Resveratrol: A Promising Antiaging Agent for Cosmetic Skin Treatments
Open accessAbstract
Nowadays, resveratrol, a polyphenolic phytoalexin is increasingly included in the formulas of cosmetic products and dermatology as an active ingredient, as a consequence of the well-known health beneficial properties, namely antioxidant, anti-inflammatory, anti-viral and anti-bacterial effects. This important compound can be biosynthesized naturally by plants or by industrial synthetic processes. Apart from its anti-inflammatory and antioxidant effects, a broad spectrum of effects has been attributed to the use of this compound such as anti-aging, skin-whitening, anti-angiogenic, collagen I and III stimulation (in fibroblasts) and estrogen-like effects, as well as the ability to protect cells against hydrogen peroxide-induced oxidative stress and UV-irradiation-mediated cell death. In cosmetology and dermatology has been popular because of its ability to penetrate the skin barrier and its anti-aging activity. In fact, resveratrol as an important impact on the regulation of inflammation and, as consequence, repair-related processes in skin. Furthermore, when administered either topically or orally has been proven to be safe and also to overcome the skin barrier. This review will focus in its potential application on melasma treatment and in photo-aging. Resveratrol chemistry, pharmacology, mechanism of action and evidence of its efficacy as photo skin aging protector and its potential use in melasma is discussed.
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Fidalgo et al. 27 rely heavily on existing research studies and do not provide any new data of their own.
“The authors rely heavily on existing research studies and do not provide any new data of their own.”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [27]
The Fidalgo et al. 27 article likely falls under Level V evidence according to the Oxford Centre for Evidence-Based Medicine.
“The level of evidence for this article would likely fall under Level V according to the Oxford Centre for Evidence‐Based Medicine”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [27]
The paper’s “Clinical evidence of resveratrol uses in cosmetics” section summarizes studies, but does not assign itself an evidence level. A search for “Level V” and the Oxford Centre for Evidence-Based Medicine found no such classification in our copy; the sentence appears to be the citing authors’ own assessment. (LLM, conf=0.76)
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Cited by
Sorted by citations
Cosmeceuticals in photoaging: A review.
Chan, L. K. W., Lee, K. W. A., Lee, C. H., Lam, K. W. P., Lee, K. F. V., Wu, R., Wan, J., Shivananjappa, S., Sky, W. T. H., Choi, H., et al. (2024) · Skin Research and Technology · doi:10.1111/srt.13730 · Cited by 23 · see citing works
- Authors
- Fidalgo, J., Novo Barros, A., & Casas, A.
- Venue
- Resveratrol - Recent Advances, Application, and Therapeutic Potential
- Publisher
- IntechOpen
- Published
- 2024-07-10
- OpenAlex
- W4307066500
- Cited by
- 3
- References
- 62
- Citations by year
- 2025: 1 · 2024: 2
- FWCI
- 8.39
- Type
- book chapter
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- IntechOpen eBooks (publishedVersion, cc-by)
- IntechOpen (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Sirtuins and Resveratrol in Medicine
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- resveratrol, anti-aging, cosmetic skin care, melasma, photoaging, antioxidant activity, anti-inflammatory activity, skin barrier penetration, UV-induced cell death, oxidative stress, collagen stimulation, skin lightening, phytoalexins
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