Contagious Ecthyma, Rangiferine Brucellosis, and Lungworm Infection in a Muskox (Ovibos moschatus) from the Canadian Arctic, 2014
Abstract
An adult male muskox ( Ovibos moschatus ), harvested on 26 August 2014 on Victoria Island, Nunavut, in the Canadian Arctic, had proliferative dermatitis on the muzzle and fetlocks suggestive of contagious ecthyma or orf (Parapoxvirus). Histopathologic features of the lesions were consistent with this diagnosis. Orf virus DNA, phylogenetically similar to an isolate from a captive muskox of the Minnesota Zoo, US, was detected in the lesions by PCR using Parapoxvirus primers. Additionally, there was a metaphyseal abscess with a cortical fistula in the right metacarpus from which Brucella suis biovar 4 was isolated and identification supported by PCR. Brucella spp. antibodies were detected in serum. Finally, 212 nodules were dissected from the lungs. Fecal analysis and lung examination demonstrated co-infection with the lungworms Umingmakstrongylus pallikuukensis and Varestrongylus eleguneniensis. The zoonotic potential of orf and rangiferine brucellosis adds an important public health dimension to this case, particularly given that muskoxen are a valuable source of food for Arctic residents. Careful examination of these pathogens at a population level is needed as they may contribute to muskox population decline and potentially constitute a driver of food insecurity for local communities. This case underscores the importance of wildlife health surveillance as a management tool to conserve wildlife populations and maintain food security in subsistence-oriented communities.
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Changing pathogen distribution and disease dynamics have been observed with climate-driven range expansion of the lung nematode Umingmakstrongylus pallikuukensis in the Northwest Territories and Nunavut, the emergence of parapox virus, and increasing observations of Brucella-like lesions on Victoria Island, Canada.
“Changing pathogen distribution and disease dynamics have also been observed with climate-driven range expansion of the lung nematode Umingmakstrongylus pallikuukensis in the Northwest Territories and Nunavut (Kutz et al. 2013a, b; Kafle et al. 2017), the emergence of parapox virus, and increasing observations of Brucella-like lesions on Victoria Island, Canada (Tomaselli et al. 2016).”
From Muskox status, recent variation, and uncertain future (2020) · cites this paper as Tomaselli et al. 2016
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Self-citation
- Authors
- Tomaselli, M., Dalton, C., Duignan, P. J., Kutz, S., van der Meer, F., Kafle, P., Surujballi, O., Turcotte, C., & Checkley, S.
- Affiliations
- University of Calgary (CA)
- Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6, Canada;
- Canadian Food Inspection Agency (CA)
- Corresponding author
- Tomaselli, Matilde
- Venue
- Journal of Wildlife Diseases
- Publisher
- Wildlife Disease Association
- Published
- 2016-07
- Volume
- 52
- Issue
- 3
- Pages
- 719-724
- ISSN
- 0090-3558 (ISSN-L)
- OpenAlex
- W2411186622
- Cited by
- 37
- References
- 20
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 4 · 2023: 2 · 2022: 6 · 2021: 5 · 2020: 4 · 2019: 2 · 2018: 5 · 2017: 5
- FWCI
- 6.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Wildlife Diseases (publishedVersion)
- PubMed (publishedVersion)
- BioOne Complete (BioOne) (submittedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Brucella: diagnosis, epidemiology, treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Zoonotic diseases and public health
- Life Sciences › Immunology and Microbiology › Virology › Poxvirus research and outbreaks
- Keywords
- Ovibos moschatus, contagious ecthyma, open reading frames, parapoxvirus, lungworm infection, co-infection, zoonotic potential, wildlife health monitoring, food security, subsistence hunting, Arctic fauna, Nunavut
- MeSH terms
- Animals, Arctic Regions, Brucellosis, Canada, Ecthyma, Contagious, Lung Diseases, Parasitic, Male, Nematode Infections, Orf virus, Phylogeny, Ruminants
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