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Plasma Phospholipid Long-Chain ω-3 Fatty Acids and Total and Cause-Specific Mortality in Older Adults: A Cohort Study
Open accessAbstract
BACKGROUND: Long-chain ω-3 polyunsaturated fatty acids (ω3-PUFAs), including eicosapentaenoic acid (EPA) (20:5ω-3), docosapentaenoic acid (DPA) (22:5ω-3), and docosahexaenoic acid (DHA) (22:6ω-3), have been shown to reduce cardiovascular risk, but effects on cause-specific and total mortality and potential dose-responses remain controversial. Most observational studies have assessed self-reported dietary intake and most randomized trials have tested effects of adding supplements to dietary intake and evaluated secondary prevention, thus limiting inference for dietary ω3-PUFAs or primary prevention. OBJECTIVE: To investigate associations of plasma phospholipid EPA, DPA, DHA, and total ω3-PUFA levels with total and cause-specific mortality among healthy older adults not receiving supplements. DESIGN: Prospective cohort study. SETTING: 4 U.S. communities. PARTICIPANTS: 2692 U.S. adults aged 74 years (±5 years) without prevalent coronary heart disease (CHD), stroke, or heart failure at baseline. MEASUREMENTS: Phospholipid fatty acid levels and cardiovascular risk factors were measured in 1992. Relationships with total and cause-specific mortality and incident fatal or nonfatal CHD and stroke through 2008 were assessed. RESULTS: During 30 829 person-years, 1625 deaths (including 570 cardiovascular deaths), 359 fatal and 371 nonfatal CHD events, and 130 fatal and 276 nonfatal strokes occurred. After adjustment, higher plasma levels of ω3-PUFA biomarkers were associated with lower total mortality, with extreme-quintile hazard ratios of 0.83 for EPA (95% CI, 0.71 to 0.98; P for trend = 0.005), 0.77 for DPA (CI, 0.66 to 0.90; P for trend = 0.008), 0.80 for DHA (CI, 0.67 to 0.94; P for trend = 0.006), and 0.73 for total ω3-PUFAs (CI, 0.61 to 0.86; P for trend < 0.001). Lower risk was largely attributable to fewer cardiovascular than noncardiovascular deaths. Individuals in the highest quintile of phospholipid ω3-PUFA level lived an average of 2.22 more years (CI, 0.75 to 3.13 years) after age 65 years than did those in the lowest quintile. LIMITATION: Temporal changes in fatty acid levels and misclassification of causes of death may have resulted in underestimated associations, and unmeasured or imperfectly measured covariates may have caused residual confounding. CONCLUSION: Higher circulating individual and total ω3-PUFA levels are associated with lower total mortality, especially CHD death, in older adults. PRIMARY FUNDING SOURCE: National Institutes of Health.
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In the citing paper
“circulating concentrations of eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) inversely correlate with cardiovascular risk. 3,4”
From Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk (2020) · cites this paper as [3]
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In the citing paper
“The potential value of omega-3 fatty acids was supported by epidemiological studies demonstrating aninverserelationship between circulating concentrations of omega-3fattyacidsandcardiovascularrisk. 3,4”
From Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk (2020) · cites this paper as [3]
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In the citing paper
“than corresponding values from population studies in the USA (0.5 % EPA and 2.9 % DHA) 35 , suggesting higher background consumption of n-3 PUFA in our Norwegian study population.”
