Tsubota, Kazuo

Loss of epigenetic information as a cause of mammalian aging

Yang, J.-H., Hayano, M., Griffin, P. T., Amorim, J. A., Bonkowski, M. S., Apostolides, J. K., Salfati, E. L., Blanchette, M., Munding, E. M., Bhakta, M., et al. (2023) · Cell

Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation

Cited by 643

Effects of blue light on the circadian system and eye physiology

Tosini, G., Ferguson, I., & Tsubota, K. (2016) · Molecular Vision

Circadian rhythm and melatoninOcular and Laser Science Research

Cited by 517

Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: A model of age-related macular degeneration

Imamura, Y., Noda, S., Hashizume, K., Shinoda, K., Yamaguchi, M., Uchiyama, S., Shimizu, T., Mizushima, Y., Shirasawa, T., & Tsubota, K. (2006) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 420

TFOS DEWS II introduction

Nelson, J. D., Craig, J. P., Akpek, E. K., Azar, D. T., Belmonte, C., Bron, A. J., Clayton, J. A., Dogru, M., Dua, H. S., Foulks, G. N., et al. (2017) · The Ocular Surface

Ocular Surface and Contact LensAdvanced Drug Delivery Systems

Cited by 287

Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies

Hatori, M., Gronfier, C., Van Gelder, R. N., Bernstein, P. S., Carreras, J., Panda, S., Marks, F., Sliney, D., Hunt, C. E., Hirota, T., et al. (2017) · npj Aging and Mechanisms of Disease

Circadian rhythm and melatoninImpact of Light on Environment and Health

Cited by 212

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., et al. (2020) · Endocrine Journal

Sirtuins and Resveratrol in MedicineFolate and B Vitamins Research

Cited by 191

Melanocytes in the corneal limbus interact with K19-positive basal epithelial cells

Higa, K., Shimmura, S., Miyashita, H., Shimazaki, J., & Tsubota, K. (2005) · Experimental Eye Research

melanin and skin pigmentationCorneal Surgery and Treatments

Cited by 97

Role of bile acids in the regulation of the metabolic pathways

Taoka, H., Yokoyama, Y., Morimoto, K., Kitamura, N., Tanigaki, T., Takashina, Y., Tsubota, K., & Watanabe, M. (2016) · World Journal of Diabetes

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 80

Protective effect of blue-light shield eyewear for adults against light pollution from self-luminous devices used at night

Ayaki, M., Hattori, A., Maruyama, Y., Nakano, M., Yoshimura, M., Kitazawa, M., Negishi, K., & Tsubota, K. (2016) · Chronobiology International

Circadian rhythm and melatoninImpact of Light on Environment and Health

Cited by 77

Dietary restriction: standing up for sirtuins

Baur, J. A., Chen, D., Chini, E. N., Chua, K., Cohen, H. Y., Cabo, R. D., Deng, C., Dimmeler, S., Gius, D., Guarente, L. P., et al. (2010) · Science

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 76

Smartphone viewing distance and sleep: an experimental study utilizing motion capture technology

Yoshimura, M., Kitazawa, M., Maeda, Y., Mimura, M., Tsubota, K., & Kishimoto, T. (2017) · Nature and Science of Sleep

Ergonomics and Musculoskeletal DisordersSleep and related disorders

Cited by 67

ENLIGHT: A consensus checklist for reporting laboratory-based studies on the non-visual effects of light in humans

Spitschan, M., Kervezee, L., Lok, R., McGlashan, E., Najjar, R. P., Allen, A. E., Andersen, M., Bará, S., Blattner, P., Blume, C., et al. (2023) · eBioMedicine

Delphi Technique in ResearchCircadian rhythm and melatonin

Cited by 60

Effects of dietary supplementation with fish oil on dry eye syndrome subjects: randomized controlled trial

KAWAKITA, T., KAWABATA, F., TSUJI, T., KAWASHIMA, M., SHIMMURA, S., & TSUBOTA, K. (2013) · Biomedical Research

Ocular Surface and Contact LensFatty Acid Research and Health

Cited by 48

Evaluation of AAV-DJ vector for retinal gene therapy

Katada, Y., Kobayashi, K., Tsubota, K., & Kurihara, T. (2019) · PeerJ

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 46

Transplantation of side population cells restores the function of damaged exocrine glands through clusterin

Mishima, K., Inoue, H., Nishiyama, T., Mabuchi, Y., Amano, Y., Ide, F., Matsui, M., Yamada, H., Yamamoto, G., Tanaka, J., et al. (2012) · Stem Cells

Mesenchymal stem cell researchClusterin in disease pathology

Cited by 42

Violet Light Modulates the Central Nervous System to Regulate Memory and Mood

Sasaki, N., Gusain, P., Hayano, M., Sugaya, T., Tonegawa, N., Hatanaka, Y., Tamura, R., Okuyama, K., Osada, H., Ban, N., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 5