Cited by 89Sexual function and dysfunction studiesHormonal and reproductive studiesUrological Disorders and Treatments

Risk factors for erectile dysfunction in a cohort of 108,477 Australian men

Weber, Marianne F, Smith, David P, OˈConnell, Dianne L, Patel, Manish I, Souza, Paul L, Sitas, Freddy, Banks, Emily·2013·Medical Journal of Australia

Abstract

OBJECTIVES: To quantify relationships between erectile dysfunction (ED), ageing and health and lifestyle factors for men aged 45 years and older. DESIGN: Cross-sectional, population-based study seeking data on health, sociodemographic and lifestyle factors by questionnaire (the 45 and Up Study). PARTICIPANTS AND SETTING: 108 477 men aged 45 years or older, living in New South Wales, and recruited into the 45 and Up Study between 10 January 2006 and 17 February 2010. MAIN OUTCOME MEASURES: Self-reported ED. RESULTS: In the 101 674 men reporting no prior diagnosis of prostate cancer, 39.31% (95% CI, 39.01%-39.61%) had no ED, 25.14% (95% CI, 24.87%-25.40%) had mild ED (ie, experienced ED sometimes), 18.79% (95% CI, 18.55%-19.03%) had moderate (ie, usually experienced) ED and 16.77% (95% CI, 16.55%-17.00%) had complete ED. After adjusting for sociodemographic characteristics, the odds of moderate/complete ED increased by 11.30% (OR, 1.11; 95% CI, 1.11-1.12) each year from the age of 45 years. Overall, the risk of moderate/complete ED was higher among men with low socioeconomic status, high body mass index, those who were sedentary, current smokers and those with diseases including diabetes, heart disease, and depression/anxiety, compared with men without these risk factors. Moderate alcohol consumption was associated with a significantly reduced risk of ED in men aged 45-54 years, but not in older men. Almost all men aged 75 or older reported moderate/severe ED; however, increased physical activity was associated with a lower odds of ED in this group. CONCLUSIONS: In a large population-based cross-sectional study, ED increased considerably with age. There are a range of potentially modifiable risk factors for ED, including smoking, low physical activity, and high body mass index.

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Crossref · 10.5694/mja12.11548

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Authors
Weber, M. F., Smith, D. P., OˈConnell, D. L., Patel, M. I., Souza, P. L., Sitas, F., & Banks, E.
Affiliations
  • Cancer Council NSW (AU)
  • Cancer Research Division, Cancer Council NSW, Sydney, NSW.
  • The University of Sydney (AU)
  • Western Sydney University (AU)
  • Australian National University (AU)
Corresponding author
Weber, Marianne F
Venue
Medical Journal of Australia
Publisher
AMPCo
Published
2013-05-06
Volume
199
Issue
2
Pages
107-111
ISSN
  • 0025-729X (ISSN-L)
  • 1326-5377
OpenAlex
W2076709928
Cited by
89
References
24
Citations by year
2026: 4 · 2025: 4 · 2024: 8 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 8 · 2019: 8 · 2018: 10 · 2017: 3 · 2016: 10 · 2015: 9 · 2014: 5 · 2013: 2
FWCI
6.13
Type
journal article
Language
en
Open access
closed
Locations
  • The Medical Journal of Australia (publishedVersion)
  • PubMed (publishedVersion)
  • ANU Open Research (Australian National University) (submittedVersion)
  • The Sydney eScholarship Repository (The University of Sydney) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Urology › Urological Disorders and Treatments
Keywords
erectile dysfunction, risk factors, aging, socioeconomic status, body mass index, physical activity, sedentary lifestyle, smoking, alcohol consumption, diabetes mellitus, heart disease, anxiety and depression, 45 and Up Study
MeSH terms
Age Factors, Aged, Aged, 80 and over, Cross-Sectional Studies, Health Surveys, Humans, Erectile Dysfunction, Life Style, Male, Middle Aged, New South Wales, Risk Factors, Socioeconomic Factors, Cohort Studies, Logistic Models, Odds Ratio, Self Report

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