From Effects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction (2021) · cites this paper as [35]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“It is also worth noting that the baseline median levels in our material (2.5 % EPA and 5.6 % DHA) are notably higher than corresponding values from population studies in the USA (0.5 % EPA and 2.9 % DHA) 35 , suggesting higher background consumption of n-3 PUFA in”
From Effects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction (2021) · cites this paper as [35]
Experimental — accuracy not yet measuredIn the citing paper
“Biomarker levels of these fatty acids are only moderately interrelated (eg, r = 0.43,0.51, and 0.13 for EPA and DHA, EPA and DPA, and DPA and DHA, respectively).41”
From ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies (2016) · cites this paper as [41]
In the citing paper
“Observational evidence supports the recommendation that the intake of fish (at least twice a week) and long chain n-3 fatty acids supplements at low dosage may reduce the risk of CV death and stroke in primary prevention, but have no major effects on plasma lipoprotein metabolism. 183”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [183]
In the citing paper
“Not enough data are available to make a recommendation regarding the optimal n-3:n-6 fatty acid ratio.182,183”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [183]
In the citing paper
“Observational evidence supports the recommendation that the intake of fish (at least twice a week) and long chain n-3 fatty acids supplements at low dosage may reduce the risk of CV death and stroke in primary prevention, but have no major effects on plasma lipoprotein metabolism.183”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [183]
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Citations
Cites
Bootstrap methods: another look at the jackknife
Efron, B. (1979) · The Annals of Statistics · doi:10.1214/aos/1176344552 · Cited by 17,602
Cox, D. R., & Oakes, D. (2018) · Chapman & Hall/CRC eBooks · doi:10.1201/9781315137438 · Cited by 6,269
Food, nutrition, physical activity, and the prevention of cancer: a global perspective
Marmot, M. G., Atinmo, T., Byers, T., Chen, J., Hirohata, T., Jackson, A., James, W., Kolonel, L. N., Kumanyika, S., Leitzmann, C., et al. (2008) · Choice Reviews Online · doi:10.5860/choice.45-5024 · Cited by 5,368
Breslow, N. E., Cox, D. R., & Oakes, D. (1985) · Biometrics · doi:10.2307/2530888 · Cited by 4,381
The Cardiovascular Health Study: design and rationale.
Fried, L. P., Borhani, N. O., Enright, P., Furberg, C. D., Gardin, J. M., Kronmal, R. A., Kuller, L. H., Manolio, T. A., Mittelmark, M. B., Newman, A., et al. (1991) · Annals of Epidemiology · doi:10.1016/1047-2797(91)90005-w · Cited by 3,652
Flexible regression models with cubic splines
Durrleman, S., & Simon, R. M. (1989) · Statistics in Medicine · doi:10.1002/sim.4780080504 · Cited by 2,722
Yokoyama, M., Origasa, H., Matsuzaki, M., Matsuzawa, Y., Saito, Y., Ishikawa, Y., Oikawa, S., Sasaki, J., Hishida, H., Itakura, H., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60527-3 · Cited by 2,516
Fish Intake, Contaminants, and Human Health: Evaluating the Risks and the Benefits
Mozaffarian, D., & Rimm, E. B. (2006) · JAMA · doi:10.1001/jama.296.15.1885 · Cited by 1,966
Self-citation
Research works printed but not linked: 2
- Breslow NE, 1972, J R Stat Soc Series B Stat Methodol, 34, 216
- Fotuhi M, 2009, Nat Clin Pract Neurol, 5, 140
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Harris, W. S., Masson, S., Barlera, S., Milani, V., Pileggi, S., Franzosi, M. G., Marchioli, R., Tognoni, G., Tavazzi, L., & Latini, R. (2016) · Nutrition Research · doi:10.1016/j.nutres.2016.06.012 · Cited by 38
Tian, Y., Katsuki, A., Romanazzi, D., Miller, M. R., Adams, S. L., Miyashita, K., & Hosokawa, M. (2017) · Journal of Oleo Science · doi:10.5650/jos.ess17111 · Cited by 38
Fretts, A. M., Mozaffarian, D., Siscovick, D. S., King, I. B., McKnight, B., Psaty, B. M., Rimm, E. B., Sitlani, C. M., Sacks, F. M., Song, X., et al. (2015) · Journal of Nutrition · doi:10.3945/jn.115.222117 · Cited by 37
