The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Activity of mesenchymal stem cells in therapies for chronic skin wound healing
Open accessAbstract
Chronic or non-healing skin wounds present an ongoing challenge in advanced wound care, particularly as the number of patients increases while technology aimed at stimulating wound healing in these cases remains inefficient. Mesenchymal stem cells (MSCs) have proved to be an attractive cell type for various cell therapies due to their ability to differentiate into various cell lineages, multiple donor tissue types, and relative resilience in ex-vivo expansion, as well as immunomodulatory effects during transplants. More recently, these cells have been targeted for use in strategies to improve chronic wound healing in patients with diabetic ulcers or other stasis wounds. Here, we outline several mechanisms by which MSCs can improve healing outcomes in these cases, including reducing tissue inflammation, inducing angiogenesis in the wound bed, and reducing scarring following the repair process. Approaches to extend MSC life span in implant sites are also examined.
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Burn injury: Challenges and advances in burn wound healing, infection, pain and scarring
Wang, Y., Beekman, J., Hew, J., Jackson, S., Issler-Fisher, A. C., Parungao, R., Lajevardi, S. S., Li, Z., & Maitz, P. K. M. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.09.018 · Cited by 696
Macrophages as a therapeutic target to promote diabetic wound healing
Sharifiaghdam, M., Shaabani, E., Faridi-Majidi, R., De Smedt, S. C., Braeckmans, K., & Fraire, J. C. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2022.07.016 · Cited by 573
Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies
Nourian Dehkordi, A., Mirahmadi Babaheydari, F., Chehelgerdi, M., & Raeisi Dehkordi, S. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1212-2 · Cited by 533
A Cooperative Copper Metal–Organic Framework‐Hydrogel System Improves Wound Healing in Diabetes
Xiao, J., Chen, S., Yi, J., Zhang, H. F., & Ameer, G. A. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201604872 · Cited by 428
The Role of MSC in Wound Healing, Scarring and Regeneration
Guillamat-Prats, R. (2021) · Cells · doi:10.3390/cells10071729 · Cited by 393
Metadata
- Authors
- Nuschke, A.
- Venue
- Organogenesis
- Publisher
- Informa UK Limited
- Published
- 2013-12-10
- Volume
- 10
- Issue
- 1
- Pages
- 29-37
- ISSN
- 1547-6278 (ISSN-L)
- 1555-8592
- OpenAlex
- W2001890367
- Cited by
- 169
- References
- 13
- FWCI
- 11.43
- Type
- journal article
- Language
- en
- Open access
- bronze
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