The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Hydrogel scaffolds for tissue engineering: Progress and challenges
Open accessAbstract
Designing of biologically active scaffolds with optimal characteristics is one of the key factors for successful tissue engineering. Recently, hydrogels have received a considerable interest as leading candidates for engineered tissue scaffolds due to their unique compositional and structural similarities to the natural extracellular matrix, in addition to their desirable framework for cellular proliferation and survival. More recently, the ability to control the shape, porosity, surface morphology, and size of hydrogel scaffolds has created new opportunities to overcome various challenges in tissue engineering such as vascularization, tissue architecture and simultaneous seeding of multiple cells. This review provides an overview of the different types of hydrogels, the approaches that can be used to fabricate hydrogel matrices with specific features and the recent applications of hydrogels in tissue engineering. Special attention was given to the various design considerations for an efficient hydrogel scaffold in tissue engineering. Also, the challenges associated with the use of hydrogel scaffolds were described.
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Cites
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Cited by
Is it time to start transitioning from 2D to 3D cell culture?
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Metadata
- Authors
- El-Sherbiny, I. M., & Yacoub, M. H.
- Venue
- Global Cardiology Science and Practice
- Published
- 2013-09
- Volume
- 2013
- Issue
- 3
- Pages
- 38
- ISSN
- 2305-7823 (ISSN-L)
- OpenAlex
- W2126956733
- Cited by
- 1,062
- References
- 12
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- diamond
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.