Self-citationStanton, A. V., James, K., Brennan, M. M., O’Donovan, F., Buskandar, F., Shortall, K., El-Sayed, T., Kennedy, J., Hayes, H., Fahey, A. G., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-71801-5 · Cited by 37
Chilton, F. H., Manichaikul, A. W., Yang, C., O’Connor, T. D., Johnstone, L. M., Blomquist, S. A., Schembre, S. M., Sergeant, S., Zec, M. M., Tsai, M. Y., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.808054 · Cited by 43
Harris, K., Oshima, M., Sattar, N. A., Würtz, P., Jun, M., Welsh, P. I., Hamet, P., Harrap, S. B., Poulter, N. R., Chalmers, J. P., et al. (2020) · Diabetologia · doi:10.1007/s00125-020-05162-z · Cited by 33
McBurney, M. I., Tintle, N., Vasan, R. S., Sala‐Vila, A., & Harris, W. S. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab195 · Cited by 34
Recommended Intake of Fish and Fish Oils Worldwide
Richter, C. K., Skulas‐Ray, A. C., & Kris‐Etherton, P. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802844-5.00003-8 · Cited by 35
History and future of omega-3 fatty acids in cardiovascular disease
Sperling, L. S., & Nelson, J. R. (2016) · Current Medical Research and Opinion · doi:10.1185/03007995.2015.1120190 · Cited by 34
KONES, R. J., Howell, S. L., & Rumana, U. (2017) · Medical Principles and Practice · doi:10.1159/000485837 · Cited by 35
Strategies to improve bioavailability of omega-3 fatty acids from ethyl ester concentrates
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Monoacylglycerol Form of Omega-3s Improves Its Bioavailability in Humans Compared to Other Forms
Cuenoud, B. M., Rochat, I., Gosoniu, M., Dupuis, L., Berk, E. S., Jaudszus, A., Mainz, J. G., Hafen, G., Beaumont, M., & Cruz‐Hernandez, C. (2020) · Nutrients · doi:10.3390/nu12041014 · Cited by 38
Marangoni, F., Novo, G., Perna, G., Filardi, P. P., Pirelli, S., Ceroti, M., Querci, A., & Poli, A. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.11.048 · Cited by 32
Lefort, N., LeBlanc, R., Giroux, M., & Surette, M. E. (2016) · Journal of Nutritional Science · doi:10.1017/jns.2015.34 · Cited by 34
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Omachi, D. O., Aryee, A. N. A., & Onuh, J. O. (2024) · Nutrients · doi:10.3390/nu16152453 · Cited by 36
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Schnitzer, M. I., Monreal, C. M., & Powell, E. E. (2013) · Journal of Environmental Science and Health Part B · doi:10.1080/03601234.2013.836924 · Cited by 32
Imamura, S., Morioka, T., Yamazaki, Y., Numaguchi, R., Urata, H., Motoyama, K., Mori, K., Fukumoto, S., Shoji, T., Emoto, M., et al. (2014) · Metabolism · doi:10.1016/j.metabol.2014.08.003 · Cited by 31
Tejera, N., Vauzour, D., Betancor, M. B., Sayanova, O. V., Usher, S. L., Cochard, M., Rigby, N. M., Ruiz‐López, N., Menoyo, D., Tocher, D. R., et al. (2016) · Journal of Nutrition · doi:10.3945/jn.115.223941 · Cited by 33
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Bordoni, L., Petracci, I., Zhao, F., Min, W., Pierella, E., Assmann, T. S., Martínez, J. A., & Gabbianelli, R. (2021) · Antioxidants · doi:10.3390/antiox10070994 · Cited by 38
Laake, K., Myhre, P. L., Nordby, L. M., Seljeflot, I., Abdelnoor, M., Smith, P., Tveit, A., Arnesen, H., & Solheim, S. (2014) · BMC Geriatrics · doi:10.1186/1471-2318-14-74 · Cited by 31
Shinto, L. H., Raber, J., Mishra, A., Roese, N. E., & Silbert, L. C. (2022) · Metabolites · doi:10.3390/metabo12090826 · Cited by 28
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Arnoldussen, I. A. C., & Kiliaan, A. J. (2014) · Marine Drugs · doi:10.3390/md12126190 · Cited by 31
Titan, S., Venturini, G., Padilha, K., Goulart, A. C., Lotufo, P. A., Benseñor, I. M., Krieger, J. E., Thadhani, R., Rhee, E. P., & Pereira, A. C. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213764 · Cited by 29
Razny, U., Kiec-Wilk, B., Polus, A., Goralska, J., Malczewska-Malec, M., Wnek, D., Zdzienicka, A., Gruca, A., Childs, C. E., Kapusta, M., et al. (2015) · BBA Clinical · doi:10.1016/j.bbacli.2015.05.001 · Cited by 27
Rossmeisl, M., Pavlišová, J., Janovská, P., Kuda, O., Bardová, K., Hansíková, J., Svobodová, M., Oseeva, M., Veleba, J., Kopecký, J., et al. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.03.011 · Cited by 27
Omega-3 and cardiovascular prevention – Is this still a choice?
