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Cited by 304

The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.

CLINICAL ASPECTS OF UNCOMPLICATED AND SEVERE MALARIA

Open access
Bartoloni, Alessandro, Zammarchi, Lorenzo·2012·Mediterranean Journal of Hematology and Infectious Diseases
DOI 10.4084/mjhid.2012.026
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Abstract

The first symptoms of malaria, common to all the different malaria species, are nonspecific and mimic a flu-like syndrome. Although fever represents the cardinal feature, clinical findings in malaria are extremely diverse and may range in severity from mild headache to serious complications leading to death, particularly in falciparum malaria. As the progression to these complications can be rapid, any malaria patient must be assessed and treated rapidly, and frequent observations are needed to look for early signs of systemic complications.In fact, severe malaria is a life threatening but treatable disease. The protean and nonspecific clinical findings occurring in malaria (fever, malaise, headache, myalgias, jaundice and sometimes gastrointestinal symptoms of nausea, vomiting and diarrhoea) may lead physicians who see malaria infrequently to a wrong diagnosis, such as influenza (particularly during the seasonal epidemic flu), dengue, gastroenteritis, typhoid fever, viral hepatitis, encephalitis. Physicians should be aware that malaria is not a clinical diagnosis but must be diagnosed, or excluded, by performing microscopic examination of blood films. Prompt diagnosis and appropriate treatment are then crucial to prevent morbidity and fatal outcomes. Although Plasmodium falciparum malaria is the major cause of severe malaria and death, increasing evidence has recently emerged that Plasmodium vivax and Plasmodium knowlesi can also be severe and even fatal.

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Metadata

Authors
Bartoloni, A., & Zammarchi, L.
Venue
Mediterranean Journal of Hematology and Infectious Diseases
Publisher
Hematology Section, Dept. of Radiological Science and Hematology, Catholic University, Rome, Italy
Published
2012-05-04
Volume
4
Issue
1
Pages
e2012026
ISSN
2035-3006 (ISSN-L)
DOI
10.4084/mjhid.2012.026
OpenAlex
W2135802236
Cited by
304
References
66
FWCI
7.23
Type
journal article
Language
en
Open access
gold

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