Lifestyle Medicine: A Brief Review of Its Dramatic Impact on Health and Survival
Open accessAbstract
By ignoring the root causes of disease and neglecting to prioritize lifestyle measures for prevention, the medical community is placing people at harm. Advanced nations, influenced by a Western lifestyle, are in the midst of a health crisis, resulting largely from poor lifestyle choices. Epidemiologic, ecologic, and interventional studies have repeatedly indicated that most chronic illnesses, including cardiovascular disease, cancer, and type 2 diabetes, are the result of lifestyles fueled by poor nutrition and physical inactivity.In this article, we describe the practice of lifestyle medicine and its powerful effect on these modern instigators of premature disability and death. We address the economic benefits of prevention-based lifestyle medicine and its effect on our health care system: A system on the verge of bankruptcy. We recommend vital changes to a disastrous course. Many deaths and many causes of pain, suffering, and disability could be circumvented if the medical community could effectively implement and share the power of healthy lifestyle choices. We believe that lifestyle medicine should become the primary approach to the management of chronic conditions and, more importantly, their prevention. For future generations, for our own health, and for the Hippocratic Oath we swore to uphold ("First do no harm"), the medical community must take action. It is our hope that the information presented will inspire our colleagues to pursue lifestyle medicine research and incorporate such practices into their daily care of patients. The time to make this change is now.
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PCOS is a reversible metabolic condition that makes a significant contribution to the global epidemic of lifestyle-related chronic disease.
“Polycystic ovary syndrome is a reversible metabolic condition that makes a significant contribution to the global epidemic of lifestyle-related chronic disease [1,2,3].”
From Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment (2022) · cites this paper as [1]
The Introduction discusses inflammation, obesity, and type 2 diabetes as lifestyle-related conditions, and the Discussion says many conditions are reversible. Neither passage identifies polycystic ovary syndrome (PCOS) or says it contributes to a global chronic-disease epidemic. Searches for PCOS and 'reversible metabolic condition' found no passage addressing that specific claim. (LLM, conf=0.75)
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- Authors
- Bodai, B. I., Nakata, T. E., Wong, W. T., Clark, D. R., Lawenda, S., Tsou, C., Liu, R., Shiue, L., Cooper, N., Rehbein, M., Ha, B. P., McKeirnan, A., Misquitta, R., Vij, P., Klonecke, A., Mejia, C. S., Dionysian, E., Hashmi, S., Greger, M., Stoll, S., & Campbell, T. M.
- Affiliations
- Director of The Breast Cancer Survivorship Institute in Sacramento, CA..
- Program Manager of The Breast Cancer Survivorship Institute in Sacramento, CA..
- Psychiatrist at the Redwood City Medical Center in CA..
- Kaiser Permanente Baldwin Park Medical Center (US)
- Antelope Valley Hospital (US)
- Internist at the San Jose Medical Center in CA..
- University of California San Francisco Medical Center (US)
- Radiologist at the Glenlake Medical Center in Atlanta, GA..
- Pediatrician and Assistant Physician-in-Charge for Outpatient Service at the Stockton Medical Office in CA..
- Associate Area Medical Director for Family Medicine at the Bakersfield Medical Center in CA..
- Obstetrician/Gynecologist at the San Diego Medical Center in CA..
- Kaiser Permanente South Sacramento Medical Center (US)
- Kaiser Permanente (US)
- University of California Davis Medical Center (US)
- Internist at the Skyline Medical Offices in Salem, OR..
- Orthopedic Surgeon at the Lakeview Medical Offices and at the Orange County Medical Center in Anaheim, CA..
- Woodland Hills Medical Center (US)
- Physician and Founder of NutritionFacts.org in Kensington, MD..
- Co-Founder and Chairman of the Plantrician Project in Rieglesville, PA..
- University of Rochester Medicine (US)
- Venue
- The Permanente Journal
- Publisher
- The Permanente Federation
- Published
- 2018-03
- Volume
- 22
- Issue
- 1
- Pages
- 17-025
- ISSN
- 1552-5767 (ISSN-L)
- 1552-5775
- PMC
- PMC5638636
- OpenAlex
- W2754369670
- Cited by
- 253
- References
- 166
- Citations by year
- 2026: 17 · 2025: 30 · 2024: 33 · 2023: 73 · 2022: 21 · 2021: 30 · 2020: 28 · 2019: 13 · 2018: 8
- FWCI
- 21.72
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Permanente Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centers for Disease Control and Prevention
- Topics
- Health Sciences › Health Professions › General Health Professions › Health and Lifestyle Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Psychiatry and Mental health › Medicine, History, and Philosophy
- Keywords
- lifestyle medicine, chronic disease prevention, cardiovascular disease, cancer, type 2 diabetes, physical inactivity, poor nutrition, Western lifestyle, health care costs, health system sustainability, primary care, Hippocratic Oath
- MeSH terms
- Healthy Lifestyle, Chronic Disease, Humans, Preventive Health Services, Preventive Medicine, Public Health, Health Behavior, Risk Reduction Behavior
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