Ruscica, M., Sirtori, C. R., Carugo, S., Calder, P. C., & Corsini, A. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106342 · Cited by 29
Richter, C. K., Bisselou, K. S., Nordgren, T. M., Smith, L. M., Appiah, A. K., Hein, N. A., Anderson‐Berry, A., Kris‐Etherton, P. M., Hanson, C., & Skulas‐Ray, A. C. (2019) · Lipids · doi:10.1002/lipd.12146 · Cited by 27
Minamino, H., Katsushima, M., Torii, M., Hashimoto, M., Fujita, Y., Ikeda, K., Yamamoto, W., Watanabe, R., Murakami, K., Murata, K., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-84479-0 · Cited by 27
Maki, K. C., & Dicklin, M. R. (2018) · Nutrients · doi:10.3390/nu10070864 · Cited by 26
Miura, K., Hughes, M. C. B., Ungerer, J. P. J., & Green, A. C. (2016) · Nutrition Research · doi:10.1016/j.nutres.2016.09.006 · Cited by 23
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Venø, S. K., Schmidt, E. B., & Bork, C. S. (2019) · Nutrients · doi:10.3390/nu11071467 · Cited by 24
Song, T., Cho, H.-J., Chang, Y., Choi, K., Jung, A.-R., Youn, M., Shin, M., & Kim, Y. (2015) · Journal of Stroke · doi:10.5853/jos.2015.17.2.168 · Cited by 24
Henao, J. J. A., Metherel, A. H., Smith, R. W. P., & Stark, K. D. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b03030 · Cited by 24
Recent Science and Clinical Application of Nutrition to Coronary Heart Disease
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Otsuka, R., Tange, C., Nishita, Y., Tomida, M., Kato, Y., Imai, T., Ando, F., & Shimokata, H. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16101806 · Cited by 22
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Giroli, M., Werba, J. P., Risé, P., Porro, B., Sala, A., Amato, M., Tremoli, E., Bonomi, A., & Veglia, F. (2021) · Nutrients · doi:10.3390/nu13072389 · Cited by 26
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Gautam, M., Izawa, A., Shiba, Y., Motoki, H., Takeuchi, T., Okada, A., Tomita, T., Miyashita, Y., Koyama, J., & Ikeda, U. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107003 · Cited by 23
Fatty Acid and Cholesterol Concentrations in Usually Consumed Fish in Brazil
Scherr, C., Gagliardi, A. C. M., Miname, M. H., & Santos, R. D. (2014) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20140176 · Cited by 22
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Iyngkaran, P., Liew, D., McDonald, P., Thomas, M. C., Reid, C. M., Chew, D. P., & Hare, D. L. (2016) · Current Cardiology Reviews · doi:10.2174/1573403x12666160606121458 · Cited by 21
Burak, C., Wolffram, S., Zur, B., Langguth, P., Fimmers, R., Alteheld, B., Stehle, P., & Egert, S. (2017) · British Journal Of Nutrition · doi:10.1017/s0007114517000241 · Cited by 21
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Sun, L., Zong, G., Li, H., & Lin, X. (2020) · European Journal of Clinical Nutrition · doi:10.1038/s41430-020-00709-0 · Cited by 22
Clinical significance of polyunsaturated fatty acids in the prevention of cardiovascular diseases
Kotlyarov, S. N., & Котлярова, А. А. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.998291 · Cited by 22
Microbial Production of Fatty Acids
Ratledge, C., & Lippmeier, J. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809521-8.00006-4 · Cited by 21
