shani, Kulkarni, Shubhada R., Schneider, Martin, Wang, Guanxiong, Komeili, Marziyeh, Vélez, Paula Argos et al. · 2021 · Developmental Cell
91. Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development
    Jacqueline Bromberg · 2000 · Breast Cancer Research
92. Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice
    Tomokazu Matsuda, Yoshiaki Kido, Shun‐ichiro Asahara, Tsuneyasu Kaisho, Takashi Tanaka, Naoko Hashimoto, Yutaka Shigeyama, Akihiko Takeda, Tae Inoue, Yuki Shibutani et al. · 2009 · Journal of Clinical Investigation
93. Specific Physiological Roles for Signal Transducer and Activator of Transcription 3 in Leptin Receptor-Expressing Neurons
    Merisa L. Piper, Elizabeth K. Unger, Martin Grosvenor Myers, Allison Wanting Xu · 2007 · Molecular Endocrinology
94. Leptin Suppresses the Rewarding Effects of Running via STAT3 Signaling in Dopamine Neurons
    Maria F. Fernandes, Dominique Matthys, Cécile Hryhorczuk, Sandeep Sharma, Shabana Mogra, Thierry Alquier, Stephanie E. Fulton · 2015 · Cell Metabolism
95. IL-6 Plays a Unique Role in Initiating c-Maf Expression during Early Stage of CD4 T Cell Activation
    Yu Yang, Jordi Ochando, Adam Charles Yopp, Jonathan S. Bromberg, Yaozhong Ding · 2005 · The Journal of Immunology
96. Importance of STAT3 signalling in cancer, metastasis and therapeutic interventions
    Mohamed El‐Tanani, Arwa Omar Al Khatib, Safwan Aladwan, Ahmed Abuelhana, Paul A. McCarron, Murtaza M. Tambuwala · 2022 · Cellular Signalling
97. Stat3 in Thymic Epithelial Cells Is Essential for Postnatal Maintenance of Thymic Architecture and Thymocyte Survival
    Shigetoshi Sano, Yousuke Takahama, Takehiko Sugawara, Hiroshi Kosaka, Satoshi Itami, Kunihiko Yoshikawa, Jun‐ichi Miyazaki, Willem van Ewijk, Junji Takeda · 2001 · Immunity
98. Leptin–cytokine crosstalk in breast cancer
    G W Newman, Ruben Rene Gonzalez-Perez · 2013 · Molecular and Cellular Endocrinology
99. Epidermal Growth Factor Receptor–Mediated Stat3 Signaling Blocks Apoptosis in Head and Neck Cancer
    Jennifer Rubin Grandis, Qing Zeng, Stephanie D. Drenning · 2000 · The Laryngoscope
100. Interleukin‐6 is a direct mediator of T cell migration
     Manuela Weißenbach, Thomas Clahsen, Christian Weber, D. Spitzer, Dagmar Wirth, Dietmar Vestweber, Peter Claus Heinrich, Fred Schaper · 2004 · European Journal of Immunology