Villegas, R., Takata, Y., Murff, H. J., & Blot, W. J. (2015) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2015.04.006 · Cited by 20
Ismail, T. A., Soliman, M. M., NASSAN, M. A., & Mohamed, D. I. (2015) · Journal of Food and Nutrition Research · doi:10.12691/jfnr-3-2-1 · Cited by 20
Eide, I. A., Reinholt, F. P., Jenssen, T. G., Hartmann, A., Schmidt, E. B., Åsberg, A., Bergan, S., Brabrand, K., & Svensson, M. H. S. (2018) · American Journal of Transplantation · doi:10.1111/ajt.15080 · Cited by 20
Simopoulos, A. P. (2014) · Lifestyle Genomics · doi:10.1159/000375495 · Cited by 20
Yang, B., Ren, X.-L., Huang, H. L., Guo, X., Ma, A., & Li, D. (2017) · Oncotarget · doi:10.18632/oncotarget.19530 · Cited by 19
Self-citationPavlišová, J., Horakova, O., Kalendová, V., Buresova, J., Bardová, K., Holendová, B., Plecitá‐Hlavatá, L., Vacková, Š., Windrichová, J., Topolčan, O., et al. (2020) · Food & Function · doi:10.1039/d0fo01942a · Cited by 20
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Davidson, M. H., & Benes, L. B. (2016) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000353 · Cited by 18
Nguyen, D. V., Le, H. V., Nguyen, Q. V., Malau‐Aduli, B. S., Nichols, P. D., & Malau‐Aduli, A. E. O. (2017) · Nutrients · doi:10.3390/nu9080893 · Cited by 18
Docosapentaenoic acid and lung cancer risk: A Mendelian randomization study
Liu, J., Zhou, H., Zhang, Y., Huang, Y., Fang, W., Yang, Y., Hong, S., Chen, G., Zhao, S., Chen, X., et al. (2019) · Cancer Medicine · doi:10.1002/cam4.2018 · Cited by 18
Xiao, Y., Li, X., Zeng, X., Wang, H., Mai, Q., Cheng, Y., Li, J., Tang, L., & Ding, H. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b02110 · Cited by 18
Bonafini, S., & Fava, C. (2017) · Prostaglandins & other lipid mediators · doi:10.1016/j.prostaglandins.2017.01.004 · Cited by 15
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Pinel, A., Rigaudière, J., Jouve, C., & Capel, F. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092778 · Cited by 17
Shaikh, N. A., Yantha, J., Shaikh, S., Rowe, W., Laidlaw, M., Cockerline, C., Ali, A., Holub, B., & Jackowski, G. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2132-1 · Cited by 16
Dawczynski, C. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2020.608854 · Cited by 16
Skarsfeldt, M. A., Liin, S. I., Larsson, H. P., & Bentzen, B. H. (2020) · Acta Physiologica · doi:10.1111/apha.13471 · Cited by 16
Zhuang, P., Wang, W., Wang, J., Zhang, Y., & Jiao, J. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700898 · Cited by 16
Zhang, Y., Guo, X., Gao, J., Wei, C., Zhao, S., Liu, Z., Sun, H., Wang, J., Liu, L., Li, Y., et al. (2021) · Annals of Medicine · doi:10.1080/07853890.2021.1937693 · Cited by 15
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Oseeva, M., Paluchová, V., Žáček, P., Janovská, P., Mráček, T., Rossmeisl, M., Hamplová, D., Čadová, N., Štohanzlová, I. (., Flachs, P., et al. (2019) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2019.02.006 · Cited by 15
Demonty, I., Langlois, K. A., Greene-Finestone, L. S., Zoka, R., & Nguyen, L. (2020) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa401 · Cited by 17
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Lelli, D., Incalzi, R. A., Ferrucci, L., Bandinelli, S., & Pedone, C. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.02.030 · Cited by 14
McBurney, M. I., Blumberg, J. B., Costello, R. B., Eggersdorfer, M. L., Erdman, J. W., Harris, W. S., Johnson, E. J., Mitmesser, S. H., Post, R. C., Rai, D., et al. (2021) · Nutrients · doi:10.3390/nu13061844 · Cited by 14
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McCarty, M. F., DiNicolantonio, J. J., Lavie, C. J., & O’Keefe, J. H. (2014) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2013.10.029 · Cited by 14
Willis, M. S., Ilaiwy, A., Montgomery, M. D., Simpson, P. C., & Jensen, B. C. (2016) · Metabolomics · doi:10.1007/s11306-016-1097-3 · Cited by 14
Welty, F. K., Daher, R., & Garelnabi, M. (2023) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.122.318125 · Cited by 14
Xiao, Y., Chen, Y., Pietzner, A., Elbelt, U., Fan, Z., & Weylandt, K. H. (2024) · Nutrients · doi:10.3390/nu16111610 · Cited by 15
Feng, Q., Li, G., Xia, W., Dai, G., Zhou, J., Xu, Y., Liu, D., & Zhang, G. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.983501 · Cited by 13
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Clayton, P., & Ladi, S. (2015) · Journal of the Royal Society of Medicine · doi:10.1177/0141076815599673 · Cited by 12
Nguyen, Q. V., Le, H. V., Nguyen, D. V., Malau‐Aduli, B. S., Nichols, P. D., & Malau‐Aduli, A. E. O. (2018) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201700256 · Cited by 13
Laguzzi, F., Alsharari, Z. D., Risérus, U., Vikström, M., Sjögren, P., Gigante, B., Hellénius, M.-L., Cederholm, T., Bottai, M., Fairé, U. D., et al. (2015) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12336 · Cited by 12
Lentjes, M. A. H., Keogh, R. H., Welch, A. A., Mulligan, A. A., Luben, R., Wareham, N. J., & Khaw, K. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-017471 · Cited by 12
Sun, T., Tolba, S. A., Magnuson, A. D., & Lei, X. G. (2022) · Algal Research · doi:10.1016/j.algal.2022.102648 · Cited by 13
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Harris, W. S., Pottala, J. V., Thiselton, D. L., Varvel, S. A., Baedke, A. M., Dayspring, T. D., Warnick, G. R., & McConnell, J. P. (2014) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-014-9554-8 · Cited by 11
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Chowdhury, R., Steur, M., Patel, P. S., & Franco, O. H. (2016) · Elsevier eBooks · doi:10.1016/b978-1-63067-036-8.00010-x · Cited by 13
Isaksen, T., Evensen, L. H., Brækkan, S. K., & Hansen, J. (2019) · Thrombosis and Haemostasis · doi:10.1055/s-0039-1697663 · Cited by 11
Yokoyama, Y., Kuno, T., Morita, S. X., Slipczuk, L. N., Takagi, H., Briasoulis, Α., Latib, A., Bangalore, S., & Heffron, S. P. (2022) · Journal of Cardiology · doi:10.1016/j.jjcc.2022.07.008 · Cited by 11
Cupino, A., Fraser, G. E., Knutsen, S. F., Knutsen, R., Heskey, C. E., Sabaté, J., & Shavlik, D. J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0274109 · Cited by 12
Ly, R., MacIntyre, B. C., Philips, S. M., McGlory, C., Mutch, D. M., & Britz‐McKibbin, P. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100445 · Cited by 14
Bork, C. S., Tram, L., Hjelmgaard, K., & Schmidt, E. B. (2020) · Proceedings of The Nutrition Society · doi:10.1017/s0029665120006886 · Cited by 11
Hawley, A. L., & Baum, J. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuad061 · Cited by 11
Mueller, P. A., Bergstrom, P., Rosário, S., Heard, M. E., & Pamir, N. (2024) · Journal of Nutrition · doi:10.1016/j.tjnut.2024.01.007 · Cited by 12
Laake, K., Seljeflot, I., Schmidt, E. B., Myhre, P. L., Tveit, A., Arnesen, H., & Solheim, S. (2016) · Journal of Lipids · doi:10.1155/2016/4945720 · Cited by 10
Maki, K. C. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy205 · Cited by 9
Shaikh, N., & Tappia, P. S. (2015) · Clinical Lipidology · doi:10.2217/clp.15.1 · Cited by 10
Monge, A., Harris, W. S., Ortiz‐Panozo, E., Yunes, E. M., Cantú-Brito, C. G., Catzín‐Kuhlmann, A., López‐Ridaura, R., & Lajous, M. (2016) · Journal of Nutrition · doi:10.3945/jn.115.227264 · Cited by 10
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Wang, L., Sikand, G., & Wong, N. D. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801816-3.00023-6 · Cited by 10
Metadata
- Authors
- Mozaffarian, D., Lemaitre, R. N., King, I. B., Song, X., Huang, H., Sacks, F. M., Rimm, E. B., Wang, M., & Siscovick, D. S.
- Affiliations
- Brigham and Women's Hospital (US)
- From Brigham and Women's Hospital, Harvard Medical School, and Harvard School of Public Health, Boston, Massachusetts; University of New Mexico, Albuquerque, New Mexico; and Fred Hutchinson Cancer Research Center and University of Washington, Seattle, Washington.
- ORCID
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 2013-04-02
- Volume
- 158
- Issue
- 7
- Pages
- 515-525
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- PMC
- PMC3698844
- OpenAlex
- W2015008724
- Cited by
- 283
- References
- 61
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 13 · 2023: 9 · 2022: 13 · 2021: 19 · 2020: 24 · 2019: 20 · 2018: 30 · 2017: 23 · 2016: 29 · 2015: 37 · 2014: 26 · 2013: 19
- FWCI
- 34.21
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- Funders
- National Institutes of Health (n01hc085082-026, n01hc085081-021, n01hc045133-001, n01hc085079-024, n01hc015103-009, n01hc085084-005, n01hc085085-011, n01hc085083-027, n01hc085080-026, n01hc085086-022, n01hc55222-0-0-0, n01hc075150-004, n01hc035129-010)
- National Institute on Aging (AG 20098, R56AG023629, R01AG020098, AG023629, AG027058, R56AG020098, R01AG023629, R01AG015928, R01AG027058)
- National Heart, Lung, and Blood Institute (N01-HC-85081, N01HC85085, N01 HC085086, N01HC-85083, N0-1-HC-85239, N01 HC085079, N01HC85082, N01HC‐75150, N01 HC85086, N01 HC035129, N01HC85080, N01 HC015103, N01 HC55222, HHSN268201200036C, U01HL080295, N01 HC055222, R01HL085710, HL080295, R01HL080295, N01 HC075150, N01 HC045133, N01-HC85079, N01-HC85084)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Keywords
- plasma phospholipid fatty acids, eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid, all-cause mortality, cause-specific mortality, cardiovascular mortality, coronary artery disease, stroke, older adults, primary prevention, dietary fatty acids, dietary biomarkers, dose-response relationship
- MeSH terms
- Aged, Cause of Death, Coronary Disease, Docosahexaenoic Acids, Fatty Acids, Unsaturated, Feeding Behavior, Female, Humans, Male, Prospective Studies, Eicosapentaenoic Acid, Biomarkers, Fatty Acids, Omega-3, Diet Records, Risk Assessment, Stroke
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